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Genetic paradox: Gene implicated in Alzheimer's disease appears to protect kidneys of heart surgery patients

A study by Duke University Medical Center researchers has found a possible genetic link determining which heart patients are more likely to suffer kidney damage after surgery. The research team found that the E-4 variant of the apolipoprotein APO gene, already implicated in Alzheimer's disease, appears to offer protection to the kidneys.

SourceDuke University Medical Center·JournalAnesthesiology·DateJul 26, 2000

Minimally invasive procedure offers long-term pain relief for patients with pancreatitis

A new minimally invasive procedure called endoscopic pancreatic sphincterotomy (EPS) has shown promise in providing long-term pain relief for patients with chronic pancreatitis. According to a recent study by Johns Hopkins physicians, 62% of patients reported significant improvement in their pain levels after undergoing the procedure.

SourceJohns Hopkins Medicine·JournalGastrointestinal Endoscopy·DateJul 24, 2000

Decision on when to operate for childhood ear infections depends on which surgeon you ask: Study

A study found that surgeons in Ontario have differing opinions on when to perform surgery on children with ear infections, citing varying factors. The researchers surveyed 17 clinical and social factors, but only six were agreed upon, highlighting the need for a revised approach to addressing this common Canadian procedure.

SourceUniversity of Toronto·JournalCanadian Medical Association Journal·DateApr 30, 2000

Bypass surgery dramatically more effective than angioplasty in protecting diabetics from heart attack death, find University of Pittsburgh researchers

Researchers found that bypass surgery significantly reduces mortality rates for diabetic patients undergoing revascularization procedures. The study, BARI, compared coronary artery bypass graft surgery with percutaneous transluminal coronary angioplasty in patients with multivessel coronary artery disease.

SourceUniversity of Pittsburgh Medical Center·JournalNew England Journal of Medicine·DateApr 4, 2000

Geography and physician caseload are key factors in oophorectomy rates, according to Yale study

A Yale study reveals that postmenopausal women's ovaries are often removed during hysterectomy due to geographical location and surgeon experience, sparking concerns about informed consent. The research highlights significant variation in oophorectomy rates across different areas of the state and among surgeons with varying caseloads.

SourceYale University·JournalObstetrics and Gynecology·DateNov 28, 1999

Who should have heart bypass surgery? New guidelines will help doctors, patients decide together

The new guidelines chart the rapid evolution of bypass surgery techniques and provide a framework for physicians to evaluate risks and benefits with their patients. The report categorizes heart patients into groups that predict how well bypass will work for them based on various factors.

SourceMichigan Medicine - University of Michigan·JournalJournal of the American College of Cardiology·DateSep 30, 1999

Laser heart treatment shown to be safe and effective at lowering pain associated with heart disease

Researchers found that transmyocardial laser revascularization (TMR) improves angina by at least 2 classes in 72% of patients, while also increasing myocardial perfusion by 20%. TMR safely and effectively improved heart function over a 12-month period, driving its use with difficult bypass and angioplasty procedures.

SourceRush University Medical Center·JournalNew England Journal of Medicine·DateSep 29, 1999

Family doctors too pessimistic about knee surgery risk

A University of Toronto study found the chance of needing a second operation following primary knee replacement surgery was between four and eight percent, half the rate expected by family doctors and rheumatologists. Younger patients with active lifestyles and those living in urban centers had slightly higher risks of follow-up surgery.

SourceUniversity of Toronto·JournalJournal of Bone and Joint Surgery·DateJun 28, 1999

Cardiac surgery patients at higher risk

A new study found that cardiac surgery patients with serum potassium levels below 3.5 mmol/L are twice as likely to experience arrhythmias and a doubled need for cardiopulmonary resuscitation. Investigators recommend screening and replenishing potassium on a case-by-case basis.

SourceUniversity of Michigan·JournalJAMA·DateJun 15, 1999

'Glitches' discovered and fixed in animal study make surgery for human pituitary tumors quicker, safer and less painful

Researchers at Cedars-Sinai Medical Center have developed a new endoscopic procedure to remove pituitary gland tumors, reducing trauma and complications. The technique has been refined after an initial animal study identified potential 'glitches' that were later addressed, resulting in improved outcomes for patients.

SourceCedars-Sinai Medical Center·JournalJournal of Laparoendoscopic & Advanced Surgical Techniques·DateJun 2, 1999

New Findings On Lung Transplantation And Esophageal Cancer: Incidence Of Chronic Rejection Less For Lung Recipients Who Receive Bone Marrow

Researchers at the University of Pittsburgh Medical Center found that simultaneous bone marrow infusions at lung transplantation significantly reduced obliterative bronchiolitis, a marker for chronic rejection. The study showed a 25% reduction in chronic rejection incidence among recipients who received bone marrow infusions.

Using Older Donors Can Increase Number Of Pancreas Transplants, Report University Of Pittsburgh Surgeons

A study by University of Pittsburgh surgeons found that organs from marginal donors can be just as effective as ideal donor organs in pancreas transplants. The researchers accepted organs from donors over 45 years old, resulting in a high graft survival rate and improved quality of life for patients with diabetes.

SourceUniversity of Pittsburgh Medical Center·JournalTransplantation·DateJan 27, 1999