Articles tagged with Triglycerides
Scientists have identified a region on human chromosome 1 that contributes to elevated blood triglyceride levels, increasing the risk of atherosclerosis and heart disease. Three genes, angiopoietin-like 3, leptin receptor, and sterol carrier protein 2, are promising candidates for further study.
A genome-wide study has identified 18 DNA variants associated with blood lipid levels, including six new regions never before linked to cholesterol and triglycerides. These findings hold promise for predicting genetic risk of heart disease and identifying novel targets for cholesterol-lowering therapies.
Researchers found that people with high triglycerides were 2.7 times more likely to have a large artery atherosclerotic stroke than those with low levels. Non-high density lipoprotein cholesterol was also linked to an increased risk of this type of stroke.
Two studies found that elevated nonfasting triglyceride levels are associated with an increased risk of heart attacks, ischemic heart disease, and death. The findings suggest that remnant lipoproteins play a dominant role in postprandial atherosclerosis, and may predict the risk of cardiovascular events in women.
Research suggests a possible association between childhood obesity and otitis media with effusion, characterized by fluid buildup in the middle ear space. The study found higher body mass index (BMI) and total cholesterol levels among children with otitis media with effusion compared to those without the condition.
The study found an unexpected link between the immune system and elevated lipids in mice, suggesting a potential new avenue for studying coronary heart disease. The researchers discovered that altering T cell expression levels significantly impacted cholesterol and triglyceride levels.
Researchers have identified a protein on the inner surfaces of capillaries that delivers dietary fat to enzymes for entry into cells, revolutionizing our understanding of lipid processing. The discovery has implications for patients with chylomicronemia, a condition in which the body's ability to process dietary fat is impaired.
Researchers at UCLA have identified a new protein called GPIHBP1 that plays a crucial role in breaking down fats in the bloodstream. The protein is expressed exclusively on the endothelial cells of capillaries and helps regulate the delivery of lipid nutrients to different tissues.
Studies found that heparan sulfate in the liver plays a crucial role in clearing triglycerides and cholesterol from the blood. The discovery could lead to new treatments for high blood-fat levels and related complications such as arthrosclerosis.
Elevated cholesterol and liver enzyme levels more common than thought among isoretinoin patients, even those with normal blood test results before therapy. Moderate to severe abnormalities are generally transient and reversible.
The gene CGI-58 boosts the activity of adipose triglyceride lipase (ATGL) up to 20-fold, solving a puzzle in lipid storage disease CDS. This activation limits lipid accumulation and restores normal fat breakdown.
Researchers found that baby's genes have a significant impact on mother's lipoprotein levels, which can increase risk of cardiovascular disease. The study suggests that pregnancies may be less affected by maternal genetic defects if the fetus compensates for them.
Researchers discovered that FGF-21 regulates glucose uptake in human fat cells, significantly reducing plasma glucose levels and triglycerides. FGF-21 also protected animals from diet-induced obesity, providing evidence for its therapeutic potential in treating type 2 diabetes.
Researchers have found that fat buildup in the heart muscle, called lipotoxicity, is associated with metabolic irregularities and insulin resistance in obese and diabetic patients. Gene expression and protein findings provide potential long-term targets for treating heart failure, which affects 5 million US patients annually.
Researchers have found that women with visceral fat experience increased lipolysis, the breakdown of fat cells, which can lead to weight loss. The study suggests that this type of fat may be particularly responsive to diet and exercise.
A study found that alcohol exposure during prenatal and postnatal stages may program offspring for insulin resistance and glucose intolerance. Offspring exposed to ethanol showed increased glycemia, decreased insulin sensitivity, and higher triglyceride levels.
A study published in JAMA found that children on the ketogenic diet for six months had significantly elevated cholesterol and triglyceride levels, but these levels often normalized after treatment cessation. The researchers suggest that the diet should remain a treatment option despite short-term lipids elevation.
In a study published in The New England Journal of Medicine, researchers found that Atkins' dieters lost twice as much weight during the first six months compared to those on a conventional low-fat diet. Over time, both groups regained weight, but Atkins' dieters showed greater improvements in blood lipids, including increased HDL chol...
Researchers found that low-dose extended-release niacin improves lipid levels and glycemic control in patients with diabetes. The therapy also raises high-density lipoprotein (HDL) cholesterol, a healthier type of cholesterol.
Researchers found atazanavir significantly lowers total cholesterol, low-density lipoprotein (
Researchers report significant improvements in patients with rare fat disorders who received leptin replacement therapy, including reduced triglyceride levels and liver fat accumulation. The therapy also controlled severe insulin resistance and improved blood glucose levels in most participants.
Researchers found that stress increases triglycerides in the bloodstream, which can contribute to heart disease. Triglyceride levels declined more slowly in stressed volunteers compared to those who rested, suggesting a negative impact of stress on fat metabolism.
Researchers found that apolipoprotein B and A-I were strongly linked to increased risk of fatal heart attack in both men and women. Higher concentrations of ApoA-I had a protective effect, suggesting apolipoproteins may be valuable for diagnosis and treatment.
Postmenopausal women who took n-3 fatty acid-enriched supplements experienced a 26% reduction in serum triglycerides, while those not taking HRT saw a 36% decrease. This suggests that fish-oil therapy may benefit postmenopausal women regardless of hormone replacement therapy use.
Researchers refute earlier research suggesting high triglyceride levels increase heart disease risk in men. In a new study, triglyceride measurements were found to be no help in predicting heart disease in men, unlike women where it was a good predictor of risk of heart attack and death.
A UB study found that obese children are more likely to have high levels of triglycerides and low levels of protective cholesterol, increasing the risk of heart disease later in life. The research, which analyzed data from over 4,000 children, suggests that monitoring body mass index is crucial for early detection of dyslipidemia.
Researchers found that inhibiting triglyceride synthesis, a key step in fat regulation, results in obesity resistance in mice. The study suggests that blocking DGAT-mediated triglyceride synthesis may be a potential strategy for treating obesity.
A recent study found that poorly controlled type 2 diabetic patients are more likely to develop severe periodontal disease, with elevated serum triglycerides contributing to the issue. Reducing cholesterol and serum triglyceride levels through diet and exercise may help improve quality of life and oral health in diabetics.
A genetic abnormality in triglyceride regulation has been found to be common among Asian Indians, placing them at increased risk of heart disease. The study, which analyzed DNA from 100 people, suggests that this abnormality prevents blood fats from being broken down effectively.
Healthy men who used olive oil instead of saturated fats for eight weeks experienced increased triglyceride but lower LDL-cholesterol and clotting factor VII. The long-term significance of this effect on coronary mortality remains unclear.
A new study of 460 adults found that people with triglyceride levels as low as 100 mg/dl were more than twice as likely to suffer from future heart disease. Regular exercise, a diet low in saturated fat, and omega-3 rich foods can help break down fatty deposits in blood vessels.