Articles tagged with Type 2 Diabetes
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Researchers at UT Southwestern Medical Center identified a critical link between obesity and type 2 diabetes, finding that insulin delivery is impeded due to abnormal immunoglobulins. The study may lead to new strategies for diabetes risk screening and prevention.
A study published in Diabetes Care found that diabetes-related mortality in Germany is higher than expected, with approximately 21% of all deaths attributable to the disease. The majority of deaths occurred among older adults, and men had a significantly higher number of preventable excess deaths compared to women.
A new test predicts which people with type 2 diabetes will benefit from weight loss surgery. The DiaBetter score and percentage weight loss two years post-surgery are key predictors of T2D remission.
African-American women with type 2 diabetes are disproportionately affected by ER-negative breast cancers. The study found a statistically significant association between type 2 diabetes and increased risk of ER-negative breast cancer in black women, particularly those with lower BMI.
African American women with type 2 diabetes have a higher risk of developing estrogen receptor negative (ER-) breast cancer, a more aggressive form of the disease. Chronic inflammation from diabetes may contribute to this increased risk, which could help explain the higher incidence of ER- breast cancer in African American women.
A new study from McGill University Health Centre found that women with gestational diabetes and high blood pressure are 15-37 times more likely to develop type 2 diabetes and hypertension, respectively. The risk also affects fathers, particularly when they share similar lifestyle habits with their partners.
Research finds that workplace bullying and violence increase the risk of type 2 diabetes for both men and women. The study, published in Diabetologia, suggests that these negative interpersonal relationships can activate stress responses and contribute to metabolic changes and obesity.
A recent study published in Diabetologia found that a diet rich in antioxidants, particularly from fruits and vegetables, tea, and moderate alcohol consumption, is associated with a lower risk of type 2 diabetes. Women with the highest antioxidant scores had a 27% reduced risk compared to those with the lowest scores.
A Yale-led research team has discovered how a very low calorie diet rapidly reverses type 2 diabetes in animal models. The study found that the diet lowers glucose production by decreasing conversion of lactate and amino acids into glucose, liver glycogen conversion to glucose, and fat content.
A study of 90 adults with type 2 diabetes found female gender, elevated blood sugar levels, neuropathic pain, and fatigue to be linked to sleep disturbance. Clinicians should prioritize females in sleep-related assessments and include symptoms like pain and fatigue in comprehensive evaluations.
A new study reveals that up to 97.3% of people with pancreatic disease are misdiagnosed with Type 2 diabetes, instead of the correct condition, Type 3c diabetes. This can lead to delayed treatment and devastating long-term effects for patients.
Long-term statin use is associated with a 30% increased risk of developing type 2 diabetes in susceptible individuals, according to a large study. The findings held true regardless of the clinical criteria used to determine the need for treatment.
Exosomes secreted by cells in healthy individuals stop protein aggregation that leads to type 2 diabetes, but those in patients with the disease do not. This discovery provides new insights into the disease and may lead to the development of treatments.
The oral semaglutide formulation resulted in significant improvements in glycemic control, with up to 90% of patients achieving an HbA1c level below 7%. Clinically relevant weight loss was also observed in up to 71% of patients.
A study published in JAMA found that the semaglutide pill resulted in better glycemic control than placebo over 26 weeks, with significant reductions in HbA1c levels. The oral formulation of semaglutide also showed comparable safety and weight loss benefits compared to the injectable form.
A commercial weight management program delivered by Weight Watchers helped more than half of patients at risk of developing type 2 diabetes to reduce their risk or get their blood sugar levels back to normal. The program led to significant reductions in diabetes risk, with an average fall in HbA1c levels and notable weight loss.
A new study published in The Lancet Diabetes & Endocrinology suggests that a diet rich in omega-6 polyunsaturated fats may significantly reduce the risk of developing type 2 diabetes. Researchers found that individuals with higher levels of linoleic acid, the major omega-6 fat, had a lower chance of developing type 2 diabetes.
Researchers discovered that muscle cell lipid composition varies with the time of day, influenced by a biological clock, which could help regulate insulin sensitivity. This variation is linked to type 2 diabetes development.
A Chinese study found very low rates of blood glucose monitoring among nearly 19,000 patients with type 2 diabetes before and after initiating basal insulin treatment. The data showed an increase in mean SMBG frequency after 6 months, but the percentage of patients who never monitored their blood glucose remained high.
Researchers at Joslin Diabetes Center identified PKC-delta as a natural protective factor that works against chronic inflammation in diabetes, which can lead to cardiovascular disease. The study found that PKC-delta suppresses the population of macrophages and inhibits a biological pathway that protects cells from dying.
A new study found that individuals with type 2 diabetes may experience modest deficits in cortical bone, which can increase the risk of fractures. The research highlights the importance of addressing skeletal deficits in individuals with diabetes to reduce fracture risk.
A new study published in the Journal of Bone and Mineral Research found that older adults with type 2 diabetes have deficits in cortical bone microarchitecture, increasing their risk of fractures. This is particularly concerning for hip fractures, which are a significant public health problem.
A global study of over 800 patients with Type 1 diabetes found that dapagliflozin, a Type 2 diabetes medicine, significantly improved blood sugar levels. The results demonstrate the drug's efficacy as an adjunct therapy to insulin, reducing A1C levels by more than 0.5% without severe hypoglycemia.
A new study confirms an association between sodium intake and the development of type 2 diabetes (T2D), with a 65% increase in risk for each extra gram consumed per day. The effect is even greater for Latent Autoimmune Diabetes in Adults (LADA), with a 82% rise in risk.
New research reveals 30% of type 2 diabetic patients don't begin insulin when initially recommended, with a 2-year average delay. This delay leads to worsening disease progression and increased risk factors.
Researchers found that metabolic fingerprints from blood samples linked diet and nutrient biomarkers to type 2 diabetes risk in older women. Diet was shown to be a strong predictor of the disease, with fish, whole grains, and vegetable oils found to be protective.
Higher milk and low-fat dairy consumption was associated with a lower VAT/SCAT ratio, indicating more favorable abdominal fat distribution. Additionally, daily servings of low-fat dairy were linked to higher body lean mass, suggesting a possible mechanism for reducing obesity-related metabolic disorders.
A low-calorie diet has been shown to reverse Type 2 diabetes by reducing liver and pancreatic fat content, allowing insulin production to resume. The reversal of diabetes remains possible for up to 10 years after onset with sustained weight loss.
New research suggests that eating six meals per day improves blood sugar control and reduces hunger in obese individuals with impaired glucose tolerance or type 2 diabetes. The study found that the six-meal plan decreased glycated haemoglobin levels, post-oral glucose tolerance test blood glucose levels, and abnormally high insulin lev...
Weight loss of around 15 kg can reverse type 2 diabetes, extending life expectancy and reducing healthcare costs. However, remission is rarely recorded due to lack of agreed criteria and guidance.
A recent study suggests that consuming large amounts of artificial sweeteners can alter the body's response to glucose, increasing the risk of developing type 2 diabetes. The study found that just two weeks of supplementation with artificial sweeteners was enough to enhance glucose absorption and increase blood glucose levels.
A recent study found 60 gene variants that affect hemoglobin A1c levels, including one variant unique to African Americans. This variant can reduce the accuracy of A1c blood testing, increasing the risk of underdiagnosis in a population already disproportionately affected by type 2 diabetes.
A new non-surgical device has shown promising results as an NHS treatment for people with type 2 diabetes and obesity. After one year, participants lost significant weight, had improved blood sugar control and reduced systolic blood pressure, with high patient satisfaction levels.
Patients with type 2 diabetes have lower risks of aortic aneurysm (28% reduction) and aortic dissection (47% reduction). Long-term mortality rates are also decreased after hospitalization for AA, but not AD.
A Virginia Tech research team found that oleuropein, an olive-derived compound, helps the body secrete more insulin and detoxify amylin, a signaling molecule linked to type 2 diabetes. This discovery could lead to new strategies to fight obesity and related diseases.
A new study presents evidence that taking aspirin twice daily could provide more cardiovascular benefits for individuals with type 2 diabetes. The research found that platelet aggregation increased over the standard 24-hour dosing interval when aspirin was only taken once daily, suggesting a need for antiplatelet treatment that covers ...
A new study published in Diabetologia found that cognitive behavioral group therapy (CBGT) is no better than standard care at preventing weight regain after dieting in people with type 2 diabetes. CBGT aimed to change thought patterns and behaviors, but failed to improve cardiovascular risk factors or psychological wellbeing.
A genetic variant found in African-Americans significantly reduces the accuracy of the HbA1c blood test used to diagnose and monitor type 2 diabetes. This means around 650,000 African Americans could have undiagnosed type 2 diabetes if tested with the HbA1c test alone.
A new study found that people of black or mixed ethnicities, as well as those from lower socioeconomic status, are less likely to have consistent monitoring for diabetes and its complications. The research suggests that these disparities may worsen existing ethnic and socioeconomic inequalities in diabetes outcomes.
Studies suggest having an obese spouse substantially increases a man's risk of developing type 2 diabetes, while women with an obese partner are not at increased risk. The research highlights the importance of screening spouses for diabetes if obesity is found in one person.
A new study found that hospital admission for non-alcoholic fatty liver disease (NAFLD) significantly raises the risk of cardiovascular disease and death in individuals with type 2 diabetes. NAFLD was associated with a 62% increase in incident cardiovascular events and a 40% increased risk of cardiovascular death.
A study found that a coffee compound called cafestol improves cell function and insulin sensitivity in laboratory mice, potentially spurring the development of new Type 2 diabetes treatments. Daily consumption of cafestol may delay the onset of diabetes in humans, according to researchers.
A meta-analysis of over 68,000 patients found that PCSK9 inhibitors did not increase the short-term risk of developing type 2 diabetes. However, exploratory analyses suggested a trend towards increased risk in patients with intense LDL cholesterol reduction and long-term treatment.
Regular and early lifestyle modifications, including healthy diet, lifestyle, and physical activity, can significantly reduce the risk of developing type 2 diabetes and cardiovascular disease in young South Asians. The study found that interventions starting before age 18 were more effective than those starting later.
Studies on red raspberries found that consuming the fruit may improve glucose control and reduce hunger. Researchers also discovered that red raspberry consumption can alter gut microbiota and show promise in reducing inflammation and obesity risk.
Three large trials found that screening for type 2 diabetes and cardiovascular risk factors does not reduce mortality in the general population, but individuals diagnosed with diabetes experience reduced mortality rates. The studies suggest that benefits to the general population may be increased by targeting screening to those at grea...
A new tool developed by Kaiser Permanente researchers can identify diabetes patients at high risk of severe hypoglycemia-related emergency department or hospital visits. The tool categorizes patients into three risk levels based on six variables, and has been validated with data from over 1.3 million members.
A high-intensity exercise program combined with a diet plan resulted in improved blood glucose levels among adults with type 2 diabetes. The study found that 73.5% of lifestyle participants required fewer glucose-lowering medications, compared to 26.4% in the standard care group.
A new study from McMaster University highlights the importance of public health messaging to South Asian women who are considering pregnancy. The research found that a healthy diet and pre-pregnancy weight can significantly decrease gestational diabetes risk, with approximately one-third of cases preventable.
Researchers emphasize the importance of primary prevention for Type 2 Diabetes patients to reduce heart disease risk, highlighting the need for evidence-based guidelines and lifestyle management strategies. Proven medical therapies and lifestyle interventions can significantly reduce cardiovascular burden among these patients.
Using metformin to treat patients with prediabetes could save the US healthcare system approximately $20 per patient each year. The medication is underused, with only 0.7% of eligible patients currently prescribed it.
Research examines how gastric emptying rates affect postprandial glucose levels and incretin hormone secretion. The study reveals the gastrointestinal tract's contribution to insulin regulation in individuals with type 2 diabetes.
A Wayne State University researcher is leading a clinical research study to develop a better understanding of type 2 diabetes in obesity and improve therapy for veterans and others with the disease. The study aims to characterize a cohort of obese people with and without Type 2 diabetes to distinguish different genetic subtypes.
A multicenter trial will assess the effectiveness of bariatric surgery compared to medical and lifestyle therapy for treating Type 2 diabetes. The study aims to identify clinical predictors of diabetes remission and relapse, with data collected from 302 patients over seven years.
New research suggests that educating patients' immune cells with cord blood stem cells may help combat type 1 and 2 diabetes. The therapy is safe and effective in improving islet beta cell function, making it a potential treatment for other autoimmune diseases.
Researchers discovered a molecular signature in patients who responded to the anti-asthma drug amlexanox, which showed significant improvements in blood glucose levels. The study reveals a potential new therapeutic approach for treating type 2 diabetes and identifies key gene changes associated with the beneficial effects.
A new report predicts that diabetes cases will continue to rise in sub-Saharan Africa, overwhelming health systems and crippling patients' finances. The economic cost of diabetes is expected to more than double, reaching up to $59.3 billion per year by 2030.
Research from the University of Leicester and EarthSense reveals associations between air pollution and type 2 diabetes in a large cross-sectional study. Demographic factors largely explained the association, but the study suggests continued research into potential long-term exposure factors.
Recent clinical trials suggest using medications that control blood glucose while reducing cardiovascular risk can improve patient outcomes. This approach may be more effective than current treatments, which prioritize blood sugar maintenance alone.
A new study found that concentrated broccoli sprout extract can significantly reduce fasting blood glucose levels in type 2 diabetes patients. The researchers used a computational approach to identify compounds that could counter disease-associated gene expression changes associated with the condition.