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Study identifies potential new treatment target for sleep apnea

Researchers at Johns Hopkins Medicine have identified TRPM7, a cation channel in carotid bodies and bloodstream, as a promising therapeutic target for sleep apnea. Blocking or eliminating this channel may offer a new treatment option for obesity-related breathing disorders.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Channel makeover bioengineered to switch off neurons

Scientists have developed a new tool for controlling brain circuit activity using light pulses, allowing for precise control over neuron function. The breakthrough, funded by the NIH, could lead to future therapeutic applications in managing pain and understanding mental illnesses.

Small change makes a big difference for ion channels

University of Illinois researchers used a high-resolution single-molecule study technique to see subtle differences between two branches of neurotransmitter-gated ion channels. They found that changing the position of an amino acid changes its properties, allowing cation-selective channels to regulate excitation.

New perspectives on ion selectivity

Contributors from different disciplines discuss ion selectivity using crystal structures, electrophysiology, and computational methods. The series provides an ongoing forum for experts to discuss scientific questions and controversies.