Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A study by the University of Göttingen found that in the Global South, more than two-thirds of people with high blood pressure go untreated. Only 30% of diagnosed patients receive treatment, and fewer than one-tenth have successfully controlled their disease.
Researchers found that initiating stroke treatment just 15 minutes faster can save lives and prevent disability. Busier hospitals, which treat more than 450 people for stroke each year, have better outcomes than those that treat fewer patients per year.
Researchers found that stress on immune cells and altered metabolism lead to different outcomes in individuals infected with the same virus, with potential targets for new treatments identified. Preventing conditions causing increased stress may also prevent disease from viral infections.
A new therapeutic target for the treatment of Alzheimer's disease has been discovered, with research identifying elevated levels of the protein SFRP1 in the brains and cerebrospinal fluid of patients. Inactivated SFRP1 function prevents disease progression in mouse models.
A new international consensus document provides guidelines for the conduct of magnetic resonance imaging studies after a myocardial infarction. The main outcome measure recommended is absolute infarct size, with scanning timing between 3 and 7 days post-infarction.
Researchers develop a new method to detect rheumatoid arthritis by analyzing hand blood content using infrared spectroscopy. The technique can provide an early diagnosis and assess treatment effectiveness, potentially leading to better long-term outcomes for patients.
Researchers developed a stable cobalt(III)-nitrosyl complex, enabling controlled nitric oxide delivery to cells. This discovery has the potential to greatly impact treatment development for cardiovascular diseases, including vasodilation and enhanced neuroplasticity.
A significant decrease in depression cases was observed after CPAP treatment for sleep apnea in patients with cardiovascular disease. The study found that CPAP treatment had a broader benefit of preventing depression, independent of improved sleepiness.
A Michigan Medicine study found that white women and those with higher education levels are more likely to seek fertility treatment than other groups. Nearly 12.5% of women reported experiencing infertility, but only 33% of those with lower education levels sought care.
A new study proposes a novel, non-invasive test for assessing gut function that may help screen and monitor treatment of gut diseases. The test measures the concentration of gut bacterial products in patient's blood and stool, detecting gut leakage and its potential impact on IBD and other intestinal diseases.
A two-year social marketing campaign in California significantly encouraged more people to seek care for symptoms of mental distress. Exposure to the campaign increased recognition of mental illness and advocacy for those affected.
Researchers found that probiotic bacteria Pseudomonas fluorescens reduces the impact of white-nose syndrome in bat populations about five-fold. The treatment lengthened the amount of time bats stayed in the mine, allowing them to recover from the disease and emerge during spring-time when insects are available.
A new intelligent liver function test has been developed to detect liver disease decades before it can become fatal. The test has shown a 44% increase in diagnosis of liver disease, giving patients earlier access to treatment.
Research highlights patchy care, delayed diagnosis, and lack of guidance for treating first-time manic episodes. Effective treatments are available but often overlooked, exacerbating symptoms and worsening health outcomes.
The Obesity Society has developed two new resources to improve obesity medicine education in medical schools and advanced healthcare providers. The resources include the first set of competencies for caring for patients with obesity and a proposed standard of care for adults with obesity, aimed at enhancing patient care.
The International Association for Dental Research (IADR) and American Association for Dental Research (AADR) honored the legacy of Ricardo Teles in a symposium. The symposium reviewed current knowledge in clinical periodontology, identified gaps in research, and recognized his contributions to advancing the field.
Researchers created a synthetic lubricant that mimics the natural lubricin found in joints, providing a potential cure for osteoarthritis. The synthetic lubricant is being tested in canine clinical trials and holds promise for future human use.
A study in CMAJ provides new insights into the decision-making processes of critical care physicians and families in withdrawing life-sustaining treatments from critically ill patients with severe brain injury. Key findings include the influence of patient circumstances, family wishes, severity and location of the injury, past physicia...
Researchers have developed a human cerebral organoid system, or 'mini-brain,' to study sporadic Creutzfeldt-Jakob disease (CJD) and its subtypes. The model enables evaluation of potential therapeutics and provides insights into human prion disease progression.
A Phase IIa trial found that verinurad with febuxostat significantly reduced urinary albumin-to-creatinine ratio by 39% and serum urate levels by 57% after 12 weeks. The effect was sustained through week 24.
A recent study from the University of Adelaide found that having braces does not necessarily lead to increased happiness or psychosocial outcomes in later life. In fact, people who did not receive orthodontic treatment were significantly more optimistic than those who had braces treatment.
A lack of representation of people with disabilities in the biomedical workforce can lead to limited care improvements. Researchers like Bonnielin Swenor advocate for increased diversity and accommodations to create more inclusive environments.
A study found that brain activity related to auditory perception parallels heart rate, suggesting that stress-induced changes in heart rate may impair auditory perception. Researchers suggest that vagus nerve activation by electrical stimulation could improve auditory perception and treat attention and communication disorders.
A study found that four out of five people with Functional Neurological Disorder (FND) experience lasting physical difficulties, with 80% still having symptoms in their arms and legs 14 years later. Doctors are urged to provide realistic prognoses and encourage targeted treatment for patients.
Researchers track early stages of alpha-synuclein protein aggregation in Parkinson's disease, which can lead to significant delay in disease progression. The study's novel method using super-resolution microscopy and advanced analysis has the potential to detect disease progression before symptoms appear.
A new study published in Alimentary Pharmacology & Therapeutics found that gastric bypass surgery improves acid reflux symptoms in most patients shortly after surgery. However, symptoms often return within 2 years, especially in women and older individuals with other medical problems.
Researchers at the University of Saskatchewan found that low-frequency magnetic stimulation improved cognitive and motor function in rodents with concussions. The therapy also protected the brain from future degeneration and restored normal sleep patterns.
A study by Children's National Hospital found that only 54.1% of teenagers diagnosed with chlamydia or PID filled their prescribed antimicrobial treatments, highlighting barriers to treatment adherence for this high-risk population.
A global registry demonstrates FFR provides valuable additional information after angiography, resulting in treatment changes in over a third of patients. The study showed more patients were assigned to medical management and CABG post-FFR than post-angiography.
A review of 52 studies involving 13,000 elite athletes found stigma was the main barrier to seeking help, with poor understanding of mental illness, busy schedules, and gender stereotyping also playing a role. Coaches and sports governing bodies are key to changing the culture and promoting mental wellbeing.
Spatial neglect affects over half of stroke survivors, causing functional disability and poor motor recovery. Implementing a care pathway can improve outcomes by incorporating assessment and treatment options.
Children with protruding teeth are at a higher risk of damage, but regular check-ups can reduce this risk. Early identification and protection through braces and good oral habits can prevent long-term dental issues.
A new study finds that routine sickle cell disease screening among migrants can help prevent severe complications and death. Researchers estimate that up to 80% of newborns with SCD are born in sub-Saharan countries, where the condition is highly prevalent.
University of Kansas researchers have secured a $1.7 million grant to develop an eating disorder screening tool for the military and Veterans Affairs. The project aims to identify organizational barriers to detecting and treating eating disorders, which can have a high mortality rate among mental health disorders.
Researchers at Drexel University found that adults with mental health needs are more likely to receive care and have lower out-of-pocket costs when covered by Medicare or employer-sponsored health insurance compared to ACA Marketplace plans.
Researchers at Osaka University developed a fully automated tool to assess α-synuclein aggregation in cerebrospinal fluid using ultrasonication. The HANABI device can accurately detect patients with Parkinson's disease and has potential for early diagnosis and treatment assessment.
Researchers at the University of Pittsburgh are developing a novel repair device for pelvic organ prolapse (POP) designed specifically for the vagina. The device aims to improve treatment outcomes while minimizing complications, addressing issues that negatively impact women's quality of life.
A new study found that closely monitoring patients with diabetic macular edema who have good vision can be an acceptable initial strategy, with prompt treatment starting if vision worsens. The two-year study showed similar visual acuity outcomes among groups receiving aflibercept injections, laser photocoagulation, or observation.
A new study found that nasal high-frequency oscillatory ventilation (NHFOV) is superior to nasal continuous positive airway pressure (NCPAP) in preventing reintubation in preterm infants with neonatal ARDS. NHFOV reduced PCO2 levels and enabled infants to leave the hospital in fewer days.
A new study finds that starting treatment before vision loss is unnecessary for most people with diabetic macular edema. Close monitoring of the condition is essential to determine when treatment should begin.
The Center for Translation Neurotrauma Imaging (CTNI) aims to pioneer biomarkers, diagnostics, and therapeutics for neurodegenerative diseases. The facility will create novel brain imaging techniques to track subtle changes in the brain after neurotrauma.
A recent study published in the American Heart Association's journal Hypertension found that patients with type 2 diabetes who received intensive blood pressure treatment had lower rates of heart attacks, strokes, and other complications. This benefit was observed regardless of a person's preexisting cardiovascular risk level.
Professor Keith Mathieson's appointment will enhance his research into technologies interfacing with the brain to advance treatments for brain disorders, dementia, and sight loss. He aims to develop a retinal prosthetic device capable of restoring near-normal vision to patients with degenerative retinal conditions.
From 1998 to 2015, US spending on outpatient care for depression increased by 43%, primarily due to expanded insurance coverage for mental health conditions. The study analyzed national survey data and found a significant association between increased healthcare spending and improved mental health treatment outcomes.
A new study published in Medical Acupuncture found that acupuncture significantly improved psychological and pain symptoms associated with post-traumatic stress disorder (PTSD) following a natural disaster. The treatment was effective in reducing symptoms without any serious adverse effects.
A majority of US states restrict decision-making for incapacitated pregnant women, with 25 laws invalidating advance directives during pregnancy. Thirty-eight states have laws that identify pregnancy as a condition affecting decisions for incapacitated women, but these laws vary widely in content.
A comprehensive study tracking 26 years of waste disposal reveals that most oil and gas waste from Pennsylvania stays within the state, posing human health hazards. The study also found that conventional drilling operations accounted for nearly one-third of all waste.
Researchers at Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a protein that causes intestinal permeability in NEC, which can lead to sepsis or death. Inhibiting a special molecule called ROCK may prevent this process, offering a new potential treatment strategy.
Treatment at Canada's only early intervention program for youth with mood and anxiety disorders leads to improved symptoms, functioning, and access to psychiatric care in the most appropriate settings. Patients who disengage from treatment have less severe symptoms than those who stay engaged.
Researchers at Hiroshima University Hospital have developed an oral appliance to treat mild to moderate sleep apnea. The treatment, which brings the jawbone forward to enlarge air passageways, was found to halve sleep apnea episodes and widen airways in a study of 13 patients.
The Louisville Metropolitan Sewer District and Tetra Tech won the 2019 INFORMS Edelman Award for their successful implementation of Csoft, a software solution that maximizes storage, conveyance, and treatment capacities to better protect the environment. The project has saved over $200 million in infrastructure costs and improved commu...
A study highlights the importance of seeking prompt medical advice if symptoms of rabies are suspected, as delays can be fatal. Experts stress that preventive treatments are highly effective when given promptly after exposure, and encourage individuals to seek treatment immediately after a bite or scratch from an animal.
A digital parent training intervention with telephone coaching was successfully implemented in primary health care, reducing discontinuation rates by nearly half. The programme improved parenting skills and satisfied parents, highlighting the potential of web-based interventions to facilitate better access to mental health services.
The REHEAL Glove is a flexible wound dressing that provides negative pressure therapy and allows early motion therapy during healing. It has successfully completed another key step on the road toward commercialization, earning national recognition for its potential to improve treatment of hand trauma.
The Society for Maternal-Fetal Medicine has released new guidelines for diagnosing and treating sepsis in pregnancy, emphasizing the importance of early recognition and management. The recommendations are designed to improve care and prevent organ damage caused by sepsis, with a focus on increasing maternal survival rates.
Despite improvements in heart attack and heart disease care for older women, black women continue to face significant racial disparities in treatment. Postmenopausal black women were 50% less likely and Hispanic women 16% less likely to receive treatment when arriving at the hospital with symptoms compared to white women.
A team of researchers at Cardiff University has discovered that a family of lipids contribute to the development of abdominal aortic aneurysm by driving clotting in blood vessels. The findings suggest new treatments for this potentially life-threatening condition by regulating blood clotting.
A recent study found that patients with lung disease bronchiectasis often display sensitivity to airborne allergens, with a particular role for fungi. The discovery highlights the importance of examining bronchiectasis patients for allergies, as existing treatments can prevent worsening of the disease.
A new study in the Journal of Humanistic Counseling found strong relationships between ecowellness measures and overall wellness among participants aged 19-84. Counselors can integrate this research by asking clients about ecowellness and incorporating nature-based activities into treatment plans to help them feel effective and whole.
A Rutgers University study finds that religious beliefs and cultural values discourage Latinos from seeking treatment for depression and other mental health disorders. The research suggests that engaging with faith-based organizations is crucial to addressing the associated stigma and encouraging people to seek help.