The baroreceptor-inspired microneedle skin patch delivers precise and controlled drug release in response to finger touching, significantly enhancing the precision and effectiveness of treatment. Experiments using Cy3 dye and insulin as model drugs demonstrated improved delivery efficacy compared to passive methods.
Researchers have determined the location and function of natural blood-pressure barometers inside our bodies, which detect subtle changes in blood pressure and adjust hormone levels to maintain healthy blood pressure. The discovery has significant implications for developing new treatments for high blood pressure.
A new Scripps Research study reveals how specialized neurons detect changes in blood pressure and maintain cardiovascular homeostasis. The researchers identified two proteins, PIEZO1 and PIEZO2, that play a crucial role in the baroreceptor reflex, which has significant implications for treating drug-resistant hypertension.
Researchers have developed an implantable device that successfully reduced blood pressure in rats by 40% without major side effects. The device targets the vagal nerve to stimulate baroreceptors, controlling short-term blood pressure fluctuations.
Researchers at OHSU School of Dentistry discovered a molecule, BDNF, that plays a critical role in the development and regulation of blood pressure. The finding may contribute to the prevention of Sudden Infant Death Syndrome (SIDS) and high blood pressure.