Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A natural compound found in tomatoes has been patented and licensed for production as an insect repellent. The substance, IBI-246, is considered slightly safer than DEET and repels a range of insects, including mosquitoes, ticks, fleas, and biting flies.
Researchers from Cornell University deployed acoustic recording units to capture sounds from the Pearl River drainage, but found no indication of the ivory-billed woodpecker's presence. The technology may provide conclusive evidence on future sound recordings.
A Princeton-led study found that 62% of marine iguanas on a Galapagos island died within a year after an oil spill. The researchers believe that beneficial microorganisms in the iguana's guts were killed by the oil, leading to their deaths.
A study found that 39 out of 147 research presentations received prominent newspaper coverage, despite being preliminary findings. The publications record for these presentations was almost identical to the overall publication rate, highlighting the need for scientists to emphasize limitations when interviewed by media.
The ACT EAB believes that this research represents an important milestone in demonstrating the feasibility of new therapies for tissue and organ repair. The board has established strict guidelines for human embryo research, including prohibiting culturing of human embryos in vitro for more than 14 days.
Studies by Johns Hopkins researchers found that excessive myostatin levels cause rapid muscle and fat loss in mice without affecting appetite. This discovery offers hope for new treatments for muscle-wasting diseases like muscular dystrophy and extreme weight loss associated with certain cancers, AIDS, and other conditions.
Researchers found that insects on the same plant were more likely to mate with each other than those on different plants, suggesting habitat plays a crucial role in speciation. The study provides evidence of host-plant adaptation driving reproductive isolation and repeated divergence in this species.
Researchers have successfully used a virus that causes warts to restore LDL receptor function in cells with defective genes, offering new hope for treating familial hypercholesterolemia. The next step is testing this technique in animals and humans to determine its safety and effectiveness.
Rutgers psychologist Gallistel has been elected to the National Academy of Sciences, recognizing his research excellence and contributions to cognitive science. He is credited with introducing the idea that animals can think computationally, enabling them to navigate their world and anticipate events.
Researchers have discovered genetic mutations in dogs that mirror the genetic mutations of humans with inherited blindness, providing new insights into photoreceptor cell degeneration. The study has potential implications for treating both canine and human retinal diseases, including progressive retinitis pigmentosa.
Scientists have discovered that Dlx genes are required for normal mammalian limb development, suggesting homologous genes are responsible for the development of human limbs. The study also identifies two genes, Dlx5 and Dlx6, as candidate genes for split-hand/split-foot malformation (SHFM), a devastating congenital disorder.
New research adds to evidence that acetaminophen may prevent colon cancer in lab animals. The study found that pretreating animals with acetaminophen significantly protected them against cellular changes indicative of colon cancer. However, more animal research is needed before humans can be studied in clinical trials.
Researchers found that some bird species experience population increases when nesting in fragmented landscapes due to the availability of suitable habitats. The study revealed that regional landscape patterns play a significant role in determining population trends among forest-nesting birds.
Harvard Medical School researchers developed a new technique to silence specific proteins in mammalian cells using vector-based RNA interference. This method can be used to complement existing knockout animal models and conduct experiments with cells grown in vitro.
Researchers investigate church records to reconstruct the virulence, spacial diffusion and temporal dynamics of the Black Death. They argue that the disease was transmitted through person-to-person contact, contrary to traditional theories linking it to bubonic plague.
A study by Ohio State University researchers found that farming inside forests reduces bird diversity and nesting success compared to timber harvesting. The study's results suggest that small agricultural openings can have a significant impact on bird populations.
Researchers found that asymmetry is evident in Taita thrush populations before decline, allowing for prediction of vulnerability. Asymmetry increased with habitat disturbance levels, but only certain populations showed a lower survival rate, highlighting the need for conservation action.
Researchers discovered that hibernating squirrels don't exhibit an immune response to bacteria when injected with lipopolysaccharide, but their temperature spikes when they awaken from hibernation to 'check' for infections. This suggests that animals may arouse from hibernation to monitor and combat pathogens in the body.
Researchers have found a way to efficiently study early blood-cell development using the pag-3 gene in both mice and the common worm Caenorhabditis elegans. The study revealed that knocking out genes in mice results in blood formation defects consistent with predictions made by the worm research.
A new blood test was developed using a mouse model of Alzheimer's disease, which can detect amyloid plaques and predict dementia risk. The test uses a protein called Ab40, which is not reflective of brain pathology unless an antibody is injected into the animal.
Researchers from Johns Hopkins Medicine found that removing copper had no effect on the pace of disease in mice with familial ALS-like paralysis. The study used CCS chaperone-deficient mice to rule out copper's role in the disease, suggesting alternative pathways may be responsible for the mutant enzyme's effects on motor neurons.
A study by University of Houston researchers suggests that levels of transport molecules for glutamate increase during learning, indicating an important role in the process. This molecular cleaning crew helps clear away excess neurotransmitters, allowing effective transmission and a non-toxic environment in the brain.
A study analyzing satellite images of the 1999 hurricane flood area found that over 200 NC livestock operations were flooded, contaminating wells and posing a risk to local residents. The research highlights the need for improved monitoring and regulation of industrial animal farms in flood-prone areas.
The new technology uses magnetic resonance microscopy (MRM) to produce 3-D images of mice at unprecedented resolution, revolutionizing the use of mouse models in understanding human disease. Digital 'Visible Mice' will enable researchers to share and analyze animals electronically, facilitating collaboration across distances.
Researchers at Oregon State University have identified a new type of virus in an aborted calf, which is part of the calicivirus family that can infect various species. The discovery raises concerns about the potential spread of disease among livestock and its impact on public health.
Researchers have found that blue whales travel rapidly from one feeding area to another and continue to feed throughout the year. These blue whales move fast, adapting to survive events like El Nino by moving to high-productivity areas quickly.
A study of water striders reveals an evolutionary arms race between males and females, where males use grasping structures to immobilize females, while females develop spines to counteract. This conflict leads to a balance in male and female traits, with some species experiencing high rates of costly matings.
Researchers at the CNRS and INRA Centre de Versailles in France have discovered a gene, SPIK, that increases pollen competitive ability by facilitating rapid pollen tube elongation. This discovery sheds light on how plants can improve their reproductive success.
Researchers at Genetica and Cold Spring Harbor Laboratory have developed a cost-effective method for determining the role of specific genes using RNAi. This approach enables stable silencing of gene expression in mammalian cells, allowing for rapid assessment of gene function, previously limited to plants and certain model organisms.
The Society for Women's Health Research has published proceedings from its Second Annual Conference on Sex and Gene Expression. The conference explored topics such as sex differences in embryonic development, cognitive functions, and mitochondrial DNA. Researchers from various backgrounds shared their findings contributing to the emerg...
Researchers discover antimicrobial peptides in plants and animals, which target bacterial membranes to defend against infections. The study reveals these molecules provide a natural solution to combat growing antibiotic resistance.
A study has discovered an HIV-like virus in a wild chimpanzee, providing evidence that the virus originated from this species. The virus, SIVcpz, was found in one animal from the Gombe National Park, revealing a different strain than previously known viruses.
Researchers have successfully reversed learning impairments in mice with a genetic disorder, neurofibromatosis type 1 (NF1), using an experimental drug. The study provides hope for treating NF1-related learning problems in humans and suggests that a specific amount of Ras activity is crucial for learning.
A new model developed by researchers suggests that the risk of contracting mad cow disease from infected sheep is likely to be higher than from cattle due to stricter control measures. However, implementing regulations such as slaughtering young sheep and banning animal products in feed can reduce this risk significantly.
Researchers at the University of Melbourne are developing crayfish-inspired robots that can navigate complex terrain and perform tasks with minimal brain power. The study aims to advance biomimetics, a field that harvests nature's best design ideas for robotics.
Researchers at NIAID have successfully produced a malaria vaccine using transgenic mice that secrete the vaccine protein in their milk. The vaccine has shown promising results, with only one out of five immunized monkeys contracting the disease.
Scientists discovered a receptor tyrosine kinase in single-celled choanoflagellates, a group of protists with characteristics similar to those of multicellular animals. The finding provides strong support for the hypothesis that choanoflagellates are closely related to metazoans and may represent modern examples of animal ancestors.
University of Colorado researchers have identified a protein called DAF-16 that controls lifespan in roundworms. This protein is part of a complex signaling pathway involving insulin and glucose, and its presence or absence affects an organism's lifespan.
Research at Hope School found that animal-assisted therapy improved mobility, communication, compliance, and attention span in severely disabled children. The study suggested that a team effort among administrators, teachers, and staff is necessary for effective therapeutic interventions.
Researchers have discovered two independent pathways for mRNA export from the nucleus, revealing the role of adapter proteins in regulating this process. The study used cell-permeable peptides to selectively block the action of these proteins, demonstrating their importance in transporting mRNAs for early response genes.
Scientists from Johns Hopkins School of Medicine and Pharmacia have found that mice engineered to produce human COX-2 protein develop age-related memory loss, mirroring problems seen in Alzheimer's disease. The study suggests targeting the protein could prevent neurological diseases.
Researchers from North Carolina State University isolated a new peptide antibiotic from hybrid striped bass mast cells, which could fight important bacterial pathogens in both fish and mammals.
Researchers use SAGE to study fruitfly genome, identifying genes responsive to JNK signal that help skin form properly and understand its effects on a whole organism
Johns Hopkins faculty members Kay Redfield Jamison and Geraldine Seydoux have been awarded the MacArthur Foundation's 'genius' award for their innovative research in psychology and biology. Their work has significantly advanced understanding of mental health treatment, psychiatric disorders, and biological development.
Researchers have found fossil skulls and partial skeletons of the giant Sarcosuchus imperator, which lived during the African Cretaceous period. The species is estimated to have reached its full size in around 50-60 years, suggesting a unique growth pattern that allowed it to attain massive proportions.
Using six years of beetle population data, researchers improved modeling tools for explaining fluctuations in animal numbers. The study found that combining different models and considering lattice effects can provide a more accurate understanding of population patterns.
Researchers found that prion diseases adapt slowly to new species through a prolonged process, making early detection difficult. The study also showed that the disease can spread rapidly in new hosts under specific conditions.
The US Department of Defense has awarded the University of South Florida $4 million to develop a statewide public health system capable of responding to bioterrorism threats. The project aims to create a surveillance system that can detect and track both naturally occurring infectious diseases and potential bioterrorist attacks.
A new study by Cardillo and Bromham found that medium-sized mammals were not at greater risk of extinction, contrary to the widely accepted theory. Instead, small mammal species are the least vulnerable to extinction due to high population densities and reproductive rates.
A study found that the California gnatcatcher, a threatened songbird, does not effectively serve as an umbrella species for coastal sage scrub conservation. The birds occur in nearly all patches, but insect diversity and quality are more closely linked to patch size than bird presence.
Researchers estimate that eastern North American reserves must be at least 1,000 square miles in size to prevent loss of species. This is significantly smaller than the current sizes of most reserves, which are often not enough to safeguard biodiversity.
A recent study found that prescribed burns in eastern U.S. deciduous forests can decline ground-nesting bird species by over 80% due to reduced leaf litter and shrubs. However, two bird species increased in response to the burns, suggesting that fire may improve their foraging habitat.
Researchers found that new collateral blood flow pathways were created in the brain after a minor stroke. This suggests that the brain can recover some blood flow after a small stroke, potentially reducing damage and improving long-term recovery.
Researchers found that ultrasound-induced lung damage is dependent on beamwidth, pulse duration, and exposure duration. The air-blood barrier near the surface of the lung may be the principal target for ultrasound-induced lung damage.
Researchers are investigating the predation habits of Nanomia cara, a gelatinous midwater animal, in the Gulf of Maine. The study aims to determine how this species affects food availability for young cod and other commercially important fishes.
Researchers at Johns Hopkins University have developed a new antimalarial drug that has passed the first stage of preclinical testing in mice and rats. The carboxyphenyl trioxane compound shows good therapeutic index, safety, and efficacy in treating malaria.
A new study found that wood smoke is toxic to certain aquatic organisms in the Great Lakes region. The researchers collected particulate matter samples from different areas along the shores of southern Lake Michigan and found concentrations as low as 10-15 milligrams per liter killed 50% of water fleas within a 24-hour exposure.
Researchers are collecting data on the behavior of Puget Sound's orca whales using novel tools such as a small radio-controlled catamaran and a fish finder. The study suggests that the whales are declining due to a drop in salmon runs and increasing contamination from PCBs.
Researchers found that nepetalactone in catnip is about ten times more effective at repelling mosquitoes than DEET. The compound can be used as an alternative to commercial insect repellents with lower concentrations required, making it a promising discovery for pest control.
Researchers found that humans possess two activated copies of the IGF2R gene, which helps prevent fetal overgrowth and cancer susceptibility. This genetic difference may make human cloning less complicated than other animals.