Research on type 2 diabetes and its management. Covers nerve pain, early onset, BMI trajectories, and treatment side effects.
A study found that the gut microbiome can predict changes in glucose regulation, particularly related to insulin levels and secretion. The study suggests that certain microbes may be useful for predicting disease progression and informs future research.
Research found that morning exercise was associated with higher risks of developing coronary heart disease in men, while midday exercise had lower cardiorespiratory fitness levels. The study suggests that timing of physical activity may play a role in cardiovascular health outcomes for individuals with type 2 diabetes.
A recent study published in the Journal of the American Heart Association found that obesity contributes to up to half of new Type 2 diabetes cases annually in the United States. The research suggests that reducing obesity could prevent or delay the onset of type 2 diabetes, with public health efforts supporting healthy lifestyles pote...
A large study found that older adults with moderately elevated blood sugar levels do not frequently develop full-blown diabetes. Instead, many improve their blood glucose levels or die from other causes, suggesting that the 'prediabetes' diagnosis is less useful in this age group.
A large-scale analysis found a disproportionately higher COVID-19 death risk in middle-aged people with type 2 diabetes. The study suggests that vaccine prioritization strategies across Europe should consider the relative risk of COVID-19 mortality in this population.
Patients with extreme blood sugar swings between doctor visits face higher risk of heart disease, study finds. Wide variations in blood sugar levels are associated with poor health outcomes and even death, researchers suggest.
Researchers used machine learning models to identify metabolites in walnuts associated with a reduced risk of type 2 diabetes and cardiovascular disease. The study found a 17% lower risk of type 2 diabetes and 29% lower risk of cardiovascular disease, contributing to our understanding of the health benefits of walnuts.
Research published in the American Heart Association's Circulation Journal found that women with a history of gestational diabetes during pregnancy have a two-fold higher risk of coronary artery calcification, a strong predictor of heart disease. Attaining healthy blood sugar levels after pregnancy does not decrease this risk.
A team of researchers found that immature beta-cells can contribute to proper insulin release when paired with more mature counterparts. By balancing the proportion of 'weak' and 'strong' beta-cells, islet function can be restored under conditions of metabolic stress.
A study of 44,541 women found that taking metformin to treat type 2 diabetes may protect against developing ER-positive breast cancer. However, the risk of triple negative breast cancer was increased by 74% among those treated with metformin. The link between type 2 diabetes and breast cancer varied by breast cancer subtype.
A new study published in The Lancet found that metabolic surgery is more effective than medications and lifestyle interventions in controlling severe type 2 diabetes. Over 37.5% of surgically-treated patients achieved diabetes remission for the entire 10-year study period.
A large observational study published in Diabetologia found that obesity is associated with a higher risk of microvascular complications in people with type 2 diabetes. The study suggests that maintaining a healthy body mass index (BMI) before and after a diabetes diagnosis can help prevent these complications. Furthermore, the researc...
Researchers are investigating whether changing mealtimes to earlier or later in the day can reduce the risk of developing Type 2 diabetes. The study, led by Dr Denise Robertson and Professor Jonathan Johnston, aims to explore the impact on participants' blood pressure, waist and hip circumferences, and food preferences.
A recent study found that patients taking metformin before COVID-19 diagnosis had a threefold decrease in mortality. The study also suggests that metformin's anti-inflammatory and anti-thrombotic effects may be responsible for this benefit.
A new study confirms that treatment with Bimagrumab is safe and effective for treating excess adiposity and metabolic disturbances in adult patients with obesity and type 2 diabetes. The medication achieved a nearly 21% decrease in body fat and a 6.5% reduction in body weight, along with a gain of lean mass.
A low-carb diet may lead to higher rates of type 2 diabetes remission in the short term, with benefits diminishing at 12 months. The study found that low-carb diets increased weight loss and reduced medication use, but also showed worsening quality of life and cholesterol levels at longer term.
Researchers have identified six distinct subtypes of prediabetes, differing in disease development and risk. These subtypes can be used to predict individual risk of developing diabetes and secondary diseases, enabling targeted prevention measures.
Researchers at Oregon State University found that specific beneficial microbes can improve glucose metabolism and reduce obesity risk in mice fed a western diet. The study identified four bacterial species with potential therapeutic applications for type 2 diabetes, opening new avenues for probiotic treatments.
Researchers found that intensive glycemic control reduced CAN risk in individuals with no history of cardiovascular disease by 17%, while intensive blood pressure control reduced risks by 22%. Intensive glucose treatment was more effective in individuals without a history of CVD, whereas blood pressure lowering was more effective in ol...
A study of 1.3 million people reveals that younger adults with type 2 diabetes diagnosis are associated with a higher risk of mortality and cardiovascular disease. Early interventions to improve blood glucose levels and cardiovascular risk profiles are essential to reduce ill health and mortality.
A recent study published in Surgery for Obesity and Related Diseases found that bariatric surgery significantly reduced the long-term risk of cardiovascular disease in teenagers with type 2 diabetes. The study compared two cohorts of adolescents with type 2 diabetes over a five-year period, with results showing that treatment with bari...
A large cohort study found that dog owners with diabetes are 38% more likely to develop type 2 diabetes than those without. In contrast, no shared risk was detected in cat owners and their cats.
A study published in The BMJ found that dog owners with diabetes are more likely to develop type 2 diabetes themselves than owners without a diabetic dog. However, no shared risk was found between cat owners and their pets.
Researchers found COVID-19 infected individuals with type 1 and type 2 diabetes are three times more likely to have severe illness or require hospitalization compared to those without diabetes. The study urges policymakers to prioritize these individuals for COVID-19 vaccination.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that gastric bypass surgery can lead to long-term diabetes remission in over half of adults with type 2 diabetes. The study suggests that weight loss is not the only factor contributing to improved blood sugar levels.
The USPSTF recommends offering behavioral counseling interventions to promote a healthy diet and physical activity among adults with cardiovascular disease risk factors. Adults who adhere to national guidelines have a lower risk of cardiovascular disease and death compared to those who do not.
India's metropolitan cities face a devastating diabetes crisis, with over half of men (55%) and two-thirds of women (65%) projected to develop type 2 diabetes in their lifetime. Obesity is a major factor, with obese individuals facing significantly reduced life expectancy without diabetes.
A study of over 25,000 female health professionals found that a Mediterranean-style diet was associated with a 30% lower risk of developing type 2 diabetes. The diet's impact on insulin resistance, body mass index, and inflammation were key factors in this reduced risk.
A European study confirms that altered intestinal microbiota increases the production of imidazole propionate, a molecule that prevents insulin's blood sugar-lowering effects. Elevated levels of imidazole propionate are also found in prediabetes, suggesting it may contribute to disease progression.
Research from the University of Eastern Finland explores the role of diabetes in cellular and molecular changes underlying Alzheimer's disease. Diabetes was found to weaken the accumulation of microglial cells around amyloid plaques and increase the formation of neuritic plaques with prominent tau pathology.
A novel diabetes medication, sotagliflozin, significantly reduces hospitalization for heart failure, heart attack, and stroke in patients with Type 2 diabetes and chronic kidney disease. The study found a 26% decrease in cardiovascular deaths and hospitalizations.
Finerenone reduced the risk of heart attack, stroke, heart failure, and other negative cardiovascular events in patients with chronic kidney disease and Type 2 diabetes. The medication also reduced the rate of death, hospitalization for heart failure, and worsening kidney disease among these patients.
The SCORED and SOLOIST trials demonstrate the benefits of SGLT2 inhibitors in patients with type 2 diabetes and chronic kidney disease or recent worsening heart failure. These trials show significant reductions in cardiovascular events, including deaths, hospitalizations, and strokes.
Researchers found that people with Type 2 diabetes still have a 21% higher risk for cardiovascular disease and 31% higher risk for heart failure hospitalization. Optimizing five key cardiovascular risk factors can help reduce this impact, according to the American Heart Association.
A new study published in JAMA Internal Medicine shows that providing support for small lifestyle changes can almost halve the risk of developing Type 2 diabetes. The Norfolk Diabetes Prevention Study found that modest weight loss and increased physical activity reduced the risk by 40-47% for those with prediabetes.
A new report from The Lancet Commission on Diabetes highlights the need for evidence-based interventions to close the gap in diabetes prevention and care. Implementing six key components can reduce cardiovascular-renal events by up to 40% and prevent premature deaths.
A University of Gothenburg study shows that a molecule from gut bacteria, imidazole propionate, reduces the efficacy of metformin in lowering blood glucose. The study found high levels of imidazole propionate associated with impaired metformin action in type 2 diabetes patients.
A study suggests that losing fat mass, but not lean mass, is key for heart health in obese patients with type 2 diabetes. Reducing body fat and waist circumference lowers the risk of heart failure in this population.
A new study published in The Journal of the American Osteopathic Association found that increased social support reduces diabetes-related distress and improves treatment outcomes. Researchers emphasize the importance of integrating patients' family and support systems into their diabetes management plans to optimize care.
A new study from the University of Eastern Finland shows that physical activity and dietary counselling significantly reduces insulin resistance in normal-weight children, preventing type 2 diabetes. The intervention also boosts metabolism in skeletal muscles, adipose tissue, and the liver.
Mice fed a Western diet showed faster decline in odor detection and learning abilities compared to controls. The researchers suggest high dietary sugar content, rather than obesity or hyperglycemia, may be linked to this deterioration.
Researchers found that weight-reduction surgery significantly reduces the risk of a second heart attack, cardiovascular event, and death among severely obese patients with a prior heart attack. Patients who underwent surgery also experienced improvements in sleep apnea, hypertension, cholesterol, and Type 2 diabetes.
A new study suggests that incorporating wrinkled 'super peas' into foods, such as whole pea seeds or flour, could help tackle the global type 2 diabetes epidemic by preventing 'sugar spikes'. The research found that consuming these peas resulted in a more stable increase in blood sugar levels compared to regular peas.
A study of 4923 Japanese individuals with type 2 diabetes found that drinking 4 or more cups of green tea daily and 2 or more cups of coffee daily was associated with a 63% lower risk of death. Higher quantities of both beverages were linked to even greater reductions in mortality risk.
A new study has shown that a minimally-invasive ablation procedure can rejuvenate the lining of the duodenum, leading to significant improvements in blood glucose control and weight loss. In a pilot study, 75% of patients with type 2 diabetes who underwent the procedure were able to discontinue insulin therapy within six months.
Researchers are collecting detailed health information from people with atypical forms of diabetes to understand their causes and differences from common types. The study aims to provide critical insight into the emerging spectrum of diabetes, potentially leading to new targets for prevention and treatment.
Exposing diabetic mice to electromagnetic fields normalizes two major hallmarks of type 2 diabetes, including reduced blood sugar levels and improved insulin sensitivity. The effects are long-lasting, suggesting a potential EMF therapy for managing diabetes during sleep.
A multicenter observational study found that sitagliptin improved survival rates in diabetic patients hospitalized with COVID-19 pneumonia. The study also showed reduced inflammation and improved clinical outcomes. A new randomized, placebo-controlled trial is now enrolling patients to confirm the findings.
A Canadian study of over 290,000 children found that those exposed to diabetes in the womb had a 50-200% higher risk of developing heart disease before age 35. The study also discovered that these children were more likely to develop high blood pressure and type 2 diabetes.
Two newer diabetes medications can significantly reduce the risk of heart disease, cardiovascular events, and end-stage kidney disease. They also lower blood pressure and slow chronic kidney disease progression.
A new study finds that regular use of acid reflux drugs is associated with a heightened risk of developing type 2 diabetes. The longer these drugs are taken, the greater the risk seems to be, prompting researchers to advise blood glucose check-ups for long-term users.
A recent clinical trial found that ertugliflozin demonstrated non-inferiority on the rate of cardiovascular death, heart attack or stroke compared to placebo. The study results add to growing evidence supporting guidelines for using SGLT2 inhibitors to prevent adverse cardiovascular outcomes in type 2 diabetes patients.
A large-scale US study found that housing instability is associated with poor blood sugar control in people with type 2 diabetes. The study of over 25,000 patients revealed that frequent address changes and housing insecurity are linked to higher risk of emergency department visits and lower vaccination rates.
A Canadian study found that SGLT2 inhibitors reduce the risk of cardiovascular events, including heart attack and stroke, among patients with type 2 diabetes. The study's findings suggest that these drugs offer cardioprotective benefits in a real-world setting.
Researchers found that patients taking HIV and hepatitis B treatment had a 33% lower risk of developing diabetes. The protective effect was replicated in multiple databases, suggesting that these drugs could be repurposed to prevent type 2 diabetes.
A six-year study found metformin slowed cognitive decline and reduced dementia risk in individuals with type 2 diabetes. Researchers believe the medication may also benefit those at risk of cognitive decline without diabetes. The study suggests a potential repurposing of metformin to prevent cognitive decline in older people.
A new study found that high-intensity interval training (HIIT) combining cycling and rowing improves insulin sensitivity and reduces blood sugar levels in individuals with obesity and type 2 diabetes. The study also showed improvements in body composition, including a reduction in fat mass and an increase in muscle mass.
Research shows that maintaining good cardiovascular health can significantly reduce the risk of developing type 2 diabetes in middle-aged individuals, regardless of their genetic susceptibility. The study found that individuals with ideal CVH had a lower lifetime risk of T2D compared to those with poor or intermediate CVH.
New research links diabetes to risk of COVID-19 infection and differential outcomes, highlighting the importance of optimising blood sugar control in people with type 1 and 2 diabetes. Better control appears to be an important modifier of COVID-19 severity, suggesting a therapeutic opportunity for diabetes management.
A nationwide study in Sweden found that non-Western immigrants experienced a higher risk of death with each generation born in the country. First-generation immigrants had a survival advantage compared to native Swedes, but this reduced over time and vanished in second-generation immigrants.