PNNL researchers developed an ultrasonic tool to monitor key physical properties of fluid products in real-time. Additionally, the lab showcased a new mass spectrometry technique called DREAMS that analyzes more proteins with greater accuracy, providing insights into low-level proteins crucial for cellular processes.
A chemist at Ohio State University has won a national award for his work on studying reactive intermediates in chemical reactions. He is using high-tech techniques to 'freeze-frame' these ephemeral species, which are crucial in determining the success or failure of reactions.
Researchers developed a highly sensitive immunoblot method to detect PrPSc in vCJD tissues, revealing its presence in lymphoid tissues and high concentrations in tonsil. The findings suggest new models for risk-management and highlight the need for further investigation into peripheral tissue transmission.
Researchers at UT Southwestern Medical Center have identified a protein called myocardin, which is crucial for heart development in embryos. The study found that myocardin is necessary for the formation of cardiac genes and could potentially be used to convert non-cardiac cells into heart cells.
Researchers at Dendreon Corporation have developed a method for generating enhanced immune responses with potentially important implications for therapeutic cancer vaccines. The approach involves modifying antigens to optimize uptake and processing by dendritic cells, resulting in significant cytotoxic T-cell activity.
Researchers have developed a new technique to identify elusive human genes expressed at low levels, which could play crucial roles in normal processes or disease prevention. The approach reduces the 'tail' of genetic material, retaining more copies of these genes and increasing their discovery rate.
Researchers have developed a new method to find human genes by using analogous genes from other species, offering a more accurate approach than existing techniques. The method has been tested on nearly 100 genes, with 40 out of 47 mammalian reconstructions being perfect and 94-97% accurate in the remaining cases.