Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Researchers have successfully used an artificial womb to incubate healthy baby lambs for a week, paving the way for potential treatment of extremely premature infants. The technology, known as ex-vivo uterine environment (EVE) therapy, aims to improve lung development and reduce ventilation-derived injury.
A new study published in the Journal of Neurosurgery found that smoking significantly increases the chance of brain aneurysm recurrence. Former and current smokers had a higher rate of recurrence compared to never smokers, emphasizing the importance of quitting smoking after endovascular treatment.
Subarachnoid hemorrhages account for 5-10% of all strokes, particularly among younger patients, and can result in long-term neuropsychological effects. Expert treatment is crucial, with high-volume centers and specialized neurosurgeons offering the best outcomes.
A study by Martin-Luther-Universität Halle-Wittenberg and BRAIN AG found a clear correlation between sugar consumption and dental illness, resulting in significant costs. The researchers estimated that implementing the World Health Organization's 50g sugar per person per day target could save Germany up to 12 billion euros annually.
A study co-led by John H. Martin found that genetic mutations in the Bax/Bak pathway affect neural motor skills development in infant mice. The researchers discovered that disruptions in this pathway hinder the formation of proper connections between the brain's motor cortex and spinal cord.
A team of researchers at FAU has identified a key mechanism involved in the resolution of inflammations in rheumatoid arthritis patients. Innate lymphoid cells can induce a 'hibernation' state, which persists in those with rheumatism but is reversed when these cells are 'woken up', stopping inflammation and joint damage.
Individuals with eating disorders are more likely to be convicted of theft and other crimes, with 12% and 7% incidences reported. Researchers call for further investigation into the relationship between crime and eating disorder psychopathology.
A systematic review found that lifestyle-modification programs have no significant impact on body weight in Arab countries, highlighting the need for adapted treatment programs. The studies cited methodological flaws, including linguistic and socioeconomic context neglect, and sociocultural obstacles to female participation.
A new automated system for measuring nighttime oxygen levels could help diagnose sleep apnea in children who snore. The approach was most accurate for children with severe apnea and detected 90% of those with severe disease. The test is simple, inexpensive, and can be performed at home using a pulse oximeter.
Researchers have identified a novel botulinum neurotoxin, BoNT/X, with potential to treat various medical conditions, including muscle spasms and chronic migraine. The discovery enables the development of diagnostic methods and treatments, facilitating countermeasures against exposure to toxic amounts of the substance.
Bystanders can make a difference in acid attacks by removing contaminated clothing and washing off acid with water. Public education and clear guidance for health professionals are also crucial to limit long-term physical and emotional effects.
In the wake of Charlie Gard's high-profile court case, Professor Dominic Wilkinson emphasizes the need for fair, accurate, and balanced discussion in cases involving life-prolonging treatment. One potential solution is to allow medical professionals to make public the medical evidence on which they are basing their decisions.
A study found that steroid treatment for IgA nephropathy was associated with a significantly higher risk of serious adverse events, primarily infections. The trial was stopped early due to an unexpectedly high rate of serious infections and two deaths.
A new study published in CMAJ found that people who survive a stroke or mini-stroke without early complications have an increased risk of death and stroke for at least 5 years following the initial event. Researchers recommend long-term management of modifiable risks, such as high blood pressure and physical activity, to reduce this risk.
A major scanning study identified changes in white matter of the brain in people with depression, shedding light on the biology of the condition. The study used a cutting-edge technique to map brain structure and found reduced white matter integrity in those reporting depressive symptoms.
A study found that 67% of pet owners surveyed couldn't accurately recognize veterinary emergencies, with many calling out-of-hours services for convenience or reassurance. Veterinary practices can help by providing guidance on emergency conditions and training receptionists in telephone triage.
Researchers found that patients appreciate being able to confirm next steps, feel heard and gain confidence in providers through secure access to visit notes. Patients also value the ability to provide feedback on accuracy and catch potential errors.
The symposium, The Architects of Aging, brings together leaders in biotechnology and biomedical research to target the underlying mechanisms of aging. Experts will present cutting-edge interventions that aim to modify biological processes of aging, with a focus on extending healthspan.
Researchers at the University of Missouri-Columbia found that diet is not a contributing factor to gastrointestinal issues in children with autism spectrum disorder. Stress, rather than nutrition, appears to be a major contributor to these symptoms.
Research found that reduced mastication in mice led to suppressed maxillofacial bone and muscle growth, as well as reduced neural activity in the hippocampus, a key component of memory. This study suggests maintaining or strengthening masticatory function may help prevent dementia and memory/learning dysfunction.
The Wyss Center is working on a $19M project to develop a high-resolution, implantable neural interface network that can record and stimulate neural activity. The system, dubbed 'neurograins', aims to provide new treatments for sensory deficits and monitor physiological parameters in real-time.
A family-based treatment approach for childhood obesity was found to be effective in reducing body mass index standard deviation scores. Young age and high BMI-SDS at baseline, as well as good motivation for treatment and adherence to the protocol, were key factors associated with successful weight loss.
The National Institutes of Health (NIH) has renewed funding for the University of Pittsburgh's Cardiovascular Bioengineering Training Program, which educates students in cardiovascular research and prepares them for careers in basic and translational cardiovascular research. The program focuses on three areas: understanding native and ...
Researchers at the University of York have found that parasites responsible for leishmaniasis are mainly acquired from the skin rather than through blood transfusions. This discovery challenges current treatment methods and highlights the importance of measuring parasite levels in the skin to assess treatment success.
A large nationwide study involving over 40,000 women found that fertility treatment does not increase the risk of divorce. The study, which followed couples for 16 years, revealed that the majority of couples had children with their baseline partners and around one-fifth ended up separated or divorced.
Researchers found no significant difference in pain intensity after radiofrequency denervation, a procedure that uses electric current to target nerve pain sources. The study involved 681 participants and included three randomized clinical trials assessing the effectiveness of the treatment for different types of low back pain.
Two studies published in JAMA found that electroacupuncture improved symptoms of stress urinary incontinence, with effects persisting beyond treatment. However, acupuncture did not increase the likelihood of childbirth among women with infertility, suggesting further research is needed to understand its long-term efficacy.
A study reveals the importance of formal education, screening, and treatment protocols for emergency department personnel in identifying and rescuing human trafficking victims. The project increased the identification of other forms of abuse, such as domestic violence and sexual assault.
Neurologists and neurotraumatologists review the science of concussions and outline areas where neuroscience and clinical research can help create consensus. They emphasize the importance of diagnosis in treatment and suggest using animal models to discover better treatment plans.
Children with TB meningitis have a unique biological profile that helps assess disease severity and predict outcomes. This discovery enables doctors to make informed treatment decisions and provide novel treatments.
The EHRA White Book provides comprehensive data on cardiac arrhythmia treatment, including device implantations and interventional procedures. The 2017 edition shows significant disparities in treatment across countries, with higher volumes of device implantations in Western and Northern countries.
A study of refugee youth found distinctive patterns of symptoms, including traumatic grief, phobia, and somatization. The findings highlight the need for specialized treatment approaches that address the unique experiences of displaced youth.
A study found that telemedicine treatment was not inferior to traditional office visits for non-acute headaches. The researchers also assessed the safety of using telemedicine and found only one missed diagnosis in each group, estimating a 20,200 consultations-to-diagnosis ratio.
A new statistical analysis rebuts a previous study claiming a link between declining inpatient beds and increased suicide rates. The authors suggest focusing on proper diagnosis and treatment of depression and training primary care physicians to screen patients for mental health care.
A study found that patients with primary Sjögren's syndrome are 11 times more likely to have had a prior nontuberculous mycobacteria (NTM) infection than controls. NTM infection was also linked to increased risk of developing the disease, particularly among those aged 45-65 years.
A meta-analysis published at EULAR 2017 found that early treatment of pre-rheumatoid arthritis (pre-RA) significantly reduces the risk of developing rheumatoid arthritis (RA). Patients who received active treatment had a lower risk of RA at 52 weeks or more compared to those on placebo.
A new study published in Radiology found that uterine fibroid embolization (UFE) can help restore fertility in women with uterine fibroids. After an average follow-up of six years, 41.5% of women who underwent the procedure became pregnant and gave birth to 150 babies.
A large research study reveals that older people are not being referred for mental health support nearly as frequently as their younger counterparts. Despite this, studies have shown that older people may benefit the most from 'talk therapies', with over three-quarters of people around the age of 64 experiencing significant clinical im...
The European Society of Anaesthesiology and Intensive Care proposes new guidelines for in-flight cardiac arrest, highlighting the importance of emergency equipment and crew training. The guidelines aim to improve treatment recommendations and reduce fatalities in such cases.
A study found that 74% of bed partners encouraged early bedtime or late wake times, which conflict with cognitive behavioral therapy for insomnia. Partners also made accommodations that affected their own functioning, leading to increased anxiety.
ECHO Autism program trains primary care providers to diagnose and manage autism spectrum disorders, improving confidence and access to care for children with autism in rural areas. The program's expansion aims to bridge gaps in healthcare for underserved communities worldwide.
A randomized clinical trial found that parent-based weight loss treatment (PBT) with or without child attendance resulted in similar weight loss outcomes, including decreased BMI z scores and improved calorie intake and physical activity. The study suggests that child attendance at treatment is not necessary to achieve similar outcomes.
A new study suggests that bouldering may be used to effectively treat symptoms of depression, with participants who immediately began the intervention showing a 6.27-point improvement in depression scores compared to those who waited, improving from moderate to mild depression levels.
A comprehensive medical weight-loss program showed no significant difference in one-year weight loss outcomes between patients with insurance coverage and those who paid out of pocket. However, insurance-covered patients had slightly lower dropout rates compared to self-paid individuals.
Dr. Randy McIntosh's team developed the Virtual Brain Project, an integrated computer model of a fully functioning human brain to help detect dementia and brain diseases earlier. The platform allows for testing potential treatments before prescribing them to patients.
A new paper-based test strip could enable doctors and patients to monitor heart failure conditions at home, using smartphone apps for analysis. The test strip detects antigens ST2 and BNP, providing insights into the progression of the disease.
The EURO-CTO trial found that PCI had a higher procedural success rate (86.3%) and lower procedural risk compared to optimized medical therapy. Patients treated with PCI also showed significant improvements in clinical symptoms and quality of life, while those on medical therapy experienced less pronounced improvements.
A randomized study found that group-based quality improvement sessions improved TTT scores from 11% to 57% in intervention patients, while control patients saw a decline to 25%. The learning collaborative positively impacted implementation of the recommended care approach.
The University of Colorado Anschutz Medical Campus has received a $47.8 million gift to establish the Marcus Institute for Brain Health and build a network of mental health clinics across the US. The Cohen Veterans Network will partner with CU Anschutz to provide free, low-cost care to veterans and their families.
A recent study published in JAMA Neurology found that US military service members who experienced a mild concussion after blast injury may continue to experience mental health symptoms and decreased quality of life for at least five years. The study also highlights the need for more effective, long-term treatment strategies.
Researchers found that breathing low-oxygen air reversed brain damage caused by mitochondrial defects in mice. The study suggests that hypoxia therapy may be a potential treatment for mitochondrial diseases, including Leigh syndrome. Further research is needed to confirm these findings and develop a practical regimen.
A new interactive website, Balance Retraining, has been developed to help people with dizziness carry out vestibular rehabilitation exercises via the web. The site provides personalized feedback and advice, and has shown promising results in reducing dizziness symptoms amongst adults aged 50 and above.
Researchers found that resveratrol supplementation reduced aortic stiffness by up to 9.1 percent in patients with high arterial stiffness, but the effect was not significant in those with normal aortic stiffness. Resveratrol may activate the longevity gene SIRT1 as a potential mechanism for its effects.
Two effective parent-involved therapies, group therapy and individual parent behavior therapy, show best results in treating children with disruptive behavior disorders. These therapies empower parents to be their child's best advocate and guide their behavior.
The Heinz C. Prechter Bipolar Research Program has received a $5 million gift commitment from the World Heritage Foundation - Prechter Family Fund, which will double donations to bipolar disorder research. The program aims to identify effective solutions for people with bipolar disorder through long-term studies and DNA analysis.
A new study reveals a significant increase in telemedicine visits for mental health disorders in rural areas, with an average 45% jump per year between 2004 and 2014. However, the distribution of these services is uneven across states, with some having no visits in 2014.
A new classification system identifies distinct patient profiles with varying outcomes in acute heart failure hospitalizations. The study provides valuable insights for early triage and treatment decisions.
A multifaceted intervention lowered the relative risk of new suicide attempts by 20% in emergency department patients who received specialized screening, safety planning guidance, and periodic follow-up phone check-ins. Patients in the intervention group made 30% fewer total suicide attempts compared to those receiving standard ED care.
A research team has identified a key molecular target that regulates antibody production in both helper and regulatory T cells, which may lead to the development of new treatments for autoimmune diseases like lupus and rheumatoid arthritis.
Boston University School of Medicine's team science approach has led to numerous publications, new research grants, and training opportunities. The Evans Center for Interdisciplinary Biomedical Research has facilitated successful biomedical partnerships, resulting in 421 highly cited scientific publications.