Articles tagged with Type 2 Diabetes
A study by the University of Exeter found that 38% of patients with type 1 diabetes over 30 were initially treated as type 2. Half of those misdiagnosed remained so 13 years later. Insulin treatment is crucial for type 1 diabetes diagnosis.
A clinical trial found liraglutide, an existing adult diabetes medication, effectively treats Type 2 diabetes in children. The study showed a significant reduction in A1C levels and improvements in glycated hemoglobin levels, offering new treatment options for this age group.
A new study from the University of Exeter Medical School found that using characteristics such as weight and age at diagnosis can help select the best diabetes drug for individuals. This approach is more effective than previous models, which divide adults with diabetes into subgroups.
Researchers discovered seven genetic variants linked to type 2 diabetes in young people, with one variant novel to youth. The study used data from a large pediatric cohort and found that obesity-related variants contribute to the risk of developing Type 2 diabetes in younger individuals.
A Johns Hopkins study found that few American adults eligible for diabetes prevention programs are being referred to or participating in these programs. Despite the high health and economic burden of type 2 diabetes, only 4.2 percent of those at risk were referred to a program, with even lower participation rates overall.
A randomized crossover trial found time-restricted eating improved glucose control, regardless of when the men chose to stop eating. The study's results suggest modulating meal times can improve glucose control and may lead to weight loss.
Research at Lund University explores how lifestyle affects gene activity in human tissues, including adipose tissue, skeletal muscle, pancreatic islets, liver, and blood. The study reveals the role of epigenetic changes in disease development and potential novel treatments.
Research highlights the association between chronic obstructive pulmonary disease (COPD) and type 2 diabetes, emphasizing the importance of collaborative care to address underlying systemic inflammation. Achieving optimal glucose control is crucial in patients with coexistent T2 DM and COPD.
A new study led by McGill University Health Centre researchers found that children born to mothers with gestational diabetes are nearly twice as likely to develop type 1 diabetes before the age of 22. Early detection is crucial in preventing complications like diabetic ketoacidosis.
Children born to mothers with gestational diabetes are nearly twice as likely to develop diabetes before age 22. Early detection is crucial, as many cases are diagnosed when symptoms like frequent urination and weight loss arise.
A landmark clinical trial shows that canagliflozin lowers the risk of kidney failure by 30% in people with Type 2 diabetes and kidney disease. The study also found a significant reduction in cardiovascular events, providing a promising new treatment option for patients at high risk.
Researchers found a link between prostate medicines and increased risk of type 2 diabetes in men taking 5-alpha-reductase inhibitors. Men on these medications should be monitored for warning signs of diabetes and have their prescriptions adjusted if necessary.
A UBC study found that a high-fat, low-carb breakfast can prevent large blood sugar spikes and improve glycemic control. Participants with well-controlled Type 2 Diabetes experienced reduced glucose exposure and improved stability of glucose readings after consuming a low-carb breakfast.
A new molecule, EPB-53, has been discovered to increase FGF21 levels in the liver and plasma through oral administration. This could lead to new therapeutic strategies for treating type 2 diabetes and non-alcoholic fatty liver disease.
Research found that people diagnosed with type 2 diabetes before age 40 have a significantly increased risk of death, stroke, heart attack, and other cardiovascular conditions. Women under 40 are at higher risk than men, while the risk decreases with increasing age of diagnosis.
A new UBC study found that consuming just one dose of carbohydrates while on a high-fat, low-carbohydrate diet can damage blood vessels. The researchers recruited nine healthy young males and had them consume a glucose drink before and after a seven-day keto diet, revealing biomarkers in the blood suggesting vessel wall damage.
Research suggests that spending large amounts of time sitting down increases the risk of cardiovascular disease, type 2 diabetes, and death. The study estimated that sedentary behaviour is associated with 11.6% of all deaths in the UK, with 69,276 potential deaths avoided if sedentary behaviour were eliminated.
A study found that community pharmacy-based type 2 diabetes screening is cost-effective and can increase early diagnoses by 3.3 years. Researchers suggest targeting high-risk patients to improve the service's cost-effectiveness.
A recent study found that moderate muscle mass reduces the risk of type 2 diabetes by 32 percent. The benefits were independent of cardiorespiratory fitness, and higher levels of muscle strength did not provide additional protection. Building strength with resistance exercise may be a helpful way to prevent type 2 diabetes.
A new study published in Diabetologia found that women who develop gestational diabetes (GDM) during pregnancy are at double the risk of cardiovascular disease (CVD) compared to those without GDM. The study also revealed that this increased risk remains even if women with GDM do not go on to develop type 2 diabetes.
Individuals taking statins may experience higher insulin levels and insulin resistance, leading to a greater risk of developing type 2 diabetes. The analysis found a 38% increased risk among those who used statins for 15 years or more.
Researchers have developed an app that uses a smartphone camera and photoplethysmography signal to detect diabetes, showing promise for early detection and encouraging further testing by healthcare providers. The app was tested on over 54,000 individuals and correctly identified people with diabetes in over 72% of cases.
A randomized controlled trial found that resistance training and aerobic training plus resistance training significantly reduced the incidence of type 2 diabetes. The study showed that these exercise programs can be as effective as isolated aerobic training in preventing overt type 2 diabetes.
A randomized clinical trial found that a behavioral intervention with counseling sessions improved sustained physical activity and reduced sedentary behavior in patients with type 2 diabetes. The study compared the intervention to standard care with general physician recommendations.
A plant-based meal has been shown to increase the postprandial secretion of insulin and incretin hormones, particularly GLP-1, in individuals with type 2 diabetes. This improvement in beta-cell function parameters suggests a potential solution for managing and treating the condition.
Research by University of Sydney researchers reveals a significant association between diabetes and low back pain and neck pain. The study found people with diabetes have a higher risk of experiencing these conditions, warranting further investigation into the link.
A new study suggests the Affordable Care Act's requirements on pre-existing conditions and age clauses had a significant impact on adults with diabetes. The percentage of people with private health insurance who had diabetes increased after the ACA provisions began, especially among those in their 50s.
A new study published in Circulation Research found that eating nuts, particularly tree nuts, can lower the risk of cardiovascular disease among people with type 2 diabetes. The research showed that even small amounts of nuts had a significant impact on heart health.
A Texas A&M-led study reveals that estrogen can decrease insulin resistance and glucose production, reducing Type 2 diabetes incidences. The study highlights the importance of estrogen receptor signaling and Foxo1-mediated gluconeogenesis in regulating glucose homeostasis.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
A large-scale study has identified 28 novel genomic regions linked to type 2 diabetes in the Japanese population, including variants not found in European populations. The findings may lead to targeted therapeutic measures for preventing or treating diabetes in this ethnic group.
Researchers have developed a new risk score that takes into account genetic information to identify babies at high risk of type 1 diabetes. The score is nearly twice as efficient as existing methods and also effective at predicting type 1 diabetes in adults, helping with early diagnosis and treatment.
Patients with type 1 diabetes and poor blood sugar control face a higher risk of fragility fracture compared to those with good glycemic control. Good blood sugar control is an important goal for patients with diabetes, and research shows that it may help reduce the risk of fractures in type 1 diabetes patients.
A promising compound TTP399 targets glucokinase protein implicated in type 2 diabetes, improving glycemic control and reducing liver fat. Phase 2 clinical trial of 190 participants shows no adverse effects, paving way for potential new treatment options.
A study found that couples interventions for individuals with type 2 diabetes can reduce partners' diabetes distress and increase marital satisfaction. The intervention also improved diastolic blood pressure, but had no significant impact on weight loss or diet and activity behaviors.
A new study published in Cell Metabolism suggests that energy balance - the calories consumed versus burned - may not determine the development of gestational diabetes. Women with obesity tend to develop gestational diabetes due to primary risk factors such as excess fat and insulin resistance, which can be evident early in pregnancy.
A new study found that eating one egg per day is associated with a blood metabolite profile linked to a lower risk of type 2 diabetes. Researchers identified several biochemical compounds in blood that predicted a higher risk of developing the disease, including tyrosine.
A Northwestern Medicine study found that sulfonylureas and basal insulin increase the risk of heart attack, stroke, and amputation in patients with Type 2 diabetes. The study suggests a paradigm shift in treatment, recommending newer diabetes medications with more favorable cardiovascular profiles.
A large-scale genomic analysis found a strong link between type 2 diabetes and erectile dysfunction, suggesting that living a healthier lifestyle may help reduce risk. The study identified a genetic predisposition to type 2 diabetes as a cause of erectile dysfunction.
A recent study on Australian diabetics aged under 50 reveals an alarming rise in end-stage kidney disease, underscoring the need for aggressive risk factor treatment. The research highlights the importance of early intervention to mitigate this trend and alleviate pressure on Australia's kidney dialysis services.
A study of French women found that those experiencing migraines had a lower risk of developing type 2 diabetes compared to those without migraines. The observational study included over 74,000 women and suggests potential underlying causes for the association between migraines and type 2 diabetes.
A new study published in Diabetologia found that type 2 diabetes is associated with a decline in verbal memory and fluency over 5 years in older adults. In contrast to previous research, the study did not find a direct link between brain atrophy and cognitive decline in people with T2D.
Researchers have discovered a new therapeutic avenue for treating type 2 diabetes by targeting the interaction between hormone-sensitive lipase (HSL) and a transcription factor responsible for fatty acid synthesis. Decreasing HSL expression leads to improved insulin sensitivity, which may help prevent or manage the disease.
A large Nordic study found liraglutide reduces the risk of myocardial infarction, stroke, or cardiovascular death among type 2 diabetes patients. The study also showed a lower risk of cardiovascular death and any cause of death with liraglutide treatment.
Research reveals an increased risk of ill health in people with evening preference, including erratic eating patterns and consumption of unhealthy foods. The study also found that glucose levels increase when night owls eat shortly before bed, negatively affecting metabolism.
The project aims to improve diabetes management for Latinos through telementoring sessions, empowering primary care providers with advanced training. La Clínica del Pueblo and George Washington University launched the first ECHO site in the region to address high diabetes prevalence and long waitlists.
A study of over 143,000 female nurses found that rotating night shift work and an unhealthy lifestyle significantly increase the risk of type 2 diabetes. The risk is higher than the sum of individual factors, suggesting an interaction between the two.
Researchers found that non-invasive skin autofluorescence measurement can predict future risk of type 2 diabetes, cardiovascular disease, and mortality. A single measurement was associated with a 3-fold increase in risk of type 2 diabetes or CVD.
A global study predicts a 20% increase in insulin use by 2030 due to rising type 2 diabetes cases. Without improved access, nearly half of the 79 million adults with type 2 diabetes will not receive insulin.
Researchers have created an oral formulation of semaglutide, a successful type 2 diabetes therapy, that can be more readily absorbed in the stomach. This development has the potential to improve treatment flexibility and patient adherence to T2D treatment programs, offering patients a less invasive route of administration.
Research suggests moderate coffee consumption may reduce type 2 diabetes risk by 25%, with potential mechanisms including antioxidant and anti-inflammatory effects. The Institute for Scientific Information on Coffee reports findings from a meta-analysis of 30 studies involving over 1.1 million participants.
A study led by St. Michael's Hospital researchers found that empagliflozin significantly reduces left ventricular mass index, a key indicator of heart disease. The medication has profound cardiovascular benefits, including improved cardiac structure and reduced mortality rates in people with Type 2 diabetes and heart disease.
Research reveals epigenetic changes in IGFBP2 gene influence type 2 diabetes risk. Higher IGFBP2 levels in blood lower diabetes risk.
A new study from the University of Eastern Finland found that poor aerobic fitness in children is associated with a higher risk of type 2 diabetes and cardiovascular disease. The study's findings suggest that traditional measures of aerobic fitness may overestimate its role in identifying children at increased risk.
Researchers identified 14 genetic variants associated with fat storage patterns and their impact on metabolic risk. These genetic factors tend to protect against diabetes, heart disease, and hypertension when stored under the skin, rather than in organs like the liver.
A new report suggests that addressing chronic diseases like diabetes could save tens of billions of dollars in healthcare costs annually. Proper nutrition therapy and exercise can effectively cause remission of Type 2 diabetes, with a one percent decrease in HbA1c levels resulting in significant savings.
Researchers found a link between colectomy and increased risk of developing type 2 diabetes. The study, analyzing data from over 46,000 patients, suggests the colon plays a crucial role in regulating blood sugar levels.
A plant-based diet has been shown to improve psychological wellbeing, reduce risk factors for type 2 diabetes, and slow nerve damage. Participants who followed a vegan diet lost nearly twice as much weight and had lower blood glucose levels compared to those on other diets.
Lifestyle interventions, medication, and surgery can effectively delay or prevent type 2 diabetes in the majority of patients, but limited access to these treatments is a major issue. Evidence-based interventions show that weight loss through lifestyle changes or metabolic surgery can reduce the risk of diabetes by up to 78%.
A new study published by the American Academy of Ophthalmology suggests that taking metformin, a common diabetes medication, can lower the risk of age-related macular degeneration. Researchers found that patients who took metformin had half as many cases of AMD compared to those who did not.