Articles tagged with Medical Treatments
A new drug, BPN14770, has shown promise in protecting against memory loss and nerve damage associated with Alzheimer's disease. The drug inhibits phosphodiesterase 4D, an enzyme that plays a key role in memory formation and neuroinflammation.
A study found that Native Hawaiians who participated in a hula dance program significantly lowered their blood pressure compared to those who received standard education. The program, which was tailored to the community's cultural values and perspectives, showed promising results in reducing blood pressure and improving overall health.
Dr. Hossein Tavana's research aims to understand the fluid dynamics of surfactant in premature babies' lungs and improve surfactant replacement therapy for RDS. His lab will generate 3D physical models of airways to aid visualization of surfactant flow, leading to better design strategies.
A new study published in Lancet Gastroenterology and Hepatology found that cognitive behavioural therapy (CBT) tailored for IBS can provide effective, long-term relief despite patients having no further therapy. The research indicates that easily accessible treatment could be provided to a large number of patients with IBS.
Researchers discovered a receptor on brain cells that promotes resilience to stress and may be a useful biomarker for post-traumatic stress disorder (PTSD). The sphingosine-1-phosphate receptor 3 (S1PR3) protein was found to be associated with reduced symptoms of PTSD in human patients.
Researchers from The Westmead Institute for Medical Research have discovered how fatty liver disease develops in lean people. Lean patients tend to have worse outcomes due to an 'obesity-resistant' profile, despite having higher levels of bile acids and FGF19, which increase energy expenditure.
A survey of bereaved Danish parents suggests that doctors often inform them of their child's terminal illness too late, with over four in ten saying they were told just hours before death. The study highlights the need for improved education and training for healthcare professionals on how to break bad news to families.
Researchers investigated metabolic changes across organs in a large animal model of sepsis, identifying common and organ-specific alterations that could inform new therapeutic approaches. The study, published in The American Journal of Pathology, has the potential to reduce mortality and morbidity associated with sepsis.
Scientists at MSD and Francis Crick Institute are working together to better understand Motor Neurone Disease, a devastating disease with no current treatments. The collaboration aims to identify key mechanisms that can kill motor neurons and build scientific understanding for future treatments.
Researchers found that remote ischemic limb conditioning increased inflammatory cells in circulation, reducing brain tissue damage and swelling while improving motor function. The technique has potential for treating strokes of varying severity, offering hope for improved recovery outcomes.
A recent study by University of Edinburgh researchers found that nearly 20% of people waiting for hip replacements suffer from extreme pain or discomfort. The study also revealed that knee replacement patients face similar struggles, with 12% reporting severe health issues.
Researchers explore ultrasound therapy's effectiveness in treating various cardiovascular conditions, including hypertension and arrhythmia. The study highlights the benefits of acoustic intervention, including deep tissue penetration and minimal invasiveness.
Researchers are searching for genetic links to stuttering through a global study recruiting Australian stutterers aged seven and older. The study aims to develop treatments targeting the disorder's underlying cause, rather than just symptoms, with potential benefits for better treatment and prevention of stuttering.
Landos Biopharma has completed a $60 million Series B financing round to support global Phase 2 clinical trials of its lead product BT-11 for ulcerative colitis and Crohn's disease. The funding will also advance additional pipeline candidates, addressing an unmet clinical need for new therapies in inflammatory bowel disease.
The All of Us Research Program has made strong progress in advancing precision medicine by collecting diverse participant data. The program aims to include 1 million or more people from diverse communities, with over 230,000 participants enrolled and 80% from underrepresented groups.
A simple, electricity-independent device has been proven effective in reducing child diarrhea rates by up to 23% in developing countries. The Aquatabs Flo technology uses precise chlorine dosing to purify water without compromising taste, offering a promising solution to control the second-leading cause of death for children globally.
Patients transported by mobile stroke unit receive clot-busting procedure an average of 10 minutes faster than standard ambulance, potentially saving up to 270 million neurons per patient. The quicker treatment can restore blood flow and save neurological function.
Researchers found that smoking did not reduce flares, medication use, hospitalizations, or colon surgery in patients with UC. Smoking cessation also did not worsen the course of disease.
A new study suggests that outdoor light exposure may help prevent myopia in children by thickening the choroid behind the retina. The research aims to develop targeted treatment options to slow down myopia progression and improve eye health.
Researchers at Scuola Internazionale Superiore di Studi Avanzati have developed self-standing carbon nanotubes that can modulate the growth and activity of nerve cells. These innovative materials show promise for repairing spinal injuries by creating biosynthetic hybrids.
Researchers found that Edinburgh has the highest rate of inflammatory bowel disease globally, with one in 98 people expected to be affected by 2028. The study highlights the need for more resources to provide patients with research, treatment, and care.
A recent study published in The Lancet found an AI model can identify patients with intermittent atrial fibrillation using a 10-second ECG test. The technology achieved an overall accuracy of 83% and has the potential to aid doctors investigating unexplained strokes or heart failure.
A study found that smoking impairs the effectiveness of embolization treatment for pulmonary arteriovenous malformations (PAVMs) in patients with HHT. Smokers experienced a higher rate of PAVM persistence after treatment compared to non-smokers, with those who smoked more than 20 pack-years facing a fivefold increased risk.
Researchers investigated acupuncture as an added treatment to reduce frequency of angina attacks in patients with chronic stable angina. The study, conducted in China, involved approximately 400 adults and showed promising results for acupuncture as a complementary therapy.
A group of scientists recommends large-scale collaborative research to tackle dry macular degeneration, with proposed methods including integrated collaboration and biorepository development. The panel aims to bring about meaningful clinical results by promoting multidisciplinary investigator teams.
A global study found that EVT decisions differ significantly between regions and specialties under current local resources, but not under ideal conditions. The most important factors for EVT decisions include NIH Stroke Scale score, level of evidence, patient's age, and clinicians' experience in EVT use.
Researchers present a treatment program to guide effective control of sarcoptic mange disease in wombat populations, building on lessons learned from a previous outbreak at Narawntapu National Park. A longer-lasting treatment and improved delivery are proposed to improve capacity for controlling the disease.
A $1,825,742 NIH grant will fund a randomized controlled trial of strategy-based cognitive training in individuals with multiple sclerosis. The study aims to develop a treatment that improves everyday functioning and neuropsychological performance in those affected by the condition.
A new study from Massachusetts General Hospital's Tobacco Research and Treatment Center shows that daily e-cigarette use helps US smokers quit regular cigarettes. Smokers who used e-cigarettes every day were more likely to quit combustible cigarettes within one year and stay quit for at least another year.
A new NIH-funded study suggests that standard treatment of blood sugar levels after acute ischemic stroke is more effective than aggressive methods in improving patient outcomes. The study found that intensive glucose management increased the risk of hypoglycemia and required higher levels of care.
A new study found that cognitive-behavioral therapy (CBT) can be successful for youth with obsessive-compulsive disorder (OCD), regardless of whether they have hoarding symptoms. The presence of hoarding symptoms did not negatively impact treatment response to CBT in children and adolescents.
A study by the University of Göttingen found that in the Global South, more than two-thirds of people with high blood pressure go untreated. Only 30% of diagnosed patients receive treatment, and fewer than one-tenth have successfully controlled their disease.
Researchers found that initiating stroke treatment just 15 minutes faster can save lives and prevent disability. Busier hospitals, which treat more than 450 people for stroke each year, have better outcomes than those that treat fewer patients per year.
Researchers found that stress on immune cells and altered metabolism lead to different outcomes in individuals infected with the same virus, with potential targets for new treatments identified. Preventing conditions causing increased stress may also prevent disease from viral infections.
A new therapeutic target for the treatment of Alzheimer's disease has been discovered, with research identifying elevated levels of the protein SFRP1 in the brains and cerebrospinal fluid of patients. Inactivated SFRP1 function prevents disease progression in mouse models.
A new international consensus document provides guidelines for the conduct of magnetic resonance imaging studies after a myocardial infarction. The main outcome measure recommended is absolute infarct size, with scanning timing between 3 and 7 days post-infarction.
Researchers develop a new method to detect rheumatoid arthritis by analyzing hand blood content using infrared spectroscopy. The technique can provide an early diagnosis and assess treatment effectiveness, potentially leading to better long-term outcomes for patients.
Researchers developed a stable cobalt(III)-nitrosyl complex, enabling controlled nitric oxide delivery to cells. This discovery has the potential to greatly impact treatment development for cardiovascular diseases, including vasodilation and enhanced neuroplasticity.
A significant decrease in depression cases was observed after CPAP treatment for sleep apnea in patients with cardiovascular disease. The study found that CPAP treatment had a broader benefit of preventing depression, independent of improved sleepiness.
A Michigan Medicine study found that white women and those with higher education levels are more likely to seek fertility treatment than other groups. Nearly 12.5% of women reported experiencing infertility, but only 33% of those with lower education levels sought care.
A new study proposes a novel, non-invasive test for assessing gut function that may help screen and monitor treatment of gut diseases. The test measures the concentration of gut bacterial products in patient's blood and stool, detecting gut leakage and its potential impact on IBD and other intestinal diseases.
A two-year social marketing campaign in California significantly encouraged more people to seek care for symptoms of mental distress. Exposure to the campaign increased recognition of mental illness and advocacy for those affected.
Researchers found that probiotic bacteria Pseudomonas fluorescens reduces the impact of white-nose syndrome in bat populations about five-fold. The treatment lengthened the amount of time bats stayed in the mine, allowing them to recover from the disease and emerge during spring-time when insects are available.
A new intelligent liver function test has been developed to detect liver disease decades before it can become fatal. The test has shown a 44% increase in diagnosis of liver disease, giving patients earlier access to treatment.
Research highlights patchy care, delayed diagnosis, and lack of guidance for treating first-time manic episodes. Effective treatments are available but often overlooked, exacerbating symptoms and worsening health outcomes.
The Obesity Society has developed two new resources to improve obesity medicine education in medical schools and advanced healthcare providers. The resources include the first set of competencies for caring for patients with obesity and a proposed standard of care for adults with obesity, aimed at enhancing patient care.
The International Association for Dental Research (IADR) and American Association for Dental Research (AADR) honored the legacy of Ricardo Teles in a symposium. The symposium reviewed current knowledge in clinical periodontology, identified gaps in research, and recognized his contributions to advancing the field.
Researchers created a synthetic lubricant that mimics the natural lubricin found in joints, providing a potential cure for osteoarthritis. The synthetic lubricant is being tested in canine clinical trials and holds promise for future human use.
A study in CMAJ provides new insights into the decision-making processes of critical care physicians and families in withdrawing life-sustaining treatments from critically ill patients with severe brain injury. Key findings include the influence of patient circumstances, family wishes, severity and location of the injury, past physicia...
Researchers have developed a human cerebral organoid system, or 'mini-brain,' to study sporadic Creutzfeldt-Jakob disease (CJD) and its subtypes. The model enables evaluation of potential therapeutics and provides insights into human prion disease progression.
A Phase IIa trial found that verinurad with febuxostat significantly reduced urinary albumin-to-creatinine ratio by 39% and serum urate levels by 57% after 12 weeks. The effect was sustained through week 24.
A recent study from the University of Adelaide found that having braces does not necessarily lead to increased happiness or psychosocial outcomes in later life. In fact, people who did not receive orthodontic treatment were significantly more optimistic than those who had braces treatment.
A lack of representation of people with disabilities in the biomedical workforce can lead to limited care improvements. Researchers like Bonnielin Swenor advocate for increased diversity and accommodations to create more inclusive environments.
A study found that brain activity related to auditory perception parallels heart rate, suggesting that stress-induced changes in heart rate may impair auditory perception. Researchers suggest that vagus nerve activation by electrical stimulation could improve auditory perception and treat attention and communication disorders.
A study found that four out of five people with Functional Neurological Disorder (FND) experience lasting physical difficulties, with 80% still having symptoms in their arms and legs 14 years later. Doctors are urged to provide realistic prognoses and encourage targeted treatment for patients.
Researchers track early stages of alpha-synuclein protein aggregation in Parkinson's disease, which can lead to significant delay in disease progression. The study's novel method using super-resolution microscopy and advanced analysis has the potential to detect disease progression before symptoms appear.
A new study published in Alimentary Pharmacology & Therapeutics found that gastric bypass surgery improves acid reflux symptoms in most patients shortly after surgery. However, symptoms often return within 2 years, especially in women and older individuals with other medical problems.
Researchers at the University of Saskatchewan found that low-frequency magnetic stimulation improved cognitive and motor function in rodents with concussions. The therapy also protected the brain from future degeneration and restored normal sleep patterns.
A study by Children's National Hospital found that only 54.1% of teenagers diagnosed with chlamydia or PID filled their prescribed antimicrobial treatments, highlighting barriers to treatment adherence for this high-risk population.
A global registry demonstrates FFR provides valuable additional information after angiography, resulting in treatment changes in over a third of patients. The study showed more patients were assigned to medical management and CABG post-FFR than post-angiography.