Research on opioids, addiction, and treatment. Covers traditional care practices, opioid treatment in pregnancy, illicit fentanyl, and treatment disparities.
A new study suggests that ingestion of afterbirth may modify specific opioid-receptor systems in the brain, facilitating the onset of maternal behavior. The research, led by UB professor Mark Kristal, aims to determine how endogenous opioid activation during pregnancy and delivery influences maternal behavior.
Researchers analyzed pharmacy and clinical databases to identify high-risk opioid prescribing patterns. Patients without cancer were more likely to receive higher doses due to factors like older age, HIV/AIDS, and co-prescription of benzodiazepines.
A University of Michigan team found that only half of pharmacies in non-white areas had a sufficient supply of opioid painkillers. Pharmacies in wealthier ZIP codes tended to have better supplies, while those in poorer areas were less likely to carry the drugs due to perceived threats of robbery and street value.
A Duke University Medical Center study found significant regional disparities in opioid use for back pain, with higher rates in the South and among lower-income and less-educated individuals. The study suggests that improving prescribing patterns is crucial for effective national policy.
Researchers found that individuals with a family history of alcoholism are more likely to prefer sweet tastes than those without. This preference precedes the development of alcoholism and may serve as a marker for genetic risk. The study suggests that a simple test to assess sweet preference could help identify individuals at risk ear...
A new study found that levorphanol's ability to reduce pain is comparable to tricyclic antidepressants and gabapentin, commonly used drugs for neuropathic pain treatment. High-dose treatment provided greater pain reduction without tolerance, but also led to more side effects and participant dropout.
Researchers have found that delta opioid peptide may help protect brain cells from the ravages of Parkinson's disease by inducing a state of suspended animation. The compound was shown to reduce brain damage and neurological deficits in animal models of stroke, suggesting potential benefits for patients.
The Mayo Clinic study highlights the effectiveness of opioids in relieving chronic lower back pain, despite controversy over misuse and potential drug dependence. The research emphasizes the need for careful patient selection and close monitoring to ensure safe treatment outcomes.
A study in Calicut, India found no instances of misuse or diversion of oral morphine over 2 years. The research shows that opioids can be dispensed safely for home use with proper controls in place, overcoming regulatory barriers.