Articles tagged with Epigenetics
Researchers demonstrate that a combination of epigenetic drugs can reactivate the expression of over 1,000 genes in primary tumours of breast cancer patients. These reactivated genes play crucial roles in cell proliferation, differentiation, and immune recognition, suggesting increased anti-tumour effects.
Research suggests that embryonic nutrition can impact health outcomes, with adaptations set in place during fetal development potentially leading to benefits later in life. For example, meadow voles have coats thickened or thinned based on day length exposure in early pregnancy, with no immediate survival value but later benefits.
St. Jude researchers successfully cloned embryos from mouse medulloblastoma cells using a reprogrammed nucleus model, demonstrating the potential for epigenetic factors to cause tumors. The study provides valuable insights into the molecular basis of cancer and may lead to new therapies.
Researchers have found a possible association between IVF and an increased risk of Beckwith-Wiedemann syndrome (BWS), a genetic disorder that can predispose children to cancer. BWS is characterized by excessive growth and occurs in about 1 in 15,000 births, with the incidence being significantly higher among IVF-conceived babies.