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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

How cells correct errors under time pressure

A new mathematical theory explains how cells navigate the risk-speed tradeoff when dividing, balancing risk and speed to ensure survival. The theory applies broadly to all organisms, despite differences between yeast and mammalian cells.

Jellyfish's 'superpowers' gained through cellular mechanism

Researchers at Tohoku University have discovered the cellular mechanisms behind jellyfish's remarkable ability to regenerate body parts. The study found that free-swimming adult jellyfish possess actively proliferating cells controlling body-size, tentacle shape, and regeneration.

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Sony Alpha a7 IV (Body Only)

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The neural circuitry of parental behavior

Researchers have identified a network of brain cells that orchestrate parental behavior in mice, including hormonal changes and altered social behaviors. The discovery could one day help develop treatments for postpartum depression and other related conditions.

Some neurons choose mom's gene and others choose dad's

Research reveals that individual neurons or specific types of neurons can silence genes from one parent or the other, particularly during brain development. As the brain matures, these differences tend to decrease, but some genes continue to exhibit differential expression in adult brains.

Genomic imprinting gets complicated in adults

A recent study found that genomic imprinting, a process silencing one set of parental genes, can be regulated in adult tissues. The researchers observed variation in epigenetic marks between cell types, indicating a need for fine-tuned gene expression in different tissues throughout development and adulthood.

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MSU discovers a new kind of stem cell

Researchers at Michigan State University have discovered a new type of induced Xen (iXEN) stem cells that can be created by reprogramming mature adult cells. These cells have unique properties and can shed light on reproductive diseases, potentially leading to advances in regenerative medicine.

'Parent' cells reset the cell division clock

Researchers have discovered that cell division time is programmed by the 'parent' cell and varies between parent and offspring cells. The study's findings challenge a 40-year-old theory on cell division and provide a new model to predict how populations of cells divide.

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Protein changes are discovered that control whether a gene functions

A Penn State-led research team found that histone protein changes can control whether a gene functions, with the potential to maintain genetic expression and prevent disease. The study's findings have significant implications for the study of diseases like cancer and understanding cellular behavior.

Caltech team says sporulation may have given rise to the bacterial outer membrane

Researchers at Caltech used powerful imaging technique to study Acetonema longum, a bacterium with two membranes that responds to extreme situations by forming protective spores. The study found that the outer membrane may have originated from an inner membrane during sporulation, providing insights into its evolution and function.

New role found for a cardiac progenitor population

Researchers at the University of California - San Diego have found that parent cells involved in embryonic development can generate three important types of cells with potential for cardiac repair. The study suggests that restoring the ability of adult epicardial cells to generate cardiomyocytes may enhance their future potential for c...

Aging boosts chances that a family line will be long-lived

A new study suggests that aging has evolved as a strategy to allow family lines to persist longer. By concentrating cellular damage in one individual, the rest of the line can continue to reproduce without harm. This asymmetric reproduction method may be favored by evolution due to its potential to increase longevity.

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