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Human Bone Disorder Reproduced In Mice

Researchers have successfully replicated human bone disorder McCune-Albright syndrome in mice using a novel animal model. The model utilizes a combination of normal and mutant stromal cells, which are mixed together before transplantation into immune-compromised mice.

SourceNIH/National Institute of Dental and Craniofacial Research·JournalJournal of Clinical Investigation·DateApr 15, 1998
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Anti-Clotting Drug May Cause Potentially Fatal Platelet Disorder

Researchers found TTP develops within four weeks of starting ticlopidine therapy, causing mass destruction of blood platelets and high mortality rates. Early detection and treatment with plasmapheresis significantly reduce death risk, but most neurologists and cardiologists are unaware of this side effect.

SourceNorthwestern University·JournalAnnals of Internal Medicine·DateApr 1, 1998

Device For Detecting Osteoporosis Receives FDA Approval

A new device approved by the US FDA uses ultrasound technology to estimate bone density of the heel, identifying women at risk of developing osteoporosis. The Sahara Clinical Bone Sonometer can be used in offices and could increase access to testing, especially in rural areas.

SourceMassachusetts Institute of Technology·DateMar 30, 1998

Link Made Between Human Growth Hormone, Bone Quality In Mice

Human growth hormone increases bone size in mice but compromises bone quality, leading to increased brittleness and fracture risk with age. This study highlights the need for caution when prescribing human growth hormone, especially in individuals without specific medical needs.

SourceUniversity of Michigan·JournalJournal of Bone and Mineral Research·DateMar 30, 1998
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Mimicking The Thymus - A Tool In The Battle Against HIV

Researchers have developed a system to mimic the thymus in laboratory settings, enabling the study of HIV's effect on T-cell development. The model has shown that even immature T cells are susceptible to HIV infection, highlighting the need for treatment targeting young individuals.

SourceBritish Society For Immunology·DateDec 3, 1997

Gene Discovery Could Overcome Aluminum Barrier To Higher Wheat Yields Worldwide

Scientists have discovered a gene in rye that enables wheat to resist toxins in aluminum often found in acid soils. This breakthrough has the potential to increase wheat yields worldwide, particularly in regions where millions of acres are currently unsuitable for cultivation due to acidic soil conditions.

SourceUnited States Department of Agriculture, Agricultural Research Service·DateOct 15, 1996
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Imaging Methods Results In Better Care For Hand Problems

A new study published in The Journal of Plastic and Reconstructive Surgery found that non-invasive magnetic resonance angiography (MRA) and magnetic resonance imaging (MRI) can effectively manage vascular malformations. The imaging techniques showed the growths' connections to surrounding tissues, allowing for better treatment planning.

SourceJohns Hopkins Medicine·DateJan 2, 1996