Articles tagged with Type 2 Diabetes
Research found that women exposed to colder temperatures during pregnancy had a lower rate of gestational diabetes compared to those exposed to hotter temperatures. The study also discovered that for every 10-degree Celsius rise in temperature, women were six to nine percent more likely to develop gestational diabetes.
Researchers have identified 111 new chromosome locations associated with type 2 diabetes susceptibility in a large-scale study. The new loci were found to regulate the expression of at least 266 genes that neighbour the disease sites.
Researchers found that resveratrol supplementation reduced aortic stiffness by up to 9.1 percent in patients with high arterial stiffness, but the effect was not significant in those with normal aortic stiffness. Resveratrol may activate the longevity gene SIRT1 as a potential mechanism for its effects.
Researchers developed a personalized algorithm that predicts the impact of particular foods on an individual's blood sugar levels. The Glucoracle app allows users to upload food and blood measurements, providing real-time predictions of post-meal blood sugar levels.
Researchers developed a personalized algorithm that predicts the impact of specific foods on an individual's blood sugar levels. The algorithm has been integrated into an app, Glucoracle, allowing individuals with type 2 diabetes to make better nutritional choices.
A new study found that overweight and obese individuals with early stage type 2 diabetes have more severe and progressive brain structure and cognition abnormalities compared to normal-weight participants. The research suggests that managing insulin resistance may be crucial in preserving brain function.
A new study finds that exposure to mildly cold or warm environments can increase metabolism and energy expenditure, helping tackle obesity. The research also shows increased insulin sensitivity in patients with type 2 diabetes after 10 days of intermittent cold exposure.
A large-scale UK study has found that children with obesity face four times the risk of developing type 2 diabetes compared to those in the normal BMI range. The study examined data from over 369,000 children and found no association between obesity and increased incidence of type 1 diabetes.
A Swedish study reveals a significant decrease in cardiovascular disease incidence among individuals with type 1 and type 2 diabetes, with reductions of up to 50% compared to the general population. The study attributes this improvement to advances in diabetes care and prevention strategies.
A new study has found that children with obesity are four times more likely to develop type 2 diabetes by age 25 compared to their normal-weight counterparts. The study examined data from over 369,000 children and teenagers in the UK and found a significant increase in type 2 diabetes cases between 1994 and 2013.
A new study on UHT milk has found a link between protein clusters and age-related diseases like Alzheimer
A new study found that plant protein was associated with a lower risk of type 2 diabetes, while persons with a diet rich in meat had a higher risk. Replacing animal protein with plant protein can reduce diabetes risk by 18% daily.
Researchers developed a prognostic tool predicting end-stage renal disease risk in type 1 and 2 diabetes patients. The test uses biomarker values to identify those at high risk, improving the efficiency and cost-effectiveness of clinical trials.
The study found that incidence of type 1 diabetes increased by 1.8% annually from 2002 to 2012, while type 2 diabetes rose at a rate of 4.8%. Racial/ethnic minority groups experienced the most significant increases in new diagnosed cases.
A new study found that adding a third oral antihyperglycemic agent to metformin and sitagliptin can improve glycemic control in type 2 diabetes patients, overcoming 'clinical inertia' and allowing more than 60% of patients to reach the target HbA1c level. The study, which included over 7,800 participants, also found that the addition o...
Researchers discovered a link between indolepropionic acid and reduced risk of type 2 diabetes. A diet rich in whole grain products and dietary fibre boosts indolepropionic acid production, promoting insulin secretion by pancreatic beta cells.
Researchers identified markers of aging in insulin-producing beta cells, revealing diverse populations with different lifespans. Insulin resistance accelerates beta cell aging, contributing to type 2 diabetes development.
Researchers have discovered a unique metabolic signature in the urine of diabetic, obese black teenagers that may become a way to predict the development of type 2 diabetes. Levels of serotonin metabolites were found to be lower in those with diabetes, while other metabolites were higher.
A study of 260 individuals with type 2 diabetes found that night shift workers had poorer glycemic control, despite adjusting for factors like diet and sleep duration. The research highlights the need for special attention to managing diabetes in this population through healthy habits and medication use.
A study of people with type 2 diabetes found that those with a later sleep-wake time preference reported more depression symptoms, regardless of sleep quality. The findings support an association between circadian regulation and psychological functioning in patients with type 2 diabetes.
The PREDIMED study reveals a protective association between legume consumption, especially lentils, and the risk of developing subsequent type 2 diabetes. Legumes rich in B vitamins and fibre help improve human health and lower blood glucose levels slowly after consumption.
Researchers used mass spectrometric methods to identify proteins influenced by SNPs relevant to type 2 diabetes and AMD. This study provides insights into the molecular mechanisms modulated by regulatory SNPs, contributing to personalized medicine.
A new study found that intensive medical treatment using oral medications, insulin, and lifestyle therapies can reverse type 2 diabetes in up to 40% of participants. The study's findings support the notion that type 2 diabetes can be reversed, at least in the short term, with medical approaches.
A new study aims to identify factors that result in long-term diabetes remission and better blood sugar control after bariatric surgery. Researchers will follow up with approximately 242 patients over five years to analyze hormone secretion, metabolism, and complications.
A new study suggests that low gluten diets may increase the risk of developing type 2 diabetes. Researchers analyzed data from over 199,000 participants and found that those who consumed more gluten had lower risk of type 2 diabetes during a 30-year follow-up period.
A new model of care has been associated with a higher uptake of insulin treatment among patients with type 2 diabetes, reports a study published in The BMJ. By focusing on an enhanced role for practice nurses, the model aims to improve outcomes and reduce barriers in clinical practice.
Patients with Type 2 diabetes and acute heart failure have a significantly lower risk of death if they have high systolic blood pressure, but are more likely to be hospitalized for heart failure. The study found that those with a systolic blood pressure above 150 mmHg were 45% less likely to die, but 47% more likely to be hospitalized.
A study found that nearly half of all deaths due to heart disease, stroke, and type 2 diabetes in the US are linked to suboptimal dietary habits. The research identified specific foods and nutrients associated with cardiometabolic diseases, revealing opportunities for public health planning and strategy development.
A study published in JAMA found that nearly half of US deaths from heart disease, stroke, and type 2 diabetes are linked to inadequate diet. The main culprits were excess sodium consumption, as well as overconsumption of processed meats and sugar-sweetened beverages.
Researchers have identified 90 genes in fat cells that may contribute to obesity and cardiometabolic diseases. The study used a large dataset of Finnish men with detailed health records, revealing the effects of gene variations on human health and disease risk.
A recent study published in the Journal of the American Medical Association found that teens and young adults with type 2 diabetes are at a higher risk of developing kidney, nerve, and eye diseases. This study, funded by NIH and CDC, compared over 1,700 youth with type 1 and 272 youth with type 2 diabetes.
A recent study found that teenagers and young adults with type 2 diabetes are more likely to develop complications, such as diabetic kidney disease, retinopathy, and peripheral neuropathy, compared to those with type 1 diabetes. The study also revealed higher prevalence of hypertension in both groups.
A new study found that adolescents and young adults with type 2 diabetes experience more than double the health complications compared to those with type 1 diabetes. Health complications include retinopathy, diabetic kidney disease, peripheral neuropathy, arterial stiffness, and high blood pressure.
Researchers at the University of California San Diego found a collaborative diabetes clinic to be cost-effective, improving patient outcomes and lowering healthcare costs. The clinic's personalized medication therapy management and education led to better glycemic control and reduced medical costs for patients over three years.
Researchers found that people with severe gum disease had higher HbA1C values and were more likely to have pre-diabetes or suspected diabetes. This suggests that severe gum disease may be an early sign of undiagnosed diabetes, making screening in dental practices a feasible option.
A three-year trial by the University of Liverpool found that liraglutide 3.0 mg reduces type 2 diabetes risk by 80% in individuals with obesity and prediabetes. Participants experienced greater sustained weight loss compared to a placebo.
A long-term study found gastric band surgery improved patients' chances of diabetes remission, reduced medication needs and enhanced quality of life. The study also showed significant weight loss and low adverse events.
A single high-fat meal can reduce the body's sensitivity to insulin, leading to increased fat deposits in the liver and changes in energy metabolism. This study found that even a small amount of palm oil triggers insulin resistance, which can contribute to the development of type 2 diabetes and fatty liver disease.
Researchers found that high consumption of saturated fatty acids and animal fat increased the risk of type 2 diabetes by twofold. The study also showed that substituting saturated fats with vegetable sources like olive oil and nuts can help prevent chronic diseases.
A new study published in Diabetologia found that babies born to mothers with gestational diabetes have a higher risk of preterm birth, Caesarean section, and cardiac malformations. The study also revealed an increased risk of death for newborns born to mothers with insulin-treated gestational diabetes.
Researchers found that genetic predisposition to abdominal adiposity significantly increases the incidence of type 2 diabetes and coronary heart disease, as well as cardiovascular risk factors. The study suggests that using genetics to determine the effects of body shape on cardiometabolic outcomes could lead to new prevention strategies.
Research finds genetic predisposition to higher waist-to-hip ratio associated with increased risk of type 2 diabetes and coronary heart disease. The study suggests that body fat distribution beyond BMI measurement may explain part of the variation in cardiometabolic disease risk.
A team of researchers has identified a common regulatory grammar in islet cells that affects the activity of Regulatory Factor X, a master regulator involved in gene expression. Many Type 2 diabetes-linked DNA changes disrupt this grammar, leading to a range of health problems.
The American Diabetes Association has awarded a $1.625-million grant to develop an animal model studying the connection between gut bacteria and autoimmune attack in type 1 diabetes. The research aims to identify mechanisms that may contribute to the disease and potentially lead to treatments that prevent it.
A new study found that high levels of air pollution can make insulin-creating cells less efficient, increasing the risk for type 2 diabetes in obese Latino children. Exposure to poor air quality during childhood increases the risk for obesity and Type 2 diabetes.
A study of over 33,000 people found that preventing adult weight gain can reduce type 2 diabetes cases twice as much as targeting high-risk individuals, and that population-based strategies could prevent nearly one in five diabetes cases if everyone who gained weight maintained their weight.
The UT Southwestern Medical Center review article proposes an evidence-based medicine approach to prevent overtreatment of type 2 diabetes. It suggests balancing absolute benefits and harms with the physician's judgment and patient values, recommending more modest blood-sugar goals for frail and older individuals.
A new study found that providing nutritious meals to HIV-positive individuals and those with Type 2 diabetes improved medication adherence, reduced depression, and increased optimal blood sugar control. Participants consumed fewer fats, more fruits and vegetables, and lost weight, while also experiencing fewer symptoms of depression.
A randomized trial will investigate canagliflozin's effects on kidney function decline and provide benefits to diabetic patients. The study aims to slow kidney damage and inform treatment decisions.
A study of nearly 31,000 insured patients in the Kaiser Permanente Northern California health care system reports that nonadherence to newly prescribed diabetes medications was greater among Latino than white patients. Meanwhile, another study found a 10 percent increase in glycemic control for Latino patients who switched from languag...
A UBC study finds that one session of interval weight-training can improve blood vessel function and reduce the risk of Type 2 diabetes complications. The study demonstrates that simple leg exercises involving weights can be an effective tool to manage disease, especially for those with Type 2 diabetes.
A systematic review of screening tests and interventions for type 2 diabetes prevention found low diagnostic accuracy, with lifestyle interventions showing a 37% reduction in relative risk. Population-wide approaches may be more effective than screen and treat policies alone.
The American College of Physicians recommends prescribing metformin as the primary treatment for type 2 diabetes when medication is necessary to improve blood sugar levels. Adding a second oral medication to metformin may provide additional benefits, but the cost should be discussed with clinicians and patients.
A new study found that fenofibrate therapy may be beneficial in reducing cardiovascular events in patients with type 2 diabetes who take statins but still have high triglyceride levels and low HDL cholesterol levels. The study suggests a potential benefit of combining fenofibrate with statin treatment for this specific patient population.
A study of over 3,000 families affected by mid-20th Century China's widespread starvation found that prenatal famine exposure was associated with significantly higher odds of hyperglycemia and type 2 diabetes in both the mother and her children. The risk persisted even when only one parent had been exposed to famine.
Researchers found that moderate exercise improved spatial memory impairments in type 2 diabetic rats, possibly due to increased lactate levels and normalization of glycogen levels. Exercise also normalized MCT2 expression, which may be a key mechanism underlying the improved memory function.
A 'Sit Less' intervention, breaking up sitting with standing and light-intensity walking, significantly improved insulin sensitivity and 24-hour glucose levels compared to traditional exercise. The study found that reducing sitting time can be a more effective way to improve blood sugar control for individuals with type 2 diabetes.
Research from the University of Eastern Finland shows that even mild iron excess contributes to type 2 diabetes prevalence and incidence. Men are more at risk due to higher iron accumulation, while moderate iron levels are safer than depletion or deficiency.
Researchers have successfully reactivated oscillations in insulin-producing pancreatic beta cells using mathematical models and microfluidic devices. By delivering controlled glucose levels to dormant cells, scientists can test how insulin-producing cells get turned off and whether they can be reactivated.
Australian researchers have discovered that the platypus and echidna have evolved changes in the hormone GLP-1, making it resistant to rapid degradation. This finding has potential for developing new type 2 diabetes treatments with a long-lasting form of insulin.