Researchers at Duke University Medical Center discovered that the cytokine interleukin-17 plays a significant role in disc disease and may lead to the development of new therapeutic approaches. Targeting this immune response could reduce painful inflammation and halt the evolution of arthritis.
SourceDuke University Medical Center·JournalArthritis & Rheumatism·DateJun 29, 2010
Natural killer cells help maintain a balance between T cells and the immune system, preventing over-response that can cause harm. Understanding how to keep NK cells around could lead to new treatments for patients with compromised immune systems.
SourceBrown University·JournalJournal of Experimental Medicine·DateOct 1, 2009
A new mouse model reveals that innate immunity plays a key role in driving symptoms of auto-inflammatory diseases. The study shows that the innate immune system is responsible for the over-activation leading to inflammation and symptoms.
SourceUniversity of California - San Diego·DateJun 4, 2009
Scientists at Mayo Clinic and VBI aim to understand how environmental fungus Alternaria triggers airway inflammation and bronchial asthma. They plan to develop specific therapies and prevention strategies by studying the role of fungal enzymes in innate immune responses.
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers challenge traditional hypotheses on Crohn's disease, suggesting a more complex role for cytokines in the immune response. This could lead to new treatment strategies involving the blockade of multiple cytokines.
SourceUniversity of Virginia Health System·JournalNew England Journal of Medicine·DateNov 11, 2004
A new study suggests that using stents to open blocked blood vessels in branching passages can lead to a harmful blood flow pattern, resulting in rapid re-occlusion of the main branch. This contradicts previous findings that suggest stenting was more successful in non-bifurcated areas.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 1, 2004
GammaDelta T cells are activated by bacterial pathogens, recognizing and responding to peptidoglycan patterns. They release pro-inflammatory cytokines to coordinate an immune response, providing innate protection against bacterial infections.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateOct 31, 2001