Articles tagged with Neurology
Researchers at LMU identified a specific bacterial signal that shapes immune response to stroke, worsened brain injury in mice. Indole-producing bacteria acted on AHR receptor in dendritic cells, promoting protective T cells and reducing damage. The study raises potential for targeting gut microbiota to improve stroke outcome.
UC San Diego Health has adopted new coil technology and FDA-approved liquid-based treatment for chronic subdural hematoma, expanding minimally invasive treatment options. These advances provide more options for customizing treatment based on a patient's anatomy and clinical needs.
A new review found that insomnia is associated with a 26% higher risk of stroke and 28% higher odds of hospital admission. The study also linked insomnia to depression, suicidal behaviors, and dementia, particularly Alzheimer's disease.
Researchers developed an AI approach to predict glioblastoma recurrence, allowing for targeted treatments before the cancer becomes visible on MRI. The tool uses microscopic images of fresh, unprocessed tissue and scored based on tumor infiltration, with an accuracy of predicting recurrence within 5-10 millimeters of the sampled tissue.
A new study has found that having a transient ischemic attack (TIA) is associated with a higher risk of developing dementia. Researchers analyzed 113,081 people with a TIA and found that over seven years, one in five developed dementia, compared to 15% of those without a stroke or TIA.
Researchers at the University of Helsinki identified five brain profiles for depression, revealing distinct patterns of brain activity and connectivity. The study suggests that depression is not a biologically similar disease for everyone, and individualized treatment may be key to more effective care.
Researchers found that strokes among adults ages 20-54 nearly doubled over nearly three decades, even as short-term survival after stroke improved. The increase was driven by ischemic stroke, with rates rising from 23.8 cases per 100,000 person-years in 1993-1994 to 47.3 cases per 100,000 person-years in 2020.
Researchers developed a model of the primary visual cortex, introducing feedback mechanisms to constrain chaos and reduce neural activity variability. The model showed a 93 percent reduction in variability, allowing the brain to remain flexible while reliably processing visual information.
Researchers found that lower bone mineral density in the spine was associated with faster cognitive decline and accelerated age-related white matter injury. Lower bone density was also linked to specific brain regions, including the corpus callosum and the internal capsule, which support executive function.
JMIR Neurotechnology invites submissions on digital health technologies in Parkinson disease, focusing on measurement and intervention. The call for papers aims to address challenges in validation, reproducibility, and clinical integration of these measurements.
The Journal of Neurorestoratology has returned to SciOpen, a digital publishing platform with over 200 journals and 230 countries, offering a more dynamic and globally connected publishing environment. All new submissions should be made via the new ScholarOne system starting September 1, 2026.
A new brain-computer interface (BCI) allows people with vocal tract and bodily paralysis to convey both speech and upper-body gestures simultaneously. The BCI successfully translated the thoughts of patients into commands that dictated the expressions of a full-body virtual avatar.
A trial testing out-of-body experiences found no correlation with target identification, but participants unexpectedly described researchers' locations and activities. The unexpected findings may lead to the development of better evaluation methods and potentially support the case for out-of-body remote viewing.
Researchers at Johns Hopkins Medicine have developed a new approach to brain imaging that enables continuous monitoring of brain activity and disease progression for over 24 hours in freely moving mouse models. The cloud-based miniaturized microscope, CloudScope, allows scientists to access live imaging data remotely, providing a more ...
Researchers from Fudan University developed a strategy to achieve efficient engraftment of macrophages in peripheral organs using Mr BMT, a technique that replaces microglia in the CNS. The study shows that Mr BMT preserves tissue homeostasis and innate immune response, with durable macrophage replacement lasting at least 9 months.
Researchers discovered that psilocybin prevents nerve injury and associated symptoms in preclinical models, protecting sensory nerve endings and preserving touch sensation. Psilocybin may offer a new intervention for preventing chemotherapy-induced peripheral neuropathy, improving patients' quality of life.
A study published in Neurology found that immigrants in Canada have longer intensive care unit (ICU) stays after a stroke, but were admitted to the ICU at similar rates as long-term residents. Researchers suggest possible reasons for the longer stays may include language barriers and differences in attitudes toward end-of-life care.
A new study from the University of Colorado Boulder reveals how the brain's defense mechanism can backfire, forming micro-clots that damage tissue after the original clot is gone. This phenomenon, known as no reflow, affects up to 50% of stroke patients and can lead to long-term disability or death.
The Louisa Gross Horwitz Prize recognizes Dr. Huda Zoghbi and Dr. Adrian Bird for their groundbreaking work on epigenetic regulation in the nervous system. Their discoveries have led to new treatments for Rett syndrome, a severe neurodevelopmental disorder that affects girls and has previously been considered untreatable.
Adrian Bird and Huda Zoghbi's groundbreaking work on epigenetics in neurological diseases has reshaped scientists' understanding of brain disease. Their discoveries have inspired international efforts to develop genetic therapies for devastating conditions like Rett syndrome.
Research reveals that the visual systems of mice and monkeys follow the same efficient coding principle, but process different sensory inputs. This principle explains why mice have stronger responses to movement due to their coarse patch-based vision.
The updated guideline provides recommendations for preventive medications for both chronic and episodic migraine, taking into account new research and medication options. Clinicians are advised to assess the impact of migraine on quality of life when choosing a preventive medication, and to discuss the strength of evidence, possible si...
The American Academy of Neurology has launched BrainHealth.com, a public resource providing expert-reviewed information, tools, and stories to improve brain health. The website offers trustworthy guidance, practical resources, and personal stories to help people navigate brain health with confidence.
The American Academy of Neurology launches BrainHealth.com, a public resource providing expert-reviewed information, tools, and stories for brain health. The website offers evidence-based guidance and practical resources for individuals to make informed choices for their brain health at every stage of life.
University Hospitals has received American Heart Association Get With The Guidelines - Stroke awards for its commitment to ensuring timely, appropriate treatment for stroke patients. The hospital has achieved high levels of quality care, including door-to-needle times of 45 minutes or less for 75% of patients.
A new study reveals that Parkinson's disease costs Europe €22.8 billion annually, with direct medical and non-medical costs, informal care, and lost productivity contributing to the total burden. The condition's prevalence in Europe has nearly doubled since 1990, with Germany recording the highest national costs at €5.7 billion.
A new study published in Neurology found that a brain scan biomarker can predict the progression from mild cognitive impairment to dementia in people with early-onset Alzheimer's disease. The biomarker measured gray matter shrinkage in key brain areas, predicting faster progression and higher risk of dementia.
Two new studies from Karolinska Institutet suggest that inflammation and genetic factors may contribute to cluster headache, a rare neurological disorder characterized by severe headache attacks. The studies also found that exposure to substances in tobacco smoke may interact with biological mechanisms in the condition.
A new study found that standard memory tests, such as word-pair or list-learning tests, may fail to detect the real-life memory problems reported by many female breast cancer survivors after chemotherapy. Story-based tests, on the other hand, revealed significant memory difficulties in these women.
A cohort study of 544 young survivors of aneurysmal subarachnoid hemorrhage found that 30.2% developed new brain aneurysms over 40 years. Female sex, smoking, and family history of aneurysms were identified as risk factors, with smoking cessation associated with lower risk.
A new research tool, PGS-TRI, analyzes family data to understand how genetics and environment contribute to autism risk. The tool provides a more precise look at how 'nature' and 'nurture' interact within families, allowing researchers to better understand the complex factors that shape a child's health.
The FDA has cleared the PrecivityAD2 blood test, developed by C2N Diagnostics, to aid in the early diagnosis of Alzheimer's disease. The test uses high-resolution mass spectrometry to measure biomarkers associated with amyloid pathology, providing more accurate and reliable results than cerebrospinal fluid tests.
Dr. Danesh, a professor at FAU's College of Education, has made exemplary contributions to audiology through research, education, and mentorship. His work has advanced the profession and demonstrated a sustained commitment to advancing audiology.
Researchers investigated 2.5 million births in Taiwan and found no association between valproate use by fathers and neurodevelopmental disorders or malformations in children. The study's results challenge previous warnings and suggest more research is needed.
A team of researchers at Harvard University sustained brain organoids for nearly six years, demonstrating a lifelike developmental clock. The organoids showed emergence and maturation of neurons, as well as functional maturity, mirroring human brain development.
A nationwide study found that people living within 500 feet of dry cleaners had a 14% greater risk of developing Parkinson's disease compared to those living further away. The study, led by Barrow Neurological Institute, highlights the potential role of environmental exposures in disease development.
A new roadmap for stroke recovery prioritizes genetic and blood biomarkers to drive precision neuro-rehabilitation and biotherapy. The framework seeks to understand the underlying biology of brain repair after a stroke, with the goal of developing effective biotherapeutics.
Researchers discovered how anesthesia, surgery, and intensive care stress alter gene activity in the brain, leading to cognitive impairment and delirium. A new drug, vorinostat, reversed these changes, restoring memory formation and regulating the internal biological clock.
The inclusion of benzodiazepines in airline emergency medical kits is crucial for treating seizures that may occur during flights. Benzodiazepines can effectively manage seizure symptoms and prevent complications.
A study identified novel autoantibodies associated with idiopathic myelopathy, specifically those related to vitamin B12 transport. Central nervous system vitamin B12 deficiency was also found in affected individuals. The findings suggest a potential diagnostic approach for myelopathy
Researchers analyzed EBRAINS-hosted brain data to determine that whole-brain activity patterns predict stimulation outcomes better than local recordings. Targeting specific sensorimotor and visual networks reduces response variability by up to 24%. This study highlights the value of open datasets for enabling large-scale analyses.
A comparative study examines autologous pericranium and G-Patch grafts in cranial duraplasty, finding fewer complications with natural grafts but no significant difference. The study highlights the need for larger multicenter studies to determine comparative effectiveness.
Patients with severe traumatic brain injury in resource-limited settings are at higher risk of mortality. The study highlights the need for improved acute and postdischarge care to reduce mortality rates.
Researchers identified recurring metabolic changes associated with blood-brain barrier disruption, including disrupted glutamate and glutamine metabolism. These findings suggest that characteristic patterns of metabolic changes may be used to detect brain damage in the future.
Researchers developed a multiprotein approach to predict advanced tau pathology among amyloid-positive individuals, outperforming p-tau217 alone. This study suggests a scalable alternative to tau PET staging for clinical or research settings.
Researchers found that exercise-induced molecular changes contribute to neuronal health, improving movement and quality of life in PD patients. Exercise types such as aerobic exercises, resistance training, balance training, and multimodal exercise were found to be helpful in reducing falls, disabilities, and improving brain function.
Researchers used real human brain tissue samples to test the underlying mechanisms of deep brain stimulation. They found that brain cells became more synchronized in communicating, similar to memory formation, while altering gene expression across different types of brain cells.
The Barrow Neurological Institute is conducting a Phase 1/2 clinical trial investigating ibogaine as a therapeutic agent for treating traumatic brain injury (TBI). Researchers aim to enroll 40 participants and determine how effectively ibogaine addresses TBI symptoms and quality of life.
Researchers discovered that depression is associated with a specific area of the hippocampus, independent of Alzheimer's disease risk factors. The study found participants with depression had smaller volumes in the CA23DG region, which plays a crucial role in retrieving memories and distinguishing between similar experiences.
UC San Diego Health has been ranked as the top care facility in California and among the top 20 in the nation for eight medical specialties. The institution achieved this distinction through its patient-dedicated, collaborative spirit and commitment to delivering outstanding care.
Researchers used connected speech analysis to distinguish between nonfluent, logopenic and semantic PPA variants with high accuracy. The study also showed expected atrophy associations and discriminated common neuropathologic classes in an autopsy-confirmed subset.
Research suggests that an overactive immune response in the brain may play a role in Dravet Syndrome, leading to frequent seizures and developmental challenges. Blocking an inflammatory pathway called cGAS-STING-interferon signaling could lead to new therapeutic strategies for epilepsy disorders.
A new grant will support research into how strokes disrupt brain networks controlling the bladder, aiming to identify imaging biomarkers predicting treatment response. Researchers will use advanced brain imaging and non-invasive spinal stimulation to develop a personalized approach for treating bladder problems after stroke.
Researchers found two widely used blood tests accurate in detecting Alzheimer’s pathology in participants with Down syndrome. The tests, Lumipulse G p-tau217 and PrecivityAD2, offer an easier path to diagnosis for this high-risk population.
Researchers at Kennedy Krieger Institute discovered that memory consolidation during sleep depends on coordinated activity among three brain regions, disrupting this activity impairs memory performance. Epileptic spikes can also interfere with brain activity, leading to cognitive effects in patients with epilepsy.
Researchers found that brain fluid circulation depends on blood flow in the venous sinuses, and impaired lymphatic vessels lead to accumulated fluids causing pressure buildup. The study opens new avenues for refining diagnosis and improving patient care for patients with IIH.
A study published in Neurology Open Access found that Black people with multiple sclerosis (MS) die from the disease at a younger age than white people. The study also found an increasing trend of deaths related to high blood pressure among both groups, emphasizing the need for targeted interventions to control this risk factor.
A Peking University research team has developed the world's first chip that can match the functioning speed of the human brain. The chip, which operates at 50 MHz and uses in-memory computing, reduces data movement and brings high-quality brain modeling closer to real-time use.
Researchers used sEEG to examine white matter electrophysiological dynamics during working memory. Load modulates tract-specific power and cross-frequency connectivity, with distinct patterns across different brain regions.
New evidence explains why certain parts of the brain are more vulnerable to neurodegenerative diseases. The study suggests that directing therapies to specific protein forms can lead to improved treatment outcomes. Researchers found that subtle differences in protein abundance and complexes assemble determine regional vulnerability.