Articles tagged with Type 2 Diabetes
A new study published in Diabetologia found that women who develop gestational diabetes (GDM) during pregnancy are at double the risk of cardiovascular disease (CVD) compared to those without GDM. The study also revealed that this increased risk remains even if women with GDM do not go on to develop type 2 diabetes.
Individuals taking statins may experience higher insulin levels and insulin resistance, leading to a greater risk of developing type 2 diabetes. The analysis found a 38% increased risk among those who used statins for 15 years or more.
Researchers have developed an app that uses a smartphone camera and photoplethysmography signal to detect diabetes, showing promise for early detection and encouraging further testing by healthcare providers. The app was tested on over 54,000 individuals and correctly identified people with diabetes in over 72% of cases.
A randomized controlled trial found that resistance training and aerobic training plus resistance training significantly reduced the incidence of type 2 diabetes. The study showed that these exercise programs can be as effective as isolated aerobic training in preventing overt type 2 diabetes.
A randomized clinical trial found that a behavioral intervention with counseling sessions improved sustained physical activity and reduced sedentary behavior in patients with type 2 diabetes. The study compared the intervention to standard care with general physician recommendations.
A plant-based meal has been shown to increase the postprandial secretion of insulin and incretin hormones, particularly GLP-1, in individuals with type 2 diabetes. This improvement in beta-cell function parameters suggests a potential solution for managing and treating the condition.
A new study suggests the Affordable Care Act's requirements on pre-existing conditions and age clauses had a significant impact on adults with diabetes. The percentage of people with private health insurance who had diabetes increased after the ACA provisions began, especially among those in their 50s.
Research by University of Sydney researchers reveals a significant association between diabetes and low back pain and neck pain. The study found people with diabetes have a higher risk of experiencing these conditions, warranting further investigation into the link.
A new study published in Circulation Research found that eating nuts, particularly tree nuts, can lower the risk of cardiovascular disease among people with type 2 diabetes. The research showed that even small amounts of nuts had a significant impact on heart health.
A Texas A&M-led study reveals that estrogen can decrease insulin resistance and glucose production, reducing Type 2 diabetes incidences. The study highlights the importance of estrogen receptor signaling and Foxo1-mediated gluconeogenesis in regulating glucose homeostasis.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
A large-scale study has identified 28 novel genomic regions linked to type 2 diabetes in the Japanese population, including variants not found in European populations. The findings may lead to targeted therapeutic measures for preventing or treating diabetes in this ethnic group.
Researchers have developed a new risk score that takes into account genetic information to identify babies at high risk of type 1 diabetes. The score is nearly twice as efficient as existing methods and also effective at predicting type 1 diabetes in adults, helping with early diagnosis and treatment.
Patients with type 1 diabetes and poor blood sugar control face a higher risk of fragility fracture compared to those with good glycemic control. Good blood sugar control is an important goal for patients with diabetes, and research shows that it may help reduce the risk of fractures in type 1 diabetes patients.
A promising compound TTP399 targets glucokinase protein implicated in type 2 diabetes, improving glycemic control and reducing liver fat. Phase 2 clinical trial of 190 participants shows no adverse effects, paving way for potential new treatment options.
A study found that couples interventions for individuals with type 2 diabetes can reduce partners' diabetes distress and increase marital satisfaction. The intervention also improved diastolic blood pressure, but had no significant impact on weight loss or diet and activity behaviors.
A new study published in Cell Metabolism suggests that energy balance - the calories consumed versus burned - may not determine the development of gestational diabetes. Women with obesity tend to develop gestational diabetes due to primary risk factors such as excess fat and insulin resistance, which can be evident early in pregnancy.
A new study found that eating one egg per day is associated with a blood metabolite profile linked to a lower risk of type 2 diabetes. Researchers identified several biochemical compounds in blood that predicted a higher risk of developing the disease, including tyrosine.
A Northwestern Medicine study found that sulfonylureas and basal insulin increase the risk of heart attack, stroke, and amputation in patients with Type 2 diabetes. The study suggests a paradigm shift in treatment, recommending newer diabetes medications with more favorable cardiovascular profiles.
A large-scale genomic analysis found a strong link between type 2 diabetes and erectile dysfunction, suggesting that living a healthier lifestyle may help reduce risk. The study identified a genetic predisposition to type 2 diabetes as a cause of erectile dysfunction.
A recent study on Australian diabetics aged under 50 reveals an alarming rise in end-stage kidney disease, underscoring the need for aggressive risk factor treatment. The research highlights the importance of early intervention to mitigate this trend and alleviate pressure on Australia's kidney dialysis services.
A study of French women found that those experiencing migraines had a lower risk of developing type 2 diabetes compared to those without migraines. The observational study included over 74,000 women and suggests potential underlying causes for the association between migraines and type 2 diabetes.
A new study published in Diabetologia found that type 2 diabetes is associated with a decline in verbal memory and fluency over 5 years in older adults. In contrast to previous research, the study did not find a direct link between brain atrophy and cognitive decline in people with T2D.
Researchers have discovered a new therapeutic avenue for treating type 2 diabetes by targeting the interaction between hormone-sensitive lipase (HSL) and a transcription factor responsible for fatty acid synthesis. Decreasing HSL expression leads to improved insulin sensitivity, which may help prevent or manage the disease.
A large Nordic study found liraglutide reduces the risk of myocardial infarction, stroke, or cardiovascular death among type 2 diabetes patients. The study also showed a lower risk of cardiovascular death and any cause of death with liraglutide treatment.
Research reveals an increased risk of ill health in people with evening preference, including erratic eating patterns and consumption of unhealthy foods. The study also found that glucose levels increase when night owls eat shortly before bed, negatively affecting metabolism.
The project aims to improve diabetes management for Latinos through telementoring sessions, empowering primary care providers with advanced training. La Clínica del Pueblo and George Washington University launched the first ECHO site in the region to address high diabetes prevalence and long waitlists.
A study of over 143,000 female nurses found that rotating night shift work and an unhealthy lifestyle significantly increase the risk of type 2 diabetes. The risk is higher than the sum of individual factors, suggesting an interaction between the two.
Researchers found that non-invasive skin autofluorescence measurement can predict future risk of type 2 diabetes, cardiovascular disease, and mortality. A single measurement was associated with a 3-fold increase in risk of type 2 diabetes or CVD.
A global study predicts a 20% increase in insulin use by 2030 due to rising type 2 diabetes cases. Without improved access, nearly half of the 79 million adults with type 2 diabetes will not receive insulin.
Researchers have created an oral formulation of semaglutide, a successful type 2 diabetes therapy, that can be more readily absorbed in the stomach. This development has the potential to improve treatment flexibility and patient adherence to T2D treatment programs, offering patients a less invasive route of administration.
Research suggests moderate coffee consumption may reduce type 2 diabetes risk by 25%, with potential mechanisms including antioxidant and anti-inflammatory effects. The Institute for Scientific Information on Coffee reports findings from a meta-analysis of 30 studies involving over 1.1 million participants.
A study led by St. Michael's Hospital researchers found that empagliflozin significantly reduces left ventricular mass index, a key indicator of heart disease. The medication has profound cardiovascular benefits, including improved cardiac structure and reduced mortality rates in people with Type 2 diabetes and heart disease.
Research reveals epigenetic changes in IGFBP2 gene influence type 2 diabetes risk. Higher IGFBP2 levels in blood lower diabetes risk.
A new study from the University of Eastern Finland found that poor aerobic fitness in children is associated with a higher risk of type 2 diabetes and cardiovascular disease. The study's findings suggest that traditional measures of aerobic fitness may overestimate its role in identifying children at increased risk.
Researchers identified 14 genetic variants associated with fat storage patterns and their impact on metabolic risk. These genetic factors tend to protect against diabetes, heart disease, and hypertension when stored under the skin, rather than in organs like the liver.
A new report suggests that addressing chronic diseases like diabetes could save tens of billions of dollars in healthcare costs annually. Proper nutrition therapy and exercise can effectively cause remission of Type 2 diabetes, with a one percent decrease in HbA1c levels resulting in significant savings.
Researchers found a link between colectomy and increased risk of developing type 2 diabetes. The study, analyzing data from over 46,000 patients, suggests the colon plays a crucial role in regulating blood sugar levels.
A plant-based diet has been shown to improve psychological wellbeing, reduce risk factors for type 2 diabetes, and slow nerve damage. Participants who followed a vegan diet lost nearly twice as much weight and had lower blood glucose levels compared to those on other diets.
Lifestyle interventions, medication, and surgery can effectively delay or prevent type 2 diabetes in the majority of patients, but limited access to these treatments is a major issue. Evidence-based interventions show that weight loss through lifestyle changes or metabolic surgery can reduce the risk of diabetes by up to 78%.
A new study published by the American Academy of Ophthalmology suggests that taking metformin, a common diabetes medication, can lower the risk of age-related macular degeneration. Researchers found that patients who took metformin had half as many cases of AMD compared to those who did not.
Researchers at Sahlgrenska Academy discovered that gut microbiota in people with type 2 diabetes produces a substance impairing insulin response. This finding highlights the importance of diet and gut microbiota interaction in understanding metabolism in health and disease.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that midlife women transitioning to menopause have a higher risk of developing metabolic syndrome. The study identified central obesity as the most common factor, but also showed that physically active women were less likely to deve...
A study of over 10,000 participants with type 2 diabetes found that intensive blood sugar control and targeting low blood pressure reduced the risk of macroalbuminuria, but had no impact on more significant kidney outcomes. The use of fenofibrate to lower cholesterol increased the risk for doubling of serum creatinine.
A new study found that fasting hyperglucagonemia in type 2 diabetes is associated with higher waist-to-hip ratio, poor glycemic control, and increased insulin concentrations. Visceral fat deposition may play a role in the development of this condition.
Among pediatric patients aged 20 or younger, there was a notable increase in vertical sleeve gastrectomy and a decrease in laparoscopic Roux-en-Y gastric bypass procedures between 2005-2014. The use of adjustable gastric bands also decreased during this time period, reflecting trends seen in adult metabolic bariatric surgery procedures.
A recent GWAS analysis of latent autoimmune diabetes in adults (LADA) has uncovered new connections to type 1 and type 2 diabetes, suggesting a hybrid nature of the disorder. The study found that genetic signals linked to LADA were mainly shared with established variants known to be linked to T1D.
Bariatric surgery was associated with a lower risk of macrovascular disease events at five years of follow-up compared to usual medical care. The findings suggest that bariatric surgery may help reduce patient risk, but more confirmation is needed in randomized clinical trials.
A large prospective cohort study found that higher levels of prolactin in women are associated with a lower risk of developing type 2 diabetes. Women with the highest 25% of prolactin levels were 27% less likely to develop T2D than those in the lowest 25%. The association was similar regardless of menopausal status and other risk factors.
A study of over 60,000 adults found that higher biomarker levels for dairy fat consumption are associated with a lower risk of developing type 2 diabetes. The researchers suggest re-examining the metabolic benefits of dairy fat, but note limitations and potential biases in their findings.
A new study suggests that planned intermittent fasting can help reverse type 2 diabetes by cutting out the need for insulin treatment and controlling blood glucose levels. Three men with type 2 diabetes were able to stop taking insulin after following a fasting regimen for around 10 months.
Scientists have discovered a way to restore normal insulin cell function in type 2 diabetes by blocking a protein called VDAC1. The study showed that the substance can prevent the development of the disease and improve glucose control. Further studies are needed, but the findings offer new hope for treatment options.
The new guidelines update previous recommendations, prioritizing patient-centric care, medication adherence, and lifestyle management. They also highlight the importance of metabolic surgery, metformin as first-line therapy, and personalized medication selection based on patient preferences and comorbidities.
A Japanese study found that increased fasting glucose, higher BMI, and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes. The study suggests that elevated metabolic markers for diabetes may be detectable more than 20 years before its diagnosis.
A new study found that 21% of individuals with insulin-treated diabetes diagnosed after age 30 have severe insulin deficiency, characteristic of late-onset type 1 diabetes. These patients often experience delays in diagnosis and treatment due to misdiagnosis as type 2 diabetes.
A study funded by NIH found that gastric banding is as effective as metformin in stabilizing disease for people with prediabetes or new-onset type 2 diabetes. Participants who underwent gastric banding surgery lost significantly more weight and showed similar improvements in insulin sensitivity compared to those taking metformin.
Researchers found that lixisenatide slowed the progression of kidney damage in patients with macro-albuminuria and type 2 diabetes. The study showed a statistically significant reduction in urinary albumin-to-creatinine ratio and a borderline significant reduction in risk of incidence of macroalbuminuria.
The study found large regional variations in diabetes prevalence, with North America and the Caribbean having high current rates, while Africa has low rates despite moderate obesity. If obesity rates are reduced by 25%, millions of cases of diabetes can be prevented, especially in Africa.
A new study published in The Lancet found that albiglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events by 22% in patients with type 2 diabetes and established cardiovascular disease. This result is comparable to traditional cardiovascular drugs.
A study found that a gene variant commonly associated with Type 2 diabetes may also increase the risk of being lean, contradicting common assumptions about obesity and diabetes. Researchers analyzed data from over 9,000 Hispanic Latinos and used complex modeling to estimate the odds of developing Type 2 diabetes across time.