Articles tagged with Type 2 Diabetes
A new study found that eating one egg per day is associated with a blood metabolite profile linked to a lower risk of type 2 diabetes. Researchers identified several biochemical compounds in blood that predicted a higher risk of developing the disease, including tyrosine.
A Northwestern Medicine study found that sulfonylureas and basal insulin increase the risk of heart attack, stroke, and amputation in patients with Type 2 diabetes. The study suggests a paradigm shift in treatment, recommending newer diabetes medications with more favorable cardiovascular profiles.
A large-scale genomic analysis found a strong link between type 2 diabetes and erectile dysfunction, suggesting that living a healthier lifestyle may help reduce risk. The study identified a genetic predisposition to type 2 diabetes as a cause of erectile dysfunction.
A recent study on Australian diabetics aged under 50 reveals an alarming rise in end-stage kidney disease, underscoring the need for aggressive risk factor treatment. The research highlights the importance of early intervention to mitigate this trend and alleviate pressure on Australia's kidney dialysis services.
A study of French women found that those experiencing migraines had a lower risk of developing type 2 diabetes compared to those without migraines. The observational study included over 74,000 women and suggests potential underlying causes for the association between migraines and type 2 diabetes.
A new study published in Diabetologia found that type 2 diabetes is associated with a decline in verbal memory and fluency over 5 years in older adults. In contrast to previous research, the study did not find a direct link between brain atrophy and cognitive decline in people with T2D.
Researchers have discovered a new therapeutic avenue for treating type 2 diabetes by targeting the interaction between hormone-sensitive lipase (HSL) and a transcription factor responsible for fatty acid synthesis. Decreasing HSL expression leads to improved insulin sensitivity, which may help prevent or manage the disease.
A large Nordic study found liraglutide reduces the risk of myocardial infarction, stroke, or cardiovascular death among type 2 diabetes patients. The study also showed a lower risk of cardiovascular death and any cause of death with liraglutide treatment.
Research reveals an increased risk of ill health in people with evening preference, including erratic eating patterns and consumption of unhealthy foods. The study also found that glucose levels increase when night owls eat shortly before bed, negatively affecting metabolism.
The project aims to improve diabetes management for Latinos through telementoring sessions, empowering primary care providers with advanced training. La Clínica del Pueblo and George Washington University launched the first ECHO site in the region to address high diabetes prevalence and long waitlists.
A study of over 143,000 female nurses found that rotating night shift work and an unhealthy lifestyle significantly increase the risk of type 2 diabetes. The risk is higher than the sum of individual factors, suggesting an interaction between the two.
Researchers found that non-invasive skin autofluorescence measurement can predict future risk of type 2 diabetes, cardiovascular disease, and mortality. A single measurement was associated with a 3-fold increase in risk of type 2 diabetes or CVD.
A global study predicts a 20% increase in insulin use by 2030 due to rising type 2 diabetes cases. Without improved access, nearly half of the 79 million adults with type 2 diabetes will not receive insulin.
Researchers have created an oral formulation of semaglutide, a successful type 2 diabetes therapy, that can be more readily absorbed in the stomach. This development has the potential to improve treatment flexibility and patient adherence to T2D treatment programs, offering patients a less invasive route of administration.
Research suggests moderate coffee consumption may reduce type 2 diabetes risk by 25%, with potential mechanisms including antioxidant and anti-inflammatory effects. The Institute for Scientific Information on Coffee reports findings from a meta-analysis of 30 studies involving over 1.1 million participants.
A study led by St. Michael's Hospital researchers found that empagliflozin significantly reduces left ventricular mass index, a key indicator of heart disease. The medication has profound cardiovascular benefits, including improved cardiac structure and reduced mortality rates in people with Type 2 diabetes and heart disease.
Research reveals epigenetic changes in IGFBP2 gene influence type 2 diabetes risk. Higher IGFBP2 levels in blood lower diabetes risk.
A new study from the University of Eastern Finland found that poor aerobic fitness in children is associated with a higher risk of type 2 diabetes and cardiovascular disease. The study's findings suggest that traditional measures of aerobic fitness may overestimate its role in identifying children at increased risk.
Researchers identified 14 genetic variants associated with fat storage patterns and their impact on metabolic risk. These genetic factors tend to protect against diabetes, heart disease, and hypertension when stored under the skin, rather than in organs like the liver.
A new report suggests that addressing chronic diseases like diabetes could save tens of billions of dollars in healthcare costs annually. Proper nutrition therapy and exercise can effectively cause remission of Type 2 diabetes, with a one percent decrease in HbA1c levels resulting in significant savings.
Researchers found a link between colectomy and increased risk of developing type 2 diabetes. The study, analyzing data from over 46,000 patients, suggests the colon plays a crucial role in regulating blood sugar levels.
A plant-based diet has been shown to improve psychological wellbeing, reduce risk factors for type 2 diabetes, and slow nerve damage. Participants who followed a vegan diet lost nearly twice as much weight and had lower blood glucose levels compared to those on other diets.
Lifestyle interventions, medication, and surgery can effectively delay or prevent type 2 diabetes in the majority of patients, but limited access to these treatments is a major issue. Evidence-based interventions show that weight loss through lifestyle changes or metabolic surgery can reduce the risk of diabetes by up to 78%.
A new study published by the American Academy of Ophthalmology suggests that taking metformin, a common diabetes medication, can lower the risk of age-related macular degeneration. Researchers found that patients who took metformin had half as many cases of AMD compared to those who did not.
Researchers at Sahlgrenska Academy discovered that gut microbiota in people with type 2 diabetes produces a substance impairing insulin response. This finding highlights the importance of diet and gut microbiota interaction in understanding metabolism in health and disease.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that midlife women transitioning to menopause have a higher risk of developing metabolic syndrome. The study identified central obesity as the most common factor, but also showed that physically active women were less likely to deve...
A study of over 10,000 participants with type 2 diabetes found that intensive blood sugar control and targeting low blood pressure reduced the risk of macroalbuminuria, but had no impact on more significant kidney outcomes. The use of fenofibrate to lower cholesterol increased the risk for doubling of serum creatinine.
A new study found that fasting hyperglucagonemia in type 2 diabetes is associated with higher waist-to-hip ratio, poor glycemic control, and increased insulin concentrations. Visceral fat deposition may play a role in the development of this condition.
Among pediatric patients aged 20 or younger, there was a notable increase in vertical sleeve gastrectomy and a decrease in laparoscopic Roux-en-Y gastric bypass procedures between 2005-2014. The use of adjustable gastric bands also decreased during this time period, reflecting trends seen in adult metabolic bariatric surgery procedures.
A recent GWAS analysis of latent autoimmune diabetes in adults (LADA) has uncovered new connections to type 1 and type 2 diabetes, suggesting a hybrid nature of the disorder. The study found that genetic signals linked to LADA were mainly shared with established variants known to be linked to T1D.
Bariatric surgery was associated with a lower risk of macrovascular disease events at five years of follow-up compared to usual medical care. The findings suggest that bariatric surgery may help reduce patient risk, but more confirmation is needed in randomized clinical trials.
A large prospective cohort study found that higher levels of prolactin in women are associated with a lower risk of developing type 2 diabetes. Women with the highest 25% of prolactin levels were 27% less likely to develop T2D than those in the lowest 25%. The association was similar regardless of menopausal status and other risk factors.
A study of over 60,000 adults found that higher biomarker levels for dairy fat consumption are associated with a lower risk of developing type 2 diabetes. The researchers suggest re-examining the metabolic benefits of dairy fat, but note limitations and potential biases in their findings.
A new study suggests that planned intermittent fasting can help reverse type 2 diabetes by cutting out the need for insulin treatment and controlling blood glucose levels. Three men with type 2 diabetes were able to stop taking insulin after following a fasting regimen for around 10 months.
Scientists have discovered a way to restore normal insulin cell function in type 2 diabetes by blocking a protein called VDAC1. The study showed that the substance can prevent the development of the disease and improve glucose control. Further studies are needed, but the findings offer new hope for treatment options.
The new guidelines update previous recommendations, prioritizing patient-centric care, medication adherence, and lifestyle management. They also highlight the importance of metabolic surgery, metformin as first-line therapy, and personalized medication selection based on patient preferences and comorbidities.
A new study found that 21% of individuals with insulin-treated diabetes diagnosed after age 30 have severe insulin deficiency, characteristic of late-onset type 1 diabetes. These patients often experience delays in diagnosis and treatment due to misdiagnosis as type 2 diabetes.
A study funded by NIH found that gastric banding is as effective as metformin in stabilizing disease for people with prediabetes or new-onset type 2 diabetes. Participants who underwent gastric banding surgery lost significantly more weight and showed similar improvements in insulin sensitivity compared to those taking metformin.
A Japanese study found that increased fasting glucose, higher BMI, and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes. The study suggests that elevated metabolic markers for diabetes may be detectable more than 20 years before its diagnosis.
Researchers found that lixisenatide slowed the progression of kidney damage in patients with macro-albuminuria and type 2 diabetes. The study showed a statistically significant reduction in urinary albumin-to-creatinine ratio and a borderline significant reduction in risk of incidence of macroalbuminuria.
The study found large regional variations in diabetes prevalence, with North America and the Caribbean having high current rates, while Africa has low rates despite moderate obesity. If obesity rates are reduced by 25%, millions of cases of diabetes can be prevented, especially in Africa.
A new study published in The Lancet found that albiglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events by 22% in patients with type 2 diabetes and established cardiovascular disease. This result is comparable to traditional cardiovascular drugs.
A study found that a gene variant commonly associated with Type 2 diabetes may also increase the risk of being lean, contradicting common assumptions about obesity and diabetes. Researchers analyzed data from over 9,000 Hispanic Latinos and used complex modeling to estimate the odds of developing Type 2 diabetes across time.
A large observational study found that individuals with diabetes are at a higher risk of developing certain cancers, including colorectal and breast cancer. The study also showed that people with diabetes who are diagnosed with cancer have poorer survival rates compared to those without diabetes.
A new study has found a strong association between diabetes and an increased risk of developing osteoarthritis, rheumatoid arthritis, and osteoporosis. People with diabetes were 33% more likely to suffer from osteoarthritis than their counterparts without diabetes.
A large observational study found that adults with type 2 diabetes are at greater risk of dying from cancer, particularly obesity-related cancers. Non-obesity related cancers also pose a significant threat to individuals with type 2 diabetes.
A new study found that younger age at diagnosis, higher body mass index, and a maternal family history of diabetes are associated with faster disease progression in type 2 diabetes. The research used data from the UK BioBank to identify these factors and their impact on disease progression.
Research reveals that women with versus without prediabetes experience significantly larger adverse differences in cardiometabolic health compared to men. Women with prediabetes had higher blood pressure, worse cholesterol profiles, and increased inflammation before the onset of type 2 diabetes.
Research shows that weight gain between childhood and adulthood increases type 2 diabetes risk more than a stable high body mass index. Children who were overweight at age 10 and remained so have lower T2D risk compared to those who were normal weight but became overweight later in life.
Researchers found significant reductions in mean glucose and other glycemic factors when adding dapagliflozin to metformin or insulin in patients with type 2 diabetes. Greater improvements were seen in patients taking metformin compared to insulin.
A new study reveals that diuretic drug use in individuals with type 2 diabetes is associated with a significantly increased risk of serious problems in their lower limbs, leading to amputation. The research found that diuretics should be used cautiously in patients at risk of amputations.
Researchers found that SHBG levels at baseline can predict insulin resistance years later in both men and women. Lower SHBG levels are associated with higher insulin resistance, a precursor to type 2 diabetes.
A new study suggests that weight loss can put type 2 diabetes into remission by improving pancreatic beta cell function. Nearly half of participants who lost fat from around the liver and pancreas achieved diabetes remission, compared to six in the control group.
A large meta-analysis of over 191,000 postmenopausal women found that early menopause and premature ovarian failure are associated with a higher risk of developing type 2 diabetes. Women who begin menopause before age 40 are 50% more likely to develop the disease than those with normal menopause between ages 45-55.
A new study reveals that gastric bypass surgery reduces all-cause mortality risk by 49% and cardiovascular disease risk by 34% in obese patients with type 2 diabetes. However, it also increases the risk of anaemia, malnutrition, and psychiatric diagnoses.
A recent study has shown that adding genetic factors to existing risk assessments can help predict future major coronary events in people with type 2 diabetes. The genetic score provides a significant improvement in correctly predicting cardiovascular risk, particularly when used early in life.
Researchers found that online participants lost an average of 10.3 pounds at 6 months and 8.8 pounds at 12 months, comparable to in-person program results. The online program also showed better participation rates than the in-person program.
A new genomic study reveals five distinct groups of DNA sites driving unique forms of type 2 diabetes, with potential implications for personalized treatment approaches. The research identifies subtypes based on genetics and physiology, which could help physicians tailor interventions to individual patients.
A new study reveals that changes in white matter regions of the brain associated with small vessel disease are linked to decreased processing speed in people with Type 2 diabetes. Higher blood pressure and worse kidney function also contribute to poorer cognition.
A new study from the University of Iowa found that 8.5% of American adults have been diagnosed with type 2 diabetes, while 0.5% have type 1 diabetes. Type 2 diabetes is overwhelmingly more common, accounting for 91.2% of all diagnosed cases.