Researchers discovered a key protein, BZR1, that regulates plant growth by binding to a specific DNA sequence and stopping the production of an enzyme needed for BR synthesis. This feedback loop helps maintain optimal steroid levels for plant growth.
Research found that altering steroid hormone levels enhances a complex auditory system in female midshipman fish. The discovery suggests that estrogen hormones may play a role in shifting the sensitivity of the auditory system to prioritize social stimuli.
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Researchers at the University of Wisconsin-Madison have found that DHEA significantly increases the division of human neural stem cells, leading to increased neurogenesis. The study's findings provide direct evidence of DHEA's effects on critical human cells, shedding light on the hormone's potential benefits and risks.
A new study found that anabolic steroids can increase lean body mass and reduce fatigue in kidney disease patients receiving dialysis. Patients who received the steroid gained an average of 5.7 pounds more lean body mass than those on placebo, scoring better on physical performance tests.
Researchers found that alendronate significantly increased bone mineral density at the spine and hip in men and women taking steroids, reducing fracture risk. The study showed improved outcomes for post-menopausal women receiving 10mg of alendronate.
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Anabolic steroid use has significantly increased among teenage girls, doubling since 1991, whereas among adolescent boys it has remained nearly unchanged. This trend is attributed to various factors such as the emphasis on physical appearance and competitiveness in sports.
Researchers at UT Southwestern Medical Center found that glucocorticoid can inhibit expression of TNF-alpha gene, halting inflammation and autoimmune diseases like rheumatoid arthritis and lupus. Understanding this mechanism could lead to better drugs with fewer side effects.
Researchers studied genetic mutations in patients with congenital lipoid adrenal hyperplasia, a devastating disorder affecting steroid hormone production. The study revealed that StAR protein plays a central role in steroid hormone synthesis, with mutant proteins blocking cholesterol conversion and causing cellular damage.