Research found elevated risks between intimate partner violence and childhood sexual abuse and various health conditions. Intimate partner violence was associated with increased risk of major depressive disorders, maternal abortion, and alcohol misuse, while childhood sexual abuse linked to increased risk of self-harm and alcohol use.
A Wayne State University study reports progress in a therapeutic approach that can restore immune surveillance and provide long-term protection against ovarian cancer tumors. The therapy, CARG-2020, has shown promise in animal models and may prove more effective than existing immunotherapies.
Researchers at George Washington University discover protein Snail plays key role in coordinating brain cell responses after injury, with potential to minimize damage and enhance recovery. Additional studies are needed to show increased Snail production could curtail injury or promote healing of the brain.
Researchers discovered a link between ppGpp and sleep regulation in fruit flies, showing that ppGpp is involved in the connection between sleep and starvation. Mutations in Mesh1 gene affected ppGpp degradation, impacting sleep patterns.
The Tokyo University of Science team has created a device that enables the simultaneous evaluation of many cancer cells, allowing for rapid and accurate analysis. The system, called cROT, increases throughput to 2,700 cells per hour, making it more than 100 times faster than traditional methods.
Researchers found several warning signs of abuse, including a partner's behavior and reactions to their decisions, which predicted intimate partner violence. These red flags may be used in interventions to help people avoid abusive relationships or support those at risk.
The study reveals a widespread presence of Bathyarchaeia species in coastal sediments, which encode novel methyltransferases utilizing lignin-derived aromatics. These enzymes facilitate O-demethylation and have significant implications for the marine ecosystem's function and carbon cycling.
A new study found that women-led self-help groups in Odisha, India played a crucial role in maintaining food security during the COVID-19 lockdowns by procuring fresh produce from farmers and selling it to local markets. The groups also provided training and support to their members, enabling them to start their own businesses.
A plant-based diet has been shown to reduce the risk of type 2 diabetes by 24%, with benefits attributed to improved metabolism and liver function. Additionally, healthy eating patterns were found to improve organ function, particularly in individuals with genetic predispositions or other risk factors.
A new study finds that analyzing surgical lymphatic fluid for HPV DNA can predict cancer recurrence and guide treatment decisions. The test was found to be more sensitive than traditional methods, detecting high-risk patients who may be missed by standard tools.
Research reveals that an average of 1,000 times more birds are in the air close to fireworks on New Year's Eve, with effects strongest within the first 5 km. Larger birds like geese and ducks fly for hours at remarkable altitudes, risking accidents.
Research by Staffordshire University found that caffeine can improve short pass accuracy but negatively affect decision-making and long pass accuracy. The study suggests that coaches may need to adjust training strategies to account for caffeine's effects on young soccer players.
Researchers from the University of Technology Sydney have developed a portable, non-invasive system that can decode silent thoughts and turn them into text. The technology has been shown to achieve state-of-the-art performance in EEG translation, with an accuracy score of around 40% on BLEU-1.
Researchers at Linköping University used advanced diffusion MRI to examine the brains of patients with persisting symptoms after COVID-19 and found differences in white matter structure. This study provides new insights into the underlying mechanisms of post-COVID neurological problems.
Researchers found that 195 of 328 bee species collected in Wake County between 1900-2018 were not seen since 1969, likely due to underground nesting habits. Urbanization, climate change, and limited detection methods may be contributing factors.
George Mason University's Ali Raz is leading the development of advanced model-based tools for portfolio management. The project aims to enhance the IAPR System-of-systems tool suite and improve decision-making in autonomous systems.
A new study from the University of Illinois finds that extreme rainfall leads to significant spikes in nutrient concentrations, particularly after ½ inch, 1 inch, and 2 inches of precipitation. However, agricultural management practices such as cover crops can lower nutrient levels in water and persist until the end of the growing season.
Research shows that Australian children are at risk of excessive weight gain and declining fitness during school holidays. The two-year study found that body fat increased at a faster pace and aerobic fitness declined faster than in-school periods. Promoting physical activities during holidays could help address unhealthy weight gain.
A new study warns that public bodies in England and Wales are 'overwhelmed' by the task of implementing human rights laws, with staff placing greater weight on implementation than on understanding the laws themselves. The research suggests that those who view equality and human rights law as malleable are more likely to trust individua...
Researchers at KAIST have developed eco-friendly technologies for producing plastics and processing waste plastics using microorganisms. The team presented the latest microorganism-based technologies that can produce plastics from renewable biomass resources and decompose waste plastics, contributing to a circular economy.
The new Global Burden of Disease report provides an update on the global burden of cardiovascular disease, with Asia, Europe, Africa, and the Middle East having the highest CVD mortality rates. High blood pressure, high cholesterol, and dietary risks remain leading causes.
The ILSI 2024 Annual Meeting will feature scientific presentations, professional development, and networking opportunities focused on innovations for safe, nutritious, and sustainable food manufacturing systems. Press registration is now available for media outlets covering the event.
A study of first-year college students reveals that pandemic stress triggers a rise in clinical depression, even among those with genetic factors that previously shielded them. The research identifies potential predictors of psychological resilience and provides a tool to identify at-risk students for targeted support.
Scientists in Brazil have developed a method to obtain a substance similar to estrogen from soy isoflavones, which may help alleviate menopause symptoms. The researchers extracted equol from soybean oil production residue and found it to be more bioavailable than glycosylated forms.
Researchers at the Francis Crick Institute have identified Cav2.3, a calcium channel, as a potential treatment target for CDKL5 deficiency disorder (CDD), a genetic form of epilepsy that affects early childhood development. The study suggests that inhibiting Cav2.3 could help alleviate symptoms like seizures.
Researchers at Washington State University have developed a single strand of fiber that combines the flexibility of cotton with the electric conductivity of polyaniline. The newly created material showed good potential for wearable e-textiles, including detecting hazardous exposures and tracking human vital signs.
The University of Illinois initiative brings Denali neighbors together in an online discussion forum to share views on protected area conservation and land management. The study finds that engaging diverse stakeholders leads to collaborative dialogue and thoughtful discussions, despite differing priorities.
A large cohort of adolescents found high BMI in late adolescence is associated with early CKD in young adulthood. High-normal BMI and severe obesity also increased the risk of developing CKD.
The São Paulo School of Advanced Science on Quantum Materials will select and support 100 graduate students and young researchers to focus on fundamental, theoretical, and experimental aspects of quantum materials. The program will cover topics like superconductivity, electronic topology, and complex magnetic configurations.
Researchers found that space weather events can trigger 'wrong side' failures in rail signalling systems, which are more hazardous than 'right side' failures. This study highlights the need for the industry to consider the risks of space weather and explore mitigation strategies.
The study reveals that charge density fluctuations affect the electrical resistance of cuprates, making them behave like 'strange' metals. This discovery could pave the way for more environmentally friendly superconducting technologies with higher critical temperatures.
Researchers have developed an ion-exchange method that captures CO2 at room temperature, paired with an electrochemical cell to purify the gas. The technology has the potential to be powered by industrial waste heat or geothermal energy, reducing emissions and costs.
Researchers at Johns Hopkins University found that people can quickly determine what someone is trying to figure out when they shake a box, including the number of items or their shape. This study reveals a key aspect of human cognition and demonstrates how our minds track visual cues.
Researchers at Baylor College of Medicine discovered a new mechanism by which rotavirus induces diarrhea, involving the degradation of DGAT1 enzyme in intestinal cells. This process leads to reduced nutrient absorption and disruption of intestinal function.
Continued treatment with tirzepatide maintained and augmented initial weight reduction in adults with obesity. Withdrawing tirzepatide led to substantial regain of lost weight in a randomized clinical trial involving 670 participants.
Researchers develop a novel protein killer and discover a new ligase for PROTACs, which can specifically target and degrade pathological proteins in specific tissues. This breakthrough could enable the targeted degradation of proteins in tumors.
A new study by Prof. Ehud Meron and colleagues proposes that pairing spatial patterning and phenotypic changes is the missing link to understanding fairy circles. The researchers found that combining plant-level phenotypic changes with population-level spatial patterning can result in resilient ecosystem responses to water stress.
Researchers at Mass General Brigham have developed a new class of proteasome inhibitors that specifically target the β2 active site in cancer cells. The newly synthesized compounds effectively inhibit multiple myeloma cell growth and show promise for reducing therapeutic resistance and side effects when combined with existing drugs.
A study published in the BMJ Christmas Issue investigated the effectiveness of cola in loosening stuck food in the oesophagus. The results show no significant improvement, with only 61% of patients experiencing relief on their own. Cola use was found to have no side effects or complications.
Researchers found that aging can accelerate evolution, favoring faster adaptation to changing worlds. This means senescence becomes an advantageous characteristic under natural selection.
Foraminifera, single-cell organisms with shells, affect oxygen distribution and bacterial diversity in sea sediments through their burrowing. They increase oxygen penetration by 15-20%, decreasing organic matter and bacterial abundance.
The war has caused a significant loss of scientific talent in Ukraine, with approximately 20% of top scientists emigrating. Many scientists who stay are working under precarious contracts or have limited time for research.
A study evaluated sleep tracking performance of various wearable devices against a reference system, considering user needs. Non-EEG wearables showed superior performance for healthy individuals who want to monitor sleep habits.
A new study led by Dr. Mikkael Sekeres found that patients with a common form of acute myeloid leukemia reported better quality of life when treated with quizartinib, which targets the FLT3-ITD mutation. The study also showed minimal side effects and improved survival rates compared to those who didn't receive the drug.
Researchers at Sanford Burnham Prebys identified a molecular signaling pathway that could enhance current MS treatments by linking vitamin B12 deficiency to MS. The study found that supplementing with brain-targeted B12 formulations may improve drug efficacy for this class of medicines.
Researchers identified 26 'driver genes' that play a pivotal role in the transition to stomach cancer, providing a critical window for early detection and targeted prevention. The study's findings offer new insights into the mechanisms governing the transformation of intestinal metaplasia into stomach cancer.
A phase 3 trial found that tirzepatide promotes additional weight loss and preserves metabolic health when continued, but discontinuation leads to significant weight regain. Researchers suggest chronic treatment may be necessary for sustained weight loss and improved cardiometabolic risk factors.
McGill researchers have developed capillaric chips that can be 3D-printed in 30 minutes, enabling on-the-spot testing and potentially making diagnostic tests more accessible. The technology has the potential to speed up diagnoses, enhance patient care, and usher in a new era of accessible testing.
A new commentary in JAMA Pediatrics recommends improving adolescents' media information literacy skills and promoting inclusive content to combat health misinformation spread on social media. This approach aims to harness the potential of social media as a tool for positive connections and mental well-being.
A study published by the American Psychological Association found that people often overestimate the negative ramifications of declining an invitation, but the actual effects are much less severe. The researchers conducted five experiments with over 2,000 participants and discovered that individuals tend to exaggerate the degree to whi...
A phase 2 trial PrE0405 showed an 85% complete response rate in 33 patients over 60 with mantle cell lymphoma who received venetoclax combined with bendamustine and rituximab. The combination was generally well-tolerated, with gastrointestinal toxicities common.
A new deep-learning method, DFINE, can accurately decode brain signals in real time while handling randomly missing signals, enhancing neurotechnologies. This breakthrough advances brain-computer interfaces for treating various neurological and mental health conditions.
Researchers have observed the atmospheres of seven hot Jupiters using NASA's CUTE spacecraft, revealing that some planets lose significant gas while others remain unchanged. The findings suggest a combination of planetary size and stellar activity plays a role in atmospheric escape. CUTE's precise measurements provide valuable insights...
A clinical trial found that the ketogenic diet improved kidney function in patients with polycystic kidney disease, contradicting the long-held belief that it's a genetic disease. The study suggests that controlling the condition through dietary changes can lead to better health outcomes.
A novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods currently in use. The technology has the potential to assess the effects of antiplatelet drugs on individuals and gain a clearer picture of bleeding risks for patients undergoing cardiopulmonary bypass surgery.
A recent study published in JNCCN found that patients from underrepresented groups treated with first-line immunotherapy for advanced Non-Small Cell Lung Cancer (NSCLC) showed similar survival outcomes as their White counterparts. The study analyzed data from 248 patients and highlighted the need for more diverse patient representation...
Prehistoric pottery production discovered to be linked to hunter-gatherer communities, not solely farming, and influenced culinary traditions in Europe. Analysis of pot residues reveals information on cooked products and food processing methods.
Researchers found that a large language model chatbot demonstrated more accuracy in making diagnoses than human clinicians, especially when test results were negative. This suggests the potential for AI to serve as a useful diagnostic partner for physicians, reducing overtreatment and improving decision-making.
Researchers developed novel nanoparticles that deliver RNA to microglia immune cells, reducing inflammation linked to Alzheimer's disease. The study showed a 42% reduction of PU-1 expression and multiple inflammatory markers in human cell cultures and mice models.
Researchers developed a method to measure microvascular changes in the skin using AI and optoacoustic imaging technology, enabling non-invasive assessment of diabetes severity. The study identified 32 significant changes in blood vessels, which can be used to monitor disease progression.