Researchers tested immunotherapy in young and old mice with triple negative breast cancer, finding that age affects the efficacy of ICB therapy. The study found significant reduction in tumor growth and better overall survival rates in young mice compared to aged mice.
A study using Medicare claims data found that Black and Hispanic patients were less likely to visit the same ED as white patients living in the same area. Patients from these racial/ethnic groups were more likely to be transported to a safety-net ED, highlighting disparities in emergency care.
Researchers have identified microRNA-204 as a biomarker for early beta cell death in Type 1 diabetes, which can identify disease onset in children and adults with recent-onset Type 1 diabetes. Serum miR-204 levels were found to be elevated in individuals with Type 1 diabetes and inversely correlated with remaining beta-cell function.
Researchers at University of Utah Health identified large immune cells containing oily droplets in the lungs of vaping patients, enabling faster diagnoses and shedding light on the mysterious condition. The discovery may lead to better treatment options and a deeper understanding of the illness's causes.
Research from the University of Georgia found that adolescents who were not in romantic relationships during middle and high school had good social skills and low depression. Non-dating teens fared equally well or even better than their peers who dated, according to a new study.
A new research group at Charité - Universitätsmedizin Berlin is studying the connection between gut bacteria and high blood pressure. The goal is to develop personalized treatments that improve the gut microbiome's function and prevent organ damage.
Researchers at the University of Münster have developed a new technique that combines two methods to improve the spatial resolution of mass spectrometry imaging. This allows for better understanding of disease processes and potential new strategies for treating them. The technology uses dual-beam laser mass spectrometry, enabling the s...
A study by Texas State University researchers found that horticultural community service programs significantly reduced recidivism rates. The research suggests that participation in these programs can provide a sense of purpose and meaning, leading to a successful transition back into society.
A recent study by researchers at the University of Granada found that 97.4% of footballers in the Spanish League are unfamiliar with banned substances. The study also revealed a high rate of false consensus among players, with 5% admitting to using banned substances and 23.7% knowing their peers had done so.
Tropical Storm Gabrielle has become a post-tropical cyclone over the eastern Atlantic, with heavy rainfall and high winds expected. The storm is forecast to weaken into a remnant low tonight before slowly strengthening into a tropical cyclone by the weekend.
Researchers found that people with schizophrenia employ different brain circuits to overcome initial lack of understanding, leading to increased brain activity in certain areas. The study aims to develop practical skills to help patients with schizophrenia understand metaphors in everyday speech.
A team of mathematicians, led by the University of Bristol and MIT, has finally solved the Sum-Of-Three-Cubes problem for the elusive number 42. Using a 'worldwide computer' harnessing idle computing power from over 500,000 home PCs, they found an answer that took over a million hours to prove.
A team of researchers, including Northwestern University professor Gary Galbreath, analyzed the physical condition of the antlers and confirmed they belonged to a Schomburgk's deer. The antlers showed signs of being fresh, despite being excised from the deer's head, suggesting the deer may still be alive today.
Researchers at Rice University discovered that netting trees to deter birds increases the population of Megalopyge opercularis, also known as asps, which are venomous and can cause severe pain. The study found a 7,300% higher abundance of caterpillars on netted versus non-netted trees.
NASA's Aqua satellite detected a comma-shaped Tropical Storm Faxai using infrared light, revealing the storm's strongest thunderstorms near its center. The powerful storms are expected to bring heavy rainfall to Japan, particularly in the Tokyo area, where landfall is forecast for September 8.
A South African study found a strong link between low language ability and ADHD-type attention problems, as well as depressive symptoms in adolescents. The research highlights the need for better support for children with reduced language ability to prevent long-term mental health issues.
A study analyzed 453,577 US suicides between 1999 and 2016, finding patterns at the county level. The research also uncovered associated geographic and community-level factors contributing to suicide rates.
Hurricane Juliette has been weakening due to NASA-NOAA's Suomi NPP satellite observations, with the strongest storms located in its western quadrant. The storm is expected to become a tropical storm by Friday night and degenerate into a remnant low-pressure area on Sunday.
Scientists have created a way to fully characterize the dynamics of antiferromagnetic materials, enabling faster electronic devices. The approach uses light-based measurement methods and provides unprecedented speeds.
The study reveals that auditory sensory gating filtering begins at the brainstem, contradicting earlier hypotheses. This finding has significant implications for understanding schizophrenia, a condition characterized by difficulty prioritizing and ranking sounds.
Research finds that resilient pregnant women experience fewer pregnancy-related concerns, greater psychological wellbeing, and lower cortisol hormone levels. This protective role of resilience suggests a potential benefit for both the mother and baby.
A new study by Flinders University links moderate to severe childhood behavioral problems to insomnia in adults. The research suggests that early intervention can help manage children's externalized behaviors and reduce the risk of adult insomnia.
A study by the University of Granada recommends spending more time standing to increase energy expenditure and reduce negative health effects of a sedentary lifestyle. Standing burns approximately 45 kilocalories more per six-hour period than sitting or lying down, making it an effective way to combat excess weight and obesity.
A study by Wake Forest School of Medicine found that youth football players with higher vertical jumping ability and faster times in speed and agility drills experience more head impacts, especially during games. The researchers analyzed performance on physical ability tests and on-field head impact data to quantify exposure.
Studies in mouse models reveal that deficiencies in ADAMTS13 and complement activation contribute to thrombotic microangiopathy, a potentially deadly condition. The findings may lead to the development of novel treatment strategies for patients with refractory thrombotic microangiopathy.
A survey of 16,475 households found that raw pet food was a contaminant in only three households, with most common pathogens being Campylobacteria and Salmonella. Most households did not report any infections, with 99.6% reporting no pathogen transmission from raw food.
The employment-to-population ratio for working-age people with disabilities increased from 30.2% to 32%, while that for those without disabilities rose from 73.8% to 74.6%. Project E3: Educate, Empower, Employ provides a comprehensive program serving communities with deep poverty and lowest employment in the US.
A new study found that only a small percentage of men taking long-term opioids were screened for and treated for low testosterone. The research suggests a widespread underscreening for this condition, which can have significant effects on men's health and quality of life.
Researchers at Brigham Young University developed a new wildfire model that uses plant chemistry to predict how quickly wildfires will burn. The study found that the type of shrub species affects the speed of combustion and chemical production, enabling more efficient fire management.
Researchers at Oregon Health & Science University have developed a compound that successfully promotes rebuilding of damaged nerve cell protective sheath, reversing MS symptoms. The discovery may lead to clinical trials in humans with MS or other neurodegenerative conditions.
A three-year grant of 1.2 million rubles will support PhD candidate Angelina Markina's work on efficient algorithms for microstrip antenna design. The project aims to develop mathematical models and prototypes for various frequencies, enabling multi-bandwidth applications including 5G.
Researchers found that heat therapy applied during sleep decreased systolic blood pressure by up to 30 mm Hg in patients with autonomic failure. However, it did not reduce nighttime urine production or morning blood pressure drop. Additional studies are needed to assess the long-term safety and efficacy of this approach.
A University of Michigan study found that a high sugar diet depletes key brain metabolites, affecting behavior and potential connections to depression. The researchers compared fasting and fed fruit flies, discovering rapid changes in brain versus body metabolites.
Researchers from the Salk Institute have discovered how a specific enzyme called chalcone isomerase enables plants to manufacture essential compounds, such as flavonoids, through a unique catalytic process. This knowledge could inform the development of new medicines and improved crops.
Researchers are studying how environmental changes lead to migration and how migrants impact landscapes both at their destinations and origins. Climate change, deforestation, and socioeconomic inequalities are key drivers of this complex relationship, according to Claudia Radel, a geographer and migration researcher.
Researchers at The Wistar Institute have found that ARID1A is essential for telomere cohesion, which helps maintain genomic stability. Inactivation of ARID1A leads to loss of telomere cohesion and selects against gross chromosome alterations.
Researchers from Harvard's Wyss Institute create a new 3D printing method called SWIFT, which allows for the growth of large, vascularized human organ building blocks. The technique enables the creation of viable, organ-specific tissues with high cell density and function.
Argonne scientists develop a new approach to couple magnetization to superconductivity, paving the way for quantum information systems. This breakthrough enables precise manipulation of quantum information through the creation of an 'echo chamber' for energy and quantum information.
A research team has successfully identified an unknown population of the endangered Yamato salamander in Gifu Prefecture, Japan. Using a combined methodology of GIS and eDNA analysis, they discovered five new potential habitats for the species.
Gold-based molecules have shown to be up to 24 times more effective at killing cancer cells than cisplatin and inhibit tumour growth by up to 46.9%. They also target an enzyme linked with cancer progression and have anti-inflammatory properties.
A new model developed by Stevens Institute of Technology researchers can predict how conservation approaches can reduce demand for phosphorus, a vital resource for feeding the world. The model shows that collective diet changes, such as reducing meat consumption or switching to lower-feed meats, can significantly reduce phosphate minin...
Sharareh Kermanshachi is studying third rail insulator failures and developing a workforce development framework for concrete paving experts. Her research aims to improve transportation efficiency and reduce project failures in the US.
Researchers have found a group of antihistamines that can induce differentiation in leukaemic stem cells, leading to cell death. The discovery offers a potential new approach to treating Acute Myeloid Leukaemia (AML), a disease with a high rate of recidivism.
Tropical Storm Akoni quickly transitioned into a post-tropical storm, with NASA capturing its transformation via visible and infrared images. The Moderate Resolution Imaging Spectroradiometer instrument revealed a rounded storm on September 5, while an infrared image showed strong storms southeast of the center on September 6.
A national study found that black and Hispanic patients are more likely to be transported to safety-net hospitals compared to white counterparts living in the same zip code. The research also showed that ambulance diversion practices can exacerbate health disparities.
Researchers found that oral antibiotics can alter human immune responses to seasonal influenza vaccination, potentially hindering protection against infection. Antibiotics also promoted pro-inflammatory states in the body, similar to conditions seen in older adults who have received influenza vaccines.
A new study suggests that chronic conductive hearing loss due to middle-ear infections can lead to neural deficits and difficulties in noisy environments. Researchers found patients with longstanding conductive hearing impairment had lower speech-recognition scores on the affected side, even when speech was audible.
A study of nearly 9,800 NY firefighters suggests an association between greater exposure to the World Trade Center disaster and long-term cardiovascular disease risk. Both acute and repeated exposure during work at the site are linked to higher cardiovascular disease risk compared to those with less exposure.
A study of 211 medical students found over 16% had elevated blood pressure, with nearly 29% having stage 1 high blood pressure. The risk factors include increased waist circumference, stress, lack of exercise, and poor diet.
Researchers at MIT and elsewhere discovered a unique ancient technology for making parchment, which used a mixture of salts found in evaporites. This process helped preserve the Temple Scroll's bright white surface and contributed to its state of preservation.
A national survey study found that 92% of Chinese transgender teens who reported their parents' knowledge of their gender identity experienced parental abuse or neglect. Additionally, 76.6% of all surveyed teens reported abuse or bullying at school from classmates or teachers.
A new study finds that US suicide rates have jumped 41% since 1999, with rural areas bearing the brunt. Factors contributing to higher rates include lack of insurance, gun shop density, poverty, and low social connections.
A new study suggests that older women with chronic illnesses, such as cardiovascular disease or diabetes, may not derive significant benefits from regular screening mammograms. The research found a nearly 90-fold difference in mortality rates between breast cancer and non-breast cancer causes among women aged 75 and older.
The University of Houston Law Center has been awarded a three-year energy research grant to explore ways to facilitate public and private efforts to achieve goals of the Paris Agreement on climate change. The partnership will focus on key global issues in addressing climate change, with faculty members working together to develop new s...
Researchers used neutron scattering to analyze battery electrode reactions and found that lithium sulphide forms on the outer surface of carbon fibres, not within microporous electrodes. This insight could improve battery development with higher energy density and longer lifespan.
Researchers at OHSU are developing a new flu vaccine using the CMV-based platform, which has shown promise in fighting tuberculosis and an HIV-like virus. The goal is to create a longer-lasting, universally effective vaccine that could replace annual shots.
The study successfully overcomes two bottlenecks in the production process by optimizing iron metabolism and using KdcA as a decarboxylase. The engineered yeast strain produces 1.7g/L of 1,2,4-butanetriol, offering a sustainable alternative to petroleum-based production.
The Society of Cannabis Clinicians has named Cannabis and Cannabinoid Research its official journal, expanding its mission to advance the understanding of medical cannabis. The partnership aims to promote rigorous clinical research on cannabis and disseminate new discoveries to practicing physicians and the scientific community.
Hurricane Dorian generated heavy rainfall, with areas receiving over 36 inches of rain accumulation. NASA's satellite data showed the strongest storms were located in cloud tops as cold as minus 70 degrees Fahrenheit.
The GPM core satellite found the heaviest precipitation at a rate greater than 1.6 inches per hour, primarily northwest and northeast of the typhoon's center in fragmented thunderstorms. NASA researches tropical cyclones to provide international partners with data for forecasting.