Articles tagged with Biological Rhythms
Researchers at RCSI University of Medicine and Health Sciences have discovered that macrophages, a type of immune cell, work differently throughout the day due to the body's internal clock. This daily rhythm determines when immune cells are most efficient at detecting threats and mounts a response.
Glioblastoma brain tumors synchronize their growth with the daily release of steroid hormones like cortisol, according to new research. Blocking these signals slows tumor growth and disease progression in animal models.
Research highlights the critical link between the body's circadian clock and inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis. Disruptions in circadian rhythms exacerbate inflammation, suggesting that aligning treatment strategies with natural biological cycles could improve patient outcomes.
A team of researchers has created the first complete map of the brain's circadian clock in the fly Drosophila, revealing at least 240 neurons involved in regulating daily rhythms. This detailed mapping provides a foundation for exploring circadian dysregulation linked to health conditions such as sleep disorders and metabolic diseases.
Researchers found overlapping genetic underpinnings between rhythm-related skills and language-related traits, including dyslexia. The study identified 16 regions of the genome that overlapped between rhythm and language, suggesting a complex genetic architecture shared by these fundamental human traits.
Researchers found a strong link between depression and menstrual pain in a new study published in Briefings in Bioinformatics. Depression may be a cause of dysmenorrhea, rather than a consequence, according to the findings.
Researchers found that cyanobacteria use variations in pulse amplitude to convey information in single cells, regulating genes and controlling cellular processes. This discovery sheds light on how biological rhythms work together to coordinate cellular functions.
The Associated Professional Sleep Societies (APSS) is accepting research abstracts and session proposal submissions for SLEEP 2025. Accepted abstracts will be published online and explore topics such as machine learning, sleep and the glymphatic system, and obesity management.
A recent study published in Nutrition & Diabetes found that consuming over 45% of daily calorie intake after 5 p.m. is associated with increased glucose levels, regardless of individual weight or body fat composition. This can lead to a higher risk of type 2 diabetes, cardiovascular disease, and chronic inflammation.
Researchers developed a novel model predicting mood episodes using only sleep-wake pattern data from wearable devices. The study found daily changes in circadian rhythm are key predictors of mood episodes, offering new possibilities for tracking individual changes to prevent future episodes.
A new study by University of Surrey and University of Aberdeen researchers found that jetlag impacts metabolism, causing reduced energy spent processing meals and changes in blood sugar and fat levels. The metabolic effects are temporary, recovering within 2-3 days, while impairment of sleep and alertness takes longer to recover.
A new study found that artificial light significantly disrupts the circadian rhythms of honey bees, leading to impaired behaviors and reduced sleep periods. This poses a threat to their essential role as pollinators, supporting ecosystem stability and global food security.
A pioneering study has uncovered the vital role that gut microbiota plays in regulating stress responses by interacting with the body's circadian rhythms. The findings open the door for developing new microbial-based therapies to help individuals better manage stress-related mental health conditions.
Researchers identify interleukin-17A as a key regulator of fat storage, carrying implications for addressing obesity and preventing wasting. The discovery highlights the interaction between the immune system and circadian rhythms, which may hold therapeutic potential for metabolic disorders.
The John Innes Centre, LMU Munich, and Leiden University have secured €8.3m in funding to study circadian rhythms in non-photosynthetic bacteria, which could have significant implications for human health and the environment. The project aims to understand the properties and ecology of biological clocks across a new kingdom of life.
Scientists studied Drosophila species' ability to adapt to day length fluctuations, revealing the critical role of the Pdf gene in regulating circadian plasticity. The study found that Drosophila melanogaster has a wider distribution due to its flexibility in responding to environmental changes.
A study of over 13 million hours of data found that exposure to bright nights and dark days is associated with an increased risk of death. Those exposed to high levels of light at night had a 21–34% increased risk, while those exposed to high levels of daylight had a 17–34% reduction in their risk of death.
A clinical trial found time-restricted eating improved blood sugar regulation and reduced markers of metabolic dysfunction in adults with metabolic syndrome. Participants who followed a customized eight-to-ten-hour eating window saw significant improvements compared to standard treatments.
A recent study found that limiting food consumption within a 10-hour window per day improved key indicators of heart health in adults with metabolic syndrome. The study demonstrated significant reductions in blood sugar and cholesterol levels, as well as lower levels of hemoglobin A1c, a marker of long-term blood sugar management.
Research from UC Irvine reveals that disrupted circadian clocks accelerate colorectal cancer by altering the diversity and abundance of gut bacteria, compromising intestinal barrier function. This discovery offers new avenues for prevention and treatment strategies.
A new study published in the SLEEP journal found that using artificial lighting synchronized to natural biological rhythms improves quality of sleep and work performance for night shift workers. Strategic exposure to light accelerated body-clock adjustment and improved alertness and performance, as well as sleep after a night shift.
A new study using wearable devices and questionnaires found that people exposed to higher levels of night-time aircraft noise experienced more restlessness during sleep and disrupted daily sleep rhythm. The results suggest a link between night-time aircraft noise exposure and sleep disturbance, with potential long-term effects on health.
A study shows that eating and exercise can shift the timing of our internal clocks, with the liver clock responding to food intake and the muscle clock requiring a combination of both. This research has implications for metabolic problems like type 2 diabetes and suggests that timing of exercise may also be important.
A novel LED device with alternating orange and blue wavelengths has been shown to effectively reset circadian clocks in humans. The study found that the light outpaced other devices in advancing melatonin levels, offering a new approach to counteract seasonal affective disorder.
A Dutch study found that night owls are more likely to develop type 2 diabetes due to a disrupted circadian rhythm. Participants with late chronotypes had a 46% higher risk of T2D and increased body fat, including visceral and liver fat.
Researchers found that bacteria can anticipate the arrival of new seasons by using their internal 24-hour clocks. Samples exposed to short days showed significantly higher survival rates when plunged into ice, indicating that photoperiodism is critical in preparing bacteria for longer-term environmental changes.
Researchers discovered that cyanobacteria can anticipate seasonal changes by sensing photoperiod, promoting cold resistance and altering lipid metabolism. This adaptation may have evolved before circadian clocks, suggesting a new perspective on biological timekeeping.
Researchers found that moth species with overlapping ranges in the southeastern US have distinct clock genes, including the 'disco' gene. The study reveals how vision evolves when a species switches its pattern of activity, and provides insights into the mechanisms behind species speciation.
Charles Darwin's work on biological rhythms dates back to 1838, when he observed plant leaves closing in response to touch. He also noted seasonal and daily changes in animal behavior, hibernation patterns, and tidal rhythms, demonstrating a profound engagement with chronobiology.
A recent study published in PNAS explores how plants combine clock signals with environmental cues under naturally fluctuating conditions. The research team developed statistical models that accurately predict gene expression activity under control of circadian clock responses to environmental signals.
Researchers have identified certain times of the day when cancer cells are most responsive to medication-based treatments, suggesting personalized treatment plans could improve efficacy and reduce side effects. The study used a method called high-throughput deep phenotyping to analyze the circadian rhythms of breast cancer cell lines.
A new study from Oregon Health & Science University reveals that people who are overweight and ignore their body's signals to sleep at night experience negative health consequences. The study found sex-specific differences in health impacts, with men having higher levels of belly fat and women having higher overall body fat percentage.
A study by McGill University researchers found that the timing of malaria parasite infection affects disease severity and host response. Circadian rhythms influence vulnerability to malaria parasites, with night-time infections resulting in less severe symptoms and slower parasite spread.
A study published in Current Biology found that bouncing is the primary movement facilitating synchronization in dance, occurring independently of music and partner movements. Researchers identified two modes of synchrony: music-driven and partner-driven, with bouncing acting as a supramodal rhythm regulator.
Scientists at Washington University in St. Louis have found that altering GABA receptor density affects circadian rhythm amplitude and synchrony among SCN cells. Reducing or mutating these receptors decreased the mice's daytime wheel-running and reduced nocturnal activity.
A special issue of the Journal of the Academy of Nutrition and Dietetics explores the effects of various fasting regimens on body weight, cardiometabolic disease risk, and sleep. The study found that time-restricted eating can result in clinically meaningful weight loss and reduction in liver enzymes in adolescents with type 2 diabetes.
A Flinders University study found that exposure to brighter light at night is associated with a higher risk of developing type 2 diabetes. The research used data from approximately 85,000 people and tracked their light levels for nine years.
The study aims to understand the activation of the internal clock that regulates body processes in cluster headache patients. Researchers found a new circadian pattern of pain in a laboratory headache mouse model, which disappeared when clock genes were genetically altered.
A new study reveals that physiological synchrony significantly enhances perceived romantic attraction. Super Synchronizers, who naturally synchronize well in social and nonsocial contexts, are perceived as more romantically appealing. This study integrates experimental and observational methods to investigate the mechanisms of romantic...
A Michigan Medicine study reveals that circadian rhythms play a crucial role in mobilizing innate lymphoid cells, which defend barrier tissues. The study found that clock genes regulate the activation of these cells at different times of day.
A single episode of intense exercise reduces subsequent physical activity and body temperature in mice, leading to weight gain. The study highlights the importance of considering not only calories burned during exercise but also subsequent activity levels and circadian rhythm for effective weight loss.
The researchers created soft robots equipped with electronic skins and artificial muscles to sense their surroundings and adapt in real-time. These robots can perform various tasks, such as monitoring internal conditions, providing treatments, and delivering drugs over an extended period.
A new study found that circadian misalignment in teens is associated with increased carbohydrate intake and sedentary behavior. The research involved 377 adolescents and showed that a later sleep schedule was linked to greater carb consumption and sedentary behavior.
Researchers have identified shared genetic links between disturbed sleep, neurodevelopmental and neuropsychiatric conditions. Polygenic scores for certain conditions are associated with chronotype and insomnia, suggesting potential new therapies.
Researchers found that optimizing individual time-of-day delivery can significantly enhance the efficacy of immune checkpoint blockades in solid tumors. Proper regulation of circadian rhythms is necessary to suppress inflammation and support peak immune function.
Researchers found that plants produce electric potential in sync with their daily cycles, which can be harnessed as a renewable energy source. The study discovered that the electric streaming potential increases with decreased ion concentration and increased pH.
Researchers found that snails from tidal areas developed stronger circatidal rhythms compared to those in nontidal regions. The study suggests that environmental adaptations can influence the expression of genes controlled by biological clocks, leading to potential changes in physiological processes.
A study of 23 elderly patients with hypertension found that evening aerobic exercise improved baroreflex sensitivity, a mechanism that regulates blood pressure. This improvement led to better blood pressure regulation and reduced muscle sympathetic nerve activity, making evening exercise more effective than morning exercise.
The Sleep Research Society has recognized four individuals with its 2024 awards, honoring their exceptional contributions to sleep and circadian science, education, and public health. The winners include Dr. Elizabeth Klerman, Dr. David Raizen, Michael Perlis, and Julie Flygare.
A new study from Washington State University found that just a few days on a night shift schedule can disrupt protein rhythms related to blood glucose regulation and energy metabolism. This dysregulation may lead to chronic metabolic conditions such as diabetes and obesity.
Researchers have discovered that synchronization between the central circadian clock and peripheral clocks in muscle and skin is crucial for maintaining tissue function and preventing degenerative processes associated with aging. Time-restricted feeding can partially replace the central clock and enhance the autonomy of the muscle cloc...
A study of 25,000 NBA matches found that home teams from the Western Time Zone Area have a near 10% better win ratio when playing against Eastern Teams. The researchers suggest that elite basketball coaches and teams should consider the physical and mental effects of time zone travel on game planning.
A new study from MIT researchers has found that many genes involved in drug metabolism follow a circadian rhythm, affecting how much of a drug is available and how effectively the body breaks it down. The study's findings have implications for developing better dosing schedules for existing drugs.
Research found that higher light levels increase activity in the posterior hypothalamus, leading to improved cognitive performance during executive tasks. In contrast, lower light levels decreased activity in this region, negatively correlating with cognitive performance.
Researchers found that simulated microgravity significantly disrupted rhythmicity and sleep patterns in humans, leading to reduced sleep duration and increased daytime naps. The study's findings have important implications for future spaceflight and conditions involving prolonged bed rest.
A recent study found that even simple marine polychaete worms, such as Platynereis dumerilii, have unique daily rhythms and behavioral patterns. The researchers discovered that these individual differences can provide an evolutionary edge and increase the resiliency of the species.
The review found women report lower sleep quality, more fluctuations, and higher likelihoods of developing restless legs syndrome and sleep-related eating disorder. Women's brains respond differently to food images after sleep deprivation, with increased emotional processing and activation.
Researchers at INRAE discovered that female sex pheromones can remotely modulate the circadian rhythm of males in the African cotton moth, Spodoptera littoralis. This finding paves the way for exploring biocontrol methods targeting the pest.
A randomized controlled trial reveals that infant gut microbiomes oscillate with a circadian rhythm, detectable as early as 2 weeks after birth. Diet has less impact on the development and composition of the infant microbiome than previously thought.
A study by Hokkaido University and Aarhus University reveals a 'nocturnal' surge in vocalization activity among little auks in Arctic summer, contrary to expectations. The findings provide valuable insights into avian behavior under continuous daylight environments.