Articles tagged with Regeneration
A recent study found that valproic acid significantly increased Bcl-2 and growth associated protein 43 expression, and reduced c-Jun expression after brachial plexus avulsion in Wistar rats. This suggests that valproic acid can protect neurons and enhance neuronal regeneration following the injury.
A recent study found that ursolic acid induces neural regeneration and repair after sciatic nerve injury in mouse models. The compound promoted the regeneration of injured nerve myelin sheaths and reconstructed muscular functions.
Researchers found that poly(lactic-co-glycolic acid) conduit transplantation can significantly enhance the quality of sciatic nerve regeneration compared to traditional autogenous nerve grafting methods. The conduits increased maximum tensile load, stress, and elastic limit load while reducing strain.
In a study published in Neural Regeneration Research, decimeter wave therapy was found to contribute to the regeneration and recovery of compressed nerves. Intraoperative electric stimulation also showed positive effects on nerve repair.
Researchers found that HEXIM1 blocks gene expression necessary for muscle regeneration after injury, leading to increased muscle mass and function in mice with reduced HEXIM1 levels. This suggests that HEXIM1 may be a key regulator of skeletal muscle regeneration and a potential therapeutic target for degenerative muscle diseases.
Researchers at Johns Hopkins Medicine have identified a protein called semaphorin 5A that prevents nerve growth after injury. By blocking its interaction with CSPGs, nerves can be freed to continue growing.
Acorda Therapeutics has received the L.W. Freeman Award for its pioneering work in regenerative therapies and functional improvements for spinal cord injury patients. The company's lead product, Fampridine-SR, is in Phase 3 clinical trials for chronic SCI and aims to restore function in people with SCI.
Damage to nerves caused by injury can lead to slow and poor recovery. However, a new study suggests that electrical stimulation can enhance nerve regeneration, allowing for faster healing in just two to three weeks. Researchers hope to test this method on people with nerve damage.
Researchers studying sea lamprey nerve regeneration found that fibers grow in the correct direction and create synapses with target cells, restoring function. The discovery led to hypotheses about a new mechanism of neurofilament transport pushing forward growth cones.