Articles tagged with Multiple Genes
Scientists have identified a brain molecule called NEAT1 that appears to play a central role in triggering light sensitivity (photophobia) during migraines. By disrupting the normal balance of nerve signaling and pain regulation, NEAT1 makes nerves more sensitive to light.
The team developed a Synthetic Translational Coupling Element (SynTCE) that enhances the precision and integration density of genetic circuits in synthetic biology. This allows for more efficient gene circuit integration, minimizing interference between biological parts and enabling precise control over multiple genes.
Dr. Fyodor Urnav proposes a set of initiatives to address the crisis, including pooling patients by syndrome and permitting multiple gene editors in a single Investigational New Drug application. This approach aims to accelerate the development of CRISPR therapies for rare genetic diseases.
A new study has identified four genetic variants associated with the direction of human scalp hair whorls, revealing a polygenic inheritance pattern. The findings may help unravel biological processes related to abnormal neurological development.
Researchers, led by Elizabeth King, aim to develop a knowledge base on complex genetic traits using fruit fly models. The project seeks to address the scientific knowledge gap in this field by focusing on interconnectedness among multiple factors.
A new genome-editing strategy called DAP array can correct dozens of errors at the same time with high precision and efficiency, avoiding off-target edits. The technique leverages tRNA to drive multiple guide RNAs on a single array, then released individually by cells to direct genome editors for edits at multiple human genomic sites.
Researchers found that shishito peppers with fewer seeds exhibit a range of spiciness, from weak to strong. The genes involved in capsaicinoid synthesis showed a positive correlation with pungent intensity. By suppressing these gene expressions, breeders may develop varieties with consistent flavor and reduced spicy fluctuations.
A Yale research team designed a system to modify multiple genes in the genome simultaneously, reducing unintended effects. The gene-editing 'toolbox' provides a user-friendly solution for studying cancer and other diseases.
Researchers at Whitehead Institute developed a new gene regulation system called CRISPR-on, which can activate multiple genes concurrently and precisely control their expression levels. The system has been shown to be effective in both mouse and human cells as well as in mouse embryos.
Scientists at Whitehead Institute have developed a new method for creating genetically altered mice using the CRISPR/Cas technique, which can produce mice with multiple mutations in just three to four weeks. This breakthrough enables the study of human diseases in mice more efficiently and cost-effectively.
Researchers have identified multiple genes associated with systemic lupus erythematosus, a devastating autoimmune disease that affects 1-2 million Americans. The study found associations with ITGAM, KIAA1542, and PXK genes, as well as SNP rs10798269.