Articles tagged with Type 2 Diabetes
A global study of 12 million people found diabetes increases the risk of heart failure, with a significant increase for women. Women with type 1 diabetes have a 47% greater excess risk of heart failure compared to men, highlighting the need for sex-specific research.
A new study finds that diabetes confers a greater excess risk of heart failure in women than men, with type 1 diabetes associated with a 47% higher risk. The study suggests several potential explanations for this difference, including sex differences in diabetes management and cardiovascular risk factors.
A UK study found that diabetes patients experiencing greater empathy from their PCPs had a lower risk of all-cause mortality over 10 years. Patients with higher scores on the consultation and relational empathy (CARE) questionnaire reported better clinical outcomes.
A recent study found that metformin use was associated with a significantly lower risk of dementia in African American patients with type 2 diabetes. The study included data from over 73,000 male veterans and showed modest to no association between metformin and lower risk for dementia in white patients.
Researchers found that mice eating a high-fat diet who fasted every other day had reduced pancreatic fat and lower blood sugar levels. This suggests that intermittent fasting may be a therapeutic approach to prevent type 2 diabetes by reducing fat accumulation in the pancreas.
A study in the Journal of Diabetes Investigation reveals that adults with type 2 diabetes are at a higher risk of dying from cancer compared to the general population. The research found that cancer accounted for 27.8% of deaths among those with type 2 diabetes, while heart disease was the leading cause in the general population.
A collaborative study by Connecticut researchers shows that food insecurity is linked to insulin resistance and the development of type 2 diabetes in Latinos. The study found that households with food-insecure individuals had higher levels of inflammation, stress hormones, and insulin resistance compared to those who were food secure.
Researchers at Ohio State University report a significant reversal of metabolic syndrome in over half of participants after just four weeks on a low-carb diet. Despite no weight loss, the low-carb diet improved triglyceride levels and cholesterol readings, and increased fat-burning efficiency.
A UK study published in Diabetologia found that obesity during pregnancy is associated with a 3.5 times increased risk of type 2 diabetes in the child, while being overweight increases this risk by 40%. The study suggests strategies to reduce obesity and overweight in women of reproductive age are urgently needed.
Researchers at Chalmers University of Technology found that fatty fish provide clear protection against type 2 diabetes, but only if they are free from environmental pollutants. The study used innovative methods to analyze data and identified biomarkers in blood samples to objectively measure fish consumption.
Two new trials show oral semaglutide is more effective than subcutaneous liraglutide in treating type 2 diabetes, with the latest trial showing it's also safe for patients with moderate renal impairment. Another trial found that insulin degludec plus liraglutide is a durable therapy option for type 2 diabetes.
A study of adults and youth with type 2 diabetes found that improvements in insulin release wane after treatment stops, highlighting the need for continued treatment. In contrast, youth experience more aggressive disease progression during and after treatment.
A large international clinical trial found that dulaglutide reduced cardiovascular events by 12% and kidney disease by 15% in people with Type 2 diabetes. The study, REWIND, followed over 9,900 participants for five years.
Researchers used exosomes to detect microRNAs targeting carbohydrate metabolism in obese teens. The study found a link between altered adipocyte-derived exosomal microRNAs and progression from obese normoglycemia to hyperglycemia/diabetes.
Research from Nutrition 2019 reveals that consuming more plant-based foods can lower the risk of type 2 diabetes by 60 percent. Additionally, studies found that vitamins B2 and B6 may also play a role in preventing the disease. Furthermore, changing the order of food consumption can help reduce blood sugar levels after eating.
A large NIH-funded study found that taking a daily vitamin D supplement does not prevent type 2 diabetes in adults at high risk. The study, which enrolled over 2,400 participants, found no significant difference between those who took 4,000 IU of vitamin D and those who took a placebo.
The American Heart Association and the Heart Failure Society of America issue a statement on managing both conditions, highlighting lifestyle modifications and multidisciplinary care teams. The guidelines emphasize the importance of coordinated treatment to improve patient outcomes.
A study from Joslin Diabetes Center found that removing senescent beta-cells can recover their function and improve glucose metabolism in mice with insulin resistance. The researchers hope to develop a potential treatment using senolytics, which target aging cells contributing to disease dysfunction.
A Rutgers-led study concludes that bariatric surgery is an effective treatment for adolescents with obesity, as long as they can maintain a healthy lifestyle afterward. The procedure has been shown to remit type 2 diabetes and other complications of obesity in teens.
Research found that three months of high-intensity interval training improved heart function in adults with type 2 diabetes without medication changes. High-intensity exercise reversed some changes in heart function that precede diabetic heart disease.
A large international consortium analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. The study identified four genes with rare variants that affect diabetes risk, providing potential targets for new medicines and guiding researchers to better understand the disease.
A study funded by the NIH found that early weight-loss surgery in youth can lead to remission of type 2 diabetes and high blood pressure, compared to waiting until later in life. Teens who underwent gastric bypass surgery showed significant improvements in blood glucose control and reduced medication use.
A large Chinese study found that type 2 diabetes is associated with an elevated risk of 11 types of cancer in men and 13 types of cancer in women. The study, which examined data from over 410,000 adults, revealed significant increases in cancer risk for both men and women with diabetes.
Research suggests that children with high BMI in childhood are at increased risk of developing type 2 diabetes, but this risk disappears if they don't become obese adults. A meta-analysis of over 25,000 children found associations between BMI and type 2 diabetes were not influenced by educational or lifestyle factors.
A study by the University of Exeter found that 38% of patients with type 1 diabetes over 30 were initially treated as type 2. Half of those misdiagnosed remained so 13 years later. Insulin treatment is crucial for type 1 diabetes diagnosis.
A clinical trial found liraglutide, an existing adult diabetes medication, effectively treats Type 2 diabetes in children. The study showed a significant reduction in A1C levels and improvements in glycated hemoglobin levels, offering new treatment options for this age group.
A new study from the University of Exeter Medical School found that using characteristics such as weight and age at diagnosis can help select the best diabetes drug for individuals. This approach is more effective than previous models, which divide adults with diabetes into subgroups.
Researchers discovered seven genetic variants linked to type 2 diabetes in young people, with one variant novel to youth. The study used data from a large pediatric cohort and found that obesity-related variants contribute to the risk of developing Type 2 diabetes in younger individuals.
A Johns Hopkins study found that few American adults eligible for diabetes prevention programs are being referred to or participating in these programs. Despite the high health and economic burden of type 2 diabetes, only 4.2 percent of those at risk were referred to a program, with even lower participation rates overall.
A randomized crossover trial found time-restricted eating improved glucose control, regardless of when the men chose to stop eating. The study's results suggest modulating meal times can improve glucose control and may lead to weight loss.
Research at Lund University explores how lifestyle affects gene activity in human tissues, including adipose tissue, skeletal muscle, pancreatic islets, liver, and blood. The study reveals the role of epigenetic changes in disease development and potential novel treatments.
Research highlights the association between chronic obstructive pulmonary disease (COPD) and type 2 diabetes, emphasizing the importance of collaborative care to address underlying systemic inflammation. Achieving optimal glucose control is crucial in patients with coexistent T2 DM and COPD.
A new study led by McGill University Health Centre researchers found that children born to mothers with gestational diabetes are nearly twice as likely to develop type 1 diabetes before the age of 22. Early detection is crucial in preventing complications like diabetic ketoacidosis.
Children born to mothers with gestational diabetes are nearly twice as likely to develop diabetes before age 22. Early detection is crucial, as many cases are diagnosed when symptoms like frequent urination and weight loss arise.
A landmark clinical trial shows that canagliflozin lowers the risk of kidney failure by 30% in people with Type 2 diabetes and kidney disease. The study also found a significant reduction in cardiovascular events, providing a promising new treatment option for patients at high risk.
Researchers found a link between prostate medicines and increased risk of type 2 diabetes in men taking 5-alpha-reductase inhibitors. Men on these medications should be monitored for warning signs of diabetes and have their prescriptions adjusted if necessary.
A UBC study found that a high-fat, low-carb breakfast can prevent large blood sugar spikes and improve glycemic control. Participants with well-controlled Type 2 Diabetes experienced reduced glucose exposure and improved stability of glucose readings after consuming a low-carb breakfast.
A new molecule, EPB-53, has been discovered to increase FGF21 levels in the liver and plasma through oral administration. This could lead to new therapeutic strategies for treating type 2 diabetes and non-alcoholic fatty liver disease.
Research found that people diagnosed with type 2 diabetes before age 40 have a significantly increased risk of death, stroke, heart attack, and other cardiovascular conditions. Women under 40 are at higher risk than men, while the risk decreases with increasing age of diagnosis.
A new UBC study found that consuming just one dose of carbohydrates while on a high-fat, low-carbohydrate diet can damage blood vessels. The researchers recruited nine healthy young males and had them consume a glucose drink before and after a seven-day keto diet, revealing biomarkers in the blood suggesting vessel wall damage.
Research suggests that spending large amounts of time sitting down increases the risk of cardiovascular disease, type 2 diabetes, and death. The study estimated that sedentary behaviour is associated with 11.6% of all deaths in the UK, with 69,276 potential deaths avoided if sedentary behaviour were eliminated.
A study found that community pharmacy-based type 2 diabetes screening is cost-effective and can increase early diagnoses by 3.3 years. Researchers suggest targeting high-risk patients to improve the service's cost-effectiveness.
A recent study found that moderate muscle mass reduces the risk of type 2 diabetes by 32 percent. The benefits were independent of cardiorespiratory fitness, and higher levels of muscle strength did not provide additional protection. Building strength with resistance exercise may be a helpful way to prevent type 2 diabetes.
A new study published in Diabetologia found that women who develop gestational diabetes (GDM) during pregnancy are at double the risk of cardiovascular disease (CVD) compared to those without GDM. The study also revealed that this increased risk remains even if women with GDM do not go on to develop type 2 diabetes.
Individuals taking statins may experience higher insulin levels and insulin resistance, leading to a greater risk of developing type 2 diabetes. The analysis found a 38% increased risk among those who used statins for 15 years or more.
Researchers have developed an app that uses a smartphone camera and photoplethysmography signal to detect diabetes, showing promise for early detection and encouraging further testing by healthcare providers. The app was tested on over 54,000 individuals and correctly identified people with diabetes in over 72% of cases.
A randomized controlled trial found that resistance training and aerobic training plus resistance training significantly reduced the incidence of type 2 diabetes. The study showed that these exercise programs can be as effective as isolated aerobic training in preventing overt type 2 diabetes.
A randomized clinical trial found that a behavioral intervention with counseling sessions improved sustained physical activity and reduced sedentary behavior in patients with type 2 diabetes. The study compared the intervention to standard care with general physician recommendations.
A plant-based meal has been shown to increase the postprandial secretion of insulin and incretin hormones, particularly GLP-1, in individuals with type 2 diabetes. This improvement in beta-cell function parameters suggests a potential solution for managing and treating the condition.
Research by University of Sydney researchers reveals a significant association between diabetes and low back pain and neck pain. The study found people with diabetes have a higher risk of experiencing these conditions, warranting further investigation into the link.
A new study suggests the Affordable Care Act's requirements on pre-existing conditions and age clauses had a significant impact on adults with diabetes. The percentage of people with private health insurance who had diabetes increased after the ACA provisions began, especially among those in their 50s.
A new study published in Circulation Research found that eating nuts, particularly tree nuts, can lower the risk of cardiovascular disease among people with type 2 diabetes. The research showed that even small amounts of nuts had a significant impact on heart health.
A Texas A&M-led study reveals that estrogen can decrease insulin resistance and glucose production, reducing Type 2 diabetes incidences. The study highlights the importance of estrogen receptor signaling and Foxo1-mediated gluconeogenesis in regulating glucose homeostasis.
A recent study published in Diabetologia found that three-quarters of individuals with type 2 diabetes who underwent Roux-en-Y gastric bypass surgery experienced diabetes remission within one year. The research also identified predictors for success, including lower glycated haemoglobin levels and male patients, as well as a reduced ri...
A large-scale study has identified 28 novel genomic regions linked to type 2 diabetes in the Japanese population, including variants not found in European populations. The findings may lead to targeted therapeutic measures for preventing or treating diabetes in this ethnic group.
Researchers have developed a new risk score that takes into account genetic information to identify babies at high risk of type 1 diabetes. The score is nearly twice as efficient as existing methods and also effective at predicting type 1 diabetes in adults, helping with early diagnosis and treatment.
Patients with type 1 diabetes and poor blood sugar control face a higher risk of fragility fracture compared to those with good glycemic control. Good blood sugar control is an important goal for patients with diabetes, and research shows that it may help reduce the risk of fractures in type 1 diabetes patients.
A promising compound TTP399 targets glucokinase protein implicated in type 2 diabetes, improving glycemic control and reducing liver fat. Phase 2 clinical trial of 190 participants shows no adverse effects, paving way for potential new treatment options.
A study found that couples interventions for individuals with type 2 diabetes can reduce partners' diabetes distress and increase marital satisfaction. The intervention also improved diastolic blood pressure, but had no significant impact on weight loss or diet and activity behaviors.
A new study published in Cell Metabolism suggests that energy balance - the calories consumed versus burned - may not determine the development of gestational diabetes. Women with obesity tend to develop gestational diabetes due to primary risk factors such as excess fat and insulin resistance, which can be evident early in pregnancy.