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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Dartmouth study highlights brain cells' role in navigating environment

A Dartmouth study reveals that grid cells in the entorhinal cortex play a crucial role in generating the signal for spatial navigation. The findings contribute to our understanding of how we update our spatial perception as we move through our environment, which is essential for navigating and survival.

Many memories, many rooms

A study published in the Proceedings of the National Academy of Sciences found that rats can create a unique map for every environment, allowing them to remember distinct locations without mixing up similar events. This discovery sheds light on the brain's storage capacity and memory organization.

The brain's 'inner GPS' gets dismantled

Researchers at University of California, San Diego, have removed the brain area responsible for spatial navigation in rats, showing that other memory abilities remain intact. The study provides insights into Alzheimer's disease and stroke effects on the brain's navigational system.

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Activity in dendrites is critical in memory formation

Researchers at Northwestern University discovered that activity in dendrites is crucial for storing memories, contradicting current thought that cell body and dendrites serve the same function. The study used high-resolution microscopy to image individual neurons in a living animal navigating a virtual reality maze.

Neuroscientists: Brain activity may mark the beginning of memories

Researchers at Johns Hopkins University found that brain activity in place cells helps construct cognitive maps, a pattern of activity reflecting an animal's internal representation of its environment. This activation can mark the birth of a memory, as seen in rats who pause to inspect their surroundings and create new place fields.

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Schizophrenia linked to abnormal brain waves

Researchers at MIT have discovered a link between abnormal brain waves and schizophrenia symptoms in mice. The study found that mice lacking the brain protein calcineurin exhibit hyperactive brain-wave oscillations during rest and impaired mental replay, mirroring some schizophrenia symptoms.

Neural activity in bats measured in-flight

Scientists track Egyptian fruit bat flights using miniature wireless devices and find that place cells respond to spherical volumes of space, suggesting uniform perception of all three dimensions. The study provides new insights into navigation, spatial memory, and spatial perception.

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Going places: Rat brain 'GPS' maps routes to rewards

Researchers at Johns Hopkins Medicine discovered that the rat's hippocampus uses remembered spatial information to imagine routes, guiding behavior. This finding has implications for understanding memory and imagination in people with Alzheimer's disease and age-related cognitive decline.

A 'light switch' in the brain illuminates neural networks

Scientists use a novel technique to identify which neurons communicate with place cells, revealing the brain's sense of location is created by multiple specialized cell types. The study provides new insights into how cells in the hippocampus process and integrate sensory information.

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'Time cells' bridge the gap in memories of event sequences

New research finds that hippocampal neurons encode every sequential moment in a series of events, bridging gaps between discontiguous events. The activity of these 'time cells' signals the timing of key events and can differentiate between different types of sequences.

Experience puts the personal stamp on a place in memory

Researchers found that rats' place cells behave like new environments when they don't explore, highlighting the importance of direct experience in creating stable episodic memories. This discovery translates to humans, where recalling past experiences relies on autobiographical memory and direct recollection of events.

Brain's map of space falls flat when it comes to altitude

Scientists studied brain cells in rats and found that only place cells were sensitive to height, with weak responsiveness. The brain's sense of space is more accurate in horizontal directions, suggesting a flat map of space for altitude.

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How past experiences inform future choices

Researchers at MIT's Picower Institute for Learning and Memory found that some neural sequences in mice' brains that fired during a novel experience had already occurred before the animal rested. This phenomenon, called preplay, helps encode related experiences occurring in the future.

Better understanding of mapmaking in the brain

Scientists have found 'grid cells' for the first time outside of the entorhinal cortex in the rat brain, expanding our knowledge of how the brain generates internal maps. These grid cells work together with other neural cells to create a series of maps that help with navigation and recognition of specific landmarks.

An innate sense of direction

The study reveals that rodent brains contain working navigational neurons from birth, with different cell types maturing over time. This finding suggests that the sense of direction may be innate, but experience also plays a role.

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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

The 'satellite navigation' in our brains

Researchers have discovered that our brains contain a built-in navigation system, much like satellite navigation, with in-built maps, grids and compasses. The hippocampus is the key area responsible for learning, memory and navigation, which becomes more refined and powerful in London taxi drivers over years of experience.

The emergence of a sense of orientation

Scientists from Berlin developed a theoretical model that shows how an orientation map develops in the brain, allowing for the emergence of place cells and head direction cells. The model analyzes realistic image data to extract information relevant to orientation, leading to the formation of cognitive maps.

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Video game used for study of human navigation

A team of researchers used a computer game to study human navigation, identifying distinct brain cells responsible for spatial mapping (place cells) and goal-directed behavior (goal cells). The study demonstrates that humans use both visual and cognitive processes to navigate their environment.