Articles tagged with Hypotension
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A recent study published in JAMA found that taking aspirin or clonidine before and after surgery did not lower the risk of acute kidney injury. The study involved over 6,900 patients and showed that major bleeding with aspirin increased AKI risk, while low blood pressure with clonidine had a similar effect.
Spontaneous intracranial hypotension, a condition causing severe headaches, has been linked to bariatric surgery. A study found that gastric bypass and banding surgeries were associated with a small percentage of people developing the condition.
A study of over 600 patients with acute kidney injury after cardiac surgery found that fenoldopam did not decrease the need for dialysis or mortality rates. Instead, it was associated with a higher incidence of low blood pressure.
The POISE-2 trial found that clonidine increased rates of clinically concerning hypotension and non-fatal cardiac arrest in patients undergoing non-cardiac surgery. The study showed higher risks from clonidine without counterbalancing benefits, contradicting earlier findings that suggested it would improve outcomes.
A Johns Hopkins-led study found a possible link between orthostatic hypotension and atrial fibrillation, increasing the risk by 40% over two decades. The condition is often asymptomatic and can lead to stroke, heart failure, and dementia if left untreated.
A study published in JAMA found that coprescribing calcium-channel blockers with clarithromycin increases the risk of hospitalization with acute kidney injury and hypotension. The risk was highest among patients taking nifedipine, suggesting a need for quality improvement initiatives to mitigate this largely preventable drug-drug inter...
A study published in JAMA found that individual financial incentives significantly improved blood pressure control, with an 8.36% increase compared to no incentive group. The use of guideline-recommended medications showed no significant difference between intervention and control groups.
Patients with low baseline diastolic blood pressure (DBP) had more subcortical brain atrophy progression. Those with declining DBP levels over time showed less brain atrophy progression compared to those with rising BP levels.
Researchers found that spaceflight compromises the ability of arteries and veins to constrict, leading to orthostatic hypotension upon return to Earth. This condition affects up to half of astronauts on short-term missions and nearly all on long-term missions.
A study published by the American Heart Association found that orthostatic hypotension may be associated with a higher risk of developing heart failure, particularly in individuals aged 45-55. High blood pressure was also found to contribute to this association.
A study found that mixing macrolide antibiotics with calcium-channel blockers increases the risk of hypotension and hospitalization in older patients. Erythromycin and clarithromycin were linked to a significant increase in hospitalizations, while azithromycin appeared safe.
A new study in Clinical Gastroenterology and Hepatology found that propofol administration by a trained professional results in a low rate of sedation-related complications. The study identified risk factors for complications and highlights the importance of proper training and patient selection.
A study of 2,929 individuals aged 65+ found that hospitalization for acute or critical illness was associated with lower cognitive scores and higher dementia risk. Noncritical illness hospitalizations had a 40% higher risk of dementia compared to never-hospitalized participants.
The new definition of syncope, including an aetiological requirement of reduced cerebral blood flow, provides a clearer picture of who and how many are affected by this common condition. The Guidelines identify three common types of syncope with different causes and risk profiles.
New research suggests that rapid response teams in hospitals do not reduce cardiopulmonary arrests or deaths. Despite widespread implementation, hospital-wide code rates and mortality rates remained largely unchanged after rapid response team intervention.
Researchers found a strong association between high arterial pulse pressure and high-tension open-angle glaucoma. Individuals with high pulse pressure were more likely to develop the condition, possibly due to increased carotid arterial stiffness.
A study published in JAMA found that tilarginine, a medication believed to benefit cardiogenic shock patients after a heart attack, had no effect on mortality rates. The trial tested the drug's efficacy in 398 patients and showed no difference in 30-day death rates between those who received tilarginine and placebo.
Researchers found that four major parameters return to normal after one day, and all changes recover within three days. Blood pressure variability is a key predictor of competition time, with low frequency variability being the most significant factor.
Researchers examined treatment to maintain blood pressure in patients with orthostatic hypotension (OH) caused by a neurological disease. Pyridostigmine bromide, approved for other uses, showed promise in improving symptoms and reducing standing blood pressure. The medication was found to be beneficial with minimal side effects.
Researchers at Mayo Clinic found that pyridostigmine improved patients' standing blood pressure and reduced symptoms without elevating blood pressure while lying down. The study showed significant results in reducing the need for other medications, particularly in those over age 70 with common causes like diabetes and Parkinson's disease.
A new study from the Mayo Clinic found that pyridostigmine improves standing blood pressure without increasing blood pressure when lying down, offering a safe treatment option for patients with orthostatic hypotension. The study involved 29 patients who were satisfied with the drug's effects, with 17 taking it as their primary treatment.
A new study finds that forgiveness is associated with lower resting diastolic blood pressure, especially among low-income black individuals. The research, conducted on a diverse sample of community residents, suggests that forgiving oneself and others may help mitigate cardiovascular risk factors.
A new study found that walking at moderate pace for 40 minutes a day can restore elasticity of carotid artery in postmenopausal women by 48%. This benefit may explain the positive impact of regular aerobic exercise on cardiovascular health.
A recent study found a significant association between low systolic blood pressure levels (below 130) and cognitive impairment in older patients with heart failure. The researchers suggest that routine management of heart failure should include assessment of cognitive performance to detect early signs of cognitive dysfunction.
A study published in Journal of the American Medical Association found that fludrocortisone had little effect on symptoms of chronic fatigue syndrome. The researchers tested isolating fludrocortisone as a treatment and found no significant improvement compared to a placebo.
A new study published in JAMA found that steroid hormone drug fludrocortisone does not alleviate symptoms of chronic fatigue syndrome (CFS), particularly neurally mediated hypotension (NMH). Researchers recommend further testing of other drugs or drug combinations to benefit CFS patients with NMH.
Researchers identified enlarged pituitary glands in patients with intracranial hypotension syndrome, a condition characterized by headaches that worsen when sitting up. The condition can be diagnosed through low spinal cord fluid pressure readings and treated with conventional therapies such as bed rest, hydration, and corticosteroids.
Researchers will study blood samples from sepsis patients to confirm the link between free radicals and falling blood pressure. The goal is to understand why blood pressure continues to plummet despite using pharmacological agents that should increase and maintain vascular pressure.
A study in mice found that genetic background influences blood-pressure response to acute alcohol exposure, with some strains experiencing increased blood pressure and others not. The findings suggest a predisposition to greater increases in blood pressure with alcohol consumption, potentially leading to hypertension.
A new study reveals Parkinson's disease is associated with a loss of norepinephrine-producing nerve endings in the heart, improving understanding of the disorder's development and potential prevention. This finding also sheds light on orthostatic hypotension, a common complication characterized by dizziness and fainting.
Researchers have identified a new treatment approach that could reverse the dramatic blood pressure drop associated with septic shock by removing excess superoxide free radicals. The treatment, a MetaPhore SOD mimetic, restored norepinephrine's ability to constrict blood vessels and reversed hypotension in rat models of septic shock.
A new study from the National Heart, Lung, and Blood Institute finds that systolic blood pressure is more accurate than diastolic pressure in identifying patients with hypertension. The study suggests that future treatment guidelines may emphasize systolic pressure, which correctly classified nearly 96% of patients.
Case reports reveal four patients died or went into shock after switching from mibefradil to other calcium channel blockers, highlighting the dangerous interaction between the two drugs. The risk is attributed to mibefradil's long half-life and its ability to inhibit liver enzymes that metabolize other medications.