Articles tagged with X Ray Diffraction
A new algorithm, developed by Cornell University researchers, can reconstruct detailed images of small specimens from raw data using X-ray diffraction microscopy. The algorithm also solves the internationally popular puzzle Sudoku, appealing to its creator's 'whimsical side'.
Scientists at Gladstone Institutes have successfully imaged the native state of apoE4, a key protein in Alzheimer's and cardiovascular diseases. This breakthrough has significant implications for developing future therapeutic interventions by providing a complete understanding of the protein's configuration.
Advanced imaging techniques allow researchers to visualize and analyze the protein-conducting channel with unprecedented detail. The study reveals new insights into the structure and function of this complex biological system.
Researchers analyzed astrolabes from Lahore and found they contained 39-45 weight percent zinc, while European astrolabes had much lower zinc content. The co-melting technique allowed for more precise control over the alloy composition, enabling finer details and more accurate instruments.
A research team from the Max Planck Institute for Metals Research and ESRF observes temporal structural fluctuations on an atomic scale in a crystalline material. The discovery sheds light on how materials respond to external perturbations like changes in temperature, pressure, magnetic or electric fields.
Researchers at the University of Oregon have discovered a way to build a molecular 'claw' that can grab onto arsenic and sequester it, potentially leading to improved treatments for arsenic poisoning. The molecules developed by the team are known as chelators, which enable them to trap and immobilize heavy metal atoms like arsenic.
Researchers have developed a new paint that prevents corrosion by capturing and releasing corrosion-fighting agents when needed. The pigment contains cerium, a natural anti-corrosion mineral, and can be used in conjunction with other corrosion inhibitors to provide enhanced protection.
Researchers have discovered that the DNA copying enzyme, DNA polymerase, retains a "short-term memory" of mismatches and halts itself past the point of the mismatch. The study found that mismatch structures differ dramatically from previous indirect biochemical studies, revealing why stalling occurs.
Elves automates X-ray crystallography process, decreasing time to 19 minutes from days or weeks, increasing efficiency of beamlines. The software uses X-ray diffraction data to produce a 3-D layout of proteins, crucial for understanding their function and designing drugs.
The study found that vinculin changes its shape in response to protein binding, enabling it to regulate cell movement and adhesion. This versatile protein plays a critical role in both healthy development and disease progression, including cancer cell spread.
Researchers at the University of Illinois have developed an algorithm that provides fast and accurate structure determination for organic compounds with a center of symmetry. The new approach reformulates the phase problem into an integer programming problem, allowing for rapid solution finding using off-the-shelf optimization software.
Scientists have successfully imaged a double-wall carbon nanotube at atomic resolution using an electron nanodiffraction technique. This breakthrough enables the determination of the structure of non-periodic objects, including biological macromolecules, much like X-ray diffraction does for crystals.
Scientists have developed a new technique called COBRA to study the structure of thin films at an atomic level, revealing surprising alignment between film and substrate atoms. The technique provides precise information on atomic positions within films and their interactions with substrates.
Scientists have unraveled the mystery of membrane fusion, a process crucial for gene therapy and drug delivery. By analyzing X-ray diffraction patterns, researchers revealed that membrane fusion begins with an hourglass-shaped structure called a stalk.
Researchers used non-traditional techniques to determine nanoscale structures, revealing cesium ions arranged in short-range order zigzag chains. This verifies CsxSi32O64 as a room-temperature stable inorganic electride with potential useful electronic properties.
Scientists at the University of Illinois developed a lensless X-ray microscope that can image microscopic crystals in three dimensions. This technique offers potential for studying nanocrystalline materials and protein crystals, providing new insights into their growth mechanisms.
Researchers have characterized the structure of an Eph receptor tyrosine kinase bound to its corresponding ligand molecule, ephrin. This discovery provides a framework for developing potential drugs that could prevent cancer growth by blocking Eph signaling.
Researchers at Northwestern University determine the molecular structure of a metallochaperone (CCS) bound to its target protein (SOD), providing new insight into a metal transfer mechanism and shedding light on diseases related to copper and oxidative stress.
A team of scientists has unraveled key features of the small ribosomal subunit, including the site where protein biosynthesis begins. The study, which used novel experimental strategies and cryo-crystallography, provides a far-reaching glimpse into the microscopic world of ribosomes.
Researchers created a test-tube photosynthesis system that mimics the metal cluster in green plants, shedding light on how life-giving oxygen is produced. The study, led by University of Delaware chemist Arnold Rheingold, may suggest new strategies for converting sunlight into electricity and enhance our appreciation of the natural world.
Researchers from NASA and French-American teams crystallized thaumatin in space, producing larger and more defect-free crystals with improved x-ray diffraction properties. This breakthrough paves the way for better understanding of the molecule's shape and function, potentially leading to new treatments for diabetes and obesity.
Researchers find that centrosymmetric materials can exhibit triboluminescence when containing impurities or structural anomalies, challenging traditional understanding of the phenomenon. The study synthesized various esters to investigate the relationship between material structure and triboluminescent activity.