Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
The MONARCH study investigates if home eye tests can detect wet age-related macular degeneration (AMD) in patients, potentially reducing unnecessary hospital appointments and costs. Patients will complete three home eye tests weekly for one to two years, with results compared to hospital check-ups.
A new study published in the Journal of Health and Social Behavior found a strong link between unfair treatment by police and telomere length, a biological indicator of psychological stress, among black men. Telomeres were shorter for those reporting unfair treatment, and the link was more pronounced in black men.
A study published in JAMA Internal Medicine reveals six high-quality instruments to measure delirium severity, enabling accurate assessment and improving clinical care. The findings have the potential to stratify risk, target treatment, and monitor outcomes for persons with delirium.
Researchers found that activating the locus coeruleus (LC) improves sensory information transmission and perceptual performance. The study provides insights into new treatments for neurological disorders, including Parkinson's disease and depression.
Researchers found that relationship impairment interferes with treatment seeking among post-9/11 military veterans, particularly men, while facilitating treatment seeking among women. The study suggests a sex difference in the role of relationships on treatment use.
Researchers found that maintaining systolic blood pressure at around 140 mmHg experienced fewer negative health outcomes, such as second strokes, death or cardiovascular disease. The findings provide some clarity for physicians, but more research is needed to confirm the optimal level of blood pressure.
Ning Jiang, a UT Austin researcher, will investigate immune cell behavior in neurodegenerative diseases with a $2.5 million grant. This funding supports a collaborative project aiming to improve understanding of Alzheimer's and Parkinson's diseases.
A Finnish study of 68,800 patients found that hip fracture surgery is associated with a significant risk of surgical complications. Patients with osteoarthritis, Parkinson's disease, and rheumatic diseases are particularly at risk, with 4.6% experiencing complications within three months of surgery.
Research finds that socio-economic conditions in regions affect T1 diabetes treatment, with disadvantaged areas having higher blood glucose levels, lower use of pump therapy and CGMS, and better outcomes for severe hypoglycemia. Frequent use of pump therapy and CGMS could improve treatment outcomes in these regions.
Scientists have identified a previously unknown structural change within cells that triggers the activation of the inflammasome, a multiprotein complex involved in inflammation. This finding provides a new avenue for developing therapeutics to target the NLRP3 pathway for inflammatory diseases.
Annual telemedicine visits increased from 0.02 to 6.57 per 1,000 members between 2005-2017, with growth accelerating after 2015. Most users resided in urban areas, a trend contrasting with the emphasis on expanding telemedicine access in rural regions.
Researchers from the University of Eastern Finland used postal code area data to assess treatment outcomes in type 2 diabetes patients. The study found that lower educational attainment levels in postal code areas were associated with higher long-term blood glucose values, indicating a need for targeted health care services.
A new animal model of age-related macular degeneration has been developed, allowing researchers to study the environmental risk factors that promote the condition. The model replicates aspects of human AMD, including lipid accumulation and inflammation, which can lead to vision loss.
Researchers developed a new AI method to evaluate treatment effectiveness in individual patients. The method uses causal Bayesian networks and was applied to obstructive sleep apnea treatment, showing reduced mortality rates by 5%.
The new guidelines provide an update to the previously published consensus on definition and diagnosis of sarcopenia. They include an easier way to screen for sarcopenia risk using a simple questionnaire, a systematic way to make the sarcopenia diagnosis, and suggestions for practical tools and tests at each step.
A new study has found that footballers' health screens, including echocardiography and electrocardiography, do not always detect potentially critical heart problems. In fact, six players out of 595 tested negative for serious cardiovascular issues, highlighting the need for further screening and timely symptom reporting.
The 5-year project will investigate diagnosis, treatment, and prevention of Chronic Traumatic Encephalopathy (CTE) in former NFL players. Researchers will track up to 2,500 players with annual follow-up health assessments to examine associations between clinical outcomes and abnormal tau buildup.
A study published in Optometry and Vision Science found that dry eye syndrome can slow a person's reading speed by up to 10% and make it difficult to read for more than 30 minutes. The condition affects millions of adults in the US, causing ocular discomfort and visual problems.
A Los Angeles County Department of Mental Health campaign targeting youth aged 14-24 showed impressive results in changing public attitudes toward mental health. The 'WhyWeRise' campaign increased support for people with mental illness and empowered youth to mobilize around mental health activism.
A new 15-minute brain scan predicts damage with 98% accuracy, helping doctors assess the extent of newborn brain damage and plan for long-term development. The scan may also aid in developing new treatments for brain injury in babies.
A survey found that 16% of adults in England used complementary and alternative medicine, with unequal access to these treatments. CAM use was more common among women and those in higher socioeconomic groups, particularly in the south of England.
The study found that performance coaching significantly increased rates of tobacco dependence treatment delivery among primary care clinicians. Clinicians who received coaching had higher rates of providing key elements of the 5As model and arranging follow-up support.
A new study published in JAMA Ophthalmology found that traditional glaucoma tests often underestimate the severity of central vision loss. Researchers developed a finer visual field test to assess macular damage and found it can improve diagnosis at no extra cost.
Dr. M. Brandon Westover has been awarded a two-year, $300,000 BIG Award to develop methods to track brain aging by monitoring brain rhythms during sleep. The goal is to create a low-cost marker of brain age that may help identify individuals at risk of age-related cognitive impairment.
Researchers at University of Copenhagen create technique to observe and measure fetal heart rhythms without direct electrode placement. The method uses a cloud of caesium atoms to detect small magnetic fields, mimicking the effect of placing an instrument on a pregnant woman's belly.
New reviews on symptom stability over time for bipolar disorder and psychotic disorders highlight the importance of diagnostic accuracy for prognosis and treatment. Diagnostic instability is associated with factors such as extreme age, female sex, and substance abuse, emphasizing the need for enhanced tools to quantify risk.
A new study found that exposing people with phobias to their fear at the exact time of their heartbeats significantly reduces phobia severity. Researchers combined computerized therapy with online heart rhythm measurements to treat patients with spider phobia, showing improved anxiety levels and reduced physiological responses.
A University of California San Diego School of Medicine team will investigate a novel treatment model called Regulation of Cues (ROC) to tackle binge eating disorder and obesity in military personnel. ROC targets underlying mechanisms associated with binge eating, aiming to reduce weight and obesity.
A new study published in Frontiers in Neurology found that robotic arm rehabilitation can promote speech and language function recovery in chronic stroke patients with aphasia. The research team observed small but consistent improvement on measures assessing speech articulation and overall language processing.
The Society of Vascular and Interventional Neurology presents the latest clinical trials and breakthrough technology related to vacuum aspiration for removing blood clots in stroke patients. The results aim to improve the lives of stroke patients worldwide.
A panel of international experts recommends stopping oxygen therapy in patients with normal oxygen levels above 96% and not starting it for certain conditions. The guidelines aim to minimize harm from excessive oxygen use, which increases mortality.
A recent study found a significant increase in mental health diagnoses and treatment among US university students between 2009 and 2015. Anxiety, depression, and panic attacks saw the biggest increases, with anxiety now affecting almost 15% of students nationally.
Low-income obese patients lost a clinically meaningful amount of weight using a free phone app and coaching calls in a primary care clinic. The study found that 43% of participants lost more than 5% of their body weight, while 56% reached a healthy weight loss threshold.
A randomized, placebo-controlled study has shown that cannabis oil can produce clinical remission in up to 65% of individuals with moderately severe Crohn's disease after 8 weeks of treatment. However, the improvement does not appear to result from a dampening down of the underlying inflammatory process.
The 11th World Stroke Congress highlights the high impact of stroke in low- and middle-income countries, with over 80% of global stroke burden concentrated in these regions. Experts discuss prevention and treatment strategies to reduce premature mortality from stroke by one-third by 2030.
A nationwide study found large regional differences in endoscopic sinus surgery rates due to chronic rhinosinusitis in Finland. The highest rates were observed in public hospitals, suggesting a correlation between the availability of medical services and ESS rates.
A new study published in Pediatric Research found that children with asthma growing up in polluted NYC neighborhoods need emergency medical treatment more often. The study suggests that these areas may have other environmental factors affecting urgent asthma treatment.
Research reveals abnormal vision in childhood can impact attention and brain development. Studies show that patients with lazy eye have difficulty directing attention to the weaker eye when both eyes are open.
A study published in Human Reproduction found that accounting for cellular variability in endometrial gene expression profiles improves the accuracy of biomarker discovery. This approach can increase IVF success rates for couples who have experienced repeated IVF failure.
The partnership aims to provide a voice-based user interface for an existing Epilepsy Patient Portal, allowing patients to co-author their electronic patient record. This enhanced system will facilitate real-time reporting of health information using the patients' voice, making it easier for clinicians and more useful for patients.
Researchers found that patients taking full-dose allopurinol for gout flares had a lower risk of developing Stage 3 Chronic Kidney Disease (CKD) compared to non-users. The use of allopurinol may be beneficial in reducing kidney disease risk, contrary to previous concerns.
The InforMing the PAthway of COPD Treatment (IMPACT) study found that triple dual therapies significantly reduced annual rates and moderate-to-severe exacerbations, improved lung function, and enhanced quality of life in patients with COPD. This benefit was observed regardless of baseline reversibility.
A recent analysis suggests that improving health care in Canada requires expanding public funding for cost-effective treatments, investing in primary care, and embracing technology. The authors propose engaging patients to determine services and standardizing quality-improvement tools to improve healthcare quality.
A user-friendly software tool models neural circuits in outer brain layers, enabling EEG-guided treatment for patients based on new knowledge of underlying neural circuits. The Human Neocortical Neurosolver is a free, open-source tool that can help bridge the gap between genetic and molecular changes to neural circuit level signals.
The UTHealth Homeless Outpatient Mental Health Expansion Services Program provides treatment and recovery support to 500 individuals ages 18 and older with serious mental illness experiencing homelessness.
A new study suggests that EU countries are unprepared to rapidly move future Alzheimer's treatment into clinical use due to shortages of medical specialists and infusion capacity. The study estimates that up to 1 million people may be left without access to transformative care if a breakthrough occurs.
Researchers found intravitreal treatments to be superior to periocular injections in reducing macular edema and improving visual acuity. The study suggests shifting towards intravitreal corticosteroid injections for treating uveitic macular edema.
The All of Us Research Program has awarded $28.6M to establish three genome centers, generating genomic data from 1 million biosamples contributed by program participants. These centers will provide critical data for precision medicine research and support studies on various health questions.
The ReCre8 trial found that a novel polymer-free amphilimus-eluting stent was clinically safe and effective, comparable to a durable polymer zotarolimus-eluting stent. The study showed that one-month DAPT in troponin-negative patients may be safe regarding stent thrombosis.
The BIONYX trial found that the Resolute Onyx stent is safe and effective in a complex patient population, with low rates of cardiac death and target vessel-related myocardial infarction. The stent's improved radiographic visibility facilitates accurate assessment of stent expansion and apposition to the arterial wall.
Researchers from Aarhus University have discovered a new type of fatty acid that can slow down the overactive STING protein, which is normally an important part of our immune system. This breakthrough has opened a new path to developing effective treatments for autoimmune diseases such as Lupus and SAVI.
A study of college students reveals significant disparities in mental health treatment across race and ethnicity, with white students receiving more treatment than students of color. The study found that half of white students received treatment, compared to one-quarter of African American and Asian students.
Concussion symptoms in children under 13 typically last three times longer than in adults, according to a comprehensive review published in The Journal of the American Osteopathic Association. Active recovery, including academics and athletics, has emerged as a standard treatment, promoting progressive return to school and sports, whil...
The University of Texas at San Antonio has received a grant to develop an innovative parent-assisted treatment program for infants as young as 6 months at risk for autism spectrum disorder. The project aims to identify biomarkers correlated with later autism diagnosis through electroencephalographic (EEG) technology.
Kessler Foundation will analyze the impact of its spatial neglect assessment and treatment protocols on stroke survivor recovery and independence. The two-year grant aims to confirm functional benefits and improve clinical benchmarks for stroke rehabilitation.
Researchers have discovered a marker that can help identify patients with severe asthma who are likely to respond well to new treatments. The marker targets inflammatory cells called eosinophils, which play a key role in the condition.
A new study found that 37% of adult smokers who tried vaping blu products completely switched to vaping after 90 days. The study also showed a significant reduction in daily smoking and cigarettes per day.
Researchers will investigate whether obstructive sleep apnea diagnosis and treatment improves stroke recovery or reduces the likelihood of another stroke. The study aims to determine whether future patients should be screened and treated for OSA to improve survival and recovery after a stroke.
Researchers at Aarhus University found that group and individual therapy can significantly reduce tics in children with Tourette's Syndrome. The study confirms the effectiveness of training strategies outlined in a new Danish manual, which combines multiple methods for treating the condition.
Scientists have discovered a three-pronged treatment that stimulates axon growth through scar tissue in rodents, potentially leading to therapies for humans. The approach triggers axon growth and transmission across damaged tissue, opening doors to restoring connections in people with spinal cord injury.