Researchers found topiramate effective in reducing drinking and craving in alcohol-dependent patients who were still drinking. The medication was also shown to decrease plasma GGT levels, a reliable biological marker of heavy drinking.
Researchers found that women experiencing depressive symptoms, binge drinking, or smoking during pregnancy may be at risk for depression and alcohol use during the first postpartum year. Early identification and treatment of these comorbid conditions can benefit both mothers and children.
Researchers found that infant rats willingly ingest large amounts of highly concentrated alcohol during their first exposure, resulting in extremely high blood alcohol levels. This contrasts with adult rats and humans, who typically reject or require initiation procedures to consume alcohol.
Researchers identify three biomarkers from serum proteomic analysis that correctly identified 74% of early-stage ovarian cancers, improving detection capabilities. The test combines these markers with CA125 for enhanced accuracy.
Stanford and Packard researchers found that nicotine patches were equally effective in adolescents regardless of antidepressant medication. Most teens reduced tobacco usage, with some achieving complete abstinence after 10 weeks. The study marks a promising breakthrough in treating teen smoking addiction.
Researchers found that activation of Serine protease inhibitor 2A (Spi2A) can prevent T cell death and increase memory T cells, potentially boosting vaccine efficacy. This discovery could lead to new vaccines or treatments for chronic infections and autoimmune diseases.
Researchers found that ovarian cancer tumors lack response to antiestrogens due to decreased ER beta expression, which can lead to increased cell proliferation and apoptosis. The reintroduction of ER beta in cancer cells induced apoptosis, suggesting its regulatory functions in controlling ovarian cancer growth and motility.
A team of researchers discovered that prions can have a beneficial effect on the evolution of yeast cells, allowing them to survive in new environments. This occurs when prions alter the reading of genetic information, leading to changes in the cell's phenotype.
Research at the University of Pittsburgh School of Medicine found that COPD patients with the most advanced disease are more likely to harbor Pneumocystis jiroveci in their lungs. This colonization is strongly associated with increased airway obstruction and worse lung function, even after adjusting for smoking history.
The identification of the BBS3 gene marks a significant breakthrough in understanding the complex obesity syndrome. By studying the function of the newly discovered protein, researchers hope to unravel the details of other BBS proteins and their potential connections to obesity, learning difficulties, and other related problems.
Researchers at Cedars-Sinai Medical Center found that combining an anti-tumor vaccine with chemotherapy significantly extended patient survival to 26 months on average. The treatment, which involves dendritic-cell immunotherapy, was shown to slow tumor growth and increase the effectiveness of chemotherapy.
A study found that genetic differences are the primary cause of variation in long-term average alcohol intake. Some genes affect both intake and dependence, while others influence only dependence. The research suggests that individuals can make lifestyle choices to improve their health and reduce risk, even with a family history of hea...
A study found that cannabinoids significantly lowered VEGF activity in laboratory mice and patients with late-stage glioblastoma, providing a potential new approach to treating this aggressive form of cancer. The research suggests that cannabinoid-based therapies may target the VEGF pathway, offering a novel pharmacological target.
The US economy is rapidly decelerating due to record deficits and stagnant wage growth. Globalization has led to underconsumption trends in developing countries, while developed nations like the US struggle with low savings rates and rising debt.
A study found that nicotine therapy works as well for teens as for adults when used with behavioral skills training, but the effectiveness drops off for women. In contrast, adult smokers tend to maintain abstinence longer and are more successful in quitting with NRT.