A new study reveals that mothers working from home during the pandemic took on significantly more supervisory parenting responsibilities than fathers, often spending an extra two hours managing childcare duties. The researchers also found that women were more likely to adapt their work schedules to accommodate changing family needs.
Researchers at Berkeley Lab have developed a new method of heating and cooling called ionocaloric cooling, which could provide efficient and safe cooling for homes. The technique uses ions to drive solid-to-liquid phase changes, making it potentially more efficient than current refrigerants.
Researchers from Johns Hopkins Medicine have identified a novel mechanism of tumor formation in kidney cancers, highlighting the role of overactive mTORC1 signaling pathway and loss of the TSC tumor suppressor gene. Activation of microphthalmia transcription factors (MITF) family by unopposed mTOR signaling may lead to abnormal cell gr...
Researchers at Simon Fraser University have identified emerging alternative semiconductors that can enable self-powered, eco-friendly smart sensors for the Internet of Things. These printable electronics have a lower carbon footprint and cost compared to conventional semiconductor technologies.
The proposed project relies on Tensor Network Theory (TNT) to calculate multidimensional problems, offering a less expensive and intensive method than standard computing. Researchers aim to successfully simulate turbulence in compressible fluids and combustion chemical reactions.
Research suggests that social media use in early adolescence may affect the brain's sensitivity to rewards and punishments, potentially influencing psychological adjustment. The study of 169 sixth- and seventh-grade students found associations between habitual checking behaviors on social media and changes in brain development.
The INCOG 2.0 guidelines provide critical updates to address issues in cognitive rehabilitation after traumatic brain injury, including the use of telerehabilitation tools to promote clinical implementation. The guidelines aim to close the evidence-practice gap and improve outcomes for individuals with TBI.
Recent research suggests that age-related macular degeneration (AMD) is a clinical risk factor for severe complications of SARS-CoV-2 infection, including respiratory failure and death. AMD shares common genetic risk factors with COVID-19, and lowering PDGFB gene activity may reduce the severity of COVID-19 in older individuals.
Researchers at Baylor College of Medicine discovered that Grb10 promotes leptin activity in the brain, which may help overcome leptin resistance. This finding suggests that increasing Grb10 activity could lead to weight loss by decreasing food intake and increasing energy expenditure.
Researchers have developed a novel oral drug delivery platform using probiotic bacteria to treat rheumatoid arthritis, reducing the need for lifelong injections. The bioengineered probiotic, LrS235, secretes peptide ShK-235, which dramatically reduces clinical signs of disease in animal models.
A study of 385 patients with a history of multisystem inflammatory syndrome in children found no serious COVID-19 vaccine reactions. The vaccine's safety profile appears comparable to that of the general population, at least 90 days after MIS-C diagnosis.
The procedure requires thorough pre-procedural evaluation and assessment of anatomical and hemodynamic data. Long-term results indicate that TPVR can effectively restore RVOT function, while improving survival rates and reducing the need for reintervention across age groups. Vigilant testing is recommended to avoid rare but serious com...
A study of dual-earner couples in China and South Korea found that working from home can create conflicting demands on both spouses. While wives completed more family-related tasks when working from home, husbands did not complete as many, suggesting a need for flexibility in work arrangements to support working parents.
New expansion microscopy methods, dubbed Magnify, allow researchers to observe nanoscale biological structures with standard microscopes. The protocol retains biomolecules intact, enabling simultaneous imaging of proteins, lipids, and carbohydrates.
Researchers have developed a technique to record cellular events in a long protein chain, allowing them to reconstruct the timing of gene activation, response to drugs, and other processes. This method has potential applications in understanding memory formation, aging, and disease progression.
The CNIC study reveals two distinct mechanisms by which cells detect and respond to forces of varying strength, one mediated by caveolae and the other by newly discovered dolines. This finding has significant implications for understanding pathological processes such as atherosclerosis and neurodegenerative diseases.
The São Paulo School of Advanced Science on Stem Cell Biology will highlight the latest scientific advances in stem cell therapy and tissue bioengineering. Internationally renowned scientists will present state-of-the-art science and results of new research.
MIT scientists use single-cell profiling to analyze the cellular function of brain cells affected by Alzheimer's disease, identifying five main areas of disruption. The study reveals specific molecular programs and gene regulation changes that could lead to valuable biomarkers and therapeutic interventions.
The American College of Physicians recommends bisphosphonates as initial pharmacologic treatment to reduce fracture risk in osteoporosis patients. Long-term use may increase risks, so treatment duration should be limited to 5 years or less.
A recent study found a significant decrease in influenza activity in China during the 2020-2022 COVID-19 pandemic, particularly in winter and spring. The observed reduction in influenza seasonality may be attributed to everyday COVID-19 public health interventions.
A study in California prisons found that recent vaccination and boosters significantly reduced infectiousness of COVID-19, with a 11% decrease per additional dose. Prior infection also provided protection, with a 23% risk of transmission compared to 33% for those who had never been infected.
Researchers found that early prenatal alcohol exposure changes gene function and epigenome in placenta and human embryonic stem cells. These changes are associated with altered DNA methylation patterns, particularly in genes linked to nervous system development, such as DPPA4 and FOXP2.
Adults with higher serum sodium levels were more likely to develop chronic conditions, show signs of advanced biological aging, and die at a younger age. Optimal hydration may be associated with slower aging and reduced risk of chronic diseases.
Researchers at UCSF have developed a novel approach to prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells. By using a decoy receptor, they can capture the antibodies and take them out of circulation before they can kill the therapeutic cells.
A new computer program, DeepMosaic, uses artificial intelligence to detect mosaic mutations in genetic sequences. This method enables accurate detection of mosaic mutations, which cause hundreds of unsolved and untreatable disorders, including epilepsy.
ETH Zurich researchers have created a range of affordable fluorescent inks with machine learning algorithms to determine the right molecular subunits. The new dyes can be used for security features and applications like solar power plants and organic light-emitting diodes.
A new method, SPOTS, maps gene activity patterns and protein presence in cells across tissue samples with unprecedented resolution. This enables the creation of complex maps of organs, including diseased ones, which could be widely useful in basic and clinical research.
A mouse study found that proteins made by stem cells in mice with dry eye disease may be new targets for treating injuries to the cornea. The researchers identified a key gene, SPARC, that is activated in response to injury in dry eye disease and found higher levels of its protein are associated with better healing.
Scientists discover a way to train healthy immune cells to acquire tumor cells' skills for accelerating diabetic wound healing. TAMs-educated macrophages promote cell proliferation, resolve inflammation and orchestrate vasculature.