Articles tagged with Genomic Regions
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers successfully reconstructed parts of the genome of a common mammalian ancestor using computerized paleogenomics, achieving an accuracy rate of 98%. This achievement provides a valuable window into the evolution of DNA in placental mammals.
Researchers found that the fungal genome's sex-determining region shares similarities with the human Y chromosome, including cluster formation of functionally related genes. This discovery may provide insight into infertility in fungi and humans, as well as disease mechanisms in C. neoformans.
A team of scientists identified genomic regions in wild tomato species that boost yield and drought resistance, outperforming commercially available hybrids. Their approach harnesses natural biodiversity to enrich the genetic basis of cultivated plants.
Researchers discovered 481 ultra-conserved elements in the human genome, which are long and evolutionarily frozen. These elements are associated with genes, particularly those involved in regulating gene expression through alternative splicing.
Researchers identified a single gene, glutathione S-transferase omega-1 (GSTO1), as a key factor influencing the age of onset for both Alzheimer's and Parkinson's diseases. The study used genomic convergence to narrow down the genome region associated with age at onset, providing potential new targets for treatment.
Stanford Medicine has been awarded a significant grant from the National Human Genome Research Institute. The funding will support research teams in analyzing small portions of the human genome using various techniques.
Bioinformaticians at UCSD have identified 400 'fault zones' in the human genome where gene rearrangements are more likely to occur, potentially leading to life-threatening genetic alterations. These findings challenge the long-held random breakage theory of evolution and may provide new insights into breast cancer and other diseases.
A team of 71 researchers compared the human genome to 12 vertebrates, including chimpanzees, mice, and rats, to identify conserved genetic regions. These regions are likely to control important functions such as gene expression and can provide clues about how each species evolved.
Scientists have identified 400 'fragile regions' in the human genome that are more susceptible to genetic rearrangements, which could lead to a better understanding of cancer and other diseases. The study's findings contradict previous theories on genomic breakage, suggesting that these regions are like fault lines in the genome.
Researchers mapped the 11q13 amplicon, a common genetic defect in oral and head and neck cancers. A new gene, TAOS1, was identified as overexpressed in cell lines with 11q13 amplification, suggesting its potential as a biomarker for diagnosis and prognosis.
Researchers found that gene swapping in mice leads to pro-B cell lymphomas, with amplifications of c-myc and IgH genes arising from chromosome translocations. The study uncovered a new mechanism for cancer formation involving the DNA-snipping enzyme RAG.
A team of scientists has successfully completed the sequencing of the Arabidopsis thaliana genome, paving the way for accelerated research in plant biology. The comprehensive analysis provides valuable insights into gene annotation, functional categories, chromosomal architecture, and transposable elements.
Researchers have sequenced a large segment of the mouse t-complex, identifying 11 nearly overlapping genes, six of which are previously undiscovered. These genes appear to be active in early embryonic development, suggesting that entire regions may turn on and off together as part of developmental choreography.
Researchers have located 67 gene regions in hypertensive rats that are also linked to high blood pressure in humans. This study uses a genome-wide approach to pinpoint the exact genes involved in human hypertension, accelerating the search for potential treatments.
Researchers have identified a genetic link between intersex goats and a rare human disorder causing excess eyelid growth and premature ovarian failure. The study found that the gene region responsible for intersex goats' hornlessness is similar to the human disorder Blepharophimosis Ptosis Epicanthus inversus syndrome.
The genomic sequence of the major histocompatibility complex (MHC) has been completed, providing a vital tool for improved diagnosis and treatment of diseases. This information will enable researchers to understand the origin of many common diseases and identify positions of genes on this important segment of the human genome.
A genome scan identified regions on chromosomes 2, 4, 10, 16, 17 and 18 that may contain genes influencing nicotine dependence. The study used two independent samples, with limited replication in several regions suggesting further investigation is warranted.
The 1996-1997 Human Genome Lecture Series featured nine speakers who discussed various aspects of the human genome, including genome sequencing, comparative genomics, and genetic research in specific populations. The series aimed to provide a comprehensive understanding of the human genome and its implications for genetics research.
A team of researchers from Oregon Health & Science University has identified three gene regions in mice that are linked to an increased risk of physical dependence on alcohol. The study's findings could lead to a better understanding of alcoholism and the development of new treatments.