A new imaging method has been developed at Stanford to quickly and accurately locate and count the myriad connections between nerve cells in unprecedented detail. The method, array tomography, combines high-resolution photography with specialized fluorescent molecules to capture information and converts it into imagery.
Researchers from Georgetown University Medical Center presented findings on how a gene regulating dopamine affects communication between brain regions during memory tasks. They also explored the neural processing disrupted in neurological disorders like semantic dementia and stroke, as well as the mechanisms underlying tinnitus.
A new study finds that patients with knee osteoarthritis who also experience lower back or foot pain report more severe knee pain. Additionally, having multiple pain locations, including elbow pain, is associated with higher knee pain scores.
William Ja, a Scripps Florida scientist, received $60,000 grant from the Glenn Foundation to continue his work on longevity-enhancing manipulations. He also received a two-year grant of approximately $200,000 for non-surgical sterilization methods for dogs and cats through the Found Animals Foundation.
Researchers at Queen's University have discovered a way to detect oxygen in complex biomolecular systems, revolutionizing the study of proteins, DNA, RNA and other molecules. This breakthrough allows scientists to examine all four major elements and learn more about their chemical structure and interactions.
Scientists have developed a biodegradable foam plastic substitute using milk protein and clay. The new material is strong enough for commercial use, with almost a third of the material breaking down within 30 days.
A global network to analyze the impact of science on society has been created following an international conference at Universidad Carlos III de Madrid. The network will facilitate communication and collaboration among researchers from diverse fields, including philosophy, sociology, economics, and more.
Researchers at Northwestern University have found a way to mimic estrogen's effects on brain cells without increasing cancer risk. By activating an estrogen receptor, they increased the number of connections between brain cells, improving mental performance.
Researchers at the University of Missouri have developed an intervention strategy that improves medication adherence by three times more than previously studied techniques. The Continuous Self-Improvement strategy involves counseling patients to understand how taking medications fits into their daily routines.
Scientists have discovered two new compounds that show promise as treatments for botulism poisoning, building on a multiple sclerosis drug. The compounds did not enter the brain and showed good potential in mice paralyzed by the toxin.
Researchers discovered that bacteria produce unique proteins to inhibit growth and end life of other bacteria, suggesting a primitive form of kin selection. These proteins are acquired through horizontal gene transfer, allowing bacteria to adapt and evolve.
Rensselaer students Casey Hoffman and Jaron Kuppers won the top prize with their SET process, which offers a new method for curing advanced composites using less energy and cost. The process has the potential to trim manufacturing costs and widen the playing field of businesses that can afford to research and manufacture these materials.
A new study reveals that adenosine tri-phosphate (ATP) works in synergy with lactic acid to sense muscle pain. The researchers found that ATP increases the sensitivity of acid sensing channel #3 (ASIC3) on sensory neurons, helping to explain why acid alone is unable to trigger ischemic pain.
A new device can analyze samples thousands of years old in minutes, helping archaeologists determine ancient activities. It works by lifting off spectral fingerprints with infrared light and analyzing molecular peaks to tease out material origin differences.
Scientists at the University of Cambridge have made breakthroughs in the Haber-Bosch process, aiming to produce fertilizers more efficiently while reducing energy consumption. Their innovative approach uses single-crystal iron samples and ultra-high vacuum conditions to achieve significant improvements.
Dr. Benjamin Kile received the Science Minister's prize for his innovative research into cancer, stem cells and blood cell production. His discoveries have transformed our understanding of platelet biology and hold promise for developing new treatments for life-threatening conditions.
The University of Guam and University of Massachusetts-Boston are partnering to offer a four-year Master's Degree Program for educators in the Pacific, with up to 20 scholarships available. The program aims to enhance educational capacity for students who are blind or have visual impairments.
Reduced pericyte levels have been found to disrupt blood flow and worsen the breakdown of the blood-brain barrier, allowing toxic substances to reach brain tissue. This can lead to structural damage to neurons, impaired learning and memory, and increased risk of neurodegenerative diseases like Alzheimer's.
Researchers found compelling evidence for the birth of a stellar mass black hole in the type IIL supernova SN 1979C. The study proposes that the late time glow of the supernova is consistent with a black hole accreting material from either a fallback disk or a binary companion.
A study published in the Journal of Advanced Nursing found that a nurse practitioner-led spinal clinic achieved 100% agreement on clinical diagnosis and 96% patient satisfaction. Patients waited an average of 12 weeks to see the nurse practitioner, significantly shorter than conventional clinics.
Milan Begliarbekov, a doctoral candidate at Stevens Institute of Technology, has found unique applications for graphene. His research uses µ-Raman spectroscopy to differentiate between monolayer and bilayer graphene, and establishes a new signature of Klein tunneling in graphene heterojunctions.
A multidisciplinary clinic approach to treating aggressive prostate cancer has been shown to improve survival rates and reduce distress among patients. The study, conducted over 15 years at the Kimmel Cancer Center, found that a team of specialists working together can provide more effective treatment options and better patient outcomes.
Research by ecologists at Brown University found that faster water flow speeds promote greater diversity of invertebrate species on rocks under the ocean. The study showed consistent results across three regions, suggesting that water flow is a key factor in determining marine biodiversity.
The Symplicity HTN-2 trial shows that deactivating nerves in the kidneys using radiofrequency energy can significantly reduce blood pressure in patients with treatment-resistant hypertension. The study found a large reduction in systolic blood pressure, and the technique was applied without major complications.
A new analysis by an international team of fisheries scientists found that the widely adopted indicator, average catch trophic level, led to inaccurate conclusions in 13 out of 29 trawl surveys from 14 ecosystems. The study suggests that this measure is a woefully inadequate assessment of marine fisheries health.
The article discusses ongoing research to improve influenza vaccines, including the development of novel production technologies and approaches such as recombinant virus proteins and universal flu vaccines. These efforts aim to provide better protection against multiple strains of influenza and novel flu viruses in the future.
Scripps Research scientists devise broad new technique for screening proteins, enabling efficient detection of functional sites. The method may have applications in basic research and drug development, allowing researchers to characterize unknown proteins and identify new functional sites on existing ones.
Mayo Clinic researchers discovered a connection between two proteins, progranulin and sortilin, which may lead to new treatment options for frontotemporal lobar degeneration. The study found strong associations between genetic variants in the same region of chromosome 1 and plasma progranulin levels.
Children with severe congenital heart defects are twice as likely to experience anxiety at 18 months old compared to healthy peers. The research, conducted by the Norwegian Institute of Public Health, also found that maternal anxiety and depression contribute to these emotional problems.
A new citizen scientist initiative is expanding regional climate modeling efforts, exploring southern Africa, Europe, and the western US, using idle computers of thousands of volunteers. The project aims to fine-tune future climate models by comparing simulations with real data and analyzing changes over the past 50 years.
Researchers have isolated a key hormone, alpha-1, that allows Phytophthora to reproduce, leading to extensive damage to food crops and ornamental plants. The synthesis of a synthetic version of the hormone offers a promising basis for developing an effective method to control the fungus.
Researchers at Caltech have demonstrated quantum entanglement for a four-part quantum state stored in four spatially distinct atomic memories. The team successfully created quadripartite entanglement by entangling the spin waves among four collections of Cesium atoms, which were then transferred to four beams of light.
Researchers argue that racial profiling is fundamentally flawed and no more effective than standard uniform random sampling techniques. It can lead to false assumptions, unfair detention of innocent individuals, and even radicalization.
Researchers identified key proteins controlling centrosome separation, which could prevent uncontrolled cell proliferation in cancer. Combining drugs against different regulators may reduce side effects and improve treatment outcomes.
In a Phase I trial, MK-4827 demonstrated anti-tumour responses in both sporadic and BRCA1/2 mutation-associated cancers. Patients with exhausted standard therapies showed significant shrinkage or stabilization of tumours for extended periods.
Researchers have found that vitamin C can prevent the onset of sepsis and even reverse the disease by restoring blood flow to vital organs. Early and delayed injections of vitamin C have been shown to improve survival rates in mice with sepsis, making it a promising treatment option.
A team of researchers developed a dual scanning tunneling and microwave-frequency probe to study nanoscale interactions, enabling the measurement of physical, chemical, and electronic interactions between single molecules and substrates. The probe can locate and switch single molecule switches on substrates with high resolution.
Researchers have identified a novel oncogene GNA11 associated with uveal melanoma in over 40% of tumor samples. This discovery offers new targets and treatments for the disease, which affects about 1,500 people in the US each year.
Post-traumatic stress disorder (PTSD) is an independent predictor of death from all causes, doubling a veteran's risk of mortality. Researchers found that PTSD veterans had more severe coronary artery disease, with accelerated atherosclerosis being a key mechanism behind the excess mortality risk.
Researchers found that a mutation in the MeCP2 gene leads to the mobilization of L1 retrotransposons in brain cells, reshuffling their genomes and possibly contributing to the symptoms of Rett syndrome. This discovery sheds light on the complexity of molecular events underlying psychiatric disorders such as autism and schizophrenia.
Researchers found boys are more likely to receive an autism diagnosis despite equally severe symptoms, suggesting a gender bias in diagnosis. The study also discovered older mothers are better at identifying their children's difficulties and have more confidence in bringing concerns to the clinic.
Researchers at the University of California, San Diego discover that statins activate white blood cells' ability to kill bacteria. Statins stimulate phagocytes to release extracellular traps that ensnare and kill bacteria before they spread in the body.
The US saw a two-year decline in preterm birth rates, primarily among babies born just weeks early, while many states improved in at least one contributing factor. The overall national rate remains high compared to top-scoring countries.
A new laser system has been developed at Stanford that uses optical coherence tomography to create precise cuts in the lens capsule, increasing safety and precision. The system has undergone clinical trials with no significant adverse events.
The structure of Lassa virus protein reveals how it evades the host's immune system and hijacks infected cells' machinery. Scientists discovered a unique mechanism called cap-stealing, where the virus steals the host cell's RNA cap to suppress interferon production.
A recent study by the University of Delaware found that pelletized manure and no-tillage treatments can significantly reduce estrogen concentrations in manure runoff. The study, published in the Journal of Environmental Quality, suggests that measuring all forms of estrogens is crucial to understanding their environmental impact.
A centralized reference pool could help employers and workers by providing a legal safe harbor for employees and allowing them access to references while also enabling recourse through a neutral third party. This system would promote the flow of accurate information with low transaction costs, making labor markets more efficient.
Researchers found that anthrax bacteria use CMG2 receptors to impair the scavenging action of neutrophils and macrophages, allowing the bacteria to multiply and overwhelm the body's defenses. Studying genetically modified mice revealed that mice without CMG2 receptors on immune cells were completely resistant to infection.
The US Geological Survey estimates approximately 13 million metric tons of rare earth elements exist in known deposits across the country. Significant deposits have been found in 14 states, including California, Alaska, and Wyoming.
Researchers found that dim light exposure caused physical changes in the brains of female Siberian hamsters, including a reduced density of dendritic spines in the hippocampus. This is associated with increased depressive-like behaviors and may be linked to melatonin production.
A team of researchers from the University of Calgary has successfully trapped atomic antimatter, a significant breakthrough in understanding fundamental physics. The discovery opens up new possibilities for studying antimatter and its properties.
A clinical study published in Science Translational Medicine shows the Catalys Precision Laser System significantly improves precision in cataract surgery, reducing risks and enhancing visual outcomes. The system's advanced optics and control software enable surgeons to perform critical steps with greater accuracy.
A five-year study funded by DOD aims to assess the ability of longleaf pine ecosystems to absorb climate-changing carbon dioxide. Researchers will analyze data from Fort Polk, Fort Benning, and Camp Lejeune to develop biologically based models for managing these forests.
Researchers found a 30-50% difference in glial cells between female and male rats, which affected social behavior. Exposure to cannabis-like compounds normalized the difference in play behavior in female rats.
A new study found that ICD patients often do not receive optimal medical therapy, while a promising anti-arrhythmic agent and mobile phone-based telemonitoring system showed significant improvements in heart rhythm and blood pressure control. The study also revealed no increased risk of cancer associated with statin use.
Researchers have developed dual-diameter nanopillars that absorb light as well or even better than commercial thin-film solar cells, using less semiconductor material. The new structure, designed by Ali Javey and his team, enables fine control over geometry and shape of the single-crystalline nanopillar arrays.
A new anti-cancer drug, inecalcitol, has shown encouraging responses in men with hormone-resistant prostate cancer. In a phase II(a) clinical trial, 83% of patients responded to the treatment with a drop in PSA levels of 30% or more within three months.
Researchers at UWM have discovered a potential treatment for cocaine addiction that blocks memory retrieval associated with drug use. The study shows propranolol to be effective in preventing relapse by replacing cocaine-associated memories with neutral associations.
A study using advanced imaging technologies has shed new light on left ventricular non-compaction (LVNC), a cardiomyopathy associated with heart failure, stroke, and arrhythmias. The research reveals that developing cardiac risks appear to progress over time in patients with LVNC.
OpenStudy enables students worldwide to form study groups and connect with peers in real-time, receiving significant gratification from helping others. With over 11,000 users across 151 countries, the platform has already made a notable impact on global education, promoting peer recognition and motivation.