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Dartmouth study highlights brain cells' role in navigating environment

A Dartmouth study reveals that grid cells in the entorhinal cortex play a crucial role in generating the signal for spatial navigation. The findings contribute to our understanding of how we update our spatial perception as we move through our environment, which is essential for navigating and survival.

Many memories, many rooms

A study published in the Proceedings of the National Academy of Sciences found that rats can create a unique map for every environment, allowing them to remember distinct locations without mixing up similar events. This discovery sheds light on the brain's storage capacity and memory organization.

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The brain's 'inner GPS' gets dismantled

Researchers at University of California, San Diego, have removed the brain area responsible for spatial navigation in rats, showing that other memory abilities remain intact. The study provides insights into Alzheimer's disease and stroke effects on the brain's navigational system.

Activity in dendrites is critical in memory formation

Researchers at Northwestern University discovered that activity in dendrites is crucial for storing memories, contradicting current thought that cell body and dendrites serve the same function. The study used high-resolution microscopy to image individual neurons in a living animal navigating a virtual reality maze.

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Neuroscientists: Brain activity may mark the beginning of memories

Researchers at Johns Hopkins University found that brain activity in place cells helps construct cognitive maps, a pattern of activity reflecting an animal's internal representation of its environment. This activation can mark the birth of a memory, as seen in rats who pause to inspect their surroundings and create new place fields.

Schizophrenia linked to abnormal brain waves

Researchers at MIT have discovered a link between abnormal brain waves and schizophrenia symptoms in mice. The study found that mice lacking the brain protein calcineurin exhibit hyperactive brain-wave oscillations during rest and impaired mental replay, mirroring some schizophrenia symptoms.

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Neural activity in bats measured in-flight

Scientists track Egyptian fruit bat flights using miniature wireless devices and find that place cells respond to spherical volumes of space, suggesting uniform perception of all three dimensions. The study provides new insights into navigation, spatial memory, and spatial perception.

Going places: Rat brain 'GPS' maps routes to rewards

Researchers at Johns Hopkins Medicine discovered that the rat's hippocampus uses remembered spatial information to imagine routes, guiding behavior. This finding has implications for understanding memory and imagination in people with Alzheimer's disease and age-related cognitive decline.

A 'light switch' in the brain illuminates neural networks

Scientists use a novel technique to identify which neurons communicate with place cells, revealing the brain's sense of location is created by multiple specialized cell types. The study provides new insights into how cells in the hippocampus process and integrate sensory information.

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'Time cells' bridge the gap in memories of event sequences

New research finds that hippocampal neurons encode every sequential moment in a series of events, bridging gaps between discontiguous events. The activity of these 'time cells' signals the timing of key events and can differentiate between different types of sequences.

Experience puts the personal stamp on a place in memory

Researchers found that rats' place cells behave like new environments when they don't explore, highlighting the importance of direct experience in creating stable episodic memories. This discovery translates to humans, where recalling past experiences relies on autobiographical memory and direct recollection of events.

Brain's map of space falls flat when it comes to altitude

Scientists studied brain cells in rats and found that only place cells were sensitive to height, with weak responsiveness. The brain's sense of space is more accurate in horizontal directions, suggesting a flat map of space for altitude.

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How past experiences inform future choices

Researchers at MIT's Picower Institute for Learning and Memory found that some neural sequences in mice' brains that fired during a novel experience had already occurred before the animal rested. This phenomenon, called preplay, helps encode related experiences occurring in the future.

Better understanding of mapmaking in the brain

Scientists have found 'grid cells' for the first time outside of the entorhinal cortex in the rat brain, expanding our knowledge of how the brain generates internal maps. These grid cells work together with other neural cells to create a series of maps that help with navigation and recognition of specific landmarks.

An innate sense of direction

The study reveals that rodent brains contain working navigational neurons from birth, with different cell types maturing over time. This finding suggests that the sense of direction may be innate, but experience also plays a role.

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The 'satellite navigation' in our brains

Researchers have discovered that our brains contain a built-in navigation system, much like satellite navigation, with in-built maps, grids and compasses. The hippocampus is the key area responsible for learning, memory and navigation, which becomes more refined and powerful in London taxi drivers over years of experience.

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The emergence of a sense of orientation

Scientists from Berlin developed a theoretical model that shows how an orientation map develops in the brain, allowing for the emergence of place cells and head direction cells. The model analyzes realistic image data to extract information relevant to orientation, leading to the formation of cognitive maps.

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Video game used for study of human navigation

A team of researchers used a computer game to study human navigation, identifying distinct brain cells responsible for spatial mapping (place cells) and goal-directed behavior (goal cells). The study demonstrates that humans use both visual and cognitive processes to navigate their environment.