Articles tagged with Lysis
A two-step approach to gene expression creates more resilient producers of nanostructures for advanced sensing and therapeutics. This new genetic regulatory system ensures host cells remain healthy while producing functional nanostructures.
Researchers used advanced techniques to study phage infection at the level of individual bacterial cells. They found that coinfecting phages impede each other's entry, perturbing the cell's electrophysiology and affecting the outcome of infection. This discovery opens a new avenue for research in bacterial electrophysiology.
Researchers from Rice University discovered that viruses achieve precise timing in cell lysis by balancing the buildup and breakdown of holin proteins. This balance ensures optimal cell bursting, essential for viral replication, despite underlying randomness in biological processes.
Researchers at Osaka Metropolitan University developed a lysin from a bacteriophage that targets Staphylococcus hominis, a key contributor to body odor. The study's results could lead to a new treatment option for axillary odors, a common dermatological disorder.
A phase 2 trial PrE0405 showed an 85% complete response rate in 33 patients over 60 with mantle cell lymphoma who received venetoclax combined with bendamustine and rituximab. The combination was generally well-tolerated, with gastrointestinal toxicities common.
Phages weigh all options and make an informed decision whether to exit the dormant state and attack their bacterial host. The study found that some phage families have developed a complex decision-making strategy, receiving information from neighboring bacteria and controlling communication via arbitrium.
A protocol for detecting targeted chromosomal deletions induced by zinc finger nucleases allows researchers to estimate the frequency of ZFN-induced genomic deletions using PCR-based methods. Immunoprecipitation is also optimized with detailed instructions for lysis conditions, protease inhibitor cocktails, and general preparation.