Articles tagged with Drug Resistance
The international panel emphasizes that blood tests measuring HIV levels and CD4 cells should guide treatment decisions, rather than resistance testing. The panel also highlights the limitations of current resistance assays and recommends further epidemiological studies to monitor resistant strain prevalence.
Scientists have discovered that Helicobacter pylori resistance to metronidazole is caused by mutation in the rdxA gene. This gene codes for an enzyme that converts metronidazole into hydroxylamine, a mutagen and cancer-causing chemical.
Researchers found glioblastoma multiforme tumors resistant to procarbazine exhibited defects in mismatch repair, leading to drug resistance. The study may lead to more effective treatment of GBM, a common and virulent brain tumor.
Researchers at Johns Hopkins have found that spending more time and money on strict drug regimens saves money in the long run. The cost-effective strategy, called directly observed therapy (DOT), cures more people sooner and decreases the risk of developing TB germs resistant to treatment.