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Science News Archive 2004 - Page 38


Page 38 of 135

Rare childhood genetic syndrome identified

Researchers have identified a rare genetic syndrome, Timothy syndrome, characterized by cardiac arrhythmias and atypical autism. The syndrome arises from a single gene mutation that impairs a fundamental calcium channel, leading to widespread cellular overloading. Calcium-channel blocking drugs may provide treatment for symptoms.

Phase II trials of second-generation antisense cancer drug planned following successful early study

The second-generation antisense cancer drug OGX-011 has shown promising results in a Phase I trial, inhibiting clusterin production in patients' cancers. The Phase II trials will investigate the effectiveness of OGX-011 combined with standard chemotherapy in patients with metastatic hormone refractory prostate, breast, and lung cancer.

History of smoking significantly reduces survival in head and neck cancer patients

A study published in the Journal of Clinical Oncology found that smokers have a higher risk of death, disease recurrence, and poorer survival rates compared to non-smokers with head and neck cancer. Researchers highlighted the importance of tobacco cessation and moderation of alcohol use to improve quality of life and survival.

SourceAmerican Society of Clinical Oncology·JournalJournal of Clinical Oncology·DateSep 29, 2004

Plants will not save us from greenhouse gases

Researchers led by Graham Bell discovered that increased carbon dioxide concentrations negatively impact algae growth, disproving the notion that plants absorb extra CO2. The study's findings have implications for all plant species, including agricultural ones, as fossil fuel emissions continue to rise.

SourceMcGill University·JournalNature·DateSep 29, 2004