Researchers from NUS utilised a ground-breaking AI platform to derive an optimal combination of available therapies against SARS-CoV-2, resulting in a treatment that was 6.5 times more effective than remdesivir alone. The top-ranked combination included the drugs remdesivir, lopinavir, and ritonavir at specific doses.
A large cohort study found that dog owners with diabetes are 38% more likely to develop type 2 diabetes than those without. In contrast, no shared risk was detected in cat owners and their cats.
A recent study found that only seven percent of high-risk noncardiac surgery patients underwent preoperative screening for biomarkers, leading to increased mortality and complications. Researchers emphasize the need for improved compliance with guidelines and education among physicians.
A recent paper by Tadeg Quillien outlines a mathematical model of causal judgment that reproduces people's intuitions better than previous models. The study highlights the role of probability and logical structure in shaping our causal intuition, with implications for problem-solving and decision-making.
JILA scientists use an electric 'knob' to control molecular collisions and raise or lower chemical reaction rates in ultracold gases. The ability to manipulate these reactions enables the design of novel chemicals, new platforms for quantum computers, and precision measurement tools.
The Hayabusa2 mission successfully returned asteroid samples from Ryugu, a carbonaceous asteroid believed to contain organic materials. The return marks the second successful sample-return mission in history, offering insights into the origin of life and potential resource utilization for space exploration.
A study by George Mason University and UNC-Chapel Hill found that Black teachers in Chicago Public Schools were unfairly penalized for teaching in low-income neighborhoods with disadvantaged students. Once controlling for school and classroom factors, the racial gap in scores disappeared, highlighting the need to adjust teacher perform...
Scientists discover hematoxylin compounds selectively kill mutated CALR cells, providing hope for new treatment options for primary myelofibrosis patients. The study's results show hematoxylin's ability to disrupt the interaction between mutated CALR and thrombopoietin receptor.
The study assesses an online tool that uses actual virus copy number data to compare pooled and single-sample testing methods. The results show how pooled testing affects population-level outcomes, providing valuable insights for policy makers.
UC Riverside is receiving $6.3 million to combat the deadly fungus Laurel Wilt and other challenges threatening American avocado production. The university will develop next-generation technologies to manage diseases like Phytophthora root rot and soil salinity, which can severely reduce fruit yield and quality.
A new $1 million Federal Government grant will enable a major upgrade to the Murchison Widefield Array, giving the giant radio telescope greater power to process signals from distant outer space. The upgrade will allow researchers to detect finer frequency and time observations, improving their ability to study the universe.
Researchers at Gladstone Institutes and UCSF develop large-scale genetic approach to map protein complex structures in live cells. This breakthrough enables the collection of reliable and detailed structural data reflecting how proteins work in their normal environment.
This survey study assessed German public attitudes toward COVID-19 health communications with varying degrees of scientific uncertainty. The results show that the public is generally skeptical about health messages with high levels of scientific uncertainty.
Researchers developed a non-toxic hydrothermal treatment that enhances conductivity of PEDOT:PSS films by 250 times, making them suitable for biomedical applications.
A recent in vitro study published in Journal of Dietary Supplements found that ergothioneine helped preserve telomere length and reduce oxidative stress. The study suggests that ergothioneine as part of a healthy diet could potentially mitigate the negative effects of oxidative stress and support healthy aging by preserving telomeres.
Astronomers have confirmed an exoplanet, HD 106906 b, with a highly eccentric orbit around its binary star, similar to the hypothetical Planet Nine. The planet's orbit is likely bound, and its presence suggests that distant planets can form within the first tens of millions of years of a star's life.
A team of researchers has successfully grown structures similar to parts of a mouse embryo using a special gel and 3D cell culturing technique. This allows for the investigation of pharmacological agents on a scale that would not be possible in living organisms.
Researchers from Princeton University's Scholes Group discovered quantum vibrations play a crucial role in ultrafast electron transfer reactions. The study uses ultrafast laser spectroscopy to show that vibrations provide channels for the reaction to occur, and an extra vibrational wavepacket appears in the product state.
Researchers at Rice University have developed an Adaptive Learned Bloom Filter (Ada-BF) that can double the throughput of real-time information filters on social media. The new approach applies machine learning in a smarter way to improve the performance of Bloom filters, reducing memory requirements by 50%.
A recent study found that transmembrane protein 41 B (TMEM41B) is essential for SARS-CoV-2 replication. The researchers used CRISPR to inactivate genes in human cells infected with the virus and discovered that TMEM41B was the only molecular feature common to both flaviviruses and coronaviruses, including SARS-CoV-2.
Researchers found that face masks obstruct facial cues, a crucial aspect of effective communication. The loss of visual information significantly impacts native and non-native speakers' ability to understand each other.
Researchers have found that a transmissible cancer affecting Tasmanian devils is shifting from an emerging disease to an endemic one, slowing its spread. The disease appears to be reaching an equilibrium, allowing the population to naturally evolve and possibly resist the cancer.
A study of 13,061 participants aged 60+ found that loneliness and social isolation increase the risk of falls in elderly people. Those living alone or with little social contact were 18-42% more likely to report a fall or hospital admission.
Exercise reduces severity of heart failure, improves heart function, and increases work capacity in rats with heart disease. High-intensity training reverses dysfunctional calcium handling and improves electrical signals in the heart.
A new study suggests that personal appeals from emergency physicians on social media are more effective in changing public attitudes and behaviors than impersonal messages from federal officials. The simulated online study included over 2,000 participants and found that the personal appeal was associated with increased perceived effect...
A recent study by UC San Francisco researchers reveals that ticks possess an antibiotic gene called dae2, which protects them from contracting pathogens, including Staphylococcus bacteria. This discovery provides new insights into the complex interactions between ticks and human skin microbiota.
Researchers at UC Santa Cruz developed a novel serological assay for detecting SARS-CoV-2 antibodies, providing quantitative results in under 20 minutes. The biolayer interferometry immunosorbent assay (BLI-ISA) is as accurate and sensitive as current antibody tests, but faster and less complex.
UTA's David Hunn was selected as a National Academy of Inventors (NAI) fellow for his groundbreaking research in critical thinking and soldier survivability. He credits UTA with teaching him the importance of these skills, which he has applied throughout his distinguished career.
Researchers found that testing long-term memory recall predicted cognitive decline in healthy older people more accurately than classic memory tests. The study also showed that combining this test with an MRI brain scan improved accuracy in predicting Alzheimer's disease risk.
Researchers developed a disposable kit for immediate detection of specific airborne viruses in the field. The platform can sample and monitor airborne viruses simultaneously and detects them within 50 minutes on-site.
Researchers estimate sub-optimal behaviors cost the US healthcare system over $1.3 trillion annually, with a focus on eliminating 'defects' in value. The study proposes a framework to reduce costs and improve care value proposition through targeted interventions.
Researchers at Tokyo Institute of Technology create kinetic model to study site-specific histone modifications and their impact on chromatin accessibility. The model shows that acetylation increases chromatin accessibility threefold, highlighting the potential for accurate quantification of epigenetic effects.
Researchers have discovered that tiny bubbles on electrodes can facilitate electrochemical reactions, leading to faster pollutant removal and chlorine production. The formation of hydroxide anions in the bubble's corona accelerates these processes, making them more efficient than usual.
In a study of Enga society in Papua New Guinea, restorative justice was found to be the dominant approach, with community members playing a key role in resolving disputes. The village courts prioritize repairing harm and reintegrating wrongdoers into society.
Autophagy enables efficient nutrient use and survival in cells by recycling amino acids. The study found that autophagy-derived metabolites, particularly serine, facilitate respiratory growth by supporting one-carbon metabolism and mitochondrial protein synthesis.
Cognitive tests show ravens develop quickly, with skills similar to those of orang-utans and chimpanzees by four months. Ravens excel in tasks requiring addition and relative numbers but struggle with spatial memory.
Entangled photon-based mid-infrared imaging improves penetration depth in highly scattering materials, enabling non-destructive testing and analysis of ceramics and paint samples. The technique produces high-quality 2D and 3D images using a compact optical setup.
A survey is being conducted to characterize marijuana use among cancer patients receiving care at MUSC Hollings Cancer Center. The study aims to explore how often patients are using marijuana, why they're using it, and their perceptions of its efficacy in managing symptoms. The findings will provide insight into the prevalence and spec...
Researchers at the Beckman Institute created a subspace mass spectrometry imaging approach to accelerate data acquisition without sacrificing quality. This technique can detect biomolecules across a wide range of sizes and has implications for analytical chemistry, clinical studies, and neurochemical research.
Researchers at the DOE/Pacific Northwest National Laboratory have developed a process to grow high-performance single-crystal nickel-rich cathodes, overcoming challenges of polycrystalline materials. The new technology identifies the cause of 'crystal gliding' in batteries, which can lead to microcracks and reduced battery lifespan.
A recent study published in Gut journal reveals that beta-blocker treatment can reduce systemic inflammation in patients with advanced liver disease, resulting in fewer complications and lower mortality rates. By targeting portal hypertension, beta-blockers may provide a new therapeutic option for patients with cirrhosis.
A proof-of-concept study found that trained dogs can detect COVID-19 infected individuals by smelling their axillary sweat samples. The researchers used a total of six detection dog teams to identify positive participants with high accuracy.
A new study published in the Journal of the Academy of Nutrition and Dietetics found that exposure to small grocery stores with healthier inventories is associated with significant improvements in childhood obesity. In contrast, increased availability of convenience stores selling predominantly unhealthy foods was linked to a higher li...
Researchers found that listeners can accurately identify regional dialects and racial backgrounds from audio clips of English speakers. The study used 144 unique audio clips to categorize speakers into Midland, New York City, Southern U.S., Asian American, Black/African American, or white groups.
A proof-of-concept study found that 68Ga-pentixafor PET imaging effectively diagnoses and manages rare CNS B-cell lymphoma by targeting the CXCR4 biomarker. The imaging modality showed excellent contrast characteristics between lymphoma lesions and surrounding healthy brain tissue.
Researchers found that introducing native herbivorous crabs to coral reefs in the Florida Keys led to rapid declines in seaweed cover and returned small corals and fishes. The crabs improve habitat conditions for corals and fishes, providing a new tool for reef restoration.
A study published in The BMJ found that dog owners with diabetes are more likely to develop type 2 diabetes themselves than owners without a diabetic dog. However, no shared risk was found between cat owners and their pets.
A new study suggests that targeting the RANK signaling pathway can enhance antitumor immune responses, making breast cancer more responsive to immunotherapy. The findings come from a clinical trial and preclinical research, demonstrating the potential of this approach to convert 'cold' tumors into 'warm' ones.
A team of NYUAD researchers has conducted a comprehensive review of bioluminescence in beetles, including fireflies, identifying structural factors that govern light emission colors. This study may lead to the development of new bioanalytical tools for early disease diagnosis and cancer treatment.
Researchers report a shift towards endemism in Tasmanian devil facial tumor disease (DFTD), a fatal transmissible cancer threatening the species' extinction. The study suggests DFTD may go extinct or coexist with populations, reducing the threat of extinction.
Researchers from Xiamen University demonstrated a bio-inspired heterometallic cluster that mimics the CaMn4O5 structure of PSII, showing efficient overall water splitting activity without sacrificial reagents. The cluster anchors on phosphorus-doped graphitic carbon nitrides and exhibits high H2 production rates and O2 evolution rates.
A new study by Dartmouth researchers calls for stricter regulations on commercial educational websites that expose children to unhealthy food marketing. The team visited popular sites and found ads for sugary cereals and packaged kids' meals, prompting companies like McDonald's and Kellogg to pledge to stop marketing on these platforms.
A new study using AI to examine the fossil record found that mass extinctions rarely create productive periods of species evolution, or 'radiations,' contrary to traditional ideas. Instead, the study suggests that many remarkable times of evolutionary radiation occurred when life entered new environments.
A US study found that patients who undergo surgery on their surgeon's birthday experience higher mortality compared to other days. The researchers suggest that surgeons may be distracted by life events unrelated to work, leading to potential medical errors.
A nationwide study in Germany found that most people want to be informed about the uncertainty in COVID-19 scientific data. The study suggests that communicating uncertainty openly can be more effective than presenting certain information as if it were absolute.
A study found that Zika virus can remain in the mouse brain for extended periods, leading to lasting cognitive impairment and increased risk of psychological disorders. The infection caused long-term deficits in motor function and coordination, as well as anxiety and hyperactivity.
Researchers found that Black churches are trusted messengers of COVID-19 information, with high levels of community engagement and positive feedback. The FAITH! program helped establish emergency preparedness teams and culturally relevant messaging channels within participating churches.
Researchers developed a new model to predict kidney function in cancer patients, enabling more accurate chemotherapy dosing and minimizing harm. The model takes into account various factors like age, gender, and body mass index, providing clinicians with a valuable tool for guiding treatment decisions.
An international team of scientists has produced the first complete, species-level phylogeny of a major group of tropical birds known as suboscine passerines. The study used genetic markers scattered across the entire genome to describe the evolutionary history and create a framework for further questions about mechanisms that drive sp...
Researchers found no slowing of ocean acidification due to COVID-19 emissions reductions, despite a 9% drop in greenhouse gas emissions. However, the study yields important insights on how to track changes in ocean carbon and puts emissions reductions into perspective as short-term gains.