Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Carnegie Mellon University's Rob Kass and Byron Yu will present on using statistical methods to understand brain function, including the development of brain-computer interfaces. The panel aims to explore the application of cutting-edge statistics in neuroscience.
A new study published in the European Heart Journal found that every ten-minute delay in treatment for STEMI patients with cardiogenic shock results in an extra 3.3 deaths per 100 patients treated with PCI. Treating STEMI patients within 90 minutes of first contact can prevent one death in every 12 patients.
Researchers have identified activation of nitric oxide-dependent endothelial function as the key to losartan's anti-aortic root remodeling activities. This finding challenges traditional views on blood pressure control in Marfan syndrome treatment, suggesting a new approach focusing on endothelial function may be more beneficial.
A University of Missouri study found therapeutic horseback riding to be a clinically effective intervention for alleviating PTSD symptoms in military veterans. Participants experienced a significant decrease in PTSD scores, dropping by 67% after three weeks and 87% after six weeks.
Researchers have identified a method to prevent posttraumatic osteoarthritis (PTOA) by reducing oxidative stress after fractures in an animal model. By inhibiting mitochondrial metabolism or boosting antioxidants, they demonstrated that PTOA can be significantly blunted.
A six-year study found that cognitive enhancement therapy (CET) significantly improved neurocognitive function in adults with autism, particularly in attention and social understanding. In contrast, enriched supportive therapy (EST) showed slower but still significant improvements in social cognition.
NAD+ supplementation improves cognitive function, reduces DNA damage and neuroinflammation in AD mouse model with DNA repair deficiency. Researchers report promising results with potential implications for Alzheimer's disease treatment.
A recent study published in the Journal of Epidemiology and Community Health found that people with anxious personalities are more likely to be bitten by dogs. The survey revealed nearly three times the actual number of dog bites as hospital records indicate, suggesting a higher risk for anxious individuals.
The University of Texas at Arlington has received a $227,000 grant to develop the manufacturing process for the REHEAL glove, a bioengineered healing glove that delivers medicine to injured hands to speed up healing. The project aims to accelerate rehabilitation and improve patient care.
A group of molecules called chondroitin sulfate accumulates and causes inflammation in the hearts of patients with heart failure, leading to multi-organ failure. Researchers found that targeting these molecular nets may bring a fresh new treatment approach for patients with severe debilitating disease.
Scientists at Queen Mary University of London have successfully generated an artificial adrenal gland using cells derived from urine. The new approach uses reprogramming to create steroid-producing cells that can model adrenal diseases and test personalized treatments for patients with adrenal insufficiency.
A major study found a significant increase in the number of X-rays given to patients when dentists were paid on a 'fee-for-service' basis, compared to fixed salaries. This increase was most pronounced when patients were exempt from charges.
Researchers at Drexel University found that telling people weight loss is difficult can actually motivate them to shed more weight in the short-term. However, this approach did not lead to long-term changes in unhealthy foods at home. The study suggests that modifying the home food environment, rather than just providing diet advice, i...
A recent study found that changes between interim and final publications of randomized trials can be significant, affecting clinicians' and the public's understanding of treatment benefits. The study analyzed 613 interim publications and compared them with their final versions.
Researchers found that women following a Mediterranean-style diet before IVF had a 65-68% greater likelihood of achieving a successful pregnancy and birth compared to those with the lowest adherence. The study suggests that a healthy diet, such as the Mediterranean diet, may help increase chances of fertility.
The approval of Spinraza marks the emergence of a new class of biological products, following predictable patterns of innovation. Analysis of over 60,000 research publications reveals that successful product development characteristically follows the maturation of enabling research.
Researchers found that each 1-hour delay in treatment reduces the chance of recovery with minimal or no disability by 11 percent. Prompt clot removal through 24 hours can improve outcomes for patients, but the overall effect of treatment declines with time.
The Journal of the American Geriatrics Society article highlights issues in caring for older women's sexual health, including insufficient physician training. Physicians should regularly inquire about sexual activity and function, offering practical advice on common chronic medical conditions and vulvovaginal atrophy.
A new study found that financial barriers may limit willingness to call 9-1-1 when experiencing stroke symptoms in minority neighborhoods. The study analyzed survey responses from Chicago residents and found that ambulance charges may prevent people from seeking timely medical attention.
Researchers have developed a new, expedited course of treatment for combat-related PTSD that is as effective as traditional eight-week therapy. The study found that prolonged exposure (PE) therapy administered over two weeks resulted in significant symptom reduction and remission rates among active-duty military personnel.
A scientifically based CAMBRA model, including risk assessment and aggressive preventive measures, dramatically reduces tooth decay in community dental practices. The study's findings support earlier research and have potential to transform dental care for high-risk patients at lower costs.
A new method, SPADE, can quantify and monitor diagnostic errors in hospitals using large databases and statistical analyses. This approach has the potential to improve patient outcomes by tracking serious adverse events and enabling patient empowerment.
The International Osteoporosis Foundation has published country-specific FRAX-based intervention and assessment thresholds for seven Latin American countries, enhancing fracture risk assessment. The thresholds vary significantly across the countries, emphasizing the need for tailored prevention programs.
A new study has identified protein biomarkers that can help monitor the progression and treatment of Hutchinson-Gilford progeria syndrome (HGPS) in children. The research found levels of more than 40% of proteins to be significantly different in HGPS samples compared to non-HGPS control samples.
Researchers created a robot to aid in treating babies with oesophageal atresia, a rare genetic disease that affects the infant's oesophagus. The robot stimulates cells by gently pulling on tissue using sensors.
A randomized controlled trial analyzed 126 adults with PTSD, concluding that trauma-focused therapy WET was just as effective as CPT in reducing symptoms. The findings have important implications for treating PTSD, addressing a significant barrier to care by identifying time-efficient treatment options.
A study published in the New England Journal of Medicine found that women using IVF have similar chances of having a baby with fresh or frozen embryos. The research, involving 2,157 women, showed no significant difference in live birth rates between the two groups.
An experimental MERS treatment developed from cattle plasma is safe and well-tolerated in a small clinical trial. The treatment, SAB-301, has been successfully tested in mice and shows potential for rapid production of human antibodies against other human pathogens.
A study of 106 counseling professionals found 71% work with clients exhibiting race-based trauma symptoms but only 33% received training on identifying it. Effective treatment models are needed to address racism and racial discrimination.
Researchers have found that patients with Parkinson's disease have more errors in mitochondrial DNA within the brainstem, leading to increased cell death. Surviving cells have higher copies of mitochondrial DNA, suggesting a new target for therapies.
A new device, SPARTAN, uses an obstacle course to select the fastest and healthiest sperm cells for use in IVF treatment. The device can reduce IVF treatment cycles and potentially increase pregnancy rates by selecting sperm with excellent motility, normal morphology, and better DNA integrity.
Researchers have developed a new approach to treating tinnitus by targeting unruly nerve activity in the brain with precisely timed sound and skin stimulation. Human participants reported improved quality of life after four weeks of daily device use, while sham treatment did not produce similar effects.
Researchers have identified a weakness in the lethal fungus Pseudogymnoascus destructans that causes white-nose syndrome. The fungus is highly sensitive to UV light, making it susceptible to novel treatments that could save bat populations.
A UNIST professor has been awarded for his work on a patch that can regenerate damaged spinal cords, with the aim of preventing further progression of damages and optimizing neurogeneration. The patch is currently in Phase III clinical trials and contains FDA-approved materials, showing promising therapeutic effectiveness.
Researchers found a direct link between symptom severity and treatment outcomes in patients with isolated dystonia, using deep brain stimulation. Brain activity patterns reveal disease severity, and oscillatory brain activity in the 'theta band' is associated with dystonic symptoms.
A new study reveals that inflammatory mechanisms in the brain drive Alzheimer's disease progression. The research found a molecular complex of the immune system promotes aberrant aggregation of proteins, including Amyloid-beta, which accumulates in the brain and harms neurons.
A recent study in NeuroRehabilitation highlights the need for better addressing neurosexuality in patients with neurodisabilities, including members of the LGBTQIA+ community. The research provides guidance for healthcare providers and caregivers to improve sexual function and quality of life.
A new study from Oregon State University found that people with rare diseases experience high levels of anxiety, depression, and pain, as well as limited ability to participate in society. The study suggests that psychosocial support is needed to improve quality of life for this group.
Researchers have identified a potential target for treatment to heal damaged blood vessels, which could be administered by paramedics on arrival at the scene. The study found that endotheliopathy occurs within minutes of injury and that improving the lining of blood vessels can reduce rates of organ failure.
A new smartphone app aims to improve treatment outcomes for patients with eating disorders by providing clinicians with real-time feedback on their progress. The app will guide clients through a series of questions using computer-adaptive technology, allowing therapists to track patient response and adjust treatment accordingly.
A new study found that Salmonella typhi toxin targets specific cells expressing multiantennal glycan receptors, which could lead to the development of targeted treatments for typhoid fever. The research also highlights the potential for sugar-based therapeutics to combat antibiotic-resistant diseases.
Dr. Peii Chen has been awarded a $600,000 NIDILRR grant to develop a Virtual Reality Spatial Retraining Therapy (VR-SRT) System to improve rehabilitation outcomes for individuals with spatial neglect after stroke. The therapy aims to be accessible, affordable and flexible, enabling more stroke survivors to access treatment.
New research by the University of East Anglia and Stockholm University found that staff who feel treated unfairly at work are more likely to be off sick for longer periods. The study also discovered that higher levels of job insecurity increase the risk of long-term sickness absence.
A comprehensive new report examines three systems used to understand mental health disorders: ICD, DSM, and RDoC. The report finds that these systems have similarities and differences in how they classify and conceptualize mental disorder, highlighting the need for a nuanced approach that considers individual factors.
Researchers at the University of Nottingham have uncovered the physiochemical 'fingerprint' profile of Necator americanus, a parasitic worm infecting hundreds of millions worldwide. This discovery enables the development of more effective treatments and earlier interventions.
Scientists at USC have developed a temperature-sensitive gel that can seal eye injuries, allowing for faster treatment and reducing the risk of complications. The reversible seal can be easily removed with cool water, making it a promising solution for treating ocular injuries on the battlefield.
A new study reveals that hyperbaric oxygen therapy may correct behavioral and physical deficits associated with Alzheimer's disease. The treatment reduced plaque pathology by 40% and neuroinflammation by about 40%, improving the condition of mice with the disease.
A study published in Obesity found that individuals with Type 2 diabetes and obesity who continue to binge eat while trying to lose weight drop significantly less weight than those who don't or stop binge eating. Researchers recommend targeting treatment for this behavior, such as cognitive behavioral therapy.
Research from Australia's NICM Health Research Institute finds large nutritional deficits in blood levels of critical nutrients among individuals with early psychosis. Vitamin B9 (folate) and D were found to be particularly low, associated with poorer mental health outcomes.
Researchers studied brain activity of patients with PTSD using EEG tests and found enhanced responses to deviant tones, correlating with poorer cognitive performance on memory tests. This study may lead to the development of a new neurobiological marker for PTSD diagnosis and assessment of treatment outcomes.
People born prematurely may experience impaired lung function due to smaller airways. Researchers measured lung function at rest and during exercise to estimate airway size, finding it was smaller in premature groups.
A recent study from the University of Helsinki found that disordered eating among young adults has significant long-term negative health effects, including higher body weight, lower psychological wellbeing, and a lower self-evaluation of general health. Early recognition and treatment are crucial to mitigate these effects.
A new meta-analysis confirms the effectiveness of vaginal progesterone in reducing preterm birth risk and improving perinatal outcomes for women with a shortened cervix. The study found significant reductions in preterm birth rates and neonatal complications, as well as improved childhood neurodevelopment.
A new study found that positive airway pressure therapy significantly improves both general and sleep-specific quality of life measures in patients with obstructive sleep apnea. The improvements were most notable in those who adhered to the treatment.
Experts argue that a non-discriminatory legal framework governing involuntary treatment could replace unjust discrimination against people with mental ill health. Critics, however, worry that changing the law without proper resourced services could lead to reduced rates of compulsion and decreased care for vulnerable individuals.
The UK's National Health Service (NHS) is considering adopting 'accountable care organisations' (ACOs), a US healthcare model that aims to improve care coordination and reduce costs. Experts warn that this change would be a major overhaul of the NHS without proper public consultation.
A study by Aarhus University finds that cognitive behavioral therapy is highly effective in treating OCD in children and adolescents. The research, involving 269 participants from Denmark, Norway, and Sweden, showed that 92% of those who benefited from the treatment remained symptom-free a year after completion.
A new study of patients who underwent laser treatment to vaporize floaters found a very low complication rate and significant improvement in vision. Most patients reported no complications and experienced improved vision after the procedure.
Suture ligation is a common but ineffective treatment for polydactyly, often requiring corrective surgery due to complications such as painful neuromas and infection. Surgical excision is considered a more effective option with fewer risks and less scarring.
Scientists discovered that sensory neurons in the head and face are directly connected to the brain's emotional pathways, explaining why people experience greater fear and emotional suffering from these types of pain. This finding may lead to more effective treatments for chronic headaches and neuropathic face pain.