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Science News for July 15, 2004


American Thoracic Society Journal news tips for July 2004 (second issue)

Researchers found that lung transplant patients who develop community-acquired respiratory viral infections are at twice the risk of developing bronchiolitis obliterans syndrome. Additionally, a study identified unique tumor signatures that can predict lung cancer death within 12 months with an accuracy rate of 87%.

SourceAmerican Thoracic Society·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateJul 15, 2004

Stem cells get a workout

Researchers have identified a new source of stem cells that can restore dystrophin expression and improve function in dystrophic skeletal muscle. Circulating AC133+ stem cells from humans showed potential in treating muscular dystrophy.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 15, 2004

Mystery of nanoparticles concealed in the blink of an eye

Scientists have developed a method to measure the blinking behavior of large quantities of quantum dots in just a few minutes, revealing new insights into their properties. The approach uses a mathematical tool to analyze light output patterns, allowing researchers to better understand the behavior of these nanocrystals.

SourceUniversity of Chicago·JournalApplied Physics Letters·DateJul 15, 2004

Female infertility cAMP

Researchers created a mouse model with increased cAMP levels in eggs, leading to infertility. By blocking another protein, egg maturation was completed, revealing potential new contraceptive targets.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 15, 2004

Antismoking campaigns, higher prices could save lives

A new study suggests that aggressive antismoking campaigns and higher prices could save thousands of lives by reducing smoking prevalence. By raising cigarette prices and disseminating multimedia antismoking campaigns, smoking rates among adolescents could be reduced by up to 26%, leading to significant life-saving benefits.

SourceCenter for Advancing Health·JournalAmerican Journal of Preventive Medicine·DateJul 15, 2004

Listeria can persist in stores and processing plants

A study by Cornell University researchers found Listeria bacteria on foods in 47 out of 50 retail food stores, with 34% showing persistent strains after re-inspection. The bacteria were also found in seven food-processing plants, highlighting the need for improved control measures to prevent food contamination.

SourceCornell University·JournalJournal of Food Protection·DateJul 15, 2004

Battling the bulge in adolescents

A study found that adolescents who used a web-based intervention to learn about healthy eating had higher self-efficacy for healthy eating and more dietary knowledge compared to those in traditional classes. The results suggest that technology-based activities can be an effective way to promote lifelong healthy eating habits.

SourceBlackwell Publishing Ltd.·JournalJournal of Nursing Scholarship·DateJul 15, 2004

JCI Table of Contents, 15 July 2004

Researchers discovered that human stem cells can replenish muscle fibers in mice with Duchene muscular dystrophy, offering a potential treatment. In contrast, elevated cyclic AMP levels halted egg maturation in females, while HIV protease inhibitors impaired osteoclasts leading to bone loss.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJul 15, 2004

Oregon optics center to build new laser lab

The university's new Laboratory for Quantum Control will enable original experiments at an internationally competitive level, focusing on controlling atoms and molecules using ultrashort light pulses. The lab aims to lead to increased computer capability, improved optical-fiber communications, and new forms of electronics.

Fire on the 'Vomit Comet'

Solid fuel particles may be a safer alternative to gaseous fuels for use in hazardous environments on Earth, as they burn more efficiently in microgravity. Researchers used the NASA 'Vomit Comet' aircraft to simulate weightlessness and measure burning characteristics of various solid fuel particles.

Sponge substance works well with yew derivative to thwart cancer cell proliferation

Researchers find that combining discodermolide and paclitaxel inhibits human lung cancer cell growth by 41 percent, while alone the drugs exert only 9.6% or 16% growth inhibition. The combination also induces programmed cell death in cancer cells, suggesting a potential therapeutic approach for reducing undesirable side effects.

SourceAmerican Association for Cancer Research·JournalCancer Research·DateJul 15, 2004

Gene expression patterns may help predict risk and progression of prostate cancer

Researchers identified 671 genes with altered expression in prostate cancer tissue, revealing a high degree of similarity between benign adjacent tissue and cancerous tissue. The study found that genetic alterations occur throughout the gland, even in seemingly benign areas, providing new insights into prostate cancer progression.

SourceUniversity of Pittsburgh Medical Center·JournalJournal of Clinical Oncology·DateJul 15, 2004

Patients' cells from tumors, the immune system merged for customized cancer therapy

Researchers developed a novel vaccine by fusing patients' tumor cells with their immune system dendritic cells, resulting in increased T cell response against tumor cells. The treatment showed promise in reducing tumor growth and metastasis in late-stage cancer patients, with some experiencing significant regression of tumors.

SourceAmerican Association for Cancer Research·JournalClinical Cancer Research·DateJul 15, 2004