Researchers have created a detailed map of individual malaria parasite behavior, giving the highest resolution view of malaria parasite gene expression to date. The Malaria Cell Atlas presents possible targets for developing antimalarial drugs, vaccines, and transmission blocking strategies.
Researchers have determined the first atomic structure of the V/A-ATPase family, a key energy machine in cells. The enzyme's structure reveals a turbine-like structure with two or three peripheral stalks and additional connecting protein subunits, enabling greater plasticity and flexibility in its rotation mechanism.
Scientists removed nearly 200 invasive red-eared sliders from a UC Davis Arboretum waterway to observe the impact on native western pond turtles. The study found that without competition, native turtles gain significant weight and improve health.
Researchers develop synthetic compartmentalization system that mimics biological functions, allowing for controlled chemical reactions and separation of materials. The system uses electrical charge to regulate the flow of materials and can be used in various applications such as drug delivery, wound treatment, and water purification.
Dr. Simon Dai's research aims to advance a passive technology that can attract and capture water droplets from fog and moisture in the air, providing a sustainable solution to global water scarcity. The new funding will help create a more durable lubricant for water harvesting.
NASA's Aqua satellite detected a weakened Tropical Storm Chantal, now classified as a depression, with strongest storms shifted to the northeast of the center. The storm is moving eastward at 17 mph and is forecast to slow down and make a clockwise loop through the weekend.
A study found that adults carrying a gene associated with higher Alzheimer's risk had difficulty accessing recently acquired knowledge, despite normal cognitive scores. The research used a listening test to assess attention and memory, revealing greater challenges for individuals with the APOE4 gene.
Researchers have developed a new technology that uses DNA for information processing and storage in living cells. The DOMINO system enables the deep interrogation of biology and can execute cascades of DNA writing events in response to biological signals.
Researchers detected a large unreported Zika outbreak in Cuba during 2017, using virus genomics and travel patterns to identify the outbreak. The study suggests that effective mosquito control campaigns can delay outbreaks, emphasizing the need for alternative detection methods when local case reporting is limited.
Researchers have isolated over 40 different bacteria isolates that can tolerate ocean-level salt content, including Halomonas and Bacillus, which stimulate plant growth in high-saline conditions.
Engineers at UC San Diego and Riverside developed a new ceramic welding method that doesn't require a furnace. The process uses ultrafast pulsed lasers to melt ceramic materials along the interface, creating strong welds.
Researchers propose a new approach to climate change adaptation, focusing on strategic and managed retreat in vulnerable areas. This approach aims to maximize social, economic, and environmental benefits by integrating retreat into broader development goals.
A study by Florida Atlantic University demonstrates the feasibility and efficacy of animal-assisted interventions in reducing stress among military patients undergoing aeromedical evacuation. The results show significant decreases in cortisol levels and improvements in immunoglobulin A levels.
A team of researchers used innovative approaches to calculate the mass of neutrinos, setting an upper limit for the lightest species for the first time. They combined data from various sources, including galaxy observations and particle accelerator experiments, to arrive at a maximum possible mass of 0.086 eV.
Researchers have successfully described what happens when a massive object is placed in a quantum superposition state near clocks, defying classical descriptions. This discovery reveals that quantum time order can arise, leading to new physical effects and potential applications for quantum technologies.
The HADES experiment simulates electromagnetic radiation from colliding neutron stars, revealing temperatures of 800 billion degrees Celsius. The research provides insight into the cosmic kitchen for heavy nuclei fusion.
A novel study found that fatigue symptoms in Parkinson's Disease are associated with low diastolic blood pressure throughout the day. This association may lead to the development of new treatments targeting DBP without exacerbating cardiovascular effects.
Researchers at Harvard's Wyss Institute develop CRISPR-responsive smart materials that can release bound cargo, change structures, or regulate electric circuits. These materials have potential for novel theranostic strategies, point-of-care diagnostics, and regional monitoring of epidemic outbreaks.
A study published in Cell found that intermittent fasting reduces the release of pro-inflammatory cells called monocytes, which can cause serious tissue damage. Fasting also leads to these cells going into a less inflammatory state.
Using a new technique called DOMINO, MIT researchers can store and record complex 'memories' in the DNA of living cells. The system allows for precise editing of DNA bases to encode information, enabling scalable and defined memory systems similar to silicon-based computers.
Tropical Depression 10E has formed in the Eastern Pacific Ocean, with NASA's GOES-West satellite capturing its formation near latitude 15.4 degrees north and longitude 107.3 degrees west. The depression is expected to strengthen over the next couple of days, potentially becoming a tropical storm by tonight and a hurricane by Friday.
A new book from IFPRI researchers reveals that urbanization has spurred growth in nonfarm jobs but little impact on agricultural intensification, with stagnated growth in the non-cocoa sector. Raising land productivity is key to transforming the national economy and ensuring future growth.
Researchers at Princeton University have created new maps that predict coastal flooding for every county on the Eastern and Gulf Coasts. The study finds that 100-year floods could become annual occurrences in Northern coastal towns, primarily due to sea level rise. In more southern latitudes, storms are expected to increase in strength...
A new study found that trainee doctors with dyslexia are less likely to pass the UK GP clinical skills exam, especially if they declare it after failing at least once. The research highlights the need for further investigation into the challenges faced by candidates with dyslexia and potential solutions to support them.
Researchers at the University of Cincinnati discovered that six out of eight extinct Galapagos finch populations had higher genetic diversity than their surviving counterparts. This finding suggests that genetic diversity may not be a reliable predictor of extinction risk for mobile species like finches.
A study in the Atacama Desert found that microbial life can be transported across the hyperarid environment using wind-driven dust particles. This suggests that potential microbial life on Mars may spread similarly, with implications for future research and exploration.
Biomechanics researchers at Georgia Institute of Technology used cockroaches' sprints to develop a method for assessing and improving robot locomotion. The new approach focuses on phase-coupling oscillations, allowing it to work with both insect and robotic systems.
A new index developed from the skin microbiome of children can identify eczema and predict treatment response. The Microbial Index of Skin Health (MiSH) achieved high accuracy in identifying skin conditions across different cities, paving the way for precise skin care.
A recent study found that water availability in soil determines the direction of carbon-climate feedback, with land carbon uptake increasing below optimal moisture levels and decreasing above them. This discovery provides new insights into the complex relationships between climate change, ecosystem dynamics, and water availability.
Despite increasing public and private resources for aquatic ecosystems, decades of watershed restoration projects have had mostly perceived impacts with relatively undocumented or missing data. Researchers suggest setting stricter monitoring standards and partnering with conservation groups to improve water quality measurement.
Scientists found that Nqo1 is necessary for liver cancer cells' ability to thrive by activating key pathways. Blocking Nqo1 dramatically suppresses liver cancer cell proliferation.
A new study projects that future summers in Saudi Arabia will reach extreme danger heat-stress threshold, posing a significant threat to pilgrims. Climate change mitigation initiatives can help reduce the frequency of such events, but adaptations are still necessary to ensure safe Hajj.
Researchers found that individual cortical neurons cannot find order amidst chaotic signals, but the brain averages many neurons' activity for certainty. External inputs can briefly switch networks to a regime of highly reliable spiking, allowing the brain to overcome noise and chaos.
A new research project, Clean Air for a Sustainable Future, aims to develop a concept to achieve significant reduction in soot concentration. The project brings together environmental, social, and health scientists with NGOs, politicians, and affected citizens to find solutions.
Researchers used mosquito genomes to track the Asian tiger mosquito's spread from Albania to Europe, the US, and Africa. Human activities like tire trade facilitated its rapid expansion, posing an increasing public health risk.
A single DNA variant affects the timing of sensory organ development in fruit flies, explaining size trade-offs between eyes and antennae. The study found a conserved genetic mechanism that could apply to sensory organ size variations across animal kingdoms.
African malaria parasites exhibit distinct genetic features in different regions, sharing genes that confer resistance to antimalarial drugs. This study highlights the risk of multi-drug resistance compromising previous success in controlling malaria.
Researchers found that heavy alcohol consumption is associated with altered immune function among people living with HIV, leading to higher levels of biomarkers linked to mortality. The study highlights the potential harms of heavy drinking on people with HIV and emphasizes the need for further research.
Researchers at PSI have developed a new method to precisely measure strong magnetic fields using polarized neutrons. This allows them to visualize and quantify inhomogeneous and anisotropic magnetic fields, with applications in alternators, MRI systems, and other devices.
Researchers at Massachusetts General Hospital have discovered a gene that regulates the behavior of an enzyme involved in Alzheimer's disease, which also causes a rare neurological disorder. The study suggests that targeting this enzyme could lead to new treatments for Alzheimer's.
Researchers have discovered a connection between earthquakes and volcanic eruptions at Mount Aso in Japan. By analyzing very long period seismic waves, they found that earthquakes can trigger changes in pressure variations associated with magmatic activity, leading to eruptions.
A new report by pediatrician Dr. Robert D. Murray supports the inclusion of 100% juice in a healthy diet, citing positive attributes such as retaining key nutrients and bioactives. The study also found that consuming both whole fruit and juice is essential for meeting daily-recommended fruit servings and improving overall diet quality.
Researchers discovered that genetic variations influencing body mass index (BMI) are sensitive to environmental conditions, while those affecting human height are stable across environments. This finding could help determine whether specific traits are influenced by genetics or environment.
Experts propose carefully planned retreat as a tool to achieve societal goals like community revitalization, equity, and sustainability. The approach acknowledges challenges but aims to prepare for long-term adaptation by limiting development in at-risk areas.
A study proposes that the nitrogenase enzyme, essential for photosynthesis, blocked its own activity at 2% atmospheric oxygen levels, stabilizing oxygen levels for nearly two billion years. This negative feedback loop prevented further oxygen production and explains why oxygen levels rose to today's levels.
A leading public health expert warns of systemic failures in the public health system that led to the deaths of 17 elderly patients. The expert draws parallels with two major incidents in the mid-1980s, highlighting the need for strengthened public health and better links between the NHS and local government.
A pioneer study published in PNAS reveals that bacterial sex plays a pivotal role in the evolution of the mammalian microbiome. Horizontal gene transfer, facilitated by temperate bacteriophages, is the primary mechanism driving bacterial evolution in a healthy gut.
Researchers analyzed patient experience surveys from Alberta, Canada, and found areas that are highly rated by patients but also need improvement. Top performing questions included discussing post-discharge needs and receiving written discharge information.
Researchers developed a CRISPR-responsive hydrogel system that can be programmed to release compounds, nanoparticles, or live cells in response to specific DNA targets. The system's sensitivity and versatility make it suitable for various biomedical applications, including tissue engineering, bio-electronics, and biosensing.
Managed retreat can achieve societal goals like community revitalization, equity, and sustainability. However, barriers include financial constraints and psychological issues, which must be addressed through strategic planning and social programs. Implementing equitable relocation policies is crucial to ensure the most vulnerable house...
Researchers are conducting a phase 1 clinical trial using CAR-T cells, which have been shown to attack and kill cancers. The goal is to learn more about how these super-powered immune cells interact with solid tumors to develop effective treatments for various types of cancer.
A WPI mathematician is working on a project to develop methods to detect flaws in carbon nanotube materials used in composite rocket fuel tanks. He has developed an algorithm that increases the resolution of density scanning systems nine times, enabling more accurate images of the material's uniformity.
A large-scale study by Kyushu University researchers found that E. coli bacteria from cattle exhibit characteristics similar to those causing human food poisoning. The findings suggest that these bacterial adaptations may help them thrive in a cattle's intestine, leading to the emergence of new, harmful strains.
Researchers identified a unique way to disrupt cellular process contributing to Diffuse Intrinsic Pontine Gliomas (DIPG). A vulnerability in the metabolic process for creating NAD was found, allowing for potential targeting of cancer cells with PPM1D mutation.
According to a study published in Current Biology, 79 plants have been confirmed extinct from South Africa's three biodiversity hotspots since 1700, representing 45.4% of all known plant extinctions from 10 world hotspots. The main drivers for these extinctions are agriculture, urbanisation, and invasive species.
Researchers from Trinity College Dublin found that lower levels of specific vitamins and antioxidants are consistently associated with frailty in older adults. The study also suggests that micronutrient insufficiencies may act as an easily modified marker for frailty, offering new potential treatments.
Researchers have discovered that particles and even time itself can exist in a state of superposition, blurring the lines between cause and effect. This phenomenon has significant implications for quantum computing, potentially leading to breakthroughs in operations performance.
A Ludwig Cancer Research study reveals that MYC-driven cancers rely heavily on fatty acid synthesis and can be targeted for treatment. The research provides concrete information for the development of new therapies for a broad spectrum of malignancies.
CBD oils may have anti-inflammatory effects and improve sleep and anxiety, but human trials are limited due to concerns over liver injury. Physicians need to become better informed about CBD products to provide effective treatment options for chronic pain management.
Researchers at Weill Cornell Medicine have illuminated the basic mechanism of Piezo proteins, which function as sensors in the body for mechanical stimuli. The discovery provides insights into the roles of Piezo proteins in human diseases and potential new therapeutic strategies.