A nationwide study found that frovatriptan succinate prevented menstrually associated migraines (MAM) in as many as half the women evaluated. The drug significantly reduced MAM severity and duration, as well as patients' functional impairment and use of rescue medications.
Patients with recurring migraines recorded non-headache symptoms in an electronic diary for three months, revealing a consistent pattern of symptoms leading up to the headache. The study suggests that learning to recognize these symptoms can help patients prevent or minimize their migraines, providing a new treatment option.
A community study of 400 patients with various pain types found that Keppra was well-tolerated and provided significant pain relief. The medication was effective in treating a range of conditions, including migraine headaches, nerve pain, and diabetic pain.
According to Dr. Robert Kaniecki, a University of Pittsburgh neurologist, migraine headaches are often underdiagnosed, with over 50% of patients being mislabeled as having 'sinus headache' or 'tension headache'. This can lead to excessive prescriptions for antibiotics and decongestants, contributing to antibiotic resistance.
A 12-week study shows candesartan cilexetil significantly reduces headache days and sick leave in patients with migraines. The medication's benefits are associated with good tolerability, making it an exciting alternative to current therapies.
The American College of Physicians and the American Academy of Family Physicians have released new guidelines for treating migraines, recommending immediate treatment with NSAIDs or triptans, as well as managing nausea and vomiting symptoms. The guidelines also emphasize the importance of patient involvement in charting migraines and i...
The Lancet neurology reviews research on migraine genetics, highlighting the challenges of identifying genes involved in the disorder. The article also examines the implications of private diagnostic testing without physician support, sparking debate about its role in advancing treatment options for neurological diseases.
A study by the University of Michigan found that migraine headaches affect 18% of women and 6% of men, resulting in significant lost productivity costs for employers. Employers can reduce these costs by providing education, preventive services, and direct treatment within the workplace.
Researchers have identified a mouse model to investigate triggers of episodic neurological disorders, including common migraine and periodic paralysis. Two drugs, nimodipine and MK801, have been found to prevent attacks in mice, providing a potential new approach to understanding and treating these conditions.
Researchers at Ohio University found that a behavioral therapy program reduced migraine frequency and severity in teens by 80%, with no medication required. The study suggests an alternative approach to treating migraines in children and teens.
A study presented at the American Academy of Neurology's annual meeting found that cortical spreading depression, a brain event linked to migraines, affects specific genes. Researchers identified two peptides influencing blood vessel activity and pain control, which may be related to menstrual migraine attacks.
A recent study found that migraine prevalence in the US has remained stable over the past decade, with many sufferers relying on over-the-counter medications. The study suggests that millions of people could benefit from proper medical attention, which can lead to more effective treatment and improved quality of life.
Researchers have found that treating inflammation in the trochlea tendon can relieve headache pain associated with migraines. In a study of five women with trochleitis, steroid injections produced relief from ocular pain and associated migraine symptoms within 48 to 72 hours.
Researchers discovered a link between inflamed tender areas above upper molar teeth and headaches. A new treatment involves chilling the area to reduce swelling, eliminating pressure on nerves. The anti-inflammatory gel was found to be more effective than existing medications in reducing headache burden and analgesic use.
A meta-analysis of 53 controlled clinical trials involving over 24,000 patients found that 10mg rizatriptan, 80mg eletriptan, and 12.5mg almotriptan showed better efficacy and consistency compared to sumatriptan. The results suggest that physicians need a variety of triptans in their repertoire to best treat patients with migraine.
A study found that biofeedback-assisted relaxation training techniques significantly reduced headache frequency and severity in children with migraines. The treatment improved school attendance by 85% of parents' reports, demonstrating its potential as a complementary therapy for managing migraines in children.
Women are twice as likely to experience migraine without aura during the first two days of their menstrual cycle. The study also found a higher risk of migraine in the two days before menstruation begins and a lower risk around ovulation.
Research measures health-related quality of life among 'typical' migraine sufferers, showing a strong link between migraine and depression. Forty-seven percent of migraine sufferers experience depression, compared to 17% without migraine.
A new study suggests that biofeedback training can significantly reduce the number, intensity, and duration of migraines in children. The training helps children learn to control their brain's slow cortical potentials, reducing the likelihood of future migraines.
A study published in Annals of Neurology reveals that people with migraines experience extreme skin sensitivity, which may explain why current medications are ineffective. The researchers suggest treating migraines as soon as the pain starts and developing new treatments targeting spinal cord neurons.
A Mayo Clinic study found a significant increase in migraine headaches among women between 1980 and 1994, with the highest incidence among young women. The study suggests that stress-related factors, such as increased work demands and single-parent households, may contribute to this trend.
Researchers from the University of Iowa have identified a feedback loop mechanism that could explain the prolonged nature of migraines. The discovery reveals that inflammatory agents released during a migraine stimulate certain neurons to increase calcitonin gene-related peptides (CGRP) secretion, leading to persistent pain.
Researchers at Johns Hopkins Medicine have found the source of migraine pain to be changes within the meninges, the protective tissue layers covering the brain. The study uses SPECT scans to link abnormalities in the meninges with the site of pain.
The INSERM Collective Expertise Report on Migraine emphasizes that paramedical examinations are unnecessary for diagnosis, recommending a simple interview and medical examination instead. Effective treatments exist, but patients often underestimate their benefits, and confusion between triggers and underlying causes persists. The repor...
Researchers monitored 60 migraine patients using transcranial Doppler ultrasound before and after six months of treatment. The study found that two-thirds of patients reported clinical improvement, with changes in blood vessel velocity supporting the findings.
Researchers identified a chromosome 8 gene linked to human epilepsy and migraines, also affecting mice with similar traits. The study suggests a potential cure or prevention method for these diseases.