Articles tagged with Gene Repertoire
Researchers uncover pivotal role of ZmCCT2 in regulating maize mesocotyl length and adapting to high altitudes. Significant associations between genetic variations and mesocotyl lengths were found, highlighting the essential function of ZmCCT2 in promoting cell elongation.
Researchers explore various immunotherapies, including immune checkpoint inhibitors and adoptive cell therapies, as promising treatments for hepatocellular carcinoma. The review aims to overcome current limitations of targeted therapies by regulating the body's immune systems.
Researchers have developed a system to generate clonal sex cells in tomato plants, which they used to design the genomes of offspring. The resulting plants contain the complete genetic information of both parents, offering a potential solution to the labor-intensive and expensive process of producing hybrid seeds.
Researchers at La Jolla Institute for Immunology and Massachusetts General Hospital mapped the genome to understand how IKAROS controls healthy B cell development. They found that IKAROS solves a big problem in B cell development by bringing together far-away genes through looping, leading to proper expression and antibody production.
Researchers at the Babraham Institute have discovered that the 3D organisation of DNA in B cells allows for genes far away from each other to come together during antibody generation. This finding has implications for understanding why antibody diversity declines with age and suggests potential interventions.
Researchers at Children's Hospital of Philadelphia developed TEQUILA-seq, a cost-effective technology for targeted long-read RNA sequencing. This innovation enables accurate accounting of all RNA molecules emanating from a single gene, crucial for understanding diseases like cancer.
Researchers at Okayama University discovered genes and proteins responsible for the rapid contraction of axopodia in Heliozoa, a group of eukaryotes. The study identified key players in microtubule disruption, including katanin p60, kinesin, and calcium signaling proteins.
Researchers from OIST have sequenced the genome of pearl oysters, finding key differences between chromosome pairs that could impact immunity and pearl production. The study aims to identify resilient strains for aquaculture, addressing declining pearl production in Japan.
Corals have been found to possess a large and complex genetic repertoire, with estimates suggesting up to 25,000 genes. This discovery has significant implications for understanding the evolution of complex features such as the nervous and immune systems in vertebrates.
Researchers have identified a new family of genes that encode proteins functioning as bitter taste receptors, providing crucial insight into the organization of the taste system. The study reveals that these receptors are expressed in cells that also express gustducin, a coupling protein critical for sending bitter signals to the brain.
Victor Velculescu, a cancer researcher, develops SAGE technique to rapidly analyze gene expression in cells. The method provides a snapshot of all active genes and has potential applications in disease research.
Researchers have discovered a way to reprogram cells, enabling the selective expression of genes. This breakthrough could lead to new treatments for diseases by harnessing this technology to turn off or on specific genes in different cell types.
Researchers found a correlation between genetic variants and novelty-seeking and neuroticism genes in two-week-old babies. The study used the Brazelton Neonatal Behavioral Assessment Scale to assess behavioral responses to human and non-human stimuli, revealing early signs of potential psychiatric disorders.
Researchers at Columbia University have linked a particular odor to the proteins in the human nose that detect it for the first time. They matched the smell of meat to a specific protein in rat nerve cells, shedding light on how the sense of smell works.