Scientists have created an ultrathin organic solar cell with a high energy conversion ratio of 13% and long-term storage stability. The research used a simple post-annealing process to increase durability, achieving both efficiency and longevity.
Researchers have developed a new method to identify biomarkers for prostate cancer in urine samples, which can help reduce unnecessary biopsies. The test combines multiple components of urine and uses machine learning techniques to accurately predict disease status without invasive biopsy.
A UC Riverside-led study reveals that an interplay of energies at the molecular level enables virus shells to form symmetrically. The research could inform the design of engineered nano-shells used in drug delivery, with potential benefits for targeted treatment and reduced toxicity.
A recent study reveals that natural climate cycles significantly influence the base of the food web along the California coast. Climate changes can alter the timing and prevalence of phytoplankton and harmful algal blooms, which are crucial for understanding ecosystem responses to ocean warming.
A new technology has been used to investigate the cellular processes involved in liver fibrosis development, revealing key genes and cell types that correlate with fibrogenesis. The findings have potential applications for diagnostic tools and therapies.
Researchers have developed a method to synthesize one-handed chiral rotaxanes, which can selectively bind to gold atoms and catalyze chemical reactions. This breakthrough enables the creation of single-handed chiral molecules, addressing potential issues with pharmaceutical drug efficacy.
A study found that robot vulnerability fosters teamwork by encouraging humans to spend more time talking to each other, leading to more positive team dynamics. The results suggest that designing artificial agents to promote social engagement can lead to improved human collaboration.
Research reveals bias and stereotyping among healthcare professionals when recruiting patients for cancer clinical trials. The study highlights language barriers, misconceptions, and negative perceptions of minority participants as challenges. Experts call for culturally tailored approaches to address biases in clinical trial recruitment.
Numerical simulations reveal a 'safety zone' where warmer gas pushes satellites away from their parent planets, explaining the presence of single large moons like Titan. The findings support the idea that many large moons formed along with their parent planets.
A large observational study of nearly 387,000 children found no association between rotavirus vaccination and the development of type 1 diabetes. Researchers noted limitations and potential confounding variables that may have affected results.
Researchers uncovered how approximately 80% of screened cytotoxic compounds rely on solute carriers for activity, providing insights into drug mechanisms and SLC biology. The study also highlights the need for systematic surveys of transporter-drug relationships to develop more effective precision therapies.
Researchers used functional MRI scans to study brain activity while watching videos. Increased activity in certain brain regions predicted whether individuals would continue watching and even forecasted aggregate video view frequency and duration.
Research found that higher levels of sBTLA proteins were associated with poorer overall survival in patients with advanced liver cancer. Treatment with sorafenib revealed dynamic changes in soluble checkpoint protein levels, suggesting potential use as a biomarker for predicting patient outcomes.
Researchers investigated the association between stress-related disorders and neurodegenerative diseases in Sweden's national health registers. Stress-related disorders were found to be associated with an increased risk of these diseases.
Researchers at UCL have developed a new test to identify the earliest genetic changes of prostate cancer in blood plasma. The process, known as DNA methylation, uses Next Generation Sequencing (NGS) to establish if prostate cancer DNA is present in blood plasma.
Researchers at FAU found that belemnites, ancient squid-like creatures, shrank significantly as water temperatures rose during the Toarcian period. The study suggests climate change played a significant role in shaping the morphology of aquatic organisms and may have contributed to their extinction.
A new clinical guideline aims to inform clinicians about evidence-based interventions to treat homeless and precariously housed people. The guideline recommends integrating housing support, income assistance, case management, opioid agonist therapy, and harm-reduction services to address the complex needs of vulnerable populations.
A study of 591 people reveals that prosocial choices initially increase happiness, but this effect is reversed after a month. The findings suggest that prosociality may not always lead to increased happiness.
Scientists propose a new method to produce thermally stable single-atom catalysts (SACs) with high metal loading. The method uses a simple and environmentally friendly approach, achieving kilogram-level production of commercial Fe2O3 supported Ru SACs.
A nationwide study found that racial/ethnic minorities and individuals with lower incomes are less likely to receive office-based care for musculoskeletal conditions, while those with public insurance status are more likely to use emergency department care. This disparity contributes significantly to healthcare expenditures.
Researchers identified a gene, CELSR2, associated with glucocorticoid resistance in leukemia cells. A new drug, venetoclax, may reverse resistance by inhibiting a cell death pathway. The findings suggest combining venetoclax with current therapy could improve ALL chemotherapy effectiveness.
Researchers at Boston Children's Hospital have successfully used gene therapy to reverse cardiac dysfunction and scarring in two mouse models of Barth syndrome. The treatment, which replaced the mutated TAZ gene, prevented progressive cardiomyopathy and restored heart function in both whole-body and heart-only TAZ deletion mice.
Researchers discovered a new master control region in alpha-synuclein protein that controls amyloid formation, leading to neurodegeneration and movement difficulties. This finding opens up new opportunities to develop therapies to slow down or prevent Parkinson's disease.
Scientists create micrometric scaffolding with gold nanoparticles to detect biomarkers and track cell displacement in real time. The SERS technology allows for precise monitoring of tumor growth and evolution, providing insights into cancer treatment.
A recent study published in Nutrients found that 65% of college basketball players were vitamin D insufficient at baseline. Athletes with darker skin pigmentation exhibited heightened risk of vitamin D insufficiency, while those with fair or very fair skin showed no deficiency.
Researchers at Ohio State University analyzed 27 studies on gratitude interventions and found that they had limited value in relieving anxiety and depression. Instead, they recommend treatments like cognitive behavioral therapy for these issues.
A University of Michigan study reveals that ostrich eggshell beads were exchanged over long distances for at least 30,000 years, facilitating relationships between hunter-gatherer groups. The findings provide evidence of a complex exchange network used to share information on resources and landscapes.
Bioscientists at Rice University have developed a novel system to amplify gene expression signals, allowing for more sensitive detection of target genes. The system, consisting of two modules, provides high-resolution dynamic information on gene expression dynamics, which are critical for understanding cell behavior.
A study of 191 patients with confirmed COVID-19 found that older age, sepsis, and blood clotting issues were key risk factors for death. The study also identified the median duration of viral shedding as 20 days in survivors, highlighting the importance of isolation precautions and antiviral treatment.
Research shows that ship noise affects shore crabs' ability to change color and behave normally, reducing their camouflage effectiveness. The study found that juvenile crabs exposed to ship noise changed color half as quickly, making them less camouflaged.
Researchers propose a flexible interface design to reduce alloying stress on silicon anodes, resulting in record-breaking rate performance and cycling stability. The design modulates stress distribution via a soft nylon fabric modified with a conductive Cu-Ni transition layer.
Researchers have developed a new process to produce polyolefins with varying levels of branching, allowing for easier recycling and potentially reducing plastic waste. The method also enables the creation of plastics from natural oils and other substances, addressing environmental sustainability issues.
Sea turtles eat ocean plastics due to their smell, which is caused by a coating of algae and microorganisms on the plastic. This can lead to blockages in their digestive systems and even illness.
Researchers found a polymorphism associated with protective effects against major depressive disorder in women. Microglial cells' immune receptors may play a role in neuropsychiatric disorders.
Researchers at Princeton University identified key factors essential for chronic hepatitis B infection. The study found that five human proteins are necessary for the repair process of HBV DNA, and targeting these factors could potentially prevent the infection.
Researchers at Georgia Institute of Technology have developed a new skin treatment using microscopic STAR particles that can deliver drugs directly to affected areas. The treatment, which involves rubbing the particles on the skin, has shown promising results in inhibiting tumor growth in mice.
A new study by Penn State researchers found that community characteristics play a significant role in determining life expectancy, with factors such as fast food restaurants, population density, and jobs in the extraction industry negatively affecting lifespan. Conversely, social capital, good access to physicians, and lower population...
Researchers discovered a rare eclipsing binary brown dwarf system using the SPECULOOS project, confirming theoretical models of brown dwarfs' cooling processes and providing valuable insights. The system consists of two brown dwarfs orbiting each other, offering opportunities to study their atmospheres and climates.
Researchers found that sea turtles respond to odors from biofouled plastics in the same way they respond to food odorants. This 'olfactory trap' explains why sea turtles ingest and become entangled in plastic debris. Biofouling, the accumulation of microbes on wet surfaces, is a major factor contributing to this attraction.
Around 1 in 20 NHS 111 calls lead to unnecessary emergency care visits, with factors like female sex and young age increasing the risk. The study analyzed 16 million calls and found that 83% of those advised against emergency care still visited within 24 hours.
Weedy rice is a significant threat to global rice productivity, with $45 million annual losses in the US alone. Researchers aim to characterize its genetic basis and traits that enable it to outcompete rice.
Researchers have discovered a novel 'toolkit' of proteins that can repair breaks in DNA, which can lead to cellular ageing, cancer, and neurological diseases. The discovery of the protein TEX264 holds promise for treating cancer and preventing age-related diseases.
A European research network is funding a study to investigate how biological diversity influences chains of infection for mosquito-borne diseases. The project aims to develop reliable risk assessments and identify the impact of biodiversity, landscape diversity, and socio-economic conditions on disease transmission.
The Annual Review of Cancer Biology has converted to open access, making its content freely available worldwide. The move is part of a pilot program called Subscribe to Open, which uses existing library relationships and subscription purchases to convert gated journals to open access.
Pro-vaping and other tobacco videos on YouTube have seen dramatic increases in viewership over the past half-dozen years, despite ad bans. The research highlights the challenges of regulating online content and the potential for social media platforms to influence young people's health information.
A study found that UK hospices provide some form of support before and after parental death, but the type and timing vary widely. Hospices report funding difficulties in training staff for bereavement services, despite national guidelines recommending tailored support.
A breakthrough in optical fiber sensors has enabled the measurement of refractive index outside the cladding of standard fibers, addressing a decades-long challenge. The new concept uses Brillouin dynamic gratings to create acoustic oscillations within the core, allowing for precise measurement and spatially-distributed analysis.
A new UNSW study found that climate change and urbanization are expected to increase groundwater organic carbon, posing a threat to the quality and availability of drinking water for over half of the world's population. Increased groundwater DOC concentrations can lead to higher water treatment costs and health risks.
Researchers from The University of Texas at Austin and Tsinghua University develop a new technology called opto-thermoelectric pulling (OTEP) to achieve the optical pulling of light-absorbing particles. This technique uses directional optical heating to create an asymmetric thermoelectric field, allowing for the trapping of particles a...
A new study of fossil mollusk shells from the late Cretaceous period found that a day lasted 23.5 hours, with ocean temperatures reaching up to 40 degrees Celsius in summer and exceeding 30 degrees Celsius in winter. The ancient shell revealed unprecedented detail about the animal's growth rate and water conditions.
Researchers found that a community-based intervention using mobile vans significantly increased viral suppression, with 74% of participants achieving suppression compared to 63% in traditional clinics. The convenience of the vans made it easier for people living with HIV to access treatment.
Astronomers have discovered a one-sided pulsator in the Milky Way, with citizen scientists providing crucial clues. The star's unusual single-sided pulsation is caused by its location in a binary star system with a red dwarf companion.
A new genetic map of psychiatric disorders has been completed by an international study involving 230,000 patients worldwide. The research identified 109 genetic variants associated with eight psychiatric disorders, including autism, ADHD, and schizophrenia.
Researchers developed twin-chain hydrogels for cleaning artworks, improving efficacy on rough surfaces and reducing pigment loss. The new tool was successfully tested on Jackson Pollock paintings, demonstrating superior cleaning capabilities compared to conventional methods.
New research reveals a worrying change in Indian Ocean surface temperatures, putting southeast Australia on course for increasingly hot and dry conditions. The study, led by Australian National University, suggests that historically rare events have become more frequent and intense during the 20th Century.
Researchers have unveiled the structure and mechanism of a protein critical to DNA packaging in human cells, which is highly overexpressed in various cancers. The study found that this protein facilitates histone loading by utilizing ATP, offering new insights into developing targeted therapies for cancer treatment.
Researchers developed a fluorescence-based technique to monitor single molecules, accelerating structural biology and potentially aiding in structure-guided drug design. The technique uses FRET to visualize biomolecules with unprecedented spatial and temporal resolution.
Researchers examined Hadza adults' activity patterns, finding they spent nearly 10 hours a day in nonambulatory postures similar to industrialized populations. However, Hadza adults spent more time in squatting and kneeling postures, which produce muscle activity, suggesting humans need daily muscle activity from both movement and resting
A study published in Environmental Science and Technology found that wearing clothes can release up to 400 microfibers per gram of fabric during normal activity, while washing clothes can release up to 4,000. This suggests that one person could release almost 900 million polyester microfibers per year through simply wearing garments.
Researchers at Stanford University used brain imaging to forecast how long people will watch videos online. They found that brain responses, not self-reports, predict video popularity. Longer video views were associated with activity in reward-sensitive regions of the brain.