Articles tagged with Quantitative Trait Loci
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers generated a POLDIP2 knockout ARPE-19 cell line and found reduced mitochondrial superoxide levels, consistent with upregulated SOD2. The study demonstrates a potential role of POLDIP2 in regulating oxidative stress in AMD.
A new study published in The Crop Journal has identified the gl9 gene variant as a key factor in increasing grain size and reducing chalkiness in rice. By introducing this allele into elite rice varieties, scientists have improved grain length, width, and weight, leading to enhanced appearance quality and yield.
Researchers have identified a novel chromosomal section that confers resistance to both crown rust and powdery mildew diseases in oats. This breakthrough finding has the potential to improve oat yields and reduce disease susceptibility, benefiting human consumption and livestock production.
Scientists have identified the DOMINANT AWN INHIBITOR (DAI) gene in sorghum, which regulates the absence and shortening of awns. The gene encodes a protein that negatively regulates awn formation as a transcription factor, with implications for breeding modern awnless cultivars.
A recent study by La Jolla Institute for Immunology researchers has identified new subsets of CD4+ 'helper' T cells that are linked to autoimmune disease risk. The team used single-cell RNA sequencing to compare gene expression in over 1 million CD4+ T cells from 89 healthy donors, revealing sex-based differences in immune cell functio...
University of Illinois researchers found a key gene responsible for increasing soybean protein content by approximately 2%. The discovery could lead to significant increases in protein production, addressing global food security issues. However, the gene's function is unclear and may involve the plant's circadian machinery.
Plant geneticists have developed a new application of CRISPR technology to rapidly generate variants of crops that display improved traits. By mutating regulatory regions, the scientists can achieve subtle changes in yield traits, providing flexibility for improving crop yields. This method has the potential to break yield barriers and...
A multi-state project will establish a nationally coordinated consortium to increase wheat yields through genetic advancements and breeding programs. Wheat geneticist Dr. Shuyu Liu and breeders Dr. Amir Ibrahim and Dr. Jackie Rudd will contribute to the major effort to improve wheat yields dramatically over the next decade.
Scientists discover that a small genetic change controls the response to pheromones in moths, allowing males to find female mates of their own species. This finding sheds light on the evolution of sexual communication and speciation in moths.
Researchers found that numerous small changes in multiple gene regions impact flowering time, reproductive ability, and other complex traits in corn. The study also identified subtle genetic variations influencing reproductive success, paving the way for more accurate predictions and breeding strategies.
The Tomato Analyzer software provides accurate and objective measurements of fruit shape, aiding morphological research. The analysis is more efficient for large numbers of subjects and detects traits difficult to quantify manually.
Researchers found that a single gene, glypican-3, plays a significant role in regulating body size in mice. The gene is already known to be associated with a rare human growth disorder, and its expression level correlates with size variation in both humans and mice.
Researchers found that Dahl R rats exhibit efficient spatial navigation, while Dahl S rats display poor spatial navigation. Analysis of F1 male progeny implicated the X chromosome in the impairment observed in Dahl S rats.
Researchers found that Arabidopsis plants from different latitudes exhibit significant variations in their circadian clocks, suggesting an adaptation to optimize fitness. The study identified five chromosomal regions contributing to the clock mechanism, including multiple genes that work together to control different parts of the process.
Researchers have developed a new genetic screening method that narrows the pool of candidate genes from thousands to fewer than 100, potentially saving time and money. The technique uses a combination of quantitative trait locus mapping and microarray technology to identify genes with differential expression, which are more likely to b...
Researchers have identified the first genetic loci associated with aerobic capacity in rats, revealing a complex relationship between inherited traits and exercise. The study used a genome scan to find quantitative trait loci (QTLs) linked to aerobic running capacity and found significant associations on chromosomes RNO16 and RNO8.