A study using functional Magnetic Resonance Imaging identified the neural networks involved in processing reward-related functions modulated by female gonadal steroid hormones. The research found that women exhibit increased reactivity in regions dealing with emotions, such as the amygdalo-hippocampal region, during the follicular phase.
SourceCNRS·JournalProceedings of the National Academy of Sciences·DateFeb 26, 2007
Researchers at the Salk Institute have clarified the response pathway to steroid hormone brassinolide, a key element in plant growth. The study reveals that BES1 is activated in the nucleus after BIN2 inhibition, leading to gene activation and promoting plant growth.
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Researchers investigated whether low serum testosterone levels are associated with low sexual function in women. The study found no evidence of associations between low scores for any sexual domains and low serum total and free testosterone levels.
Researchers discovered a key protein, BZR1, that regulates plant growth by binding to a specific DNA sequence and stopping the production of an enzyme needed for BR synthesis. This feedback loop helps maintain optimal steroid levels for plant growth.
SourceCarnegie Institution for Science·JournalScience·DateJan 27, 2005
Research found that altering steroid hormone levels enhances a complex auditory system in female midshipman fish. The discovery suggests that estrogen hormones may play a role in shifting the sensitivity of the auditory system to prioritize social stimuli.
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Researchers at the University of Wisconsin-Madison have found that DHEA significantly increases the division of human neural stem cells, leading to increased neurogenesis. The study's findings provide direct evidence of DHEA's effects on critical human cells, shedding light on the hormone's potential benefits and risks.
SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateFeb 17, 2004
A new study found that anabolic steroids can increase lean body mass and reduce fatigue in kidney disease patients receiving dialysis. Patients who received the steroid gained an average of 5.7 pounds more lean body mass than those on placebo, scoring better on physical performance tests.
SourceUniversity of California - San Francisco·JournalJAMA·DateApr 14, 1999
Researchers found that alendronate significantly increased bone mineral density at the spine and hip in men and women taking steroids, reducing fracture risk. The study showed improved outcomes for post-menopausal women receiving 10mg of alendronate.
SourceUniversity of Iowa·JournalNew England Journal of Medicine·DateJul 29, 1998
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Anabolic steroid use has significantly increased among teenage girls, doubling since 1991, whereas among adolescent boys it has remained nearly unchanged. This trend is attributed to various factors such as the emphasis on physical appearance and competitiveness in sports.
SourcePenn State·JournalArchives of Pediatrics and Adolescent Medicine·DateDec 15, 1997
Researchers at UT Southwestern Medical Center found that glucocorticoid can inhibit expression of TNF-alpha gene, halting inflammation and autoimmune diseases like rheumatoid arthritis and lupus. Understanding this mechanism could lead to better drugs with fewer side effects.
SourceUT Southwestern Medical Center·JournalMolecular and Cellular Biology·DateOct 22, 1997
Researchers studied genetic mutations in patients with congenital lipoid adrenal hyperplasia, a devastating disorder affecting steroid hormone production. The study revealed that StAR protein plays a central role in steroid hormone synthesis, with mutant proteins blocking cholesterol conversion and causing cellular damage.
SourceUniversity of Pennsylvania School of Medicine·DateDec 20, 1996