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Adjusting trees’ internal clocks can help them cope with climate change

A new study from Umeå University reveals that trees' circadian clocks regulate growth and seasonal events. Adjusting clock-associated genes could help trees synchronize with changing climates, improving forestry management. The study also has implications for global vegetation models predicting forest growth and carbon storage.

SourceUmea University·Journalnpj Biological Timing and Sleep·TypeExperimental study·DateApr 15, 2025

Researchers uncover role of fungal circadian clock in pathogenicity

A team of scientists has discovered that the circadian clock plays a crucial role in regulating F. oxysporum's response to zinc starvation and controlling secondary metabolism, enhancing its virulence. The study provides new insight into host-pathogen interactions and could lead to innovative approaches for crop protection.

SourceChinese Academy of Sciences Headquarters·JournalScience Advances·TypeExperimental study·DateApr 3, 2025

Crosstalk among aging, circadian rhythms, and cancers

Research highlights the interconnected relationship between aging, circadian rhythms, and cancer, with shared mechanisms including genomic instability, cellular senescence, and chronic inflammation. Modulating circadian rhythms may serve as a novel strategy to intervene in age-related functional decline and treat cancer.

SourceResearch·JournalResearch·TypeNews article·DateMar 11, 2025

Routine asthma test more reliable in the morning and has seasonal effects, say doctors

A study by Cambridge researchers found that a routine lung function test used to diagnose asthma is more reliable in the morning. The reliability of the test decreases throughout the day and differs significantly between winter and autumn, with individuals being 33% less likely to receive a positive result during autumn.

SourceUniversity of Cambridge·JournalThorax·TypeData/statistical analysis·DateMar 11, 2025

Waking up is not stressful, study finds

Researchers at the University of Bristol found no increase in cortisol release after waking, contrary to long-held assumptions. The study's findings suggest that daily cortisol rhythms may play a more significant role in regulating stress responses.

SourceUniversity of Bristol·JournalProceedings of the Royal Society B Biological Sciences·TypeObservational study·DateJan 14, 2025

How deep sleep clears a mouse’s mind, literally

Researchers discovered that norepinephrine triggers blood vessel constriction to propel cerebrospinal fluid through the brain, clearing out waste. The findings suggest that sleep aids may disrupt this process, potentially affecting long-term cognitive health.

SourceCell Press·JournalCell·TypeExperimental study·DateJan 8, 2025

Researchers unravel a novel mechanism regulating gene expression in the brain that could guide solutions to circadian and other disorders

Researchers have identified a novel mechanism controlling circadian gene expression and behavioral rhythms through chemical bonding of monoamine neurotransmitters to histone proteins. This discovery could lead to targeted therapies for conditions involving circadian rhythm disruptions, such as insomnia and depression.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalNature·TypeExperimental study·DateJan 8, 2025

Research Spotlight: Researchers reveal the influences behind timing of sleep spindle production

A study published in PNAS found that short-term timing patterns of past brain activity are the primary determinant of sleep spindle timing, accounting for over 70% of its variability. These individualized patterns change with age and provide a new target for understanding how sleep supports memory.

SourceBrigham and Women's Hospital·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateJan 7, 2025

New research reveals how the body clock regulates inflammation

Researchers at RCSI University of Medicine and Health Sciences have discovered that macrophages, a type of immune cell, work differently throughout the day due to the body's internal clock. This daily rhythm determines when immune cells are most efficient at detecting threats and mounts a response.

SourceRCSI·JournalThe FASEB Journal·DateDec 17, 2024

Unlocking the clock: The role of the circadian system in inflammatory bowel diseases

Research highlights the critical link between the body's circadian clock and inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis. Disruptions in circadian rhythms exacerbate inflammation, suggesting that aligning treatment strategies with natural biological cycles could improve patient outcomes.

SourceThe Hebrew University of Jerusalem·JournalTrends in Molecular Medicine·TypeLiterature review·DateDec 12, 2024

A blueprint for the brain's circadian clock

A team of researchers has created the first complete map of the brain's circadian clock in the fly Drosophila, revealing at least 240 neurons involved in regulating daily rhythms. This detailed mapping provides a foundation for exploring circadian dysregulation linked to health conditions such as sleep disorders and metabolic diseases.

SourceUniversity of Würzburg·JournalNature Communications·TypeImaging analysis·DateDec 5, 2024

Vanderbilt scientists discover shared genetic foundations between musical rhythm and human language

Researchers found overlapping genetic underpinnings between rhythm-related skills and language-related traits, including dyslexia. The study identified 16 regions of the genome that overlapped between rhythm and language, suggesting a complex genetic architecture shared by these fundamental human traits.

SourceVanderbilt University Medical Center·JournalNature Human Behaviour·TypeData/statistical analysis·DateNov 27, 2024

Opening a new avenue in predicting mood episodes using wearable devices: A sleep and circadian rhythm data analysis model

Researchers developed a novel model predicting mood episodes using only sleep-wake pattern data from wearable devices. The study found daily changes in circadian rhythm are key predictors of mood episodes, offering new possibilities for tracking individual changes to prevent future episodes.

SourceInstitute for Basic Science·Journalnpj Digital Medicine·TypeExperimental study·DateNov 19, 2024

New study investigates how jetlag can disrupt our metabolism

A new study by University of Surrey and University of Aberdeen researchers found that jetlag impacts metabolism, causing reduced energy spent processing meals and changes in blood sugar and fat levels. The metabolic effects are temporary, recovering within 2-3 days, while impairment of sleep and alertness takes longer to recover.

SourceUniversity of Surrey·JournaliScience·TypeRandomized controlled/clinical trial·DateNov 19, 2024

Sleep is no light matter for bees

A new study found that artificial light significantly disrupts the circadian rhythms of honey bees, leading to impaired behaviors and reduced sleep periods. This poses a threat to their essential role as pollinators, supporting ecosystem stability and global food security.

SourceUniversity of California - San Diego·JournalScientific Reports·TypeExperimental study·DateNov 12, 2024

Gut microbes play a key role in regulating stress responsiveness throughout the day, research finds

A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms. The findings open the door for developing new microbial-based therapies to help individuals better manage stress-related mental health conditions.

SourceUniversity College Cork·JournalCell Metabolism·TypeRandomized controlled/clinical trial·DateNov 5, 2024

Between night and day: The power of flies to adapt

Scientists studied Drosophila species' ability to adapt to day length fluctuations, revealing the critical role of the Pdf gene in regulating circadian plasticity. The study found that Drosophila melanogaster has a wider distribution due to its flexibility in responding to environmental changes.

SourceUniversity of Lausanne·JournalNature·TypeExperimental study·DateOct 31, 2024

Brighter nights and darker days could lead to an early grave

A study of over 13 million hours of data found that exposure to bright nights and dark days is associated with an increased risk of death. Those exposed to high levels of light at night had a 21–34% increased risk, while those exposed to high levels of daylight had a 17–34% reduction in their risk of death.

SourceFlinders University·JournalProceedings of the National Academy of Sciences·TypeData/statistical analysis·DateOct 30, 2024

Study: Time-restricted eating may improve health of adults with metabolic syndrome

A recent study found that limiting food consumption within a 10-hour window per day improved key indicators of heart health in adults with metabolic syndrome. The study demonstrated significant reductions in blood sugar and cholesterol levels, as well as lower levels of hemoglobin A1c, a marker of long-term blood sugar management.

SourceUniversity of California - San Diego·JournalAnnals of Internal Medicine·DateSep 30, 2024

Light at the end of the tunnel for night shift workers

A new study published in the SLEEP journal found that using artificial lighting synchronized to natural biological rhythms improves quality of sleep and work performance for night shift workers. Strategic exposure to light accelerated body-clock adjustment and improved alertness and performance, as well as sleep after a night shift.

SourceFlinders University·JournalSLEEP·TypeExperimental study·DateSep 26, 2024

Disturbed clocks: How eating and exercise influence the timing of our internal clocks

A study shows that eating and exercise can shift the timing of our internal clocks, with the liver clock responding to food intake and the muscle clock requiring a combination of both. This research has implications for metabolic problems like type 2 diabetes and suggests that timing of exercise may also be important.

SourceNetherlands Institute for Neuroscience - KNAW·JournalNeurobiology of Sleep and Circadian Rhythms·DateSep 19, 2024

Darwin’s longstanding interest in biological rhythms

Charles Darwin's work on biological rhythms dates back to 1838, when he observed plant leaves closing in response to touch. He also noted seasonal and daily changes in animal behavior, hibernation patterns, and tidal rhythms, demonstrating a profound engagement with chronobiology.

SourcePNAS Nexus·JournalPNAS Nexus·DateAug 27, 2024