The Lancet neurology reviews research on migraine genetics, highlighting the challenges of identifying genes involved in the disorder. The article also examines the implications of private diagnostic testing without physician support, sparking debate about its role in advancing treatment options for neurological diseases.
SourceThe Lancet_DELETED·JournalThe Lancet Neurology·DateAug 14, 2002
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A study by the University of Michigan found that migraine headaches affect 18% of women and 6% of men, resulting in significant lost productivity costs for employers. Employers can reduce these costs by providing education, preventive services, and direct treatment within the workplace.
SourceUniversity of Michigan·JournalJournal of Occupational and Environmental Medicine·DateAug 8, 2002
Researchers have identified a mouse model to investigate triggers of episodic neurological disorders, including common migraine and periodic paralysis. Two drugs, nimodipine and MK801, have been found to prevent attacks in mice, providing a potential new approach to understanding and treating these conditions.
SourceNIH/National Institute of Neurological Disorders and Stroke·DateAug 5, 2002
Researchers at Ohio University found that a behavioral therapy program reduced migraine frequency and severity in teens by 80%, with no medication required. The study suggests an alternative approach to treating migraines in children and teens.
A study presented at the American Academy of Neurology's annual meeting found that cortical spreading depression, a brain event linked to migraines, affects specific genes. Researchers identified two peptides influencing blood vessel activity and pain control, which may be related to menstrual migraine attacks.
A recent study found that migraine prevalence in the US has remained stable over the past decade, with many sufferers relying on over-the-counter medications. The study suggests that millions of people could benefit from proper medical attention, which can lead to more effective treatment and improved quality of life.
SourceAmerican Academy of Neurology·JournalNeurology·DateMar 25, 2002
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Researchers have found that treating inflammation in the trochlea tendon can relieve headache pain associated with migraines. In a study of five women with trochleitis, steroid injections produced relief from ocular pain and associated migraine symptoms within 48 to 72 hours.
SourceAmerican Academy of Neurology·JournalNeurology·DateMar 11, 2002
Researchers discovered a link between inflamed tender areas above upper molar teeth and headaches. A new treatment involves chilling the area to reduce swelling, eliminating pressure on nerves. The anti-inflammatory gel was found to be more effective than existing medications in reducing headache burden and analgesic use.
SourceWestchester Head and Neck Pain Center·DateFeb 20, 2002
A meta-analysis of 53 controlled clinical trials involving over 24,000 patients found that 10mg rizatriptan, 80mg eletriptan, and 12.5mg almotriptan showed better efficacy and consistency compared to sumatriptan. The results suggest that physicians need a variety of triptans in their repertoire to best treat patients with migraine.
A study found that biofeedback-assisted relaxation training techniques significantly reduced headache frequency and severity in children with migraines. The treatment improved school attendance by 85% of parents' reports, demonstrating its potential as a complementary therapy for managing migraines in children.
SourceAmerican Academy of Neurology·JournalNeurology·DateJan 8, 2001
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Women are twice as likely to experience migraine without aura during the first two days of their menstrual cycle. The study also found a higher risk of migraine in the two days before menstruation begins and a lower risk around ovulation.
SourceAmerican Academy of Neurology·JournalNeurology·DateNov 27, 2000
Research measures health-related quality of life among 'typical' migraine sufferers, showing a strong link between migraine and depression. Forty-seven percent of migraine sufferers experience depression, compared to 17% without migraine.
SourceAmerican Academy of Neurology·JournalNeurology·DateSep 11, 2000
A new study suggests that biofeedback training can significantly reduce the number, intensity, and duration of migraines in children. The training helps children learn to control their brain's slow cortical potentials, reducing the likelihood of future migraines.
SourceCenter for Advancing Health·JournalApplied Psychophysiology and Biofeedback·DateMay 24, 2000
A study published in Annals of Neurology reveals that people with migraines experience extreme skin sensitivity, which may explain why current medications are ineffective. The researchers suggest treating migraines as soon as the pain starts and developing new treatments targeting spinal cord neurons.
SourceBeth Israel Deaconess Medical Center·JournalAnnals of Neurology·DateApr 26, 2000
A Mayo Clinic study found a significant increase in migraine headaches among women between 1980 and 1994, with the highest incidence among young women. The study suggests that stress-related factors, such as increased work demands and single-parent households, may contribute to this trend.
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Researchers from the University of Iowa have identified a feedback loop mechanism that could explain the prolonged nature of migraines. The discovery reveals that inflammatory agents released during a migraine stimulate certain neurons to increase calcitonin gene-related peptides (CGRP) secretion, leading to persistent pain.
Researchers at Johns Hopkins Medicine have found the source of migraine pain to be changes within the meninges, the protective tissue layers covering the brain. The study uses SPECT scans to link abnormalities in the meninges with the site of pain.
The INSERM Collective Expertise Report on Migraine emphasizes that paramedical examinations are unnecessary for diagnosis, recommending a simple interview and medical examination instead. Effective treatments exist, but patients often underestimate their benefits, and confusion between triggers and underlying causes persists. The repor...
SourceFrench National Institute for Health and Medical Research (INSERM)·DateDec 16, 1998
Researchers monitored 60 migraine patients using transcranial Doppler ultrasound before and after six months of treatment. The study found that two-thirds of patients reported clinical improvement, with changes in blood vessel velocity supporting the findings.
Researchers identified a chromosome 8 gene linked to human epilepsy and migraines, also affecting mice with similar traits. The study suggests a potential cure or prevention method for these diseases.
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