Articles tagged with Type 2 Diabetes
A recent study found 60 gene variants that affect hemoglobin A1c levels, including one variant unique to African Americans. This variant can reduce the accuracy of A1c blood testing, increasing the risk of underdiagnosis in a population already disproportionately affected by type 2 diabetes.
A new non-surgical device has shown promising results as an NHS treatment for people with type 2 diabetes and obesity. After one year, participants lost significant weight, had improved blood sugar control and reduced systolic blood pressure, with high patient satisfaction levels.
Patients with type 2 diabetes have lower risks of aortic aneurysm (28% reduction) and aortic dissection (47% reduction). Long-term mortality rates are also decreased after hospitalization for AA, but not AD.
A new study found that hospital admission for non-alcoholic fatty liver disease (NAFLD) significantly raises the risk of cardiovascular disease and death in individuals with type 2 diabetes. NAFLD was associated with a 62% increase in incident cardiovascular events and a 40% increased risk of cardiovascular death.
A new study found that people of black or mixed ethnicities, as well as those from lower socioeconomic status, are less likely to have consistent monitoring for diabetes and its complications. The research suggests that these disparities may worsen existing ethnic and socioeconomic inequalities in diabetes outcomes.
Studies suggest having an obese spouse substantially increases a man's risk of developing type 2 diabetes, while women with an obese partner are not at increased risk. The research highlights the importance of screening spouses for diabetes if obesity is found in one person.
A study found that a coffee compound called cafestol improves cell function and insulin sensitivity in laboratory mice, potentially spurring the development of new Type 2 diabetes treatments. Daily consumption of cafestol may delay the onset of diabetes in humans, according to researchers.
A meta-analysis of over 68,000 patients found that PCSK9 inhibitors did not increase the short-term risk of developing type 2 diabetes. However, exploratory analyses suggested a trend towards increased risk in patients with intense LDL cholesterol reduction and long-term treatment.
Regular and early lifestyle modifications, including healthy diet, lifestyle, and physical activity, can significantly reduce the risk of developing type 2 diabetes and cardiovascular disease in young South Asians. The study found that interventions starting before age 18 were more effective than those starting later.
Studies on red raspberries found that consuming the fruit may improve glucose control and reduce hunger. Researchers also discovered that red raspberry consumption can alter gut microbiota and show promise in reducing inflammation and obesity risk.
Three large trials found that screening for type 2 diabetes and cardiovascular risk factors does not reduce mortality in the general population, but individuals diagnosed with diabetes experience reduced mortality rates. The studies suggest that benefits to the general population may be increased by targeting screening to those at grea...
A new tool developed by Kaiser Permanente researchers can identify diabetes patients at high risk of severe hypoglycemia-related emergency department or hospital visits. The tool categorizes patients into three risk levels based on six variables, and has been validated with data from over 1.3 million members.
A high-intensity exercise program combined with a diet plan resulted in improved blood glucose levels among adults with type 2 diabetes. The study found that 73.5% of lifestyle participants required fewer glucose-lowering medications, compared to 26.4% in the standard care group.
A new study from McMaster University highlights the importance of public health messaging to South Asian women who are considering pregnancy. The research found that a healthy diet and pre-pregnancy weight can significantly decrease gestational diabetes risk, with approximately one-third of cases preventable.
Researchers emphasize the importance of primary prevention for Type 2 Diabetes patients to reduce heart disease risk, highlighting the need for evidence-based guidelines and lifestyle management strategies. Proven medical therapies and lifestyle interventions can significantly reduce cardiovascular burden among these patients.
Using metformin to treat patients with prediabetes could save the US healthcare system approximately $20 per patient each year. The medication is underused, with only 0.7% of eligible patients currently prescribed it.
Research examines how gastric emptying rates affect postprandial glucose levels and incretin hormone secretion. The study reveals the gastrointestinal tract's contribution to insulin regulation in individuals with type 2 diabetes.
A Wayne State University researcher is leading a clinical research study to develop a better understanding of type 2 diabetes in obesity and improve therapy for veterans and others with the disease. The study aims to characterize a cohort of obese people with and without Type 2 diabetes to distinguish different genetic subtypes.
New research suggests that educating patients' immune cells with cord blood stem cells may help combat type 1 and 2 diabetes. The therapy is safe and effective in improving islet beta cell function, making it a potential treatment for other autoimmune diseases.
A multicenter trial will assess the effectiveness of bariatric surgery compared to medical and lifestyle therapy for treating Type 2 diabetes. The study aims to identify clinical predictors of diabetes remission and relapse, with data collected from 302 patients over seven years.
Researchers discovered a molecular signature in patients who responded to the anti-asthma drug amlexanox, which showed significant improvements in blood glucose levels. The study reveals a potential new therapeutic approach for treating type 2 diabetes and identifies key gene changes associated with the beneficial effects.
A new report predicts that diabetes cases will continue to rise in sub-Saharan Africa, overwhelming health systems and crippling patients' finances. The economic cost of diabetes is expected to more than double, reaching up to $59.3 billion per year by 2030.
Research from the University of Leicester and EarthSense reveals associations between air pollution and type 2 diabetes in a large cross-sectional study. Demographic factors largely explained the association, but the study suggests continued research into potential long-term exposure factors.
Recent clinical trials suggest using medications that control blood glucose while reducing cardiovascular risk can improve patient outcomes. This approach may be more effective than current treatments, which prioritize blood sugar maintenance alone.
A new study found that concentrated broccoli sprout extract can significantly reduce fasting blood glucose levels in type 2 diabetes patients. The researchers used a computational approach to identify compounds that could counter disease-associated gene expression changes associated with the condition.
A new study published in the New England Journal of Medicine found that canagliflozin significantly reduced the risk of both cardiovascular disease and kidney disease in people with type 2 diabetes. The drug was shown to lower blood sugar levels and also provide protection against heart failure and renal decline.
In a controlled study published in the Journal of the American College of Nutrition, participants who adopted a vegetarian diet lost nearly twice as much weight compared to those following a traditional diabetes diet. The study found that the plant-based diet led to greater reductions in subfascial and intramuscular fat.
A new study published in the Journal of the American College of Nutrition found that vegetarian diets are more effective than conventional low-calorie diets in reducing body weight. Vegetarian diets also improve glucose and lipid metabolism, which is particularly important for people with metabolic syndrome and type 2 diabetes.
A randomized trial found that self-monitoring of blood glucose levels in patients with non-insulin-treated type 2 diabetes did not improve glycemic control or health-related quality of life after one year. The study suggested that SMBG should not be routine for most patients, contradicting existing practice.
A six-month text messaging program improved blood sugar levels in low-income Hispanics with Type 2 diabetes, rivaling some glucose-lowering medications. The study found that participants who engaged more with the messages had better A1C measures.
A new study found that spousal engagement in healthy diet planning and shared glycemic control activities can help manage type 2 diabetes. Positive religious coping by the nondiabetic spouse is also linked to higher levels of shared activities, while negative coping is associated with lower participation.
Fatty acid esters disrupt insulin synthesis and lead to beta cell dysfunction in type 2 diabetes. High-resolution mass spectrometry imaging reveals an imbalance in insulin production and secretion, affecting the function of pancreatic islets.
A new study found that SGLT2 inhibitors increase the risk of diabetic ketoacidosis by twice as much as another class of diabetes medications. Despite being rare, this complication can be fatal if left untreated.
A newly discovered mechanism behind reduced insulin production in type 2 diabetes reveals that insulin-producing cells regress and become immature, reducing their function. The study identifies key genes, including SOX5, which affects disease progression and suggests potential new treatments targeting cellular maturity.
Researchers at Duke University have created a technology that fuses GLP1 with a heat-sensitive elastin-like polypeptide, providing glucose control up to three times longer than current treatments. The new biopolymer injection lasts more than two weeks in primates and has the potential to replace daily or weekly insulin shots.
Researchers found that people with type 2 diabetes have bacteria that penetrate the mucus lining of their colon, leading to insulin resistance and abnormal blood glucose levels. The study's results provide a new understanding of how metabolic diseases like diabetes develop.
Research found that women exposed to colder temperatures during pregnancy had a lower rate of gestational diabetes compared to those exposed to hotter temperatures. The study also discovered that for every 10-degree Celsius rise in temperature, women were six to nine percent more likely to develop gestational diabetes.
Researchers have identified 111 new chromosome locations associated with type 2 diabetes susceptibility in a large-scale study. The new loci were found to regulate the expression of at least 266 genes that neighbour the disease sites.
Researchers found that resveratrol supplementation reduced aortic stiffness by up to 9.1 percent in patients with high arterial stiffness, but the effect was not significant in those with normal aortic stiffness. Resveratrol may activate the longevity gene SIRT1 as a potential mechanism for its effects.
Researchers developed a personalized algorithm that predicts the impact of specific foods on an individual's blood sugar levels. The algorithm has been integrated into an app, Glucoracle, allowing individuals with type 2 diabetes to make better nutritional choices.
A new study found that overweight and obese individuals with early stage type 2 diabetes have more severe and progressive brain structure and cognition abnormalities compared to normal-weight participants. The research suggests that managing insulin resistance may be crucial in preserving brain function.
Researchers developed a personalized algorithm that predicts the impact of particular foods on an individual's blood sugar levels. The Glucoracle app allows users to upload food and blood measurements, providing real-time predictions of post-meal blood sugar levels.
A new study finds that exposure to mildly cold or warm environments can increase metabolism and energy expenditure, helping tackle obesity. The research also shows increased insulin sensitivity in patients with type 2 diabetes after 10 days of intermittent cold exposure.
A Swedish study reveals a significant decrease in cardiovascular disease incidence among individuals with type 1 and type 2 diabetes, with reductions of up to 50% compared to the general population. The study attributes this improvement to advances in diabetes care and prevention strategies.
A new study has found that children with obesity are four times more likely to develop type 2 diabetes by age 25 compared to their normal-weight counterparts. The study examined data from over 369,000 children and teenagers in the UK and found a significant increase in type 2 diabetes cases between 1994 and 2013.
A large-scale UK study has found that children with obesity face four times the risk of developing type 2 diabetes compared to those in the normal BMI range. The study examined data from over 369,000 children and found no association between obesity and increased incidence of type 1 diabetes.
A new study on UHT milk has found a link between protein clusters and age-related diseases like Alzheimer
A new study found that plant protein was associated with a lower risk of type 2 diabetes, while persons with a diet rich in meat had a higher risk. Replacing animal protein with plant protein can reduce diabetes risk by 18% daily.
Researchers developed a prognostic tool predicting end-stage renal disease risk in type 1 and 2 diabetes patients. The test uses biomarker values to identify those at high risk, improving the efficiency and cost-effectiveness of clinical trials.
The study found that incidence of type 1 diabetes increased by 1.8% annually from 2002 to 2012, while type 2 diabetes rose at a rate of 4.8%. Racial/ethnic minority groups experienced the most significant increases in new diagnosed cases.
A new study found that adding a third oral antihyperglycemic agent to metformin and sitagliptin can improve glycemic control in type 2 diabetes patients, overcoming 'clinical inertia' and allowing more than 60% of patients to reach the target HbA1c level. The study, which included over 7,800 participants, also found that the addition o...
Researchers discovered a link between indolepropionic acid and reduced risk of type 2 diabetes. A diet rich in whole grain products and dietary fibre boosts indolepropionic acid production, promoting insulin secretion by pancreatic beta cells.
Researchers identified markers of aging in insulin-producing beta cells, revealing diverse populations with different lifespans. Insulin resistance accelerates beta cell aging, contributing to type 2 diabetes development.
Researchers have discovered a unique metabolic signature in the urine of diabetic, obese black teenagers that may become a way to predict the development of type 2 diabetes. Levels of serotonin metabolites were found to be lower in those with diabetes, while other metabolites were higher.
A study of 260 individuals with type 2 diabetes found that night shift workers had poorer glycemic control, despite adjusting for factors like diet and sleep duration. The research highlights the need for special attention to managing diabetes in this population through healthy habits and medication use.
A study of people with type 2 diabetes found that those with a later sleep-wake time preference reported more depression symptoms, regardless of sleep quality. The findings support an association between circadian regulation and psychological functioning in patients with type 2 diabetes.
The PREDIMED study reveals a protective association between legume consumption, especially lentils, and the risk of developing subsequent type 2 diabetes. Legumes rich in B vitamins and fibre help improve human health and lower blood glucose levels slowly after consumption.
Researchers used mass spectrometric methods to identify proteins influenced by SNPs relevant to type 2 diabetes and AMD. This study provides insights into the molecular mechanisms modulated by regulatory SNPs, contributing to personalized medicine.
A new study found that intensive medical treatment using oral medications, insulin, and lifestyle therapies can reverse type 2 diabetes in up to 40% of participants. The study's findings support the notion that type 2 diabetes can be reversed, at least in the short term, with medical approaches.
A new study aims to identify factors that result in long-term diabetes remission and better blood sugar control after bariatric surgery. Researchers will follow up with approximately 242 patients over five years to analyze hormone secretion, metabolism, and complications.