Articles tagged with Type 2 Diabetes
A new study found that fat mass index is associated with a higher risk of cardiovascular events in people with type 2 diabetes. Researchers analyzed data from the ACCORD study and found that participants with higher fat mass were at increased risk, while lean body mass did not provide protection.
A study found that patients with poor health were more likely to continue taking insulin after age 75, despite guidelines recommending reduced treatment intensity. Discontinuing insulin may outweigh its benefits for older adults, especially those with multiple health conditions.
Hurricanes Katrina and Rita had a significant impact on the mortality rate of seniors with diabetes, even ten years later. Those who lived in affected areas experienced a 40% higher one-month mortality rate compared to unaffected counties.
A new study found that using ACE inhibitors to lower blood pressure is associated with a 24% reduced risk of developing type 2 diabetes. Natural genetic variations in ACE concentrations are also linked to lower T2D risk. The researchers used Mendelian randomization to infer the causal effects of ACE inhibition on T2D risk.
A randomized clinical trial of 6,000 patients with type 2 diabetes compared the cardiovascular outcomes of linagliptin and glimepiride. The results suggest that linagliptin may be associated with reduced cardiovascular risk.
Researchers at Uppsala University have identified a previously unknown protein, Sac2, that regulates insulin secretion from β-cells. Lowering Sac2 levels leads to reduced insulin secretion, highlighting the importance of fat composition on secretory granule function.
A new study found that early combination therapy using vildagliptin and metformin leads to better blood sugar control and reduced treatment failure rates compared to metformin alone. The study showed a significant reduction in the risk of losing blood sugar control over a 5-year period.
A new study reveals that poor diabetes control leads to significant excess hospital costs, with people with type 1 and type 2 diabetes experiencing five-fold to eight-fold higher costs for elective and emergency care. The NHS in England spends £3 billion annually on avoidable hospital treatment related to diabetes.
Babies born weighing under 3.6kg are more likely to develop type 2 diabetes by 50.0 years vs 51.3 years, with lower BMI and higher HDL cholesterol at diagnosis. Low birthweight affects risk of developing type 2 diabetes in the same way irrespective of BMI and HDL cholesterol.
Researchers identified early metabolic features that can predict susceptibility to type 2 diabetes in children, including low HDL cholesterol and chronic inflammation. These findings may help prevent young people from developing the disease.
A new study found that socioeconomic factors significantly impact mortality and hospital readmission rates for patients with type 2 diabetes, but not type 1 diabetes. Patients from areas of high deprivation were more likely to die within six months of discharge.
A UK study found that the proportion of younger adults diagnosed with type 2 diabetes has increased since the start of the century. Younger cases have a more aggressive metabolic profile, including higher BMI, blood glucose levels, and cholesterol levels. This trend is associated with a higher risk of cardiovascular disease and mortality.
A meta-analysis found that drinking light to moderate amounts of alcohol decreases triglyceride levels and insulin in people with T2DM. The study suggests that further research is needed to evaluate the effects of alcohol consumption on blood sugar management
A new study found that obesity increases the risk of type 2 diabetes by 5.8-fold, while genetic predisposition and unfavorable lifestyle factors contribute less to the risk, but still play a role in its development. Lifestyle interventions can help delay the onset of T2D among high-risk subjects.
Researchers found increased AGE levels in eyes of people with type 2 diabetes and prediabetes, indicating potential for early detection through lens autofluorescence measurement. A new biomicroscope can detect these levels without invasive procedures.
Recent studies indicate a potential decrease in the rate of new type 2 diabetes cases, although overall prevalence continues to rise. The decline is attributed to improved care and longer survival rates, suggesting that public health initiatives may be contributing to the trend.
A new study developed a machine-learning derived model that can predict future heart failure among patients with diabetes. The WATCH-DM risk score is based on 10 variables, including weight, age, and diabetes control, and identifies patients at high risk of heart failure.
A national survey of primary care physicians reveals significant knowledge gaps about prediabetes risk factors, diagnostic criteria, and management practices. The study highlights the need for improved healthcare education and reimbursement systems to prioritize preventive measures over treatment.
Researchers from Trinity College Dublin isolated a family of proteins linked to better control of blood sugar levels in type 2 diabetes patients. These IL-36 cytokines alter the intestinal microbiome, potentially mitigating insulin resistance and glucose build-up.
A new study in Diabetologia reveals that shorter individuals are at a higher risk of developing type 2 diabetes. The research found that for every 10cm increase in height, the risk of type 2 diabetes decreased by 41% in men and 33% in women, adjusted for age and other factors.
A new meta-analysis found that SGLT2 inhibitors can reduce the risk of dialysis, transplantation, or death due to kidney disease by about 30% and also reduce the risk of acute kidney injury. The results are encouraging for people with diabetic kidney disease, offering a new treatment option to halt disease progression.
A new study confirms that SGLT2 inhibitors can prevent loss of kidney function and kidney failure in people with type 2 diabetes, reducing the risk by about 30%. The findings provide further strong support for the key role of SGLT2 inhibition in kidney protection.
A healthy lifestyle is associated with a 75% lower risk of developing type 2 diabetes, compared to the least healthy lifestyle. In individuals with type 2 diabetes, a healthy lifestyle also reduces cardiovascular disease and death risk by 56% and 52%, respectively.
Research found college students with diabetes experience high levels of distress, leading to poorer self-care behaviors and lower quality of life. Universities can offer resources such as diabetes education and accommodations to support these students.
Researchers analyzed 83 randomized controlled trials involving 121,070 people with and without diabetes. They found that increasing long-chain omega-3 fats had little or no effect on likelihood of diabetes diagnosis or glucose metabolism. In contrast, higher doses of long-chain omega-3 may have negative effects on diabetes risk.
A new study at the University of Kentucky reveals that mitochondrial changes, rather than glucose, drive chronic inflammation in type 2 diabetes. This finding challenges the long-held assumption that glucose is the primary cause of inflammation in the disease.
A study by Saint Louis University found that clinically meaningful PTSD improvement is associated with a 49% lower risk of incident type 2 diabetes. The researchers also discovered that in patients with both PTSD and depression, improvement in both conditions may be necessary to reduce the risk for type 2 diabetes.
A Finnish study found that lifestyle guidance and mobile application usage can reduce waist circumference and improve dietary habits. The study used a digital screening tool to identify at-risk individuals, with promising preliminary results.
A new study confirms that women with type 2 diabetes are at greater risk for sleep disturbances during the menopause transition. The study found a significant association between diabetes and increased severity of sleep-related symptoms, particularly in Asian women.
A study found that a diet with reduced carbohydrate content, high protein content, and moderately increased fat content improves patients' ability to regulate their blood sugar levels. This diet also reduces liver fat content and has a beneficial effect on fat metabolism in type 2 diabetics.
Researchers at Massachusetts General Hospital found that dietary fat quality and genetic risk of diabetes work independently, and a diet high in polyunsaturated fats can reduce type 2 diabetes risk. The study's findings support the deployment of lifestyle or dietary interventions for all gradients of genetic risk.
Researchers at University of Utah Health identified a specific class of gut bacteria called Clostridia that prevents mice from becoming obese. Giving these microbes back to mice with an impaired immune system allows them to stay slim, suggesting a potential therapeutic approach for humans.
Research reveals that African American families' cultural acceptance of larger body size and optimistic bias can limit their perceived risk for Type 2 diabetes. The study found that open communication within families and with medical professionals is essential for effective management of the disease. Parents who openly discuss their di...
A recent meta-analysis found that people with the highest adherence to predominantly plant-based diets had a 23% lower risk of type 2 diabetes compared to those with weaker adherence. Healthy plant-based foods have been shown to improve insulin sensitivity and blood pressure, reducing weight gain and inflammation.
This systematic review and meta-analysis found a significant association between adherence to plant-based eating habits and reduced risk of type 2 diabetes. Higher consumption of fruits, vegetables, whole grains, legumes, and nuts was linked to lower diabetes risk in adults.
A new study finds that diabetes confers a greater excess risk of heart failure in women than men, with type 1 diabetes associated with a 47% higher risk. The study suggests several potential explanations for this difference, including sex differences in diabetes management and cardiovascular risk factors.
A global study of 12 million people found that diabetes significantly increases the risk of heart failure, with women at greater risk than men. Type 1 and type 2 diabetes both pose a stronger risk for women, highlighting the need for sex-specific research into diabetes and its impact on heart health.
A global study of 12 million people found diabetes increases the risk of heart failure, with a significant increase for women. Women with type 1 diabetes have a 47% greater excess risk of heart failure compared to men, highlighting the need for sex-specific research.
A UK study found that diabetes patients experiencing greater empathy from their PCPs had a lower risk of all-cause mortality over 10 years. Patients with higher scores on the consultation and relational empathy (CARE) questionnaire reported better clinical outcomes.
A recent study found that metformin use was associated with a significantly lower risk of dementia in African American patients with type 2 diabetes. The study included data from over 73,000 male veterans and showed modest to no association between metformin and lower risk for dementia in white patients.
Researchers found that mice eating a high-fat diet who fasted every other day had reduced pancreatic fat and lower blood sugar levels. This suggests that intermittent fasting may be a therapeutic approach to prevent type 2 diabetes by reducing fat accumulation in the pancreas.
A study in the Journal of Diabetes Investigation reveals that adults with type 2 diabetes are at a higher risk of dying from cancer compared to the general population. The research found that cancer accounted for 27.8% of deaths among those with type 2 diabetes, while heart disease was the leading cause in the general population.
A collaborative study by Connecticut researchers shows that food insecurity is linked to insulin resistance and the development of type 2 diabetes in Latinos. The study found that households with food-insecure individuals had higher levels of inflammation, stress hormones, and insulin resistance compared to those who were food secure.
Researchers at Ohio State University report a significant reversal of metabolic syndrome in over half of participants after just four weeks on a low-carb diet. Despite no weight loss, the low-carb diet improved triglyceride levels and cholesterol readings, and increased fat-burning efficiency.
A UK study published in Diabetologia found that obesity during pregnancy is associated with a 3.5 times increased risk of type 2 diabetes in the child, while being overweight increases this risk by 40%. The study suggests strategies to reduce obesity and overweight in women of reproductive age are urgently needed.
Researchers at Chalmers University of Technology found that fatty fish provide clear protection against type 2 diabetes, but only if they are free from environmental pollutants. The study used innovative methods to analyze data and identified biomarkers in blood samples to objectively measure fish consumption.
A large international clinical trial found that dulaglutide reduced cardiovascular events by 12% and kidney disease by 15% in people with Type 2 diabetes. The study, REWIND, followed over 9,900 participants for five years.
Two new trials show oral semaglutide is more effective than subcutaneous liraglutide in treating type 2 diabetes, with the latest trial showing it's also safe for patients with moderate renal impairment. Another trial found that insulin degludec plus liraglutide is a durable therapy option for type 2 diabetes.
A study of adults and youth with type 2 diabetes found that improvements in insulin release wane after treatment stops, highlighting the need for continued treatment. In contrast, youth experience more aggressive disease progression during and after treatment.
Research from Nutrition 2019 reveals that consuming more plant-based foods can lower the risk of type 2 diabetes by 60 percent. Additionally, studies found that vitamins B2 and B6 may also play a role in preventing the disease. Furthermore, changing the order of food consumption can help reduce blood sugar levels after eating.
Researchers used exosomes to detect microRNAs targeting carbohydrate metabolism in obese teens. The study found a link between altered adipocyte-derived exosomal microRNAs and progression from obese normoglycemia to hyperglycemia/diabetes.
A large NIH-funded study found that taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk. The study, which enrolled over 2,400 participants, found no significant difference between those who took 4,000 IU of vitamin D and those who took a placebo.
The American Heart Association and the Heart Failure Society of America issue a statement on managing both conditions, highlighting lifestyle modifications and multidisciplinary care teams. The guidelines emphasize the importance of coordinated treatment to improve patient outcomes.
A study from Joslin Diabetes Center found that removing senescent beta-cells can recover their function and improve glucose metabolism in mice with insulin resistance. The researchers hope to develop a potential treatment using senolytics, which target aging cells contributing to disease dysfunction.
A Rutgers-led study concludes that bariatric surgery is an effective treatment for adolescents with obesity, as long as they can maintain a healthy lifestyle afterward. The procedure has been shown to remit type 2 diabetes and other complications of obesity in teens.
Research found that three months of high-intensity interval training improved heart function in adults with type 2 diabetes without medication changes. High-intensity exercise reversed some changes in heart function that precede diabetic heart disease.
A large international consortium analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. The study identified four genes with rare variants that affect diabetes risk, providing potential targets for new medicines and guiding researchers to better understand the disease.
A study funded by the NIH found that early weight-loss surgery in youth can lead to remission of type 2 diabetes and high blood pressure, compared to waiting until later in life. Teens who underwent gastric bypass surgery showed significant improvements in blood glucose control and reduced medication use.
A large Chinese study found that type 2 diabetes is associated with an elevated risk of 11 types of cancer in men and 13 types of cancer in women. The study, which examined data from over 410,000 adults, revealed significant increases in cancer risk for both men and women with diabetes.
A study by the University of Exeter found that 38% of patients with type 1 diabetes over 30 were initially treated as type 2. Half of those misdiagnosed remained so 13 years later. Insulin treatment is crucial for type 1 diabetes diagnosis.