Articles tagged with Coma
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that comatose patients' brain networks are restructured in a radical way, with some regions becoming hubs and others less connected. This changes could be linked to consciousness disorders and may help clinical practitioners diagnose comatose patients more accurately.
A mathematical model predicts and explains the emergence of burst suppression, a low-activity state in response to reduced cellular energy. The study suggests that burst suppression may be used to guide induced coma and track recovery from brain injuries, offering new insights into brain neurochemistry and neurophysiology.
A review of general anesthesia, sleep, and coma reveals that a fully anesthetized brain is closer to the state of a coma patient than a person asleep. The study aims to improve diagnosis and treatment for sleep abnormalities and emergence from coma.
A review article brings together neuroscience and sleep medicine to understand the biological mechanisms underlying general anesthesia. The authors highlight differences between general anesthesia and states similar to sleep and coma, while also exploring how anesthetic agents interact with brain circuits.
Researchers at Northwestern University led by Theresa Pape are testing if familiar voices can facilitate brain repair and improve coma recovery. The study found that subjects responded more to family voices compared to non-familiar ones, with activated brain areas appearing on MRI scans.
A new tool helps neurologists identify comatose patients who are potential organ donors by analyzing four key factors: corneal reflex, cough reflex, motor response, and oxygenation index. This prediction can be made before a patient is taken off breathing support, benefiting both organ donation rates and medical resource allocation.
Scientists at the University of Wisconsin-Madison reported finding brain response patterns similar to those during natural deep sleep under anesthesia. The study suggests that loss of consciousness may be linked to a breakdown in cortical connectivity, lending support to the integrated information theory of consciousness.
Researchers found that patients with mild to moderate liver coma survived nearly 2.5 times more with N-acetylcysteine treatment than placebo, offering a new glimmer of hope for those affected by non-acetaminophen acute liver failure.
A Queen's University study found that locusts' brain disturbance during a coma-like state shares similarities with human migraines, strokes, and epilepsy. Researchers discovered that manipulating cellular signaling pathways in the brain could potentially modify the severity of these conditions.
A study published in The Lancet Neurology found that patients in a minimally conscious state may experience pain perception similar to healthy individuals. This suggests that these patients could benefit from painkilling treatment, which is currently challenging due to limited awareness of their condition.
Researchers at Queen's University have found a link between locusts' reaction to stress and human migraines. The study shows that the locust's coma-like state is similar to what happens in people during a migraine, suggesting an evolutionary connection.
Dexmedetomidine was found to reduce the risk of delirium and coma in ICU patients on respirators, with 4 more days alive without these conditions. Dexmedetomidine also provided sustained sedation and higher accuracy at meeting sedation goals without added cost of care.
Astronomers used Spitzer to study the Coma cluster, finding almost 30,000 objects, including 1,200 previously unknown dwarf galaxies. The discovery implies a total population of at least 4,000 dwarf galaxies in the cluster.
Researchers at San Francisco VA Medical Center found that administering glucose to treat hypoglycemia actually causes brain damage in rats, contrary to previous assumptions. Oxidative stress is triggered by the sudden return of glucose, leading to neuron death.
A Mayo Clinic study finds that newspaper articles tend to focus on young coma patients who are more likely to awaken and recover, creating a skewed public perception. The study also highlights the need for accurate representation of comas in media, noting that medical sources could provide more thorough information than police reports.
A new guideline developed by the American Academy of Neurology can predict the outcome for patients in a coma after CPR with great accuracy. The tests used to make these predictions include absent pupillary reflexes and corneal reflexes, as well as absent motor responses three days after cardiac arrest.
A Mayo Clinic study reveals that comas are often grossly misrepresented in movies, with inaccurate depictions of patients' appearances and care. The researchers propose solutions to improve accuracy in film portrayals, including collaborations between screenwriters and neurologists.
A study by Eelco Wijdicks and his son found that only two out of 30 movies with coma characters showed a reasonably accurate representation. Common inaccuracies include portraying comatose people as suddenly awakening with no physical or mental problems, or showing them with closed eyes only.
Researchers observed the impact of a copper projectile on Comet Tempel 1, finding it released approximately 4,500 tonnes of water vapor. The comet's surface was composed of icy grains that sublimed in sunlight, producing a bright tail. These findings suggest comets are more like 'icy dust balls' than previously thought 'dirty snowballs'.
The Mayo Clinic has developed a new coma measurement system called the FOUR Score, which quantifies the level of consciousness and severity of brain injury. The score, tested in 120 intensive care unit patients, provides more precise measurements and higher agreement between evaluators than the Glasgow Coma Scale.
Researchers at UCSF discovered that administering pyruvate along with glucose after a diabetic coma can prevent brain damage and subsequent memory and learning impairment. The therapy was shown to be more effective than treatment with glucose alone, with rats experiencing significant cognitive deficits when given only glucose.
A new evaluation tool, DOCS, reliably predicts recovery from coma by tracking neurobehavioral functioning changes. This allows for improved medical and rehabilitation management.
A two-part study examines the effectiveness of neurobehavioral function assessments during coma and stroke rehabilitation for elderly individuals. The Disorders of Consciousness Scale reliably predicts recovery of consciousness, while tracking individual neurobehavioral recovery patterns improves medical and rehabilitation management.
Researchers developed a new scale to predict recovery of consciousness from coma after brain injury. The Disorders of Consciousness Scale (DOCS) accurately detected improvements, declines, and plateaus in neurobehavioral functioning.
A study of 326 children with severe malaria found that 61% had retinopathy, which was associated with higher death rates and prolonged coma. The researchers suggest that retinal signs may be related to cerebral pathophysiology in childhood CM.
Researchers have found that PARP inhibitors can protect brain cells from damage caused by insulin shock, a common complication of severe hypoglycemia. The study shows significant reductions in brain cell death when rats received PARP inhibitors after being induced into a hypoglycemic coma.
University of Pennsylvania researchers have found that loss of consciousness is linked to specific angles of head rotation during car crashes. The study suggests that designing safer airbags and sports headgear could prevent or minimize coma in such incidents.