Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
A systematic review and meta-analysis published in JAMA Internal Medicine found that intensive blood pressure lowering treatment does not reduce death or cardiovascular disease in healthy individuals with a systolic blood pressure below 140mmHg. Treatment's beneficial effect is limited to trials in people with coronary heart disease.
A new study found that hospitalized heart failure patients have lower survival rates and higher re-hospitalization risks despite normal left ventricular ejection fractions, highlighting the need for better treatments and outcomes prediction methods.
The American Academy of Ophthalmology and Research to Prevent Blindness announce a new grant opportunity to support researchers using the IRIS Registry database for population-based studies in ophthalmology and blindness prevention. The grants will help advance patient care by leveraging big data analytics.
A study suggests that odor identification tests can identify patients with mild cognitive impairment who may benefit from cholinesterase inhibitor treatments. Short-term improvements in smell identification scores predicted longer-term cognitive improvement with donepezil treatment.
Researchers at UCR and UPenn used microscopy to study blood clot contraction, revealing a novel function for filopodia in clot shrinkage. The findings could aid in the development of new therapies for clotting disorders.
MossRehab's Drucker Brain Injury Unit and MRRI have been recognized for excellence in TBI treatment and research. The facility has continuously funded research on outcome prediction and treatment since 1997.
Researchers from NIAID and University of California, Berkeley develop a cell phone-based videomicroscope that provides fast and effective testing for L. loa parasites in blood samples, allowing dually-infected patients to be protected from ivermectin complications.
A new study published in Frontiers in Medicine found that patients who drink alcohol or smoke are more likely to experience dental filling failure. Genetic differences were also discovered to be associated with increased filling failure rates, suggesting personalized treatments could lead to improved outcomes.
A study by Ohio State University found that upwardly mobile blacks and Hispanics experience more racial discrimination than their socioeconomically stable peers. This discrimination may be linked to poor health outcomes among young adults of color. The research suggests that addressing poverty alone is insufficient to eradicate health ...
The DKCRUSH-V trial found that the double kissing crush two-stent technique resulted in a lower rate of target lesion failure compared to provisional stenting at one year. The study also showed improved outcomes for patients with true distal left main bifurcation lesions.
A new study found that half of UK adults (48%) admit to missing at least a quarter of their teeth while brushing. The survey also shows a lack of guidance on tooth brushing habits, with six in ten adults having never been shown how to brush correctly by a dentist or hygienist.
Eating high-pesticide residue fruits and vegetables was associated with lower probabilities of pregnancy and live birth following infertility treatment. The study found no negative association with low-pesticide residue intake, suggesting a possible link between pesticide exposure and decreased fertility outcomes.
A study from the University of Sydney reveals that men with depression are not engaging with treatment as much as expected, despite increased help-seeking behavior. The research highlights the need for more structured and goal-oriented approaches in treatment regimens to better support men's mental health needs.
Researchers at Bielefeld University developed Narrative Exposure Therapy (NET), a successful treatment method for refugees with mental problems. The therapy involves storytelling to process traumatic events in a meaningful context, leading to closure and reduced symptoms.
A 5-year NYU Dentistry-funded study will compare two cavity-prevention techniques in six rural New Hampshire counties, aiming to reduce oral health disparities. The research will assess the effectiveness of simple and complex treatments.
The FRAX calculator has been widely adopted globally, helping clinicians make informed decisions based on multiple scientifically validated risk factors. A recent study confirms that intervention thresholds based on fracture probabilities are highly effective in targeting high-risk individuals.
A new study suggests that increased screening by primary health care providers is yielding a bigger proportion of diagnoses, leading to more opportunities for treatment. The study found that the proportion of missed cases of diabetes dropped significantly over time, from 16.3% to 10.9%, and targeted screening in high-risk populations c...
The IOF Compendium documents the growing global burden of osteoporosis, with projected increases in fractures expected to pose a huge challenge on healthcare systems. The report outlines eight priority actions to stem this burden, including provision of Orthogeriatric and Fracture Liaison Services.
A growing number of non-resident patients are seeking in vitro fertilization (IVF) treatment in the US, with a significant increase in egg donation and gestational carrier use. The study highlights challenges in accessing high-quality ART care, particularly for patients from countries with restricted payment for egg donors.
Patients who experience negative symptoms during biosimilar treatment attribute them incorrectly to the new medication. Effective communication between clinicians and patients is crucial for successful transitioning.
Experts warn that new NHS rules charging overseas visitors could compromise patient safety and should be withdrawn until a thorough impact assessment is carried out. The proposals pose significant challenges for healthcare teams in establishing entitlement to care and may lead to treatment being refused if patients cannot pay.
Renowned cardiologist Elazer Edelman, MD, PhD, will be recognized for his contributions to the development of coronary stents and vascular disease research. He has authored nearly 300 scientific publications and mentored over 350 graduate students.
Dr. Alec Vahanian, MD, is recognized for advancing the field of interventional cardiovascular medicine through technical expertise and innovation. He has performed pioneering procedures, including percutaneous mitral commissurotomy and transcatheter aortic valve replacement.
Researchers aim to discover whether acupuncture can treat vulvodynia, a women's chronic pain condition affecting up to 14 million Americans. Acupuncture has shown promise in reducing pain in various studies.
Web-based treatments have been found to significantly increase employment rates among individuals with severe mental illness. The studies show that participants worked for three times the number of hours and earned almost $2000 more than the control group.
A new Oxford study reveals that cultural and moral acceptance of assisted reproductive technologies (ART) play a significant role in their usage across Europe. The study found that countries with more accepting attitudes towards ART reported higher rates of usage, regardless of economic factors.
LSU Health New Orleans' Precision Medicine team will participate in the National Institutes of Health's All of Us Research Program, aiming to gather information from 1 million or more participants. The program seeks to design individualized approaches to disease prevention and treatment using diverse data sets.
A new study published in Brain Behavior and Immunity appears to challenge the theory that microglia play a role in fetal alcohol spectrum disorders (FASD). The research found no difference in microglial activity between mice exposed to alcohol early in development and healthy animals.
Researchers have developed a minimally-invasive bioengineered material called RTG to cover neural tube defects in utero, offering an earlier gestational age approach to spina bifida repair. The study demonstrates the feasibility and potential of this alternative treatment method.
The Joslin Diabetes Center has been awarded $8.2 million from the National Institutes of Health (NIH) in continued support for its Diabetes Research Center program. The funding will enable researchers to advance treatments and potentially find a cure for diabetes.
The NIAAA Alcohol Treatment Navigator offers a comprehensive strategy to help individuals search for professionally-led, evidence-based treatment. The navigator guides users through a step-by-step process to find qualified treatment providers, taking into account individual needs and preferences.
A recent study by Mayo Clinic found that nearly 40% of physicians hesitate to seek mental health care due to concerns about their medical license. The researchers discovered that states with licensing requirements asking about past mental health conditions have more reluctant physicians.
A pilot program in five North Carolina schools reduced absenteeism among first- and second-grade students by an average of 10%. The Early Truancy Prevention Program, which involved teachers visiting homes to establish a positive connection with parents and students, showed strong evidence of effectiveness.
Researchers at Monash University have discovered the presence of regulatory T cells in the retina, a potential target for treating retinopathy of prematurity. The study's findings suggest that boosting these cells may repair damaged blood vessels in the retina, reducing ROP risk.
Researchers found that transcranial electrical stimulation significantly improved neural function in participants with mild traumatic brain injury, as shown by reduced abnormal slow-waves in MEG scans. The treatment also led to a significant reduction in post-concussion scores.
A new study from Harvard T.H. Chan School of Public Health reveals that extracellular vesicles (EVs) can carry receptors for intercellular communication, allowing signaling without direct cell-to-cell contact. This capability makes EVs uniquely suited to be engineered to send therapeutics directly to affected areas.
Researchers found that injecting interleukin-27 (IL-27) into mice after a hemorrhagic stroke helped them recover and had less brain damage. IL-27 may play a critical role in protecting the brain from stroke-induced damage, offering new avenues for stroke treatment strategies.
A NYU College of Dentistry team will compare the effectiveness of two cavity-prevention techniques in elementary schools in the Bronx, with a focus on improving oral health equity. The five-year study aims to determine the most effective school-based prevention methods and their impact on quality of life and student achievement.
Intra-articular corticosteroid injections provide effective short-term pain relief and improved function for patients with low-grade knee OA. Maintaining a healthy weight and engaging in physical activity can also help manage symptoms, potentially delaying the need for surgery.
A new tablet-based technology uses video monitoring to detect atrial fibrillation (afib), a condition that affects over 3 million Americans. The system, which requires no user action, will be compared to the gold standard ECG patch in a clinical trial to determine its accuracy.
A new study found that adults with lower education levels and no partner are less likely to regularly check their blood pressure at home. This is associated with a higher frequency of home monitoring among those with high blood pressure who are aware of it and being treated.
A new biomarker, LRG1, can predict the occurrence of pre-eclampsia in pregnant women with type 1 diabetes, increasing their risk by 4 times. The study found that LRG1 levels were significantly higher in women who developed PE compared to those who did not.
Researchers have created an engineered form of ADAMTS-13 (BAX 930) to restore the missing enzyme in patients with congenital thrombotic thrombocytopenic purpura (TTP), a rare and life-threatening blood disease. The therapy was found to be safe and effective, with no allergic reactions or serious adverse events.
A new, fast, and affordable tuberculosis test has been developed for resource-limited areas, enabling early diagnosis and treatment. The paper-based device uses gold nanoparticles and single-stranded DNA to detect Mycobacterium tuberculosis bacteria.
Researchers found brain activity abnormalities persist even after seizure treatment, potentially underlying cognitive problems in children with absence epilepsy. This discovery suggests using EEG tests to diagnose and monitor attentional deficits in epilepsy patients.
Research finds that women with asthma are more likely to receive fertility treatment, suggesting improved asthma control may enhance pregnancy. The study's findings do not prove a causal link but encourage future investigations into the relationship between asthma and fertility.
Researchers evaluate innovative treatments for common emotional problems after TBI, including videoconferencing technology and web-based interventions. Participants show significant improvements in emotional regulation, positive emotions, and problem-solving skills.
Research in the UK found that people with disabilities face significant hurdles accessing healthcare services, with disabled women being disproportionately disadvantaged. Long waiting lists and cost of treatment were major obstacles, affecting over one-fourth of those with severe disabilities.
Researchers developed a predictive model of inflammatory bowel disease by integrating DNA variation, gene expression, and clinical information. The model identifies key regulators of the immune component and may lead to new treatments for patients.
A multicenter trial found that endobronchial valve treatment improves lung function, reduces shortness of breath and exercise intolerance, and increases quality of life in patients with severe heterogeneous emphysema. The treatment has been shown to be safe and effective for appropriately selected patients.
Researchers at the A.J. Drexel Autism Institute are studying the benefits of early detection of autism through a $11.4 million grant from the National Institutes of Health. Early detection is critical for improving outcomes in social and cognitive functioning, as well as mitigating disabilities over a child's lifetime.
Researchers explored non-thermal atmospheric pressure plasma treatment to improve natural dyeing of leather, reducing environmental impacts. The study successfully demonstrated the activation of functional groups on goat hide surfaces, leading to significant improvements in coloration with commercially available natural dyes.
A post-hoc analysis of the SPRINT trial suggests that a universal blood pressure target may not be suitable for all patients. For those with high systolic blood pressure readings, intensive treatment might not always be beneficial, and the harms of aggressive treatment could outweigh the benefits.
A 3-year follow-up study shows that a short course of dual antiplatelet therapy is as beneficial as a longer course for patients who received a drug-eluting stent. The study found no significant differences in rates of cardiac events and major bleeding between those treated for 6 versus 18 months.
Nonagenarian patients undergoing TAVI had worse short-term outcomes but similar one-year clinical outcomes as younger patients. The study suggests that TAVI is safe and effective in elderly patients with aortic stenosis.
A new concept of nonvoluntary treatment could distinguish psychiatric patients who refuse help but likely would have accepted it in a healthy state of mind from traditional involuntary treatment. This distinction aims to provide more precise categorization and alleviate ethical concerns.
Researchers found that chronic tinnitus is associated with changes in certain networks in the brain, leading to increased attention and reduced rest. The study provides hope for future treatment options and validates patients' experiences.
A recent study from North Carolina State University found that 21 percent of mothers experiencing postpartum mood disorders do not disclose their symptoms to healthcare providers. The study suggests that support networks and normalizing mental health discussions are key to addressing this issue.
A new study has found a significant link between malnutrition and tuberculosis (TB) in southern India. The research, published in PLOS ONE, reveals that more than 61% of TB cases in women are attributable to malnutrition, while up to 75% of male TB cases could be eliminated if alcohol use was reduced.
A study of healthy young men found that brain reward system activation dips at 2 p.m., contrary to previous research showing peak mood during this time. This timing may impact the treatment of disorders like depression, substance abuse, and sleep disturbances.